CN106728820A - A kind of disinfectant antipruritic ointment and preparation method thereof - Google Patents

A kind of disinfectant antipruritic ointment and preparation method thereof Download PDF

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CN106728820A
CN106728820A CN201611077705.9A CN201611077705A CN106728820A CN 106728820 A CN106728820 A CN 106728820A CN 201611077705 A CN201611077705 A CN 201611077705A CN 106728820 A CN106728820 A CN 106728820A
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tuber
dwarf lilyturf
radix
aloe
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孔兰昕
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Guangxi University
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Guangxi University
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Abstract

The invention discloses a kind of disinfectant antipruritic ointment and preparation method thereof, belong to technical field of traditional Chinese medicines, the ointment is mainly obtained by following raw material:3 14 parts of 4 17 parts of aloe, 4 15 parts of Radix Cinnamomi Camphorae, 3 15 parts of radix bupleuri, 2 12 parts of peppermint, 3 10 parts of golden cypress, 29 parts of hypericum perforatum, 48 parts of betel nut, 1 10 parts of the tuber of dwarf lilyturf, 3 11 parts of the coptis, 4 11 parts of greater celandine, 5 10 parts of Radix Glycyrrhizae, 28 parts of the root of gansui, 39 parts of cortex albiziae, 26 parts of the tuber of dwarf lilyturf, 37 parts of frutus cnidii, 28 parts of Japanese Cayratia Herb, 58 parts of folium artemisiae argyi, 5 15 parts of deionized water and vaseline.Medicinal material compatibility selected by disinfectant antipruritic ointment of the invention is suitable, and with clearing heat and detoxicating, disinfectant antipruritic, bactericidal, without bad and toxic and side effect advantage, according to clinical verification, having to treatment pruitus preferably alleviate and therapeutic effect.

Description

A kind of disinfectant antipruritic ointment and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of disinfectant antipruritic ointment and preparation method thereof.
Background technology
Pruitus is a kind of conscious pruitus and the skin disease without primary lesion.General skin can be clinically divided into Skin itch and limitation pruitus, are confined to anus and external genital the latter more.General pruitus common cause divides in Imbalance and winter itch are secreted, liver and kidney disease, malignant tumour and spiritual sexual factor can also cause itch, and excessive cleaning skin is made The reason for producing itch pruitus into skin degreaser drying is complicated, it is demonstrated experimentally that there is the receptor of gargalesthesia in the skin of dog, And brain is transmitted to by nerve endings.The release of affected tissue amine can promote gargalesthesia.Scratch because tenderness has itching-relieving action, but promote Enter to discharge more histamines, aggravate gargalesthesia, the vicious circle that formation is itched-grabbed causes even more serious skin injury and inflammation.
For many application western medicines of pruitus on modern clinic, but have side effect greatly, apply long with the time, have mostly It is additive, high recurrence rate after drug withdrawal, it is impossible to effect a radical cure.The traditional Chinese medical science thinks, it is pruitus that ailment said due to cold or exposure, damp evil, heat evil, the deficiency of blood, worm are excessive etc. Pathogenic main cause, protects skin, treatment with dispelling wind clearing damp, clearing heat and detoxicating, enriching the blood to restore normal menstruation, promoting blood circulation and removing blood stasis as principle, to reach drive The effect of evil righting is antipruritic.
The content of the invention
Instant invention overcomes the shortcoming of above-mentioned technical problem, there is provided a kind of disinfectant antipruritic ointment and preparation method thereof, institute Select medicinal material compatibility suitable, with clearing heat and detoxicating, disinfectant antipruritic, bactericidal, without bad and toxic and side effect advantage, is tested through clinic Card, having to treatment pruitus preferably alleviate and therapeutic effect.
To realize above-mentioned technical purpose, technical scheme is as follows:
A kind of disinfectant antipruritic ointment, is mainly obtained by following raw material:Aloe 4-17 parts, Radix Cinnamomi Camphorae 4-15 parts, Radix bupleuri 3-15 parts, peppermint 2-12 parts, golden cypress 3-10 parts, hypericum perforatum 2-9 parts, betel nut 4-8 parts, tuber of dwarf lilyturf 1-10 parts, coptis 3-11 Part, greater celandine 4-11 parts, Radix Glycyrrhizae 5-10 parts, root of gansui 2-8 parts, cortex albiziae 3-9 parts, tuber of dwarf lilyturf 2-6 parts, frutus cnidii 3-7 parts, Japanese Cayratia Herb 2-8 parts, folium artemisiae argyi 5-8 parts, deionized water 5-15 parts and vaseline 3-14 parts.
Preferably, the disinfectant antipruritic ointment is mainly obtained by following raw material:Aloe 5-15 parts, Radix Cinnamomi Camphorae 5- 14 parts, radix bupleuri 4-13 parts, peppermint 4-10 parts, golden cypress 4-9 parts, hypericum perforatum 3-8 parts, betel nut 5-7 parts, tuber of dwarf lilyturf 2-8 parts, coptis 4- 10 parts, greater celandine 5-9 parts, Radix Glycyrrhizae 6-9 parts, root of gansui 3-7 parts, cortex albiziae 4-8 parts, tuber of dwarf lilyturf 3-5 parts, frutus cnidii 4-6 parts, Japanese Cayratia Herb 3-7 parts, folium artemisiae argyi 4-7 parts, deionized water 6-14 parts and vaseline 5-12 parts.
Preferably, the disinfectant antipruritic ointment is mainly obtained by following raw material:10 parts of aloe, Radix Cinnamomi Camphorae 12 It is part, 10 parts of radix bupleuri, 8 parts of peppermint, 7 parts of golden cypress, 6 parts of hypericum perforatum, 6 parts of betel nut, 5 parts of the tuber of dwarf lilyturf, 6 parts of the coptis, 7 parts of greater celandine, sweet 8 parts of grass, 5 parts of the root of gansui, 5 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 6 parts of Japanese Cayratia Herb, deionized water, 5 parts of folium artemisiae argyi, deionized water 8 parts and 10 parts of vaseline.
Preferably, the disinfectant antipruritic ointment is mainly obtained by following raw material:12 parts of aloe, Radix Cinnamomi Camphorae 13 It is part, 12 parts of radix bupleuri, 5 parts of peppermint, 5 parts of golden cypress, 5 parts of hypericum perforatum, 6 parts of betel nut, 4 parts of the tuber of dwarf lilyturf, 7 parts of the coptis, 8 parts of greater celandine, sweet 7 parts of grass, 4 parts of the root of gansui, 7 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 4 parts of Japanese Cayratia Herb, 5 parts of folium artemisiae argyi, 10 parts of deionized water and all 11 parts of intellectual circle.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into grinder grind into powder;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Preferably, in the step (3), the mesh number of the powder is 120-150 mesh.
Chinese medicine details in the present invention is as follows:
Aloe, bitter is trembled with fear, nontoxic;The germs such as fungi, mould, bacterium, virus can be killed, is suppressed and eliminating pathogen Development breeding, the bradykinin enzyme of aloe is combined with vasotonia can resist inflammation;The polysaccharide of aloe can strengthen human body to disease The resistance of disease, cures dermatitis, chronic nephritis, cystitis, bronchitis chronic diseases disease;Aloe polysaccharide and vitamin are to people The skin of body has good nutrition, moist, whitening effect.
Radix Cinnamomi Camphorae, taste is pungent is nontoxic, with vital energy regualting and blood circulation-promoting, except effect of rheumatism.Control and suffer from vomiting and diarrhoea, trusted subordinate's distending pain, rheumatism Numbness disease, traumatic injury, mange itch.
Radix bupleuri, gas micro-perfume, mildly bitter flavor, cold nature.Return liver, gallbladder channel.Can antipyretic, anti-inflammatory, it is past for cold, fever, fever and chills Next, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus come off, irregular menstruation.
Peppermint, taste is pungent is cool.Enter lung channel, Liver Channel, can dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi, for outer Sense wind-heat, headache, abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria, warm disease from the beginning of, rubella itch, stagnation of QI due to depression of the liver, Hypochondriac pain uncomfortable in chest.
Golden cypress, bitter is cold in nature, kidney channel, bladder, large intestine channel.Can be clearing heat and detoxicating, purging intense heat eliminating dampness cure mainly acute bacterial dysentery Burning hot wound, tympanitis, acute conjunctivitis are controlled in the inflammation such as disease, chordapsus, acute icteric hepatitis, urinary system infection contamination, external application Deng.
Hypericum perforatum, it is bitter, puckery, mild-natured.Return liver warp.Astringing to arrest bleeding, menstruation regulating lead to newborn, clearing heat and detoxicating, dampness removing, main spitting of blood, Haematemesis, discharging fresh blood stool, uterine bleeding, traumatism and bleeding, menstruation fry adjust, newborn woman's agalactia, jaundice, have sore throat, red eye, swell pain, urinary tract Infection, mouth and nose life sore, carbuncle furuncle poison, burn and scald.
Betel nut, it is bitter, pungent, warm in nature.Return stomach, large intestine channel, can expelling parasite, disperse accumulations, lower gas, water-filling, preventing malaria.To malnutrition due to parasitic infestation, food stagnation, Abdominal distention, weight after rush down dysentery, tinea pedis, oedema, malaria are effective.
The tuber of dwarf lilyturf, sweet, slight bitter is slightly cold.The thoughts of returning home, lung, stomach, can Yin-nourishing and body fluid promoting, moisten the lung and relieve the cough, relieving restlessness that clears away heart-fire.Cure mainly heat Disease hinders Tianjin, vexed, thirsty, dry throat lung heat, cough, pulmonary tuberculosis, and modern medicine study confirms that the tuber of dwarf lilyturf is to corynebacterium diphtheriae, hemolytic Streptococcus and staphylococcus aureus have inhibitory action.
The coptis, bitter is cold in nature, the thoughts of returning home, spleen, stomach, liver, courage, large intestine channel, and for retention of damp-heat in the interior, stomach is damp and hot, vomit, rush down Dysentery etc., modern medicine study confirms that the coptis is to staphylococcus aureus, hemolytic streptococcus, pneumococcus, the double balls of meningitis Bacterium, shigella dysenteriae and bacillus anthracis etc. are respectively provided with inhibitory action, are a kind of antibacterial materials of natural wide spectrum, can play sterilization, Effect of anti-inflammatory.
Greater celandine, cool in nature, bitter is slightly poisonous;Return lung, the heart, kidney channel;Lower internal heat, brings down a fever antipyretic, anti-inflammation and sterilization, town of easing pain It is quiet, control paddy-field dermatitis, insect-bite, mange.
Radix Glycyrrhizae, it is sweet, put down, it is nontoxic, enter spleen, stomach, lung channel.Invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, tune With all medicines.The thin face Huang of main burnout deficiency of food, flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Swell and ache;Ulcerative carbuncle swells and ache;Infant fetal toxin;And medicine, food poisoning, for weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, phlegm of coughing Many, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
The root of gansui, bitter is cold in nature;Returns spleen warp, lung channel, kidney channel, bladder warp, large intestine channel, small intestinl channel.Oedema is cured mainly, ascites is stayed Drink accumulation of pathogens in chest, epilepsy is breathed with cough, and sphincter disturbance, modern medicine study confirms that the root of gansui is to pneumococcus Escherichia coli, shigella dysenteriae And bacillus anthracis etc. is respectively provided with inhibitory action.
Cortex albiziae, it is sweet, it is mild-natured;Thoughts of returning home warp, Liver Channel, it has a Xie Yu that calms the nerves, and disappear carbuncle, bactericidal antiphlogistic of promoting blood circulation is antineoplastic Effect.
The tuber of dwarf lilyturf, sweet, slight bitter, cold nature.The thoughts of returning home, lung, stomach, for dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, Tianjin Wound is thirsty, Heat Diabetes, vexed insomnia, dry constipation of intestines, and modern medicine study is confirmed, the tuber of dwarf lilyturf has certain suppression to bacillus anthracis Effect.
Frutus cnidii, taste is pungent, hardship are warm in nature.Return kidney channel, eczema of vulva, married woman's pruritus vulvae, trichomonas vaginitis, eczema scabies are controlled outward Tinea, cold-dampness under band, arthritis with fixed pain caused by dampness pain in the back, impotence due to deficiency of the kidney, uterus cold infertile, modern medicine study confirms that frutus cnidii has antibacterial and diseases prevention Mechanism.
Japanese Cayratia Herb, also known as five pawl rattans, cold in nature, bitter, acid.Thoughts of returning home warp, Liver Channel, stomach, modern pharmacological research show that it has There are antiviral, anti-inflammatory, removing toxic substances, antibacterial.
Folium artemisiae argyi, taste is pungent is warm in nature.Can wind-dispelling, dehumidifying, menstruation regulating.Logical 12 warp, has Hui Yang, rationale blood, pacifies by raw, hemostasis The effects such as tire, it is also commonly used for acupuncture.For rheumatic arthritis, pruitus, irregular menstruation.
Deionized water refers to eliminate the pure water in after ionic species impurity, is usually used in food, beverage, medicine, drinks, change The industrial waters such as cosmetic.
Vaseline is a kind of oil product of grease-like, and white has mineral oil smell, without kerosene smell to yellowish-brown A kind of mineral wax, it will not be absorbed by the skin, and can form one diaphragm in skin surface, the moisture of skin is difficult Evapotranspiration Lose, and it is largely insoluble in water, can be attached on skin for a long time, therefore with good moistening effect.
In summary, disinfectant antipruritic ointment of the invention has the following advantages that:
Disinfectant antipruritic ointment of the invention is configured by clinic tests and repeated verification and formed, and meets the reason of traditional Chinese medicine By each raw material is mutually cooperateed with, and the advantage of each part is fully played.Formula used by the disinfectant antipruritic ointment In raw material, with aloe, Radix Cinnamomi Camphorae, radix bupleuri, peppermint, the coptis, greater celandine and folium artemisiae argyi as monarch drug in a prescription, stop with clearing heat and detoxicating, sterilized The function of itching, be used in the disinfectant antipruritic ointment to sterilize, antipruritic active ingredient;With golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, Radix Glycyrrhizae, the root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and Japanese Cayratia Herb are adjuvant, with antibacterial, the effect of anti-inflammatory, increase monarch drug in a prescription anti-inflammatory and stop The effect itched;With ionized water and vaseline as adjutant, the active ingredient of medicine can be allow to penetrate into skin as early as possible, make skin Moisten moisturizing.Additionally, disinfectant antipruritic ointment of the present invention is obtained using pure natural raw material, human body toxic side effect will not passed through Clinical verification, the present invention has fabulous alleviation and therapeutic effect to treatment cutaneous pruritus, it is adaptable to which the clinic of pruitus is controlled Treat and nursing popularization and application.
Specific embodiment
The following examples can help those skilled in the art that the present invention is more completely understood, but cannot be with any Mode limits the present invention.
Embodiment 1
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:4 parts of aloe, Radix Cinnamomi Camphorae 4 Part, 3 parts of radix bupleuri, 2 parts of peppermint, 3 parts of golden cypress, 2 parts of hypericum perforatum, 4 parts of betel nut, 1 part of the tuber of dwarf lilyturf, 3 parts of the coptis, 4 parts of greater celandine, Radix Glycyrrhizae 5 parts, 2 parts of the root of gansui, 3 parts of cortex albiziae, 2 parts of the tuber of dwarf lilyturf, 3 parts of frutus cnidii, 2 parts of Japanese Cayratia Herb, 5 parts of folium artemisiae argyi, 5 parts of deionized water and vaseline 3 parts.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 120 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Embodiment 2
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:17 parts of aloe, Radix Cinnamomi Camphorae 15 Part, 15 parts of radix bupleuri, 12 parts of peppermint, 10 parts of golden cypress, 9 parts of hypericum perforatum, 8 parts of betel nut, 10 parts of the tuber of dwarf lilyturf, 11 parts of the coptis, greater celandine 11 Part, 10 parts of Radix Glycyrrhizae, 8 parts of the root of gansui, 9 parts of cortex albiziae, 6 parts of the tuber of dwarf lilyturf, 7 parts of frutus cnidii, 8 parts of Japanese Cayratia Herb, 8 parts of folium artemisiae argyi, deionized water 15 14 parts of part and vaseline.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 150 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Embodiment 3
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:5 parts of aloe, Radix Cinnamomi Camphorae 5 Part, 4 parts of radix bupleuri, 4 parts of peppermint, 4 parts of golden cypress, 3 parts of hypericum perforatum, 5 parts of betel nut, 2 parts of the tuber of dwarf lilyturf, 4 parts of the coptis, 5 parts of greater celandine, Radix Glycyrrhizae 6 parts, 3 parts of the root of gansui, 4 parts of cortex albiziae, 3 parts of the tuber of dwarf lilyturf, 4 parts of frutus cnidii, 3 parts of Japanese Cayratia Herb, 4 parts of folium artemisiae argyi, 6 parts of deionized water and vaseline 5 parts.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 120 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Embodiment 4
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:15 parts of aloe, Radix Cinnamomi Camphorae 14 Part, 13 parts of radix bupleuri, 10 parts of peppermint, 9 parts of golden cypress, 8 parts of hypericum perforatum, 7 parts of betel nut, 8 parts of the tuber of dwarf lilyturf, 10 parts of the coptis, 9 parts of greater celandine, 9 parts of Radix Glycyrrhizae, 7 parts of the root of gansui, 8 parts of cortex albiziae, 5 parts of the tuber of dwarf lilyturf, 6 parts of frutus cnidii, 7 parts of Japanese Cayratia Herb, 7 parts of folium artemisiae argyi, 14 parts of deionized water and 12 parts of vaseline.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 150 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Embodiment 5
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:10 parts of aloe, Radix Cinnamomi Camphorae 12 It is part, 10 parts of radix bupleuri, 8 parts of peppermint, 7 parts of golden cypress, 6 parts of hypericum perforatum, 6 parts of betel nut, 5 parts of the tuber of dwarf lilyturf, 6 parts of the coptis, 7 parts of greater celandine, sweet 8 parts of grass, 5 parts of the root of gansui, 5 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 6 parts of Japanese Cayratia Herb, deionized water, 5 parts of folium artemisiae argyi, deionized water 8 parts and 10 parts of vaseline.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 130 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
Embodiment 6
A kind of disinfectant antipruritic ointment, is mainly obtained (every part of 1g) by following raw material:12 parts of aloe, Radix Cinnamomi Camphorae 13 It is part, 12 parts of radix bupleuri, 5 parts of peppermint, 5 parts of golden cypress, 5 parts of hypericum perforatum, 6 parts of betel nut, 4 parts of the tuber of dwarf lilyturf, 7 parts of the coptis, 8 parts of greater celandine, sweet 7 parts of grass, 4 parts of the root of gansui, 7 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 4 parts of Japanese Cayratia Herb, 5 parts of folium artemisiae argyi, 10 parts of deionized water and all 11 parts of intellectual circle.
The present invention also provides a kind of preparation method of disinfectant antipruritic ointment, and the method comprises the following steps:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, The root of gansui, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into the powder that grinder grinds to form 140 mesh;
(4) powder that step (2) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (1), is mixed with mixer and stirred Mix uniform, obtain mixture, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, i.e., Obtain the disinfectant antipruritic ointment.
A kind of clinical trial of disinfectant antipruritic ointment of the present invention
(1) testing crew physical data:
Used as the ointment for the treatment of disinfectant antipruritic, 360 clinical observations of allergic dermatitis patient are made a definite diagnosis in selection, and patient divides at random Into treatment group and control group, treatment group 180, wherein male 89, women 91, age 13-65 Sui, average age 37 years old, The course of disease -7 months 5 days, average 5 months.Control group 180, wherein male 82, women 98, age 14-66 Sui, the course of disease 5 My god -7 months, average 5 months.Two groups of courses of disease of case, degrees of symptoms are basically identical, without significant difference, with comparativity.
(2) medicament selection
Treatment group patient is applied with disinfectant antipruritic ointment of the invention, is applied at pruitus, is smeared once within 4-6 hours, 2 It is a course for the treatment of, and the usual 1-3 course for the treatment of is fully recovered, and severe patient is followed the doctor's advice the meal with wine amount of adding.Control group
(3) curative effect judging standard
(1) fully recover:Skin damaged all disappears, only pigmentation or disappearance;
(2) it is effective:Skin damaged regression more than 70%;
(3) effectively:Between skin damaged regression 30-70%;
(4) it is invalid:Skin damaged regression less than 30% or the state of an illness are more serious.
Wherein, recovery from illness, it is effective and it is effective be designated as it is effective.
(4) therapeutic effect
Refer to following statistical form
Group Treatment number Recovery from illness Significantly Effectively It is invalid Total effective rate
Treatment group 180 134 25 16 5 97.2%
Control group 180 86 35 14 45 75%
(5) conclusion
By upper table, apply in the treatment group with disinfectant antipruritic ointment of the invention, fully recover 134, notable 25, have Effect 16, total effective rate is 97.2%;Fully recovered 86 in control group, notable 35, effective 14, total effective rate is 75%.
Result above shows that treatment group is efficient apparently higher than control group, it follows that using disinfectant antipruritic of the invention Ointment has clearing heat and detoxicating, disinfectant antipruritic, and effect of bactericidal can be used to treat cutaneous pruritus, and therapeutic effect is good, takes effect Hurry up, and have no toxic side effect.It can be seen that the formula of disinfectant antipruritic ointment of the invention has certain originality, wherein between each sufficient taste medicine Mutually association increases the effect of sterilizing and itch-relieving.
Disinfectant antipruritic ointment of the invention and preparation method thereof, can not only effectively sterilized, disinfectant antipruritic, and described disappear The preparation method of the antipruritic ointment of poison is simple, easy to operate, with preferable application value.
Typical case is illustrated
Hu, female, 35 years old, patient's arm GrandTech itched, and punctation is had once scratching, and scratches and more itches, and has a strong impact on daily Life and work, once with multi-medicament, effect on driving birds is not good.After applying with 1 course for the treatment of of disinfectant antipruritic ointment of the invention, symptom is substantially delayed Solution, continues to apply with 1 course for the treatment of, all disappearances of above symptom.Follow-up is not recurred so far.
Chen, man 45 years old, the recent red swelling of the skin of patient, is itched, peels, and allergic dermatitis is diagnosed as on inspection.Tu Yong After 2 courses for the treatment of of disinfectant antipruritic ointment of the present invention, skin gradually rehabilitation, symptom is relieved, and continues to apply with after 1 course for the treatment of, the above Symptom disappears.Follow-up is not recurred so far.
Lee, female, 20 years old, patient very itched because of the allergy that eats seafood, skin, red and swollen.Apply with disinfectant antipruritic ointment 2 of the invention After the individual course for the treatment of, above symptom is disappeared, and gets well, and follow-up is not recurred so far.
Zhu, man, 55 years old, patient was very itched incomparable by bite by mosquitos leg, once uses multi-medicament, effect on driving birds is not good.Apply After 1 course for the treatment of of disinfectant antipruritic ointment of the invention, symptom takes a turn for the better, and continues to apply with after 1 course for the treatment of, recovering normal, and follow-up is so far Do not recur.
Described above is directed to the detailed description of preferably possible embodiments of the invention, but embodiment is not limited to this hair Bright patent claim, the equal change completed under the technical spirit suggested by all present invention or modification change, all should belong to Cover the scope of the claims in the present invention.

Claims (6)

1. a kind of disinfectant antipruritic ointment, it is characterised in that be mainly obtained by following raw material:Aloe 4-17 parts, cinnamomum camphora tree Root 4-15 parts, radix bupleuri 3-15 parts, peppermint 2-12 parts, golden cypress 3-10 parts, hypericum perforatum 2-9 parts, betel nut 4-8 parts, tuber of dwarf lilyturf 1-10 parts, Coptis 3-11 parts, greater celandine 4-11 parts, Radix Glycyrrhizae 5-10 parts, root of gansui 2-8 parts, cortex albiziae 3-9 parts, tuber of dwarf lilyturf 2-6 parts, frutus cnidii 3-7 Part, Japanese Cayratia Herb 2-8 parts, folium artemisiae argyi 5-8 parts, deionized water 5-15 parts and vaseline 3-14 parts.
2. a kind of disinfectant antipruritic ointment according to claim 1, it is characterised in that main by following raw material system :Aloe 5-15 parts, Radix Cinnamomi Camphorae 5-14 parts, radix bupleuri 4-13 parts, peppermint 4-10 parts, golden cypress 4-9 parts, hypericum perforatum 3-8 parts, Bin Bulky 5-7 parts, tuber of dwarf lilyturf 2-8 parts, coptis 4-10 parts, greater celandine 5-9 parts, Radix Glycyrrhizae 6-9 parts, root of gansui 3-7 parts, cortex albiziae 4-8 parts, the tuber of dwarf lilyturf 3-5 parts, frutus cnidii 4-6 parts, Japanese Cayratia Herb 3-7 parts, folium artemisiae argyi 4-7 parts, deionized water 6-14 parts and vaseline 5-12 parts.
3. a kind of disinfectant antipruritic ointment according to claim 1, it is characterised in that main by following raw material system :10 parts of aloe, 12 parts of Radix Cinnamomi Camphorae, 10 parts of radix bupleuri, 8 parts of peppermint, 7 parts of golden cypress, 6 parts of hypericum perforatum, 6 parts of betel nut, the tuber of dwarf lilyturf 5 Part, 6 parts of the coptis, 7 parts of greater celandine, 8 parts of Radix Glycyrrhizae, 5 parts of the root of gansui, 5 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 6 parts of Japanese Cayratia Herb, go 10 parts of ionized water, 5 parts of folium artemisiae argyi, 8 parts of deionized water and vaseline.
4. a kind of disinfectant antipruritic ointment according to claim 1, it is characterised in that main by following raw material system :12 parts of aloe, 13 parts of Radix Cinnamomi Camphorae, 12 parts of radix bupleuri, 5 parts of peppermint, 5 parts of golden cypress, 5 parts of hypericum perforatum, 6 parts of betel nut, the tuber of dwarf lilyturf 4 Part, 7 parts of the coptis, 8 parts of greater celandine, 7 parts of Radix Glycyrrhizae, 4 parts of the root of gansui, 7 parts of cortex albiziae, 4 parts of the tuber of dwarf lilyturf, 5 parts of frutus cnidii, 4 parts of Japanese Cayratia Herb, Chinese mugwort 11 parts of 5 parts of leaf, 10 parts of deionized water and vaseline.
5. the preparation method of a kind of disinfectant antipruritic ointment according to claim any one of 1-4, it is characterised in that including such as Lower step:
(1) above-mentioned raw materials are weighed by weight, it is standby;
(2) aloe and Japanese Cayratia Herb smashed to stir into mud standby;
(3) by the Radix Cinnamomi Camphorae, radix bupleuri, peppermint, golden cypress, hypericum perforatum, betel nut, the tuber of dwarf lilyturf, the coptis, greater celandine, Radix Glycyrrhizae, sweet Then, cortex albiziae, the tuber of dwarf lilyturf, frutus cnidii and folium artemisiae argyi are put into grinder grind into powder;
(4) powder that step (3) grinds to form is put into the aloe and Japanese Cayratia Herb mud of step (2), is mixed with mixer equal It is even, mixture is obtained, it is standby;
(5) deionized water and vaseline are added in the mixture after step (4) stirring, is stirred with mixer, obtain final product institute State disinfectant antipruritic ointment.
6. the preparation method of a kind of disinfectant antipruritic ointment according to claim 5, it is characterised in that in the step (3), The mesh number of the powder is 120-150 mesh.
CN201611077705.9A 2016-11-30 2016-11-30 A kind of disinfectant antipruritic ointment and preparation method thereof Pending CN106728820A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101321A (en) * 2021-05-06 2021-07-13 泽实润康(北京)医疗科技有限公司 External detoxification cream for treating mosquito bites and preparation process thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104830570A (en) * 2015-02-14 2015-08-12 龚俊豪 Soap for preventing skin diseases, eliminating freckles and melanin and nourishing skin and preparation method thereof
CN106138630A (en) * 2016-08-10 2016-11-23 张家港市协和医疗器械有限公司 A kind of medical disinfecting water

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104830570A (en) * 2015-02-14 2015-08-12 龚俊豪 Soap for preventing skin diseases, eliminating freckles and melanin and nourishing skin and preparation method thereof
CN106138630A (en) * 2016-08-10 2016-11-23 张家港市协和医疗器械有限公司 A kind of medical disinfecting water

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101321A (en) * 2021-05-06 2021-07-13 泽实润康(北京)医疗科技有限公司 External detoxification cream for treating mosquito bites and preparation process thereof

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