CN111704672B - 抗血浆激肽释放酶抗体 - Google Patents
抗血浆激肽释放酶抗体 Download PDFInfo
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- CN111704672B CN111704672B CN202010662282.7A CN202010662282A CN111704672B CN 111704672 B CN111704672 B CN 111704672B CN 202010662282 A CN202010662282 A CN 202010662282A CN 111704672 B CN111704672 B CN 111704672B
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Classifications
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
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- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Microbiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
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Priority Applications (1)
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| CN202010662282.7A CN111704672B (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
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| US201361791822P | 2013-03-15 | 2013-03-15 | |
| US61/791,822 | 2013-03-15 | ||
| PCT/US2014/027100 WO2014152232A2 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
| CN201480015180.9A CN105051068A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
| CN202010662282.7A CN111704672B (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201480015180.9A Division CN105051068A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
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| CN111704672A CN111704672A (zh) | 2020-09-25 |
| CN111704672B true CN111704672B (zh) | 2024-06-04 |
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| CN202010662282.7A Active CN111704672B (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
| CN201480015180.9A Pending CN105051068A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
| CN202410615191.6A Pending CN118406688A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201480015180.9A Pending CN105051068A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
| CN202410615191.6A Pending CN118406688A (zh) | 2013-03-15 | 2014-03-14 | 抗血浆激肽释放酶抗体 |
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| EP (2) | EP3594244A1 (enExample) |
| JP (2) | JP2016513682A (enExample) |
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| CN (3) | CN111704672B (enExample) |
| AU (4) | AU2014240045A1 (enExample) |
| CA (2) | CA3208188A1 (enExample) |
| HK (1) | HK1218762A1 (enExample) |
| IL (2) | IL292121B2 (enExample) |
| WO (1) | WO2014152232A2 (enExample) |
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| PL3459564T3 (pl) | 2010-01-06 | 2022-04-19 | Takeda Pharmaceutical Company Limited | Białka wiążące kalikreinę osocza |
| KR102502293B1 (ko) | 2011-01-06 | 2023-02-21 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 |
| EP3594244A1 (en) | 2013-03-15 | 2020-01-15 | Dyax Corp. | Anti-plasma kallikrein antibodies |
| KR20220107077A (ko) | 2014-01-21 | 2022-08-01 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 및 유전성 혈관부종을 치료하는 데 있어서의 이의 용도 |
| EP3122782A4 (en) | 2014-03-27 | 2017-09-13 | Dyax Corp. | Compositions and methods for treatment of diabetic macular edema |
| IL298086B2 (en) * | 2015-01-02 | 2024-11-01 | Takeda Pharmaceuticals Co | Bispecific antibodies against plasma kallikrein and factor xii |
| MX2017012423A (es) * | 2015-03-30 | 2018-01-26 | Dyax Corp | Inhibidores de calicreina plasmatica y uso de los mismos para prevenir el ataque del angioedema hereditario. |
| EP3325516B1 (en) | 2015-07-21 | 2021-12-15 | Takeda Pharmaceutical Company Limited | A monoclonal antibody inhibitor of factor xiia |
| KR20250139401A (ko) * | 2015-12-11 | 2025-09-23 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 저해제 및 유전성 혈관부종 발작을 치료하기 위한 이의 용도 |
| SG11202003479TA (en) * | 2017-10-18 | 2020-05-28 | Regenxbio Inc | Fully-human post-translationally modified antibody therapeutics |
| WO2020047352A1 (en) * | 2018-08-30 | 2020-03-05 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| EP3983449A1 (en) | 2019-06-11 | 2022-04-20 | Shire Human Genetic Therapies, Inc. | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated dysregulated plasma kallikrein |
| CA3167336A1 (en) | 2020-01-13 | 2021-07-22 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack |
| WO2021202948A2 (en) * | 2020-04-04 | 2021-10-07 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating acute respiratory distress syndrome |
| EP4263614A1 (en) | 2020-12-16 | 2023-10-25 | Takeda Pharmaceutical Company Limited | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| WO2022156798A1 (zh) * | 2021-01-25 | 2022-07-28 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| WO2022156799A1 (zh) * | 2021-01-25 | 2022-07-28 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
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| EP2970502A2 (en) | 2016-01-20 |
| US20160017055A1 (en) | 2016-01-21 |
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| US20230002509A1 (en) | 2023-01-05 |
| BR112015022282A2 (pt) | 2017-10-10 |
| KR20150132473A (ko) | 2015-11-25 |
| US11299553B2 (en) | 2022-04-12 |
| AU2019200638B2 (en) | 2021-01-28 |
| JP2020007354A (ja) | 2020-01-16 |
| JP2016513682A (ja) | 2016-05-16 |
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| US12110343B2 (en) | 2024-10-08 |
| CA3208188A1 (en) | 2014-09-25 |
| IL292121A (en) | 2022-06-01 |
| CA2906624A1 (en) | 2014-09-25 |
| IL241334A0 (en) | 2015-11-30 |
| HK1218762A1 (zh) | 2017-03-10 |
| WO2014152232A3 (en) | 2014-11-13 |
| IL292121B2 (en) | 2024-02-01 |
| AU2024219756A1 (en) | 2024-10-10 |
| US20250129182A1 (en) | 2025-04-24 |
| CN118406688A (zh) | 2024-07-30 |
| CN111704672A (zh) | 2020-09-25 |
| AU2019200638A1 (en) | 2019-02-21 |
| AU2021200144A1 (en) | 2021-03-18 |
| WO2014152232A2 (en) | 2014-09-25 |
| EP2970502A4 (en) | 2016-11-30 |
| AU2014240045A1 (en) | 2015-09-10 |
| US20190185580A1 (en) | 2019-06-20 |
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