CN107583029A

CN107583029A - Chinese medicine composition for treating chronic enteritis and preparation method thereof

Info

Publication number: CN107583029A
Application number: CN201711077696.8A
Authority: CN
Inventors: 魏增强; 董文学
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-11-06
Filing date: 2017-11-06
Publication date: 2018-01-16

Abstract

The present invention provides a kind of Chinese medicine composition and preparation method for being used to treat chronic enteritis, and the Chinese medicine composition is composed of the following components by mass percentage：Nutmeg 7%~9%, Chinese anise 7%~9%, black pepper 1%~3%, the root of kudzu vine 5%~7%, lily 5%~7%, Poria cocos 7%~9%, purslane 7%~9%, Semen Lablab Album 7%~9%, wrinkled giant hyssop 4%~6%, fructus amomi 4%~6%, coix seed 7%~9%, lotus seeds 8%~10%, rhizoma zingiberis 4%~6%, honeysuckle 7%~9%, dark plum 5%~7%.Will above-mentioned component mix after plus water be boiled into after paste with maltodextrin and potassium sorbate mixing granulation, dry, sterilizing,.Chinese medicine of the present invention has the effect of tonifying spleen and kidney, stopping diarrhea with astringents, invigorating spleen to remove dampness, clearing heat and detoxicating, anti-inflammation；Whole prescription scientific compatibility, the property of medicine is gentle, integration of drinking and medicinal herbs, and to human body stomach fanout free region, human body is had no toxic side effect, can be long-term use of.

Description

Chinese medicine composition for treating chronic enteritis and preparation method thereof

Technical field

The invention belongs to the Chinese medicine composition of integration of drinking and medicinal herbs category, and in particular to a kind of Chinese medicine for being used to treat chronic enteritis Composition and preparation method thereof.

Background technology

Chronic enteritis is common clinical, frequently-occurring disease, and protracted inflammation is with the passing of time, touching refractory.More by bacterial infection, bacterial poison Element, or by eating and drinking without temperance, eating cold and uncooked food excessively, greasy food, cause gastrointestinal damage.It is clinical to show as interruption, irregular stomachache, abdomen more Rush down, atherosclerotic loose stools, or mucus watery stool, or mucopurulent bloody stool, defecation frequency increase, daily 2~3 times or more, the general course of disease It is longer, more than 3 months.The normal recurrent exerbation of chronic enteritis, weight when light during the state of an illness, because the course of disease is longer, nutrition lose it is more, it is right Patient body consumption is larger, due to dehydration, mistake salt when serious, can cause collapse.Do not controlled Ru prolonged, malnutrition can be caused, Even causing malnutrition property anaemia is very big to health effect.

This disease is treated, doctor trained in Western medicine is clinical to apply antibiotic more, but using with the passing of time, is also easy to produce resistance, unsatisfactory curative effect, while have again Cause the disadvantage of intestinal bacilli illness, cause symptom mitigation after the clinical patient medication having, recurred again after drug withdrawal, or often because suffering from cold Or diet does not break out in good time.This disease of Chinese traditional treatment then has obvious advantage, chronic enteritis category traditional Chinese medicine " diarrhea " category, and card type has Due to weakness of spleen and stomach, yang deficiency of spleen and stomache, irritable bowel syndrome type, silt resistance intestine collateral type several types, below to the chronic intestines of this several types Inflammation does following introduction：1. due to weakness of spleen and stomach symptom:Rush down, delay repeatedly, diarrhea with undigested food, indigestion and loss of appetite deficiency of food during half congealed during stool, after food not Relax, slightly enter greasy food, then times of defecation showed increased, sallow complexion is tired, and pale tongue is pale, and arteries and veins is thin and delicate；Analysis:Spleen Stomach it is weak and under lead to diarrhea, main by deficiency-weakness of spleen-QI, lucid yang failing to raise caused by transformation failure of spleen, therefore is shown in diarrhea, diarrhea with undigested food；It is insufficiency of the spleen Do not transport, then the vexed discomfort of gastral cavity after food of receiving is reduced or eaten, endless diarrhea；Deficiency of spleen-QI and stomach-QI, change source deficiency, cause sallow complexion, tired burnout； Pale tongue with white fur, arteries and veins is thin and delicate, belong to taste Virtual it is weak as.2. yang deficiency of spleen and stomache symptom:Navel week has a pain, and borborygmus is rushed down, and is then pacified after rushing down, The cold limb of shape is cold, soreness and weakness of waist and knees, pale tongue with white fur, deep thready pulse；Analysis：Decline of kidney-YANG, can not warm spleen sun；Shape is trembled with fear, and limb is cold, and waist and knee is sour It is soft, pale tongue with white fur, the sign of deep thready pulse, category insufficiency of both the spleen and the kindey deficiency.3. irritable bowel syndrome type symptom:It is known as Breast bilges frowsty, belch Deficiency of food, often because it is depressed it is angry or nervous when, that is, suffer from abdominal pain, suffer from diarrhoea, pink tongue, veins string；Analysis:Damaged by excess of seven emotions, mood is not Surely, when enraging, disorder of qi, liver loses bar and reached, and perverse and unreasonable manner multiplies spleen, loses its strong fortune, therefore stomachache is then rushed down；Liver-qi depression, catharsis is not normal, Therefore Breast bilges frowsty, eructation and poor appetite；Pale tongue, veins string, be liver-yang hyperactivity it is insufficiency of the spleen as.4. stagnation of blood stasis in the intestinal collateral type symptom:Diarrhea with the passing of time, after rushing down It is not well, belly shouting pain, fixed pain, by pain very, dark complexion, dry is not intended to drink, and there are ecchymosis or dimly red tongue, veins string in tongue side It is and puckery；Analysis:With the passing of time, disease and evil enters network to diarrhea, blood stasis intestines network, not general rule pain, therefore has belly shouting pain, fixed pain, by pain very； The stasis blocking stagnation of the circulation of vital energy, thus have rush down after sense not to the utmost；Dry is not intended to drink, dark complexion, and there is an ecchymosis on tongue side, dimly red tongue, veins string and it is puckery, For the sign of blood-stasis internal-depression.

The Chinese medicine that chronic enteritis is treated on existing market is largely to be directed to due to weakness of spleen and stomach, is all from invigorating the spleen benefit Start with what is treated in terms of gas clearing damp, for yang deficiency of spleen and stomache, this has resulted in this kind of patient and taken few medicines General treatment chronic enteritis medicine can not fundamentally treat chronic enteritis, cause therapeutic effect bad, delay the consequence of the state of an illness. Though chronic enteritis belongs to chronic refractory disease, as long as according to differentiation of tcm general principle, the position of serious analysis lesion, original Cause, property, and evil positive relationship, the essence and feature of the pathological change in a certain stage in disease progression are understood and grasped, Comprehensive overall condition, classification therapy is carried out to chronic enteritis, the effect of being satisfied with can be received surely.

The content of the invention

It is an object of the invention to provide a kind of Chinese medicine composition for treating chronic enteritis, using the treatment hand of solid decoction of medicinal ingredients Section, for the treatment of yang deficiency of spleen and stomache chronic enteritis, therapeutic effect is good, uneasy to recur.

The technical solution adopted in the present invention is,

It is raw materials used composed of the following components by mass percentage for treating the Chinese medicine composition of chronic enteritis：

Nutmeg 7%~9%, Chinese anise 7%~9%, black pepper 1%~3%, the root of kudzu vine 5%~7%, lily 5%~ 7%th, Poria cocos 7%~9%, purslane 7%~9%, Semen Lablab Album 7%~9%, wrinkled giant hyssop 4%~6%, fructus amomi 4%~6%, Job's tears Benevolence 7%~9%, lotus seeds 8%~10%, rhizoma zingiberis 4%~6%, honeysuckle 7%~9%, dark plum 5%~7%, above each component Mass percent summation be 100%.

The above-mentioned preparation method for being used to treat chronic enteritis Chinese medicine composition, including following operating procedure：

Step 1,

By mass percentage, nutmeg 7%~9%, Chinese anise 7%~9%, black pepper 1%~3%, the root of kudzu vine are weighed 5%~7%, lily 5%~7%, Poria cocos 7%~9%, purslane 7%~9%, Semen Lablab Album 7%~9%, wrinkled giant hyssop 4%~ 6%th, fructus amomi 4%~6%, coix seed 7%~9%, lotus seeds 8%~10%, rhizoma zingiberis 4%~6%, honeysuckle 7%~9%, crow Plum 5%~7%, the mass percent summation of above each component is 100%；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts, decocted 2 hours, are added for the second time The water of 6 times of amounts, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into relative density as 1.20~1.40 (60 DEG C) Thick paste；

Step 3,

Maltodextrin and potassium sorbate separately are taken, and maltodextrin and potassium sorbate be crushed into 80 mesh, it is standby；

Step 4,

By mass percentage, thick paste 24%~26.97%, the and of maltodextrin 73%~75.97% that step 2 obtains are weighed Potassium sorbate 0.01%~0.03%, the mass percent summation of above each component is 100%；Thick paste and water are stirred To whitewashing, the weight ratio of thick paste and water is 1:2；

Step 5,

In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating premix, obtain mixed material, so Pelletized afterwards toward whitewashing on mixed material, finally dry, cool, discharging, shutdown；

Step 6,

Last whole grain and filling, is produced.

In above-mentioned steps 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 15m³/ h~ 25m³/ h, EAT are arranged to 80 DEG C~100 DEG C, heating premix are carried out to material 7~15 minutes, obtain mixed material；In advance After mixed, by adjusting air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, then multi-functional fluidisation Bed starts to whitewash, and spouting velocity is arranged to 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, due to thing after whitewashing Material aggravates, and temperature reduces, and adjusts air quantity at any time and keeps material fully to jump, and regulation EAT keeps temperature of charge at any time At 35 DEG C~40 DEG C, whitewashing is closed after the 15min~30min that whitewashes, completes granulation；Multifunctional fluidized bed EAT is set again It is set to 100 DEG C material is dried, regulation air quantity keeps material fully to jump, when the moisture≤2.0% of material, by air intake Temperature is down to 25 DEG C~45 DEG C, the temperature of material is reduced to 25 DEG C~45 DEG C, finally discharging shutdown.

In above-mentioned steps 6, the particle that dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 is completed Whole grain, then the dry particl of selection is fitted into bag complete it is filling.

The beneficial effects of the invention are as follows：There are tonifying spleen and kidney, stopping diarrhea with astringents, invigorating spleen to remove dampness, clearing heat and detoxicating, anti-inflammation work( Effect；Whole prescription scientific compatibility, the property of medicine is gentle, integration of drinking and medicinal herbs, and to human body stomach fanout free region, human body is had no toxic side effect, can be grown Phase takes.

Embodiment

The present invention provides a kind of Chinese medicine composition for being used to treat chronic enteritis, raw materials used by mass percentage by following Component forms：

The pharmacological action of Chinese medicine of the present invention is as follows：

Nutmeg：It is pungent, temperature, returns spleen stomach large intestine channel middle benefit gas promoting the circulation of qi, relieving diarrhea with astringents, for deficiency-cold in spleen and stomach, endless diarrhea, gastral cavity abdomen Distending pain, deficiency of food vomiting.

Chinese anise：It is pungent, temperature, returns spleen stomach and liver kidney channel warming yang for dispelling cold, regulating qi-flowing for relieving pain；For cold hernia stomachache, lumbago due to the kidney deficiency, stomach Cold vomiting, coldness and pain in the epigastrium.

Black pepper：Warming spleen and stomach for dispelling cold, lower gas, dissolving phlegm, for gastrofrigid vomiting, diarrhea of suffering from abdominal pain, poor appetite, epilepsy abundant expectoration.

The root of kudzu vine：Expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid to quench thirst, promoting eruption, and Shengyang Zhixie is clearing and activating the channels and collaterals, relieving alcoholism, for fever caused by exogenous pathogens head Bitterly, stiff nape and back, it is thirsty, quench one's thirst, measles without adequate eruption, hot dysentery, diarrhea, dizziness and headache, hemiplegia, chest impediment and cardialgia, during wine poison is hindered.

Lily：It is sweet, to tremble with fear, thoughts of returning home lung channel Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, for deficiency of Yin cough caused by dryness, consumptive disease is coughed hemoptysis, dysphoria palpitates with fear, Insomnia and dreamful sleep, it is absent-minded.

Poria cocos：Clearing damp and promoting diuresis, invigorating the spleen, calming heart, for oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind Uneasiness, insomnia of palpitating with fear.

Purslane：Acid, tremble with fear, Return liver, large intestine channel is clearing heat and detoxicating, cooling blood and hemostasis, stop dysentery；For toxic-heat and blood stasis, carbuncle swells furunculosis, Eczema, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoid blood, metrostaxis；Purslane has good antibacterial and anti-inflammation functions, to Escherichia coli, Shigella, salmonella, proteus, bacillus subtilis, staphylococcus aureus have stronger inhibitory action, to total The red mould, aspergillus flavus of shape, Mucor equally have inhibitory action.

Semen Lablab Album：It is sweet, tepor, returns spleen stomach invigorating the spleen for eliminating dampness, and in relieve summer heat；For weakness of the spleen and the stomach, poor appetite, big loose stool Write, leukorrhea, summer-heat and damp is vomited and diarrhoea, abdominal distension uncomfortable in chest；Semen Lablab Album invigorating the spleen for eliminating dampness is fried, for splenasthenic diarrhea, leukorrhea.

Wrinkled giant hyssop：Eliminate dampness with aromatics, and middle preventing or arresting vomiting, relieving summer-heat is delivered, for turbi damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted, summer-heat and damp table disease, at the beginning of damp-warm syndrome Rise, burnout of generating heat is uncomfortable in chest not relax, and cold-dampness closes heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.

Fructus amomi：Dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive；Let out for turbi damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting Rush down, pernicious vomiting, fetal irritability.

Coix seed：Clearing damp and promoting diuresis, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, detoxicating and resolving a mass, for oedema, tinea pedis, difficult urination, it is good for It is the splenic diarrhea to rush down, arthritis with fixed pain caused by dampness contraction, lung carbuncle, acute appendicitis, cancerous swelling.

Lotus seeds：Tonifying spleen and stopping diarrhea, stop-band, the puckery essence of kidney-nourishing, mental-tranquilization, for splenasthenic diarrhea, with, pass out semen, palpitation and insomnia.

Rhizoma zingiberis：Nature and flavor acrid, bitter, warm, enter spleen, Liver Channel, promoting the circulation of qi, stimulate the menstrual flow, relieve pain；For warming up spleen sun, malaria stomachache is controlled partially and is let out Rush down, and can Back to Yang Tongmai is warming lung and reducing phlegm, is fainted with four limbs inverse, feeble and impalpable pulse, and cold drink cough and asthma, and the cold back of the body of shape is cold, and abundant expectoration is thin etc. Disease.Rhizoma zingiberis has back the effect of positive：For diarrhea with undigested food in the stool, cold in the interior and heat in the exterior, deadly cold hand and foot, weak pulse deficiency of yang disease to be taken off；Rhizoma zingiberis has temperature The effect of middle：For deficiency-cold in spleen and stomach, the thin odorless of diarrhea, borborygmus stomachache person；Rhizoma zingiberis has the effect of warming lung and reducing phlegm：For lung cold Cough；Rhizoma zingiberis has the effect of warming channel for arresting bleeding：Haematemesis for deficient cold type, have blood in stool, the card such as metrorrhagia.

Honeysuckle：It is sweet, tremble with fear, return lung heart stomach is clearing heat and detoxicating, dispelling wind and heat from the body, for carbuncle swells furunculosis, larynx numbness, erysipelas, heat toxin Bloody flux, anemopyretic cold, warm disease heating；Honeysuckle is double to staphylococcus aureus, hemolytic streptococcus, pneumobacillus, meningitis Coccus, typhoid bacillus, paratyphosum Bacterium, Escherichia coli, shigella dysenteriae, proteus, Bordetella pertussis, pseudomonas aeruginosa, A variety of Gram-positives such as tubercle bacillus, comma bacillus and negative bacterium are respectively provided with certain inhibitory action, and fungistatic effect is with concentration Increase and be remarkably reinforced.

Dark plum：Sour and astringent flat, Return liver spleen and lung large intestine channel is astringed the lung, and puckery intestines, is promoted the production of body fluid, claming ascaris；For chronic cough of deficiency lung, protracted dysentery and diarrhea, Abnormal heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache.

Let out when half congealed during chronic enteritis, recurrent exerbation, the person of not recovering for a long time, diarrhoea, mucus purulence are had blood in stool, suffered from abdominal pain and tenesmus； For the chronic enteritis of yang deficiency of spleen and stomache, suitable invigorating spleen to remove dampness is controlled, it is tonifying spleen and kidney.According to《Chinese Pharmacopoeia》, it is nutmeg in side, white flat Beans, wrinkled giant hyssop, fructus amomi, coix seed, invigorating the spleen for eliminating dampness, stopping diarrhea with astringents；Chinese anise, black pepper, rhizoma zingiberis, the sun of warm spleen kidney；Dark plum, Fu Siberian cocklebur, lotus seeds, rhizoma zingiberis, it is sour and astringent and warm, astringing to arrest bleeding mucus, only suffer from abdominal pain；Honeysuckle, purslane, clearing heat and detoxicating, anti-inflammation； The root of kudzu vine, lily, care for shield QI of the spleen and stomach.In view of weakness due to chronic disease, in order to which impairing the spleen and stomach, full side do not send survival dose, heat is cold without dry Without hardship, attack but, mend and oiliness, play invigorating spleen to remove dampness, tonifying spleen and kidney work(, to reach the purpose of rehabilitation chronic enteritis altogether.

Chinese medicine composition of the present invention is by the way of oral, and oral 10 grams every time, 2 times a day, one month is a course for the treatment of.

With reference to specific embodiment, the present invention is described in detail.

Embodiment 1

For treating the preparation method of chronic enteritis Chinese medicine composition, including following operating procedure：

Step 1,

Weigh nutmeg 7kg, Chinese anise 9kg, black pepper 3kg, root of kudzu vine 7kg, lily 5kg, Poria cocos 7kg, purslane 9kg, Semen Lablab Album 7kg, wrinkled giant hyssop 4kg, fructus amomi 5kg, coix seed 9kg, lotus seeds 10kg, rhizoma zingiberis 4kg, honeysuckle 7kg, dark plum 7kg；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts, decocted 2 hours, are added for the second time The water of 6 times of amounts, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into the thick paste that relative density is 1.35 (60 DEG C)；

Step 3,

Step 4,

Weigh thick paste 20.5kg, maltodextrin 61.5kg and potassium sorbate 20g；Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2；

Step 5,

By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 20m³/ h, EAT are set For 90 DEG C, heating premix is carried out to material 10 minutes, obtain mixed material；After premix, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 36 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is arranged to 17rpm, atomization Pressure is 1.70bar, and because material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge be maintained at 36 DEG C, closes whitewashing after the 20min that whitewashes, completes granulation；Again by multi-functional fluidisation The EAT of bed is arranged to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 25 DEG C, the temperature of material is reduced to 25 DEG C, finally discharging shutdown；

Step 6,

The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will The dry particl of selection be fitted into bag complete it is filling.

Embodiment 2

Step 1,

Weigh nutmeg 9kg, Chinese anise 9kg, black pepper 2kg, root of kudzu vine 5kg, lily 6kg, Poria cocos 7kg, purslane 8kg, Semen Lablab Album 8kg, wrinkled giant hyssop 5kg, fructus amomi 5kg, coix seed 8kg, lotus seeds 8kg, rhizoma zingiberis 6kg, honeysuckle 8kg, dark plum 6kg；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts, decocted 2 hours, are added for the second time The water of 6 times of amounts, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into the thick paste that relative density is 1.20 (60 DEG C)；

Step 3,

Step 4,

Weigh thick paste 24kg, maltodextrin 75.97kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing, The weight of thick paste and water ratio is 1:2；

Step 5,

By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 25m³/ h, EAT are set For 80 DEG C, heating premix is carried out to material 7 minutes, obtain mixed material；After premix, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 40 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is arranged to 15rpm, atomization Pressure is 1.50bar, and because material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge be maintained at 40 DEG C, closes whitewashing after the 15min that whitewashes, completes granulation；Again by multi-functional fluidisation The EAT of bed is arranged to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 35 DEG C, the temperature of material is reduced to 35 DEG C, finally discharging shutdown；

Step 6,

Embodiment 3

Step 1,

Weigh nutmeg 9kg, Chinese anise 7kg, black pepper 1kg, root of kudzu vine 6kg, lily 7kg, Poria cocos 8kg, purslane 7kg, Semen Lablab Album 9kg, wrinkled giant hyssop 5kg, fructus amomi 4kg, coix seed 9kg, lotus seeds 9kg, rhizoma zingiberis 5kg, honeysuckle 9kg, dark plum 5kg；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts, decocted 2 hours, are added for the second time The water of 6 times of amounts, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into the thick paste that relative density is 1.30 (60 DEG C)；

Step 3,

Step 4,

Weigh thick paste 26.97kg, maltodextrin 73kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing, The weight of thick paste and water ratio is 1:2；

Step 5,

By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 15m³/ h, EAT are set For 100 DEG C, heating premix is carried out to material 12 minutes, obtain mixed material；After premix, by adjusting air quantity and entering wind-warm syndrome Degree so that when mixed material temperature reaches 38 DEG C, then multifunctional fluidized bed to start to whitewash, spouting velocity is arranged to 18rpm, mist Change pressure is 2.0bar, and because material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and keeps material fully to jump, and with When regulation EAT temperature of charge is maintained at 38 DEG C, close whitewashing after the 30min that whitewashes, complete granulation；Again by multi-functional stream The EAT of change bed is arranged to 100 DEG C and material is dried, and regulation air quantity keeps material fully to jump, when the moisture of material When≤2.0%, EAT is down to 30 DEG C, the temperature of material is reduced to 30 DEG C, finally discharging shutdown；

Step 6,

Embodiment 4

Step 1,

Weigh nutmeg 8kg, Chinese anise 8kg, black pepper 2kg, root of kudzu vine 7kg, lily 6kg, Poria cocos 9kg, purslane 7kg, Semen Lablab Album 7kg, wrinkled giant hyssop 6kg, fructus amomi 6kg, coix seed 7kg, lotus seeds 10kg, rhizoma zingiberis 5kg, honeysuckle 7kg, dark plum 5kg；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts, decocted 2 hours, are added for the second time The water of 6 times of amounts, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into the thick paste that relative density is 1.40 (60 DEG C)；

Step 3,

Step 4,

Weigh thick paste 24.02kg, maltodextrin 75.97kg and potassium sorbate 10g；Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2；

Step 5,

By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 20m³/ h, EAT are set For 95 DEG C, heating premix is carried out to material 15 minutes, obtain mixed material；After premix, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 35 DEG C, and then multifunctional fluidized bed to start to whitewash, spouting velocity is arranged to 20rpm, atomization Pressure is 1.70bar, and because material aggravates after whitewashing, temperature reduces, and adjusts air quantity at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge be maintained at 35 DEG C, closes whitewashing after the 25min that whitewashes, completes granulation；Again by multi-functional fluidisation The EAT of bed is arranged to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 45 DEG C, the temperature of material is reduced to 45 DEG C, finally discharging shutdown；

Step 6,

Clinical data：

1st, case selection：

In order to verify the therapeutic effect of Chinese medicine composition of the present invention, 2 months in October, 2015-2017 year, the spleen made a definite diagnosis is selected 120 clinical observations of kidney yang deficiency syndrome patients having chronic intestinal inflammation, wherein male 58, women 62, age 15-62 year, average age 37.8 years old, the course of disease 3 months~4 years.

Make a definite diagnosis standard：

(1) recurrent exerbation stomachache, diarrhoea, to the cold or eat greasy food and then aggravate, after anxious state of mind or fatigue more very；Abdomen Have a pain in navel week before rushing down, borborygmus is rushed down, and is then pacified after rushing down；For daily defecation more than 3 times, excrement matter is thin, or such as water sample；

(2) adjoint spiritlessness and weakness, deficiency of QI with disinclination to talk, happiness temperature are cold, the cold limb of shape is cold, soreness and weakness of waist and knees symptom；

(3) more than 3 months persons of abdominal pain diarrhea recurrent exerbation.

2nd, medicament selection：

120 patients take medicine of the present invention, 2 times a day, each 10g, warm water delivery service in half an hour after meal, are within 30 days One course for the treatment of, continuously takes 2 to 3 courses for the treatment of, and serious patient increases the amount of discretion.

3rd, efficacy determination：

(1) cure：Subjective symptoms disappears, and diet, stool are normal, and enteroscopy is without obvious enteritis pathological phenomenon；

(2) it is effective：Subjective symptoms disappears, but coherence check is still with the presence of enteritis pathology；

(3) effectively：Subjective symptoms substantially mitigates, but has repeatedly, and checks that enteritis pathology is not improved；

(4) it is invalid：Symptom is without improving or having improvement but unobvious, and repeatability is larger.

4th, result：

Take in 120 patients of medicine of the present invention, healing 84, effective 20, effective 10, invalid 6, cure rate For 70%, total effective rate 95%.

Case 1

The Mr. Wang, male of Xi'an City, Shanxi Province, 48 years old；Patient suffered from diarrhoea as long as half a year, daily stool 5-6 times, when good during the state of an illness It is bad, no purulence blood of defecating, there are mucus or blister, suffer from abdominal pain；With pale complexion, clear abundant urine, lassitude, weakness of limbs, appetite Bad, happiness temperature is cold, and the cold limb of shape is cold, the symptom of soreness and weakness of waist and knees；In outpatient service internal medicine inspection, cardiopulmonary are normal, and abdomen is soft, and lower abdomen has pressure Bitterly, there is tympanitic note during lower abdomen percussion；Come here to go to a doctor, the thin string of patient's arteries and veins, pale tongue with thin fur is white；Through dialectical：Belong to the diarrhea of the insufficiency of both the spleen and the kindey, Control suitable tonifying spleen warm kidney, stopping diarrhea with astringents；Take Chinese medicine of the present invention, daily two doses (one 10g), after 2 courses for the treatment of, symptom is substantially good Turn, defecate daily 2-3 times, shape, no mucus and blister, and appetite is promoted, spiritual increasingly amelioration；Continue to take 2 courses for the treatment of, then Further consultation, stool are 1 time a day, now interior without recurrence without any symptom, recovery from illness, half a year.

Case 2

Lee of Xianyang, Shanxi province city Qian County, 34 years old, female；Suffer from diarrhoea for many years, big loose stool, four times a day or so, diarrhea with undigested food, Especially at day getting up early is had loose bowels just, there is a small amount of mucus, just when abdominal pain pain, then pacify after rushing down, tastelessness and no thirst, hot drink preference food, drink To eat raw and cold and greasy then diarrhoea to aggravate, make usually in abdomen during borborygmus, indigestion and loss of appetite gastral cavity is vexed, neurolysis, deficiency of QI with disinclination to talk, hands and feet being not warm, It is often dizzy.The disease for yang-deficiency chronic diarrhea is examined, after taking three courses for the treatment of of Chinese medicine of the present invention, patient's symptom of diarrhea disappears, stool shaping, Stool is once a day；Continue after taking a course for the treatment of, patient mental is abundant, and sleep quality is high, no longer suffers from diarrhoea, brothers are warm, body Body rehabilitation, recovery from illness, without recurrence in half a year.

Case 3

The Zhang of Shaanxi Province Weinan city Linwei district, 54 years old, man；Daily morning wakes up, and feels to suffer from abdominal pain, borborygmus, anxious stool, Then disease disappears after an action of the bowels, daily to defecate 2-3 times, for 1 year；Lean body mass, complexion are without damp, weak burnout, to snuggle up to cold limb cold；Clothes With then symptom of diarrhea mitigates or disappeared after antidiarrheal agent, diarrhoea recurrence is as before after drug withdrawal；Come here to go to a doctor, through dialectical：Belong to spleen kidney yang The diarrhea of void, control astringent or styptic treatment for spontaneous sweating, the strong kidney of suitable warm spleen and warm up limb；Take daily two doses (one 10g) after this formula, after 3 courses for the treatment of, symptom is bright Aobvious to take a turn for the better, belly is comfortable, and once a day, stool shapes stool, no morning diarrhea phenomenon, recovery from illness, without recurrence in half a year.

Claims

1. the Chinese medicine composition for treating chronic enteritis, it is characterised in that raw materials used by mass percentage by following components Composition：

Nutmeg 7%~9%, Chinese anise 7%~9%, black pepper 1%~3%, the root of kudzu vine 5%~7%, lily 5%~7%, Poria cocos 7%~9%, purslane 7%~9%, Semen Lablab Album 7%~9%, wrinkled giant hyssop 4%~6%, fructus amomi 4%~6%, coix seed 7%~9%, lotus seeds 8%~10%, rhizoma zingiberis 4%~6%, honeysuckle 7%~9%, dark plum 5%~7%, above each component Mass percent summation is 100%.

2. be used to treat the preparation method of chronic enteritis Chinese medicine composition described in a kind of claim 1, it is characterised in that including with Lower operating procedure：

Step 1,

By mass percentage, weigh nutmeg 7%~9%, Chinese anise 7%~9%, black pepper 1%~3%, the root of kudzu vine 5%~ 7%th, lily 5%~7%, Poria cocos 7%~9%, purslane 7%~9%, Semen Lablab Album 7%~9%, wrinkled giant hyssop 4%~6%, fructus amomi 4%~6%, coix seed 7%~9%, lotus seeds 8%~10%, rhizoma zingiberis 4%~6%, honeysuckle 7%~9%, dark plum 5%~ 7%, the mass percent summation of above each component is 100%；

Step 2,

15 taste raw materials in step 1 are added water to cook twice, add the water of 10 times of amounts for the first time, are decocted 2 hours, second plus 6 times The water of amount, decoct 2 hours, merge decocting liquid twice, filtering, filtrate is concentrated into relative density as the thick of 1.20~1.40 (60 DEG C) Cream；

Step 3,

Step 4,

By mass percentage, thick paste 24%~26.97%, maltodextrin 73%~75.97% and sorb that step 2 obtains are weighed Sour potassium 0.01%~0.03%, the mass percent summation of above each component is 100%；Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2；

Step 5,

In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating premix, obtain mixed material, it is then past Whitewashing is pelletized on mixed material, is finally dried, is cooled, discharging, shutdown；

Step 6,

Last whole grain and filling, is produced.

3. it is used for the preparation method for treating chronic enteritis Chinese medicine composition according to claim 2, it is characterised in that：The step In rapid 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is arranged to 15m³/ h~25m³/ h, EAT 80 DEG C~100 DEG C are arranged to, heating premix is carried out to material 7~15 minutes, obtains mixed material；After premix, pass through tune Save air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, then multifunctional fluidized bed to start to whitewash, whitewashing Speed is arranged to 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, and because material aggravates after whitewashing, temperature reduces, Adjusting air quantity at any time keeps material fully to jump, and regulation EAT makes temperature of charge be maintained at 35 DEG C~40 DEG C at any time, spray Whitewashing is closed after starching 15min~30min, completes granulation；Multifunctional fluidized bed EAT is arranged to 100 DEG C to material again Be dried, regulation air quantity keeps material fully to jump, when the moisture≤2.0% of material, by EAT be down to 25 DEG C~ 45 DEG C, the temperature of material is set to be reduced to 25 DEG C~45 DEG C, finally discharging shutdown.

4. it is used for the preparation method for treating chronic enteritis Chinese medicine composition according to claim 2, it is characterised in that：The step In rapid 6, the particle that dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will choosing The dry particl taken be fitted into bag complete it is filling.