CN106177773A - A kind of Chinese medicinal pill treating urinary system calculus - Google Patents

A kind of Chinese medicinal pill treating urinary system calculus Download PDF

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Publication number
CN106177773A
CN106177773A CN201610698936.5A CN201610698936A CN106177773A CN 106177773 A CN106177773 A CN 106177773A CN 201610698936 A CN201610698936 A CN 201610698936A CN 106177773 A CN106177773 A CN 106177773A
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radix
urinary system
chinese medicinal
system calculus
medicinal pill
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CN106177773B (en
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李茂坤
彭宣文
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Jingzhou Traditional Chinese Medicine Hospital
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Jingzhou Traditional Chinese Medicine Hospital
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    • A—HUMAN NECESSITIES
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    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The present invention relates to a kind of Chinese medicinal pill treating urinary system calculus, belong to Chinese herbal medicine preparation technology field.The Chinese medicinal pill of this treatment urinary system calculus uses ten Six-element Chinese herbal medicine to make, and utilizes the comprehensive co-action for treating urinary system calculus of ten Six-element crude drug, little to human body side effect, decocts without patient.There is Therapeutic Method easy, cheap, evident in efficacy feature.Prevention and treatment urinary system calculus there is well effect.

Description

A kind of Chinese medicinal pill treating urinary system calculus
Technical field
The present invention relates to a kind of Chinese medicinal pill treating urinary system calculus, belong to Chinese herbal medicine preparation technology field.
Background technology
Urinary stone is the Iithiasic general name of urinary system each several part, is the commonly encountered diseases of urinary system；It includes renal calculus, defeated Ureteral calculi, vesical calculus and calculus of urethra.The traditional Chinese medical science claims damp-heat accumulation blood stasis due to qi deficiency disease, has the kidney or defeated that typical case breaks out Urinary catheter angor, companion's naked eyes or microscopic hematuria；Have a strong impact on the healthy of people.Its morbidity is many and metabolism, diet, environment, with And the many factors such as diseases of urinary system is relevant.At present treatment lithangiuria is with relieving spasm to stop pain, removes calculus, maintain renal function and Prevention of recurrence is principle, takes the circumstances into consideration to carry out operative treatment with calculus size, position, number, complication and systemic conditions and medicine is controlled Treat as treatment means.Existing Drug therapy has that onset is slow, curative effect is undesirable, the problem of the length course for the treatment of；And operative treatment has Costly, the problem of patient suffering；The needs that people fast cure the disease can not be met.
Summary of the invention
It is an object of the invention to: provide a kind of pathogeny for urinary system calculus, eliminating damp-heat, Sal Nitri to lead to Pouring, calculus dissolving and excreting, to reach the Chinese medicinal pill for the treatment of both the principal and secondary aspects of a disease therapeutic interest urinary system calculus.
The present invention is to realize above-mentioned purpose by the following technical solutions:
A kind of Chinese medicinal pill treating urinary system calculus, it is characterised in that: it is made up of the raw material of following weight parts:
Spora Lygodii 4-8 Endothelium Corneum Gigeriae Galli 2-6
Rhizoma Alismatis 4-8 Pheretima 4-8
Lignum Aquilariae Resinatum 1-3 succinum 1-3
Sal Nitri 2-6 Herba Equiseti Hiemalis 4-8
Semen Abutili 8-12 Semen Plantaginis 4-8
Radix Curcumae 4-8 Poria 4-8
Pulvis Talci 15-19 Radix Glycyrrhizae 2-7
Radix Platycodonis 4-8 Radix Cyathulae 4-8
Sucrose 8 12
The preparation present invention treats Chinese medicinal pill preferred weight part ratio range of urinary system calculus:
Spora Lygodii 5-7 Endothelium Corneum Gigeriae Galli 3-5
Rhizoma Alismatis 5-7 Pheretima 5-7
Lignum Aquilariae Resinatum 1-2 succinum 1-2
Sal Nitri 3-5 Herba Equiseti Hiemalis 5-7
Semen Abutili 9-11 Semen Plantaginis 5-7
Radix Curcumae 5-7 Poria 5-7
Pulvis Talci 16-18 Radix Glycyrrhizae 3-6
Radix Platycodonis 5-7 Radix Cyathulae 5-7
Sucrose 9 11
The preparation present invention treats Chinese medicinal pill optimum weight part ratio range of urinary system calculus:
Spora Lygodii 6 Endothelium Corneum Gigeriae Galli 4
Rhizoma Alismatis 6 Pheretima 6
Lignum Aquilariae Resinatum 1 succinum 1
Sal Nitri 4 Herba Equiseti Hiemalis 6
Semen Abutili 10 Semen Plantaginis 6
Radix Curcumae 6 Poria 6
Pulvis Talci 17 Radix Glycyrrhizae 4
Radix Platycodonis 6 Radix Cyathulae 6
Sucrose 10
The preparation method of the Chinese medicinal pill of above-mentioned treatment urinary system calculus comprises the following steps:
1), Spora Lygodii, Semen Plantaginis, Rhizoma Alismatis, Radix Curcumae, Radix Platycodonis, Poria, Endothelium Corneum Gigeriae Galli, Radix Cyathulae, succinum, Lignum Aquilariae Resinatum are pulverized, cross 100 Mesh sieve；Standby；
2), by Herba Equiseti Hiemalis, Semen Abutili, Pheretima, Radix Glycyrrhizae, boiling three times respectively, 1.2 hours for the first time, for the second time, for the third time Each 1 hour, filter afterwards, collecting decoction；
3), above-mentioned decocting liquid is concentrated according to a conventional method；Adding Sal Nitri stirring after cooling makes it dissolve, and filters, is subsequently adding step 1) medicated powder through general ball, be dried, Talcum, sucrose jacket, subpackage,；The Chinese medicinal pill for the treatment of urinary system calculus.
This product is dragee (concentrated watered pill), and removing sugar-coat is taupe brown；Feeble QI, taste is micro-salty and bitter.
Function cures mainly: heat clearing away, diuresis, change are hard, treating stranguria.For various real strangurias such as stranguria caused by urinary stones.
Usage and dosage: oral, three times on the one, each 5g or follow the doctor's advice.
Points for attention: renal failure person is cautious use of.
Specification: 180g/ bottle
The present invention is based on the research pathogenetic to urinary system calculus of motherland's Chinese medicine and Therapeutic Principle, with reference to modern Chinese medicine The scientific achievement of medicine theoretical research, is made by theory of Chinese medical science prescription that its pill has eliminating damp-heat, Sal Nitri is treating stranguria, the merit of calculus dissolving and excreting Effect.The Spora Lygodii relieving stranguria by diuresis of the present invention, expands urinary tract, helps stone descending, and Endothelium Corneum Gigeriae Galli softening the hard mass lithodialysis, the two is monarch drug altogether.Rhizoma Alismatis Entering kidney, diuresis increases liquid；Pheretima has the merit of clearing away heat and promoting diuresis, also anastalsis, with controlling hematuria, and dilating urethra smooth muscle；Lignum Aquilariae Resinatum has Sending down the abnormal ascending QI receives the merit of kidney kidney-Yang invigorating, can control urine qi stranguria；Succinum has the merit of Huayu Tonglin, can control gonorrhea hematuria；Sal Nitri has fossil to lead to Pouring effect；Herba Equiseti Hiemalis has inducing diuresis for treating stranguria syndrome, the merit of hemostasis；Semen Abutili relieving stranguria by diuresis, for dysuria, odynuria；Semen Plantaginis Relieving stranguria by diuresis；Radix Curcumae promoting QI circulation for relieving depression, control stranguria with blood；Poria promoting diuresis to eliminate damp pathogen；It is clearing away heat and promoting diuresis, descending treating stranguria product, is minister altogether Medicine.The sliding profit of Pulvis Talci is sensible in order to calculus discharge, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, and the two is adjuvant drug altogether.Radix Platycodonis, to open lung qi, receipts is opened down The effect of row, Radix Cyathulae Huayu Tonglin and circulation of qi promoting, control five types of stranguria hematuria, pains in the penis, its descending effect is very strong, and the two is altogether for making medicine.
In the material component that the present invention is above-mentioned, property feature and effect of every component crude drug are as follows:
Spora Lygodii: sweet, cold.Return bladder, small intestine meridian.Inducing diuresis for treating stranguria syndrome.For stranguria marked by chyluria, damp invasion of lower energizer, jaundice due to damp-heat, spit blood, hematuria.
Endothelium Corneum Gigeriae Galli (is fried): sweet, flat.Return spleen, stomach, small intestinal, bladder warp.Invigorating the stomach and promoting digestion, arresting seminal emission.Do not disappear for food stagnation, The enuresis, seminal emission.
Rhizoma Alismatis: sweet, light, cold.Enter kidney, bladder warp.Promoting diuresis to eliminate damp pathogen, expels the heat-evil.Controlling dysuria, wet stopping gathers, in phlegm retention water Resistance, deficiency of kidney yin.
Pheretima: salty, cold.Return liver, kidney, lung meridian.Clearing heat for calming endogenous wind, relievings asthma, dredging collateral, diuresis, coughs for high fanatical hot-tempered, lung-heat Breathe heavily, rheumatic arthralgia, blood stagnancy due to deficiency of QI, accumulation of heat in the urinary bladder.
Lignum Aquilariae Resinatum: acrid in the mouth, hardship, tepor.Return liver, heart channel.Promoting the circulation of QI to relieve pain, during sending down the abnormal ascending QI is adjusted, helping inspiration to relieve asthma.For taste element Weak, abdominal distention asthma, prolonged illness is pained, asthma, cough.
Succinum: sweet is flat.GUIXIN, liver, bladder warp.Tranquillizing and allaying excitement, blood circulation promoting and blood stasis dispelling.For irritability, blood deficiency is palpitated with fear, Menoxenia, urine hematuria, traumatic hemorrhage.
Sal Nitri: bitter, salty, cold.Return spleen, stomach, liver, kidney, large intestine channel.Relieve internal heat anticancer, clearing away summer-heat eliminating stagnation, antiinflammatory detumescent.For losing Poison is anticancer, clearing away summer-heat eliminating stagnation, summer-heat pathogens agglomerating, antiinflammatory detumescent.
Herba Equiseti Hiemalis: sweet, bitter, flat；Return lung, Liver Channel；Wind-dispelling heat-dissipating, improving acuity of vision and removing nebula.Control affection due to external wind and heat, external oculopathy conjunctival congestion, have blood in stool Deng.
Semen Abutili: sweet, cold.Enter large intestine, small intestinal, bladder warp.There is inducing diuresis for treating stranguria syndrome, stimulating milk secretion, intestine moistening.Cure mainly dysuria, Constipation, edema distension, stranguria with blood.
Semen Plantaginis (salt): take clean Semen Plantaginis, processs method (one appendix II D of Chinese Pharmacopoeia) according to saline and fries to playing cracker Time, spray saline fried dry.Sweet, it is slightly cold.Return liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, and improving eyesight is eliminated the phlegm.For water Swelling is full, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, gallbladder meridian.Promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.For Distending pain in the chest and hypochondrium, stagnation of liver-QI has heat, the lower mass in the abdomen of the side of body, damp-warm diseases, and epilepsy is gone mad, jaundice.
Poria: sweet in the mouth, light, property is put down.GUIXIN, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing.For edema, accumulation of water with heat, Deficiency of spleen-YANG and kidneyYANG, deficiency of both the heart and spleen.
Pulvis Talci: sweet, light, cold.Return bladder, stomach warp.Inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore, for damp-heat accumulation, Dysuria, diseases caused by exogenous pathogenic factor summer-heat, skin eczema.
Radix Glycyrrhizae: the flat taste of property is sweet, GUIXIN, lung, spleen, stomach warp.Tool invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, the mitigation property of medicine Merit.
Radix Platycodonis: bitter in the mouth, pungent, property is put down.Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.For cough with copious phlegm, lung abscess vomiting pus, The stagnation of phlegm stagnation of QI, exopathogen violates lung.
Radix Cyathulae: bitter, micro-sweet, flat.Return liver, kidney channel.Blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness.For blood stasis amenorrhea, hematuria, traumatic injury Damage, damp invasion of lower energizer, articular instability.
The present invention having the beneficial effects that compared with prior art:
The Chinese medicinal pill of this treatment urinary system calculus uses ten Six-element Chinese herbal medicine to make, and utilizes the comprehensive association of ten Six-element crude drug Same-action treatment urinary system calculus, little to human body side effect, decoct without patient.There is Therapeutic Method easy, cheap, Feature evident in efficacy.Prevention and treatment urinary system calculus there is well effect.
In order to the present invention curative effect to urinary system calculus is described, the present invention is randomly divided into 150 experiments to 300 patients Organizing 150 matched groups and carry out clinical treatment observation, experimental group 150 patient takes pill prepared by the present invention；Matched group is taken general Logical calculus medicine, its clinical data is as follows:
Efficacy assessment standard:
Cure: B ultrasonic display calculus grain is discharged, obstruction of urinary system and the infection etc. such as lumbago angor, hematuria, frequent micturition, urgent micturition, dysurea Clinical symptom disappearance.
Effective: B ultrasonic display calculus grain has reduced, above-mentioned clinical symptom relief.
Invalid: B ultrasonic display calculus grain is unchanged, and above-mentioned clinical symptoms does not alleviates.
3, therapeutic effect such as following table:
Detailed description of the invention
First each raw material of Chinese medicine is weighed by the weight of following table:
Its preparation method is:
Spora Lygodii, Semen Plantaginis, Rhizoma Alismatis, Radix Curcumae, Radix Platycodonis, Poria, Endothelium Corneum Gigeriae Galli, Radix Cyathulae, succinum, Lignum Aquilariae Resinatum are pulverized, crosses 100 mesh Sieve；Standby.By Herba Equiseti Hiemalis, Semen Abutili, Pheretima, Radix Glycyrrhizae, boiling three times respectively, 1.2 hours for the first time, for the second time, the 3rd Secondary each 1 hour, filter afterwards, collecting decoction.
The decocting liquid of merging is concentrated according to a conventional method；Adding Sal Nitri stirring after cooling makes it dissolve, and filters, is subsequently adding powder Medicated powder after broken through general ball, be dried, Talcum, sucrose jacket, subpackage,；The Chinese medicinal pill for the treatment of urinary system calculus.

Claims (3)

1. the Chinese medicinal pill treating urinary system calculus, it is characterised in that: it is made up of the raw material of following weight parts:
Spora Lygodii 4-8 Endothelium Corneum Gigeriae Galli 2-6
Rhizoma Alismatis 4-8 Pheretima 4-8
Lignum Aquilariae Resinatum 1-3 succinum 1-3
Sal Nitri 2-6 Herba Equiseti Hiemalis 4-8
Semen Abutili 8-12 Semen Plantaginis 4-8
Radix Curcumae 4-8 Poria 4-8
Pulvis Talci 15-19 Radix Glycyrrhizae 2-7
Radix Platycodonis 4-8 Radix Cyathulae 4-8
Sucrose 8 12.
The Chinese medicinal pill for the treatment of urinary system calculus the most according to claim 1, it is characterised in that: it is by following weight parts Raw material make:
Spora Lygodii 5-7 Endothelium Corneum Gigeriae Galli 3-5
Rhizoma Alismatis 5-7 Pheretima 5-7
Lignum Aquilariae Resinatum 1-2 succinum 1-2
Sal Nitri 3-5 Herba Equiseti Hiemalis 5-7
Semen Abutili 9-11 Semen Plantaginis 5-7
Radix Curcumae 5-7 Poria 5-7
Pulvis Talci 16-18 Radix Glycyrrhizae 3-6
Radix Platycodonis 5-7 Radix Cyathulae 5-7
Sucrose 9 11.
The Chinese medicinal pill for the treatment of urinary system calculus the most according to claim 1 and 2, it is characterised in that: it is by following heavy The raw material of amount part is made:
Spora Lygodii 6 Endothelium Corneum Gigeriae Galli 4
Rhizoma Alismatis 6 Pheretima 6
Lignum Aquilariae Resinatum 1 succinum 1
Sal Nitri 4 Herba Equiseti Hiemalis 6
Semen Abutili 10 Semen Plantaginis 6
Radix Curcumae 6 Poria 6
Pulvis Talci 17 Radix Glycyrrhizae 4
Radix Platycodonis 6 Radix Cyathulae 6
Sucrose 10
The preparation method of the Chinese medicinal pill of above-mentioned treatment urinary system calculus comprises the following steps:
1), Spora Lygodii, Semen Plantaginis, Rhizoma Alismatis, Radix Curcumae, Radix Platycodonis, Poria, Endothelium Corneum Gigeriae Galli, Radix Cyathulae, succinum, Lignum Aquilariae Resinatum are pulverized, cross 100 Mesh sieve；Standby；
2), by Herba Equiseti Hiemalis, Semen Abutili, Pheretima, Radix Glycyrrhizae, boiling three times respectively, 1.2 hours for the first time, for the second time, for the third time Each 1 hour, filter afterwards, collecting decoction；
3), above-mentioned decocting liquid is concentrated according to a conventional method；Adding Sal Nitri stirring after cooling makes it dissolve, and filters, is subsequently adding step 1) medicated powder through general ball, be dried, Talcum, sucrose jacket, subpackage,；The Chinese medicinal pill for the treatment of urinary system calculus.
CN201610698936.5A 2016-08-22 2016-08-22 A kind of Chinese medicinal pill for treating calculi in urinary system Active CN106177773B (en)

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