CN117618524A - Mongolian navel patch for treating digestive system diseases - Google Patents
Mongolian navel patch for treating digestive system diseases Download PDFInfo
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- CN117618524A CN117618524A CN202210977264.7A CN202210977264A CN117618524A CN 117618524 A CN117618524 A CN 117618524A CN 202210977264 A CN202210977264 A CN 202210977264A CN 117618524 A CN117618524 A CN 117618524A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention discloses a Mongolian navel patch for treating digestive system diseases, which comprises the following components in parts by weight: main medicine: 50-100 parts of pomegranate, 20-50 parts of cinnamon, 20-50 parts of fructus alpiniae oxyphyllae and 20-50 parts of fructus tsaoko; adjuvant drug: 15-30 parts of dried ginger, 10-30 parts of long pepper, 20-50 parts of costustoot and 5-10 parts of safflower; adjuvant drug: 10-30 parts of black grass seeds, 10-20 parts of table salt, 1-2 parts of sal ammoniac, 10-30 parts of white pepper and 10-30 parts of white jusheng; the preparation method comprises the following steps: 15-30 parts of coriander fruits, 20-50 parts of clove, 20-30 parts of liquorice, and 10-20 parts of camphor. The Mongolian medicine navel patch has better clinical curative effect on treating infantile cold diarrhea, can obviously improve clinical symptoms and physical signs of children suffering from cold diarrhea, and has better curative effect on improving inappetence.
Description
Technical field:
the invention relates to the field of medicines, in particular to a Mongolian navel patch for treating digestive system diseases.
The background technology is as follows:
the Mongolian medicine considers that children have different characteristics of adults in physiological and pathological aspects. Physiological aspects are the dry constitution of the Badado, tender viscera, immature constitution, vigorous physiology, rapid development and the like. The disease is easy to occur, the change is rapid, the disease resistance is poor, the convulsion is easy to occur after high fever, the symptoms cannot be stated, the examination is not matched, and the like, and simultaneously, the diagnosis is difficult, the cure is easy to be carried out once the diagnosis is confirmed, the cure is rapid, and the like. The infant is just like the sprout of the sprout, and the morphological structure and physiological function of each organ of the body are immature and immature. The qi of the five zang-organs and six fu-organs is relatively deficient, and the three zang-organs, i.e. the lung, spleen and kidney, are the most prominent. The digestive system is tender, various digestive enzymes in the body are less secreted and have low vitality, the body has poor tolerance to food, if the body is fed improperly or the abdomen is cooled and the disease state is caused, the digestive function disorder can be caused, and the symptoms such as dyspepsia diarrhea, inappetence, abdominal pain, borborygmus and the like can be easily caused.
The external treatment method of the Mongolian medicine refers to the external treatment method that the Mongolian medicine preparation of different types is acted on the human body through the body surface or the sense orifice by taking the Mongolian medicine basic theory as the guidance so as to obtain the local or systemic effect; has the characteristics and advantages of quick curative effect, small side effect, simple and convenient operation, long-term application and the like. The children are of small age, especially the infants and infants are difficult to feed medicine, and the children have the characteristics of urgent onset of diseases, rapid change of illness and the like, and the external treatment method is timely applied to obtain satisfactory curative effects. Because children are in continuous growth and development, the external therapy has great advantages because of the characteristics of physiology and pathology. External therapies developed in the prior art include bleeding therapy, puncture therapy, cataplasm therapy, moxibustion therapy, embrocation therapy, birthday therapy, and patch therapy.
The application therapy is a Mongolian external therapy method, can treat internal diseases externally, can condition viscera functions, is a therapy combining Mongolian medicines, butter and hot compress, has good curative effect on digestive system diseases, is one of common traditional therapies, and is a diagnosis and treatment method with quick and safe effect on treating the digestive system diseases of children. The application therapy has very wide application, and common diseases and frequently encountered diseases can be treated by the method. The patch therapy is Mongolian medicine for treating digestive system diseases, and causes abdominal pain, diarrhea, and emesis. If the body temperature is not high, the medicine can be treated by applying a therapy, is also easy to accept by children, and generally adopts stomach warming medicines as main medicines. For symptoms due to spleen yang deficiency, such as abdominal distention and inappetence, the application therapy can be used for improving symptoms. The blue glass is described in: "the children live and grow by breast feeding and are bedridden for a long time, thus being a person with the characteristics of being bardado", the children have relatively blunt stomach fire, but the nutrition substances needed by growth and development are larger. Especially children with the age of less than full year can grow rapidly, and three digestive organs (He Yi, hila, and Badagan) and stomach and intestine have undeveloped functions and are sensitive to cold and heat stimulus, so that the children are prone to dyspepsia and nutritional deficiency. And digestive heat decay with food undigested with abdominal distension, dyspepsia, abdominal pain, borborygmus, emesis, or diarrhea as symptoms. The food which is heavy and greasy and cool and is not easy to digest is taken for a long time, the back and the sole are subjected to cold, a humid environment is kept for a long time, and the food is not digested, and is caused by predominance of Badamgan hertz, decay of stomach fire and digestive dysfunction. For treating the disease, the medicine is orally taken with the principles of dispelling the dry bardado, the herceptin, helping the stomach fire and promoting digestion, namely, the medicine is orally taken with the Anali-4 medicine powder, the Tonga-5 medicine or the four medicine Guangming salt soup. Abdominal cooling, abdominal pain and oral administration of six-ingredient banksia rose powder; the thirteen-ingredient pomegranate powder is taken with cream and brown sugar warm boiled water, the infant is weak, the day round pill is fried, the breast-feeding infant suffers from illness, and the mother and the child can be simultaneously taken for treatment. If diarrhea is frequent, the food intake is temporarily reduced to relieve the burden of digestive organs. The existing method for treating the children digestive system diseases by external treatment of Mongolian medicine mainly comprises the steps of stomach heat fomentation, navel hot compress by using a cream cloth pad or stir-baked salt, sisal process and twelfth vertebral joint point Shi Wenjiu process are adopted, abdomen oil is applied, massage is carried out from top to bottom, recently, anari-4 is added with butter for stirring, a layer of thin gauze is placed at the navel part, 1.5 parts to 3 parts of medicine is taken, the navel part is placed at the navel part, and cold diarrhea of children is treated by baking the abdomen navel part by baking a lamp. Although the Mongolian medical application therapy can be used for the pediatric diseases, the Mongolian medical application therapy still uses an oral preparation to directly crush and use the oral preparation for the pediatric umbilical region at present, and the Mongolian medical application therapy has no special prescription and research on the curative effect, is not simple to use and cannot be directly applied to our lives and the like.
Because of the physiological particularities of children, the search for therapeutic drugs and methods with less toxic and side effects and satisfactory curative effects is currently the most urgent need. The navel is finally closed after the birth of the infant, so that the navel skin barrier function is relatively weak and the periumbilical blood vessels are rich in human bodies, the navel administration is easier to be absorbed by human bodies, and the medicament effect can be exerted to a greater extent by the navel application mode during the clinical treatment of the digestive diseases of the infant, and is more ideal than the oral administration effect. The Mongolian medicine navel patch further optimizes the prescription medicine and the application preparation on the basis of the original Mongolian medicine application therapy, more effectively utilizes the double effects of local absorption of the medicine, and simultaneously avoids toxic and side effects of the medicine because the Mongolian medicine navel patch does not pass through gastrointestinal absorption, does not need to pass through intestinal and liver metabolism. The Mongolian medicine is from nature, has relatively small toxic and side effects, and can reduce the characteristics and advantages of small toxic and side effects, simple and convenient operation, quick response and the like when being used for treating the infantile diseases by using the Mongolian medicine to prepare the navel patch.
The invention comprises the following steps:
for the above reasons, a first object of the present invention is to provide a Mongolian navel patch for treating digestive system diseases.
The second object of the present invention is to provide a method for preparing a Mongolian navel patch for treating digestive system diseases.
The first object of the invention is implemented by the following technical scheme: a Mongolian navel patch for treating digestive system diseases comprises the following components in parts by weight: 50-100 parts of pomegranate, 20-50 parts of cinnamon, 20-50 parts of fructus alpiniae oxyphyllae, 10-30 parts of fructus piperis longi, 10-30 parts of white pepper, 10-20 parts of table salt, 1-2 parts of sal ammoniac, 20-50 parts of fructus tsaoko, 5-10 parts of safflower, 10-30 parts of black seed grass, 10-30 parts of cynomorium songaricum, 20-30 parts of myrobalan, 15-30 parts of dried ginger, 15-30 parts of coriander fruit, 20-50 parts of clove, 20-50 parts of costustoot, 20-30 parts of liquorice and 10-20 parts of camphor.
The second object of the invention is achieved by the following scheme: a preparation method of Mongolian navel patch for treating digestive system diseases comprises the following steps:
s1, preparing raw materials: pomegranate, cinnamon, sharpleaf galangal fruit, long pepper, white pepper, table salt, sal ammoniac, tsaoko cardamon, safflower, black seed grass seed, bai Ju peptide, myrobalan, dried ginger, coriander fruit, clove, costustoot and liquorice, cleaning, airing, powdering and deslagging by a 100-mesh screen; grinding Borneolum Syntheticum and Camphora at low speed to obtain powder, and filtering with 100 mesh sieve to obtain residue;
s2, preparing an umbilical paste: placing all the powder medicines into a stirrer to be uniformly stirred, and preparing into cakes with the diameter of 1.5-3cm and the thickness of 0.3-1cm by using butter every 1.5-3.0 g; obtaining the navel patch.
Preferably, the diameter of the medicine cake is 2cm, and the thickness is 0.5cm.
The nature, taste and function of the medicinal components
1. And (3) pomegranate: sour, sweet, warm, sharp, coarse, greasy, dry and light. Has stomach fire promoting, and digestion promoting effects. Is mainly used for treating dyspepsia, dry bardado, nausea, emesis, large intestine diarrhea, abdominal distention, belch, etc.
2. Cinnamon: sweet, spicy, salty, hot, greasy, light, dry, sharp. Has effects in dispelling cold, regulating fire, relieving diarrhea, and expelling pus. Is mainly used for treating gastralgia, dry stomach, cold diarrhea, lung abscess and the like.
3. Developing intelligence: pungent taste, warm nature, greasy, sharp, light and dry. Has effects of dispelling kidney cold, relieving hertz, regulating fire, promoting digestion, stimulating appetite, and relieving vomiting. Is mainly used for treating symptoms such as stomach fire decay, dyspepsia, antiemetic, appetite stimulating, kidney-cold and heart-cold type hery.
4. Fructus Piperis Longi: pungent taste, warm nature, greasy, sharp, light and dry. Has effects in promoting stomach fire, dispelling badamgan Heryi, regulating body constitution, supporting yang, relieving asthma, eliminating phlegm, and relieving pain. Is mainly used for treating the badamgan heryi complications, dyspepsia, nausea, cold vomiting and diarrhea, lumbago and skelalgia, kidney cold, asthma and cough, insomnia and the like.
5. White pepper: extremely pungent in flavor, warm, light, dry, rough, sharp and dynamic. Has effects of promoting stomach fire, resolving food stagnation, stimulating appetite, and removing badamgan Heryi. Is mainly used for treating diseases such as the badamgan heryi, dyspepsia, gastralgia, cold diarrhea, skin pain and itch and the like.
6. Photopic salt: sweet, salty, warm, sharp, heavy and soft. Has stomach fire promoting, digestion promoting, and badafuyi dispelling effects. Mainly treats dyspepsia, and diseases such as gastrectasia, retching, diarrhea, herceptin headache and the like.
7. Cyanide of sal ammoniac: salty and pungent taste, warm nature, heavy and greasy. Has effects of invigorating stomach fire, suppressing the excessive heat of the body, relieving constipation, stopping sunstroke, and relieving stinging. Mainly treats the diseases of the badamch-dependent abdominal distention, dyspepsia, constipation, cold-therapy, gastralgia, herynia and the like.
8. Fructus Tsaoko: pungent taste, warm nature, dryness, roughness and light weight. Has effects in dispelling cold of stomach and spleen, promoting digestion, and invigorating stomach fire. Mainly treats spleen dry barda, dyspepsia, cold vomiting and diarrhea, gastric hertz, abdominal distention, hertz headache and the like.
9. Safflower: sweet and slightly bitter in flavor, cool in nature, blunt, soft, mild, heavy and firm. Has effects in invigorating pulse, regulating menstruation, clearing away liver heat, tonifying, strengthening body constitution, relieving pain, and relieving swelling. Is used for treating liver heat, blood heat, menoxenia, liver diseases, digestive tract hemorrhage, epistaxis, dystocia, traumatic hemorrhage, blood heat headache, heart heat, etc.
10. Black grass seed: sweet and pungent in flavor, warm in nature, light in weight, sharp in nature and dry in nature. Has effects in regulating stomach fire, promoting digestion, and moistening teeth. Is mainly used for treating dyspepsia, liver pain, liver cold and abdominal distention, etc.
11. White huge winning: slightly pungent in flavor, mild in nature, light, sharp, dull and dry. Has effects in clearing lung-heat, relieving hertz, promoting digestion, and stimulating appetite. Mainly treats dyspepsia, nausea, sleep aiding, cough, phlegm cough, and the like.
12. Myrobalan: sour, astringent, bitter and neutral in nature. Has the functions of eliminating pathogenic factor, detoxication, regulating three functions of Chinese medicinal materials and stopping diarrhea. Is used for treating Herie disease, hila disease, dry bar disease, polydisease, complications, poisoning, diarrhea, trauma, and relieving drug toxicity and intensity.
13. Dried ginger: pungent, sweet, warm, rough, dull, dry and dynamic. Has effects in promoting stomach fire, resolving food stagnation, stimulating appetite, and regulating functions of radix Et rhizoma Rhei. Mainly treats the diseases of the badamgan heryi disease, dyspepsia, nausea, turbid sperm and the like.
14. Coriander fruit: pungent taste, sour taste, cool nature, coarse, light, thin and greasy. Has effects of relieving dry heat, promoting digestion, stimulating appetite, quenching thirst, and promoting eruption. It is used for treating inappetence, dyspepsia, acid regurgitation, heart burn, abdominal pain, rash, and thirst.
15. Clove: pungent, slightly bitter, warm, heavy, soft, greasy, stable and dry. Has cold dispelling effect. Helping stomach fire, helping digestion, stimulating appetite, removing toxin, relieving exterior rash and relieving sore throat. It is mainly used for treating the diseases of the Heyi disease, the rash, the pharyngeal plug and the like of the fortune pulse.
16. Radix aucklandiae: pungent and bitter taste, warm nature, greasy, coarse and light. Has effects in clearing heat, calming qi and blood, relieving distention and fullness, expelling pus, eliminating phlegm, preventing corrosion, and relieving pain. Mainly treats diseases such as qi and blood phase pulsation, diseases such as stomach ache, belch, vomit, stomach disease, hila chest stuffiness, blood chest stuffiness, short breath, phlegm reduction, heryi and the like.
17. Licorice root: sweet in taste, cool, thin, soft, mild and light in weight. Has the effects of invigorating spleen, replenishing qi, clearing heat, detoxicating, eliminating phlegm, relieving cough, relieving spasm, relieving pain and harmonizing various medicines. It is indicated for weakness of spleen and stomach, lassitude, palpitation, shortness of breath, cough with excessive phlegm, abdominal pain, limb spasm, pain, carbuncle, swelling and sore, and toxicity, and is used for relieving drug toxicity and intensity.
18. Camphor: pungent and warm in nature. Has effects of dredging orifices, activating stagnated qi, removing turbid urine, killing parasites, relieving itching, and relieving swelling and pain. Is used for treating fever, unconsciousness, sudden collapse, diarrhea, abdominal pain, cold dampness, tinea pedis, scabies, tinea, chilblain, ecthyma, scald, traumatic injury, toothache, wind-fire conjunctival congestion, and conjunctival congestion.
The invention has the advantages that:
1. in the prescription, myrobalan, pomegranate, fructus alpiniae oxyphyllae, cinnamon and fructus tsaoko are taken as main medicines, and the effects of assisting stomach fire, dispelling bardado without inducing liver heat, zhenhei, helping digestion, stimulating appetite, relieving diarrhea, relieving pain and the like are taken as main medicines, so that the prescription is mainly used for treating the children digestive system diseases, the first medicine in the prescription is an indispensable medicine in the prescription, wherein the myrobalan: sour, astringent, bitter and neutral in nature. Has the functions of eliminating pathogenic factor, detoxication, regulating three voxels and stopping diarrhea. Is used for treating Herie disease, hila disease, dry bar disease, polydisease, complications, poisoning, diarrhea, trauma, and relieving drug toxicity and intensity. Pharmacological experiments prove that the myrobalan decoction is effective in removing dysentery bacillus, and has inhibition effect on pseudomonas aeruginosa, pneumococcus, hemolytic streptococcus, proteus and typhimurium. The myrobalan extract has fire extinguishing effect on influenza. The chebulin extracted from ethanol has papaverine-like spasmolytic effect on smooth muscle. It also has astringent and antidiarrheal effects. Has insect repellent effect; and (3) pomegranate: sour, sweet, warm, sharp, coarse, greasy, dry and light, has the functions of helping stomach fire, dispelling herceptin dry, helping digestion, stimulating appetite and stopping diarrhea. Mainly treats dyspepsia, dry disease of the baddar, nausea and vomiting, large intestine heryi, cold diarrhea, abdominal distension, belching and other symptoms, and modern medicine considers that the pomegranate has an inhibiting effect on bacillus dysenteriae and dermatophytes, has obvious curative effects in clinic for treating acute dysentery and amoebic dysentery; the good medicine for improving intelligence and treating kidney diseases has the functions of dispelling kidney cold, relieving hertz, regulating fire, promoting digestion, stimulating appetite and stopping vomiting, and is mainly used for treating symptoms such as stomach fire decay, dyspepsia, antivomiting, stimulating appetite, dispelling kidney, heart cold and the like; cinnamon is sweet, spicy, salty, hot, greasy, light, dry and sharp, has the functions of dispelling cold and herding, regulating fire, relieving diarrhea, expelling pus, mainly treats symptoms such as gastralgia, dry stomach, cold diarrhea, lung abscess and the like, and modern researches show that the cinnamon pharmacological component can inhibit gastric secretion and pepsin activity, can obviously increase bile secretion, has excitation effect on intestinal activity, and has the effects of resisting ulcer, calming and easing pain, resisting bacteria and diminishing inflammation, and regulating body temperature; fructus Tsaoko is a good herb for treating spleen diseases, has pungent taste, warm nature, dryness, roughness and light weight. Has effects in dispelling cold of stomach and spleen, promoting digestion, and invigorating stomach fire. Mainly treats spleen barda dryness, dyspepsia, cold vomiting and diarrhea, stomach hertz, abdominal distention, hertz headache and other symptoms;
2. in the formula, the dried ginger, the long pepper, the costustoot and the safflower are taken as auxiliary medicines, and the dried ginger is one of three hot medicines, and has the characteristics of pungent taste, sweet taste, mild nature, coarse taste, dullness, dryness and movement. Has effects in promoting stomach fire, resolving food stagnation, stimulating appetite, and regulating functions of radix Et rhizoma Rhei. Mainly treats the diseases of the badamgan heryi disease, dyspepsia, nausea, turbid sperm and the like. Pharmacological experiments prove that the dried ginger has slight stimulation to the digestive tract, and can promote the increase of intestinal tension, rhythm and peristalsis. The extract can inhibit emesis of dog caused by copper sulfate. Clinically used for treating gastrointestinal pain, angina, rheumatalgia, lumbago, skelalgia, gastric and duodenal ulcer, acute bacillary dysentery, ascariasis intestinal obstruction, chronic dyspepsia and other symptoms; fructus Piperis Longi is one of the three Mongolian medicines, and has pungent taste, warm nature, greasy, sharp, light and dry nature. Has effects in invigorating stomach fire, dispelling pathogenic fire, regulating body constitution, supporting yang, relieving asthma, eliminating phlegm, and relieving pain, and can be used for treating diseases due to complications of nodakenin, dyspepsia, nausea, emesis, diarrhea, lumbago, skelalgia, kidney cold, cough, insomnia, etc. Pharmacological experiments prove that the essential oil extracted from the long pepper has antibacterial effects on staphylococcus aureus, bacillus subtilis, bacillus cereus, tubercle bacillus, bacillus dysenteriae, typhoid bacillus butyl, B-vitelline sarcina and the like; the smell of wood is pungent and bitter, warm in nature, greasy, coarse and light. Has effects in clearing heat, calming qi and blood, relieving distention and fullness, expelling pus, eliminating phlegm, preventing corrosion, and relieving pain. Mainly treats diseases such as qi and blood phase pulsation, diseases such as stomach ache, belch, vomit, stomach disease, hila chest stuffiness, blood chest stuffiness, short breath, phlegm reduction, heryi and the like. Pharmacological experiments prove that the costustoot alkaloid has the effects of inhibiting vagus nerves and central nerves and has obvious spasmolytic effect on the spasm of the smooth muscle of the trachea and the small intestine caused by histamine; safflower is a good herb for treating liver diseases, and has sweet and slightly bitter taste, cool, dull, soft, mild, heavy and firm nature. Has effects in invigorating pulse, regulating menstruation, clearing away liver heat, tonifying, strengthening body constitution, relieving pain, and relieving swelling. The safflower is mainly used for treating liver heat, blood heat, irregular menstruation, liver diseases such as illness, alimentary canal hemorrhage, epistaxis, dystocia, traumatic hemorrhage, blood heat headache, heart heat and other diseases, and modern researches consider that the safflower has the effects of improving blood circulation, reducing blood pressure and blood lipid, resisting blood coagulation and relieving pain strongly and durably;
3. the formula takes black seed grass seeds, photoplethysmogram, sal ammoniac, white pepper and Bai Jusheng as adjuvant drugs, and the black seed grass seeds: sweet and pungent in flavor, warm in nature, light in weight, sharp in nature and dry in nature. Has effects in regulating stomach fire, promoting digestion, and moistening teeth. Is mainly used for treating dyspepsia, liver pain, liver cold and abdominal distention, etc. Photopic salt: sweet, salty, warm, sharp, heavy and soft. Has effects in promoting stomach fire, resolving food stagnation, and removing badamgan heryi, and can be used for treating dyspepsia, such as gastrectasia, retching, diarrhea, herception headache, etc. Pharmacological experiments prove that the traditional Chinese medicine composition can slightly stimulate gastrointestinal mucosa of a patient, promote secretion of gastrointestinal fluid, and enhance gastrointestinal absorption and peristaltic ability; zhenhei is a common herb of cyanide with salty and pungent taste, warm nature, heavy and greasy taste. Has effects of invigorating stomach fire, suppressing the excessive heat of the body, relieving constipation, stopping sunstroke, and relieving stinging. Mainly treats the diseases of the badamch-dependent abdominal distention, dyspepsia, constipation, cold-therapy, gastralgia, herynia and the like. The drug experiments prove that the sal ammoniac has obvious inhibiting effect on sarcoma; white pepper: extremely pungent in flavor, warm, light, dry, rough, sharp and dynamic. Has effects of promoting stomach fire, resolving food stagnation, stimulating appetite, and removing badamgan Heryi. Is mainly used for treating diseases such as the badamgan heryi, dyspepsia, gastralgia, cold diarrhea, skin pain and itch and the like. Pharmacological experiments prove that the piperine has antidepressant, sedative and insecticidal effects; white huge winning: slightly pungent in flavor, mild in nature, light, sharp, dull and dry. Has effects in clearing lung-heat, relieving hertz, promoting digestion, and stimulating appetite. Mainly treats dyspepsia, nausea, sleep aiding, cough, phlegm cough, and the like.
The recipe uses coriander fruit, licorice, clove and camphor as guiding drugs, and licorice has sweet taste, cool, thin, soft, mild and light nature. Has the effects of invigorating spleen, replenishing qi, clearing heat, detoxicating, eliminating phlegm, relieving cough, relieving spasm, relieving pain and harmonizing various medicines. It is indicated for weakness of spleen and stomach, lassitude, palpitation, shortness of breath, cough with excessive phlegm, abdominal pain, limb spasm, pain, carbuncle, swelling and sore, and toxicity, and is used for relieving drug toxicity and intensity. Pharmacological experiments prove that the licorice extract can relieve irritation of throat mucous membrane, and relieve gastrointestinal smooth muscle spasm and antiulcer activity. The licorice preparation and glycyrrhizin have effects of relieving cough, eliminating phlegm, tranquilizing, relieving inflammation, resisting bacteria and allergy; ding Xiangwei it is pungent, slightly bitter, warm, heavy, soft, greasy, stable and dry. Has cold dispelling effect. Helping stomach fire, helping digestion, stimulating appetite, removing toxin, relieving exterior rash and relieving sore throat. It is mainly used for treating the diseases of the Heyi disease, the rash, the pharyngeal plug and the like of the fortune pulse. Pharmacological experiments prove that the clove leaching solution has the stomach strengthening effect. The decoction can be used for treating various pathogenic fungi, coccus, streptococcus, pneumonia, dysentery, pseudomonas aeruginosa, and Bacillus and influenza virus PR 8 The plants and the like have antibacterial effect.
The specific embodiment is as follows:
the following description of the embodiments of the present invention will be made clearly and completely, and it is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
A Mongolian medicine navel patch formula mainly used for treating children digestive system diseases, which comprises the following components: 80g of pomegranate, 30g of cinnamon, 30g of alpinia oxyphylla, 20g of long pepper, 20g of white pepper, 15g of table salt, 1-2g of sal ammoniac, 30g of tsaoko cardamon, 5g of safflower, 20g of nigella sativa seed, bai Jusheng g of myrobalan, 20g of dried ginger, 20g of coriander fruit, 30g of clove, 30g of costustoot, 20g of liquorice, 10g of camphor and 10g of borneol.
Example 2
The preparation method of the Mongolian medicine navel patch of Enke jin by using the formula of the embodiment 1 comprises the following specific steps:
the following Mongolian medicinal materials are weighed according to the proportion: pomegranate, cinnamon, sharpleaf galangal fruit, long pepper, white pepper, table salt, sal ammoniac, tsaoko cardamon, safflower, black seed grass seed, bai Ju peptide, myrobalan, dried ginger, coriander fruit, clove, costustoot and liquorice, cleaning, airing, powdering and deslagging by a 100-mesh screen; grinding Borneolum Syntheticum and Camphora at low speed to obtain powder, and filtering with 100 mesh sieve to obtain residue; and (5) placing all the medicines into a stirrer to be stirred uniformly, and sealing and packaging the medicines for use.
Clinical experiments were performed using the navel patch formulation prepared in example 2.
The using method comprises the following steps: the medicinal powder is prepared into thick paste by using a proper amount of butter, and is locally applied to the umbilical region of the infant, wherein the single application time is 12h, and 1 time a day.
All the 64 observed cases which meet the case inclusion criteria and the exclusion criteria (the inclusion criteria and the exclusion criteria are described later) and meet the diagnosis criteria of the infantile cold diarrhea between 1 month in 2019 and 1 month in 2021 are randomly divided into an observation group and a control group, wherein 32 cases of men and women in the group are 38 cases and 26 cases of men and women in the group are 3-12 months 19 cases, 13-24 months 13 cases and 25-36 months 32 cases; 59 cases for 0-7 days, 5 cases for 8-14 days; through statistical analysis, the two groups of children patients have no significant difference (P > 0.05) in gender, age and disease course, and the two groups of data are comparable.
Case inclusion criteria
(1) Meets the diagnosis standard of the pediatric cold diarrhea medical science (see the subsequent description);
(2) Meets the diagnosis standard of cold diarrhea of children in traditional Chinese medicine (see the subsequent description);
(3) Patients with ages between 3 months and 3 years;
(4) No history of allergy
(5) No skin damage, scar, open wound, etc. around umbilicus;
(6) The children with no fever in the course of the disease;
case exclusion criteria
(1) Child patients under 3 months of age or over 3 years of age;
(2) Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system, and infectious dermatoses;
(3) Severely dehydrated infants;
(4) Skin damage, scar, open wound, etc. are around umbilicus;
(5) Skin is particularly sensitive, allergic constitution;
(6) Parents of the child or other legal guardians informed consent.
(7) Child suffering from fever in the course of disease;
mongolian medical diagnosis standard (refer to Mongolian medical disease diagnosis and treatment guide issued by the inner Mongolian autonomous region health hall in 2007)
(1) Dyspepsia, repeated abdominal pain, diarrhea for 3-5 times/day or more than 10 times/day, and some infants with nausea, emesis, thirst and other complications;
(2) The exacerbation of the illness causes diarrhea with increased times, poor spirit, dry skin, poor elasticity and no tears, and even causes serious dehydration symptoms such as confusion;
(3) Infants are more ill, have poor diet collocation or have cold in the abdomen, waist and instep, and are easy to suffer from the disease due to cold and the like;
(4) A weak pulse condition, pale tongue fur and clear urine;
diagnostic criteria for traditional Chinese medicine: the Chinese medicine disease diagnosis curative effect standard is referred to the Chinese people's republic of China.
Diarrhea due to wind-cold: the stool has light color, foam, no obvious odor, abdominal pain and borborygmus. Or with nasal obstruction and nasal discharge, fever. A white and greasy tongue coating and a slippery and powerful pulse.
Diarrhea due to damp-heat: turbid and sticky and turbid urine, difficult and smooth stool, dysentery-like, non-dysentery, a small amount of urine, burning anus, fever or fever, thirst, poor appetite, and abdominal distension. The face Huang Chungong is red with a yellow and thick coating, and the finger is purple with stagnancy and the pulse is frosty and rapid.
Diarrhea due to overeating: the stool is sour and smelly, or such as aborted eggs, distending abdomen, bad breath and anorexia, abdominal pain and crying before diarrhea, and nausea and vomiting are often accompanied. A thick and greasy coating and a slippery and powerful pulse.
Diarrhea due to cold dampness: the stool is thin like water, light yellow and odorless, abdominal distention and borborygmus, light mouth and thirst, light lip and tongue color, poor appetite, or vomiting after eating, scanty urine, yellow and abdominal pain, listlessness and lassitude. A white, thick and greasy coating, a pale finger and a soft pulse.
Spleen deficiency diarrhea syndrome: chronic diarrhea, repeated attacks, thin stool, watery stool, milk valve or indigestible food residue. Lassitude, anorexia, pale complexion, pale tongue with thin and greasy coating, weak pulse.
Spleen-kidney yang deficiency type diarrhea bay: loose stool, incomplete grain, emaciation, or a weak face, a superficial body, and a warm limbs. Pale tongue with white coating and thready and weak pulse.
Treatment regimen
1. The Mongolian medical treatment method comprises the following steps: the observation group prepares 2g of Mongolian medicine navel patch of Envelcade in butter into a medicinal cake with the diameter of 2cm and the thickness of 0.5cm, and the medicinal cake is placed in the center of the infant navel protection patch and applied to the umbilical region.
2. The control group was applied to the umbilical region using the Tinggui navel patch.
3. Both groups were applied 1 day for 1 time and 1 time for 24 hours, both groups were observed for the same time, 1 course of treatment was 3 days, and 2 courses of treatment were observed consecutively.
Results: (1) The two groups of children have no statistical significance (P > 0.05) in terms of gender, age, disease course, illness, symptoms, signs and the like. (2) After 1 treatment course, observing 2 cases of group cure, 8 cases of effective cases, 9 cases of effective cases, 13 cases of ineffective cases, and 59.38% of total effective rate; the control group heals 3 cases, 10 cases with obvious effect, 7 cases with effective effect, 12 cases with ineffective effect, the total effective rate is 62.5%, and the two groups have no difference (P is more than 0.05); after 2 treatment courses, 4 cases of group recovery are observed, 17 cases of effective treatment are performed, 6 cases of effective treatment and 5 cases of ineffective treatment, the total effective rate reaches 84.37%, 5 cases of control group recovery are performed, 16 cases of effective treatment are performed, 7 cases of effective treatment and 4 cases of ineffective treatment are performed, the total effective rate reaches 87.5%, and no difference exists between the two groups (P is more than 0.05). (3) The scoring comparison of the number of times of stool, the stool characters, the abdominal distention and pain, the eructation, the vomiting and the dehydration symptoms and the like after the treatment course 1 has no statistical significance (P is more than 0.05), but the appetite is poor, the food intake scoring comparison has obvious difference between the two groups and has the statistical significance (P is less than 0.05), and the curative effect of the observation group is better than that of the control group. The scoring comparison of the stool frequency, stool characters, abdominal distension, eructation, vomiting, food intake and the like after 2 treatment courses has no statistical significance (P is more than 0.05), but the improvement of inappetence and dehydration has obvious difference (P is less than 0.05), and the curative effect of the observed group is better than that of the control group. Compared with abdominal pain scores, the abdominal pain scores have obvious difference (P < 0.05), and the curative effect of the control group is slightly better than that of the treatment group.
Conclusion: the Mongolian medicine navel patch of Enketype jin has better clinical curative effect on treating cold diarrhea of children, can obviously improve clinical symptoms and physical signs of children suffering from cold diarrhea, has no difference with the navel patch of Dinggui, but has better curative effect on improving inappetence and food intake than a control group.
Observation of therapeutic effect
(1) The main symptoms are as follows: diarrhea frequency, stool shape, tongue fur, urine volume and pulse condition;
(2) Secondary symptoms: abdominal pain, abdominal distension, nausea and vomiting, dehydration, inappetence, meal size and the like;
(3) Physical and chemical inspection: stool convention, blood convention, CRP, liver and kidney function, stool culture, stool cue ratio;
(4) The clinical symptoms and the physical signs of the infantile cold diarrhea are respectively classified, scored and integrated before treatment, after the first treatment course and after the second treatment course are finished.
Therapeutic effect criterion
Efficacy standard (efficacy assessment standard according to the guidelines of clinical research on new drugs of 2002-5 traditional Chinese medicine)
(1) Clinical recovery: the clinical symptoms and signs are all improved, and the integral of the symptoms is reduced by more than 95 percent;
(2) The effect is shown: the clinical symptoms and signs are all improved, and the integral of the symptoms is reduced by more than 70 percent;
(3) The method is effective: the clinical symptoms and signs are all improved, and the integral of the symptoms is reduced by more than 30 percent;
(4) Invalidation: the clinical symptoms and signs are all improved, and the integral reduction of the symptoms is less than 30 percent
Note that: the calculation formula is as follows: (nimodipine method) is [ (pre-treatment integral-post-treatment integral)/pre-treatment integral ] x100%;
clinical symptom efficacy index scoring criteria
Main symptoms are as follows: (1) number of faeces: 0 point: normally, 2 points: the number of times of defecation is less than 4 times/day, 4 parts: the number of times of defecation is 5-9 times/day, 6 minutes: the number of times of defecation is more than 10 times/day; (2) stool shape: 0 point: normally, 2 points: diarrhea indigestible food, 4 minutes: stool with mucus, 6 minutes: the stool is water-like;
secondary symptoms: (3) abdominal distension: 0 point: normal; 1, the method comprises the following steps: the symptoms are light, the abdominal distention is relieved or eliminated within half an hour, and the diet and the movement are not affected; 2, the method comprises the following steps: the duration of abdominal distention is 30 minutes < t < 1 hour, sometimes affecting diet and exercise; 3, the method comprises the following steps: the duration of abdominal distention is less than 2 hours, which affects diet and exercise; (4) abdominal pain: 0 point: normal; 1, the method comprises the following steps: the symptoms of abdominal pain are light; 2, the method comprises the following steps: pain relief after bowel movement; 3, the method comprises the following steps: pain is not relieved after defecation; (5) nausea and vomiting, score 0: normal; 1, the method comprises the following steps: sometimes nausea and vomiting (without affecting play); 2, the method comprises the following steps: nausea and vomiting after eating (sometimes without affecting play); 3, the method comprises the following steps: repeated nausea and vomiting, (affecting play, poor medication); (6) dehydration: 0 point: normal; 1, the method comprises the following steps: light weight; 2, the method comprises the following steps: a medium degree; 3, the method comprises the following steps: a severe degree; (7) appetite: 0 point: normal; 1, the method comprises the following steps: inappetence; 2, the method comprises the following steps: poor appetite and less meal; 3, the method comprises the following steps: inappetence and no meal; (8) the meal size is 0:: normal; 1, the method comprises the following steps: the meal quantity is small; 2, the method comprises the following steps: the meal quantity is less, and the usual quantity is reduced by 1/2;3, the method comprises the following steps: the meal quantity is less, and the usual quantity is reduced by 2/3;
results: (1) The two groups of children have no statistical significance (P > 0.05) in terms of gender, age, disease course, illness, symptoms, signs and the like. (2) After 1 treatment course, observing 2 cases of group cure, 8 cases of effective cases, 9 cases of effective cases, 13 cases of ineffective cases, and 59.38% of total effective rate; the control group heals 3 cases, 10 cases with obvious effect, 7 cases with effective effect, 12 cases with ineffective effect, the total effective rate is 62.5%, and the two groups have no difference (P is more than 0.05); after 2 treatment courses, 4 cases of group recovery are observed, 17 cases of effective treatment are performed, 6 cases of effective treatment and 5 cases of ineffective treatment, the total effective rate reaches 84.37%, 5 cases of control group recovery are performed, 16 cases of effective treatment are performed, 7 cases of effective treatment and 4 cases of ineffective treatment are performed, the total effective rate reaches 87.5%, and no difference exists between the two groups (P is more than 0.05). (3) The scoring comparison of the number of times of stool, the stool characters, the abdominal distention and pain, the eructation, the vomiting and the dehydration symptoms and the like after the treatment course 1 has no statistical significance (P is more than 0.05), but the appetite is poor, the food intake scoring comparison has obvious difference between the two groups and has the statistical significance (P is less than 0.05), and the curative effect of the observation group is better than that of the control group. The scoring comparison of the stool frequency, stool characters, abdominal distension, eructation, vomiting, food intake and the like after 2 treatment courses has no statistical significance (P is more than 0.05), but the improvement of inappetence and dehydration has obvious difference (P is less than 0.05), and the curative effect of the observed group is better than that of the control group. Compared with abdominal pain scores, the abdominal pain scores have obvious difference (P < 0.05), and the curative effect of the control group is slightly better than that of the treatment group.
Conclusion: the Mongolian medicine navel patch of Enketype jin has better clinical curative effect on treating cold diarrhea of children, can obviously improve clinical symptoms and physical signs of children suffering from cold diarrhea, has no difference with the navel patch of Dinggui, but has better curative effect on improving inappetence and food intake than a control group.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.
Claims (3)
1. The Mongolian navel patch for treating digestive system diseases is characterized by comprising the following components in parts by weight:
main medicine: 50-100 parts of pomegranate, 20-50 parts of cinnamon, 20-50 parts of fructus alpiniae oxyphyllae and 20-50 parts of fructus tsaoko;
adjuvant drug: 15-30 parts of dried ginger, 10-30 parts of long pepper, 20-50 parts of costustoot and 5-10 parts of safflower;
adjuvant drug: 10-30 parts of black grass seeds, 10-20 parts of table salt, 1-2 parts of sal ammoniac, 10-30 parts of white pepper and 10-30 parts of white jusheng;
the preparation method comprises the following steps: 15-30 parts of coriander fruits, 20-50 parts of clove, 20-30 parts of liquorice, and 10-20 parts of camphor.
2. A method for preparing a Mongolian navel patch for treating digestive system diseases according to claim 1, comprising the steps of:
s1, preparing raw materials: pomegranate, cinnamon, sharpleaf galangal fruit, long pepper, white pepper, table salt, sal ammoniac, tsaoko cardamon, safflower, black seed grass seed, bai Ju peptide, myrobalan, dried ginger, coriander fruit, clove, costustoot and liquorice, cleaning, airing, powdering and deslagging by a 100-mesh screen; grinding Borneolum Syntheticum and Camphora at low speed to obtain powder, and filtering with 100 mesh sieve to obtain residue;
s2, preparing an umbilical paste: placing all the powder medicines into a stirrer to be uniformly stirred, and preparing into cakes with the diameter of 1.5-3cm and the thickness of 0.3-1cm by using butter every 1.5-3.0 g; obtaining the navel patch.
3. The method for preparing a Mongolian navel patch for treating digestive system diseases according to claim 2, wherein the diameter of the medicinal cake is 2cm and the thickness is 0.5cm.
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