CN111819485B - 自动对焦装置和具备其的光学装置以及显微镜 - Google Patents

自动对焦装置和具备其的光学装置以及显微镜 Download PDF

Info

Publication number
CN111819485B
CN111819485B CN201980013041.5A CN201980013041A CN111819485B CN 111819485 B CN111819485 B CN 111819485B CN 201980013041 A CN201980013041 A CN 201980013041A CN 111819485 B CN111819485 B CN 111819485B
Authority
CN
China
Prior art keywords
light
optical system
image
stage
light source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201980013041.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN111819485A (zh
Inventor
安井真人
广岛通夫
上田昌宏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN
Original Assignee
RIKEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN filed Critical RIKEN
Publication of CN111819485A publication Critical patent/CN111819485A/zh
Application granted granted Critical
Publication of CN111819485B publication Critical patent/CN111819485B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals
    • G02B7/30—Systems for automatic generation of focusing signals using parallactic triangle with a base line
    • G02B7/32—Systems for automatic generation of focusing signals using parallactic triangle with a base line using active means, e.g. light emitter
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B13/00—Viewfinders; Focusing aids for cameras; Means for focusing for cameras; Autofocus systems for cameras
    • G03B13/32—Means for focusing
    • G03B13/34—Power focusing
    • G03B13/36—Autofocus systems
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50—Constructional details
    • H04N23/55—Optical parts specially adapted for electronic image sensors; Mounting thereof
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/60—Control of cameras or camera modules

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
  • Studio Devices (AREA)
CN201980013041.5A 2018-02-14 2019-01-24 自动对焦装置和具备其的光学装置以及显微镜 Active CN111819485B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018024408 2018-02-14
JP2018-024408 2018-02-14
PCT/JP2019/002216 WO2019159627A1 (ja) 2018-02-14 2019-01-24 オートフォーカス装置ならびにそれを備える光学装置および顕微鏡

Publications (2)

Publication Number Publication Date
CN111819485A CN111819485A (zh) 2020-10-23
CN111819485B true CN111819485B (zh) 2022-07-29

Family

ID=67619284

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980013041.5A Active CN111819485B (zh) 2018-02-14 2019-01-24 自动对焦装置和具备其的光学装置以及显微镜

Country Status (5)

Country Link
US (1) US11567293B2 (https=)
JP (1) JP7226825B2 (https=)
CN (1) CN111819485B (https=)
DE (1) DE112019000783T5 (https=)
WO (1) WO2019159627A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020171173A1 (ja) * 2019-02-20 2020-08-27 ソニー株式会社 顕微鏡システム、焦点調整プログラム、および焦点調整システム
US12301990B2 (en) 2020-08-07 2025-05-13 Nanotronics Imaging, Inc. Deep learning model for auto-focusing microscope systems
CN113267884B (zh) * 2021-05-24 2022-06-28 凌云光技术股份有限公司 一种多层自动对焦的方法及系统
WO2022265097A1 (ja) * 2021-06-18 2022-12-22 国立研究開発法人理化学研究所 放射線イメージング装置、および放射線イメージング方法
CN114858764B (zh) * 2021-12-29 2024-12-03 郑州思昆生物工程有限公司 一种可自动聚焦的荧光检测系统和自动聚焦方法
JP7036396B1 (ja) * 2021-12-30 2022-03-15 株式会社 Zido オートフォーカス装置
KR20230139684A (ko) * 2022-03-28 2023-10-05 주식회사 스타노스 광학현미경을 위한 자동 초점 장치 및 자동 초점 유지 방법
US20240151937A1 (en) * 2022-11-03 2024-05-09 10X Genomics, Inc. Systems and methods for autofocus
WO2024181542A1 (ja) 2023-03-01 2024-09-06 国立大学法人大阪大学 受容体型チロシンキナーゼの活性評価方法
WO2025224938A1 (ja) * 2024-04-25 2025-10-30 株式会社Zido オートフォーカス装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1089953A (ja) * 1996-09-12 1998-04-10 Olympus Optical Co Ltd 焦点検出装置
CN1269022A (zh) * 1997-08-29 2000-10-04 奥林巴斯光学工业株式会社 显微镜透过照明装置
CN1655000A (zh) * 2004-02-13 2005-08-17 中国科学院力学研究所 一种光学成像系统的角度自动调焦系统及方法
CN103292690A (zh) * 2013-05-29 2013-09-11 浙江大学 一种基于光场选择的合成孔径显微方法和装置
JP2015227940A (ja) * 2014-05-30 2015-12-17 国立研究開発法人理化学研究所 光学顕微鏡システムおよびスクリーニング装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3260712B2 (ja) * 1998-11-30 2002-02-25 日本電気株式会社 フォトマスク修正装置及び方法
JP2003029130A (ja) * 2001-07-11 2003-01-29 Sony Corp 光学式顕微鏡
US20030184856A1 (en) * 2002-04-02 2003-10-02 Nikon Corporation Focus point detection device and microscope using the same
JP2004004634A (ja) * 2002-04-02 2004-01-08 Nikon Corp 焦点位置検出装置およびそれを備えた蛍光顕微鏡
WO2009031477A1 (ja) 2007-09-03 2009-03-12 Nikon Corporation オートフォーカス装置および顕微鏡
JP5189472B2 (ja) * 2008-12-03 2013-04-24 株式会社ミツトヨ レーザ加工装置及びレーザ加工装置における光路調整方法
EP3151052B1 (en) * 2010-02-01 2025-03-26 Illumina, Inc. Focusing methods and optical systems and assemblies using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1089953A (ja) * 1996-09-12 1998-04-10 Olympus Optical Co Ltd 焦点検出装置
CN1269022A (zh) * 1997-08-29 2000-10-04 奥林巴斯光学工业株式会社 显微镜透过照明装置
CN1655000A (zh) * 2004-02-13 2005-08-17 中国科学院力学研究所 一种光学成像系统的角度自动调焦系统及方法
CN103292690A (zh) * 2013-05-29 2013-09-11 浙江大学 一种基于光场选择的合成孔径显微方法和装置
JP2015227940A (ja) * 2014-05-30 2015-12-17 国立研究開発法人理化学研究所 光学顕微鏡システムおよびスクリーニング装置

Also Published As

Publication number Publication date
DE112019000783T5 (de) 2020-11-05
CN111819485A (zh) 2020-10-23
JP7226825B2 (ja) 2023-02-21
WO2019159627A1 (ja) 2019-08-22
US11567293B2 (en) 2023-01-31
US20210041659A1 (en) 2021-02-11
JPWO2019159627A1 (ja) 2021-02-25

Similar Documents

Publication Publication Date Title
CN111819485B (zh) 自动对焦装置和具备其的光学装置以及显微镜
KR102668960B1 (ko) 자동 현미경 초점을 위한 시스템, 장치 및 방법
JP5580206B2 (ja) レーザ光機械加工
US20110157349A1 (en) Stage control device, stage control method, stage control program, and microscope
KR20060004963A (ko) 샘플의 이미징동안 초점위치를 결정하는 방법 및 어레이
US9297994B2 (en) Grating-assisted autofocus device and autofocusing method for an imaging device
JP5053691B2 (ja) 標本スキャナ装置、該装置による標本位置検出方法
JPH10239036A (ja) ３次元計測用光学装置
TW202235195A (zh) 觀察裝置及觀察方法
JPH10239037A (ja) 観察装置
JP7036396B1 (ja) オートフォーカス装置
JP4384446B2 (ja) オートフォーカス方法及びその装置
KR20190063027A (ko) 라인 스캐닝 방식의 공초점 현미경에서의 자동초점조절 방법 및 장치
JPH09230250A (ja) 光学顕微鏡自動合焦点装置
JP2002277729A (ja) 顕微鏡用オートフォーカス装置および方法
JP5145698B2 (ja) 顕微鏡用焦点検出装置と、これを具備する顕微鏡
TWI899824B (zh) 自適應調整之光學取像系統
US12443023B2 (en) Light sheet microscope having streamlined field of view changes
WO2019230215A1 (ja) 撮像装置
JP2024165098A (ja) 光軸調整装置、レーザ照準装置及び光軸調整方法
CN119200193A (zh) 自适应调整的光学取像架构
WO2025224938A1 (ja) オートフォーカス装置
JP2007147756A (ja) 光学測定装置
KR20230087380A (ko) 레이저 가공 장치
JP2016017880A (ja) 標本観察装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant