CN111773337A - Medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and preparation method thereof - Google Patents

Medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and preparation method thereof Download PDF

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CN111773337A
CN111773337A CN202010675563.6A CN202010675563A CN111773337A CN 111773337 A CN111773337 A CN 111773337A CN 202010675563 A CN202010675563 A CN 202010675563A CN 111773337 A CN111773337 A CN 111773337A
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叶金承
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Henan Wuji Institute Of Traditional Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

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  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and a preparation method thereof, and relates to the technical field of medicinal and edible traditional Chinese medicine compositions, wherein the medicinal and edible traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20-40 parts of saussurea involucrate culture, 20-40 parts of coix seed, 2-18 parts of purslane and 2-18 parts of mung bean. The medicinal and edible traditional Chinese medicine composition provided by the invention adopts pure natural raw materials, does not contain additives, has no side effect, can be eaten for a long time, can effectively improve and regulate damp-heat constitution, and has obvious effects on common diseases of patients with damp-heat constitution, such as spleen and stomach damp-heat, liver and gallbladder damp-heat, bladder damp-heat, intestinal tract damp-heat and the like.

Description

Medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and preparation method thereof
Technical Field
The invention relates to the technical field of medicinal and edible traditional Chinese medicine compositions, in particular to a medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and a preparation method thereof.
Background
Damp-heat pertains to two pathogens of six exogenous wind, cold, summer-heat, dampness, dryness and heat, and is the pathogenic factor in TCM.
The damp is divided into internal damp and external damp, and the external damp is caused by the invasion of external water into human body due to damp weather or rain or damp living room, and the pathogenic factors are turbid, viscous and descending. Internal dampness is a pathological product and is related to the dysfunction of the zang-fu organs.
Heat is the pathogenic factor of fire-heat. Heat is also produced by the dysfunction of the zang-fu organs, called internal heat. When the pathogenic fire-heat invades the body or the viscera function disorder of the body generates internal heat, it can cause heat syndrome, which is the condition of feeling external pathogen, or hyperactivity of the body, preponderance of yang and decline of yin. Clinical manifestations of heat syndrome: fever, thirst with desire for cold drink, red face and eyes, scanty and brownish urine, dry stool, red tongue with yellow and dry coating, and rapid pulse.
Damp-heat refers to the condition that heat and dampness invade the human body simultaneously, or pathological changes exist in the human body simultaneously, or the dampness and heat are merged into the human body because of the heavy heat and humidity in summer and autumn, or the dampness is not removed because of the long-lasting dampness. The common clinical manifestations of damp-heat syndrome: fever, lingering fever, headache, heaviness and pain of the body, bitter taste in the mouth, fullness in the chest, yellow and short urine, red tongue with yellow and greasy coating, soft-superficial and rapid pulse. When it invades the zang-fu organs, there appear damp-heat in the spleen and stomach, damp-heat in the liver and gallbladder, damp-heat in the bladder, damp-heat in the intestinal tract, etc.
At present, no symptomatic medicine-food homologous traditional Chinese medicine composition is used for improving the symptoms of people with damp-heat constitution.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and a preparation method thereof.
The medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 20-40 parts of saussurea involucrate culture, 20-40 parts of coix seed, 2-18 parts of purslane and 2-18 parts of mung bean.
Preferably, the medicinal and edible traditional Chinese medicine composition comprises the following raw materials in parts by weight: 25-35 parts of saussurea involucrate culture, 25-35 parts of coix seed, 5-15 parts of purslane and 5-15 parts of mung bean.
Further preferably, the medicinal and edible traditional Chinese medicine composition comprises the following raw materials in parts by weight: 30 parts of saussurea involucrate culture, 30 parts of coix seed, 10 parts of purslane and 10 parts of mung bean.
Further preferably, the medicinal and edible traditional Chinese medicine composition comprises the following raw materials in parts by weight: 25 parts of saussurea involucrate culture, 25 parts of coix seed, 5 parts of purslane and 5 parts of mung bean.
Further preferably, the medicinal and edible traditional Chinese medicine composition comprises the following raw materials in parts by weight: 35 parts of saussurea involucrate culture, 35 parts of coix seed, 15 parts of purslane and 15 parts of mung bean.
The preparation method of the medicinal and edible traditional Chinese medicine composition comprises the following steps:
s1, cleaning a saussurea involucrate culture, coix seeds, purslane and mung beans, drying in the air, crushing, and uniformly mixing to prepare mixed powder;
s2, adding an extracting agent into the mixed powder, uniformly stirring, heating for extraction, centrifuging, and obtaining an extracting solution A and a residue A;
s3, adding an extracting agent into the solid residue obtained in the step S2, stirring, heating for purification, and repeatedly extracting for 3 times to obtain an extracting solution B;
s4, mixing the extracting solution A and the extracting solution B, heating, and concentrating under reduced pressure to obtain a concentrated extract;
s5, preparing the concentrated extract into pills, and drying at 55-65 ℃ to obtain the medicinal and edible traditional Chinese medicine composition.
The heating purification in the step S2 and the step S3 is heating to 40-60 ℃ for purification for 3 h.
The extractant in the step S2 is methanol; the weight part ratio of the extractant to the aired traditional Chinese medicine is 1: 3 to 1: 10; the extractant in the step S3 is methanol; the weight part ratio of the extractant to the residue A is 1: 3 to 1: 10.
the heating in the step S4 is heating to 60 ℃; the reduced pressure concentration is carried out until the weight part ratio of concentrated extract to the dried traditional Chinese medicine is 1: 10.
the raw material components of the invention have the following effects and functions:
saussurea involucrate culture: contains flavone, polysaccharide, chlorogenic acid and other components, and has the following functions: has effects in dispelling cold, supporting yang, regulating menstruation, and stopping bleeding, and can be used for treating sexual impotence, weakness of waist and knees, menoxenia, metrorrhagia, leukorrhagia, rheumatic arthritis, and traumatic hemorrhage.
The coix seeds have the characteristics of sweet and light flavor and cool property; spleen, stomach and lung meridians entered; the function is as follows: induce diuresis, drain dampness, invigorate spleen, check diarrhea, remove arthralgia, expel pus, remove toxicity and dissipate nodulation. Can be used for treating edema, loempe, dysuresia, spleen deficiency, diarrhea, damp arthralgia, spasm, pulmonary abscess, and intestinal abscess; wart, cancerous protuberance.
Purslane: the nature and taste are sour and the nature is cold. The function is as follows: clearing away heat and toxic material, cooling blood and stopping bleeding. Can be used for treating dysentery with bloody pus, stranguria with heat, leukorrhagia, carbuncle, swelling, sore, and erysipelas.
Mung bean: sweet in nature and taste, cold in nature. The function is as follows: has effects in removing summer-heat, promoting diuresis, and clearing away heat and toxic materials. Can be used for treating swelling and pain of pyocutaneous disease due to heat toxin, and preventing measles; it excels in relieving heat toxicity, and is a good antidotal drug for intoxication and food poisoning caused by strong pungent and heat-toxic herbs such as Fu Zi and croton seed; can clear away summer heat, and can prevent heatstroke by boiling mung bean soup in summer; can be used for treating difficult urination and dribbling urination.
The invention has the beneficial effects that:
(1) the medicinal and edible traditional Chinese medicine composition provided by the invention adopts pure natural raw materials, does not contain additives, has no side effect, can be eaten for a long time, can effectively improve and regulate damp-heat constitution, and has obvious effects on common diseases of patients with damp-heat constitution, such as spleen and stomach damp-heat, liver and gallbladder damp-heat, bladder damp-heat, intestinal tract damp-heat and the like.
(2) The preparation method of the medicinal and edible traditional Chinese medicine composition provided by the invention is simple to operate, and can fully release the active ingredients in the raw material medicines while retaining the active ingredients of the raw material medicines to the maximum extent, so that the finally prepared traditional Chinese medicine composition has good medicinal effect and is easy to absorb.
Detailed Description
Hereinafter, embodiments of the present invention will be described in detail. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
It is to be noted that, unless otherwise specified, technical or scientific terms used herein shall have the ordinary meaning as understood by those skilled in the art to which the invention pertains.
Example 1
A medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution comprises the following raw material components in parts by weight: 30 parts of saussurea involucrate culture, 30 parts of coix seed, 10 parts of purslane and 10 parts of mung bean.
The preparation method of the medicinal and edible traditional Chinese medicine composition comprises the following steps:
s1, cleaning a saussurea involucrate culture, coix seeds, purslane and mung beans, drying in the air, crushing, and uniformly mixing to prepare mixed powder;
s2, adding an extracting agent into the mixed powder, uniformly stirring, heating for extraction, centrifuging, and obtaining an extracting solution A and a residue A;
s3, adding an extracting agent into the solid residue obtained in the step S2, stirring, heating for purification, and repeatedly extracting for 3 times to obtain an extracting solution B;
s4, mixing the extracting solution A and the extracting solution B, heating, and concentrating under reduced pressure to obtain a concentrated extract;
s5, preparing the concentrated extract into pills, and drying at 55-65 ℃ to prepare the pills.
The heating purification in the step S2 and the step S3 is heating to 40-60 ℃ for purification for 3 h.
The extractant in the step S2 is methanol; the weight part ratio of the extractant to the aired traditional Chinese medicine is 1: 5; the extractant in the step S3 is methanol; the weight part ratio of the extractant to the residue A is 1: 5.
the heating in the step S4 is heating to 60 ℃; the reduced pressure concentration is carried out until the weight part ratio of concentrated extract to the dried traditional Chinese medicine is 1: 10.
example 2
A medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution comprises the following raw material components in parts by weight: 25 parts of saussurea involucrate culture, 25 parts of coix seed, 5 parts of purslane and 5 parts of mung bean.
The preparation method of the medicinal and edible traditional Chinese medicine composition comprises the following steps:
s1, cleaning a saussurea involucrate culture, coix seeds, purslane and mung beans, drying in the air, crushing, and uniformly mixing to prepare mixed powder;
s2, adding an extracting agent into the mixed powder, uniformly stirring, heating for extraction, centrifuging, and obtaining an extracting solution A and a residue A;
s3, adding an extracting agent into the solid residue obtained in the step S2, stirring, heating for purification, and repeatedly extracting for 3 times to obtain an extracting solution B;
s4, mixing the extracting solution A and the extracting solution B, heating, and concentrating under reduced pressure to obtain a concentrated extract;
s5, preparing the concentrated extract into pills, and drying at 55-65 ℃ to obtain the medicinal and edible traditional Chinese medicine composition.
The heating purification in the step S2 and the step S3 is heating to 40-60 ℃ for purification for 3 h.
The extractant in the step S2 is methanol; the weight part ratio of the extractant to the aired traditional Chinese medicine is 1: 5; the extractant in the step S3 is methanol; the weight part ratio of the extractant to the residue A is 1: 5.
the heating in the step S4 is heating to 60 ℃; the reduced pressure concentration is carried out until the weight part ratio of concentrated extract to the dried traditional Chinese medicine is 1: 10.
example 3
A medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution comprises the following raw material components in parts by weight: 35 parts of saussurea involucrate culture, 35 parts of coix seed, 15 parts of purslane and 15 parts of mung bean.
The preparation method of the medicinal and edible traditional Chinese medicine composition comprises the following steps:
s1, cleaning a saussurea involucrate culture, coix seeds, purslane and mung beans, drying in the air, crushing, and uniformly mixing to prepare mixed powder;
s2, adding an extracting agent into the mixed powder, uniformly stirring, heating for extraction, centrifuging, and obtaining an extracting solution A and a residue A;
s3, adding an extracting agent into the solid residue obtained in the step S2, stirring, heating for purification, and repeatedly extracting for 3 times to obtain an extracting solution B;
s4, mixing the extracting solution A and the extracting solution B, heating, and concentrating under reduced pressure to obtain a concentrated extract;
s5, preparing the concentrated extract into pills, and drying at 55-65 ℃ to obtain the medicinal and edible traditional Chinese medicine composition.
The heating purification in the step S2 and the step S3 is heating to 40-60 ℃ for purification for 3 h.
The extractant in the step S2 is methanol; the weight part ratio of the extractant to the aired traditional Chinese medicine is 1: 5; the extractant in the step S3 is methanol; the weight part ratio of the extractant to the residue A is 1: 5.
the heating in the step S4 is heating to 60 ℃; the reduced pressure concentration is carried out until the weight part ratio of concentrated extract to the dried traditional Chinese medicine is 1: 10.
test examples
The medicine-food homologous traditional Chinese medicine composition for conditioning damp-heat physique in embodiment 1 of the invention has the following analysis on use effect:
the using method comprises the following steps: it is taken with warm water 2 times daily, 1 pill each time, 1g each pill.
Local damp-heat physique patients are selected for clinical observation, and the results are shown in table 1:
table 1:
therapeutic effect Dampness-heat in the spleen and stomach Damp-heat in the liver and gallbladder Damp-heat in the large intestine
Recovery method 23 22 23
Show effect 1 2 0
Improvement of life 1 1 2
Invalidation 0 0 0
Total effective rate 100% 100% 100%
Average number of days required for patients with disease 150 150 150
Case 1:
jiangzhi, male, 34 years old, damp-heat in the spleen and stomach, abdominal distension, nausea, anorexia, loose stool. By using the medicinal and edible traditional Chinese medicine composition for treating damp-heat in the embodiment 1 of the invention for 5 months, symptoms disappear, and after the composition is continuously taken for one year, the body constitution is mild without relapse.
Case 2:
wangzhi, female, 42 years old, often with abdominal pain and diarrhea, burning anus, thirst, yellow and greasy tongue coating. By using the medicinal and edible traditional Chinese medicine composition for treating damp-heat in the embodiment 1 of the invention for 5 months, symptoms disappear, and after the composition is continuously taken for one year, the body constitution is mild without relapse.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.

Claims (9)

1. A medicine-food homologous traditional Chinese medicine composition for conditioning damp-heat constitution is characterized in that: the medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 20-40 parts of saussurea involucrate culture, 20-40 parts of coix seed, 2-18 parts of purslane and 2-18 parts of mung bean.
2. The medicinal and edible traditional Chinese medicine composition as claimed in claim 1, which is characterized in that: the medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 25-35 parts of saussurea involucrate culture, 25-35 parts of coix seed, 5-15 parts of purslane and 5-15 parts of mung bean.
3. The medicinal and edible traditional Chinese medicine composition as claimed in claim 2, which is characterized in that: the medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 30 parts of saussurea involucrate culture, 30 parts of coix seed, 10 parts of purslane and 10 parts of mung bean.
4. The medicinal and edible traditional Chinese medicine composition as claimed in claim 2, which is characterized in that: the medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 25 parts of saussurea involucrate culture, 25 parts of coix seed, 5 parts of purslane and 5 parts of mung bean.
5. The medicinal and edible traditional Chinese medicine composition as claimed in claim 2, which is characterized in that: the medicinal and edible traditional Chinese medicine composition comprises the following raw material components in parts by weight: 35 parts of saussurea involucrate culture, 35 parts of coix seed, 15 parts of purslane and 15 parts of mung bean.
6. The preparation method of the medicinal and edible traditional Chinese medicine composition as claimed in any one of claims 1 to 5, which is characterized in that: the preparation method comprises the following steps: s1, cleaning a saussurea involucrate culture, coix seeds, purslane and mung beans, drying in the air, crushing, and uniformly mixing to prepare mixed powder; s2, adding an extracting agent into the mixed powder, uniformly stirring, heating for extraction, centrifuging, and obtaining an extracting solution A and a residue A; s3, adding an extracting agent into the solid residue obtained in the step S2, stirring, heating for purification, and repeatedly extracting for 3 times to obtain an extracting solution B; s4, mixing the extracting solution A and the extracting solution B, heating, and concentrating under reduced pressure to obtain a concentrated extract; s5, preparing the concentrated extract into pills, and drying at 55-65 ℃ to obtain the medicinal and edible traditional Chinese medicine composition.
7. The method of claim 6, wherein: the heating purification in the step S2 and the step S3 is heating to 40-60 ℃ for purification for 3 h.
8. The method of claim 6, wherein: the extractant in the step S2 is methanol; the weight part ratio of the extractant to the aired traditional Chinese medicine is 1: 3 to 1: 10; the extractant in the step S3 is methanol; the weight part ratio of the extractant to the residue A is 1: 3 to 1: 10.
9. the method of claim 6, wherein: the heating in the step S4 is heating to 60 ℃; the reduced pressure concentration is carried out until the weight part ratio of concentrated extract to the dried traditional Chinese medicine is 1: 10.
CN202010675563.6A 2020-07-14 2020-07-14 Medicinal and edible traditional Chinese medicine composition for conditioning damp-heat constitution and preparation method thereof Pending CN111773337A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104095108A (en) * 2014-06-04 2014-10-15 胡安然 Tea capable of conditioning damp-heat constitution
CN109090596A (en) * 2018-09-17 2018-12-28 宣城华科宣木瓜生物科技有限公司 A kind of Xuancheng's pawpaw paste and preparation method thereof improving damp-heat constitution
CN111184176A (en) * 2018-11-15 2020-05-22 天津红日丽康生物科技有限公司 Instant health food composition for nine different constitutions based on theory of constitutions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104095108A (en) * 2014-06-04 2014-10-15 胡安然 Tea capable of conditioning damp-heat constitution
CN109090596A (en) * 2018-09-17 2018-12-28 宣城华科宣木瓜生物科技有限公司 A kind of Xuancheng's pawpaw paste and preparation method thereof improving damp-heat constitution
CN111184176A (en) * 2018-11-15 2020-05-22 天津红日丽康生物科技有限公司 Instant health food composition for nine different constitutions based on theory of constitutions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
孟昭泉等: "《五色食物药膳食疗方》", 31 July 2015, 金盾出版社 *
钟赣生等: "《中药学》", 31 August 2016, 中国中医药出版社 *

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