CN111704653B - 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 - Google Patents
靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 Download PDFInfo
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Description
Claims (9)
Priority Applications (7)
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CN202311242611.2A CN117106029A (zh) | 2020-06-08 | 2020-06-08 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
CN202010515052.8A CN111704653B (zh) | 2020-06-08 | 2020-06-08 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
AU2021289870A AU2021289870A1 (en) | 2020-06-08 | 2021-05-19 | Inhibitor polypeptide compound targeting fibronectin-derived peptides and use thereof |
JP2023516640A JP2023527483A (ja) | 2020-06-08 | 2021-05-19 | フィブロネクチン由来ペプチドを標的とするインヒビターペプチド化合物及びびその用途 |
EP21821478.1A EP4163289A1 (en) | 2020-06-08 | 2021-05-19 | Inhibitor polypeptide compound targeting fibronectin-derived peptides and use thereof |
PCT/CN2021/094680 WO2021249143A1 (zh) | 2020-06-08 | 2021-05-19 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
KR1020237000148A KR20230019941A (ko) | 2020-06-08 | 2021-05-19 | 엘라스틴 유래 펩타이드를 표적하는 펩타이드 및 그 용도 |
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CN111704653A CN111704653A (zh) | 2020-09-25 |
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CN202311242611.2A Pending CN117106029A (zh) | 2020-06-08 | 2020-06-08 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
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Country Status (6)
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EP (1) | EP4163289A1 (zh) |
JP (1) | JP2023527483A (zh) |
KR (1) | KR20230019941A (zh) |
CN (2) | CN111704653B (zh) |
AU (1) | AU2021289870A1 (zh) |
WO (1) | WO2021249143A1 (zh) |
Families Citing this family (5)
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CN111704653B (zh) * | 2020-06-08 | 2023-10-03 | 深圳市图微安创科技开发有限公司 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
CN112891512A (zh) * | 2021-01-22 | 2021-06-04 | 清远市图微安创科技开发有限公司 | 多肽化合物在预防或治疗肝纤维化中的应用 |
WO2022178841A1 (zh) * | 2021-02-26 | 2022-09-01 | 深圳市图微安创科技开发有限公司 | 脂联素受体激动剂和弹性蛋白受体抑制剂联合用药预防或治疗非酒精性脂肪肝病 |
CN116768974A (zh) * | 2022-03-11 | 2023-09-19 | 中山大学 | 用于预防和/或治疗肾纤维化的多肽化合物 |
CN116008558B (zh) * | 2022-11-01 | 2024-04-02 | 吉林大学 | 细胞外基质弹性蛋白降解物在制备诊断或延缓神经退行性疾病的产品中的应用 |
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JPH0770189A (ja) * | 1993-03-03 | 1995-03-14 | Ikuo Nishimoto | アンチカプロン |
WO2012156641A1 (fr) * | 2011-05-19 | 2012-11-22 | Universite De Reims Champagne Ardenne (U.R.C.A.) | Utilisation de la kappa-elastine pour la reparation et/ou la regeneration des tissus parodontaux |
CN103890003A (zh) * | 2011-07-19 | 2014-06-25 | 特拉索斯创新公司 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
CN106170496A (zh) * | 2013-12-12 | 2016-11-30 | Umc乌得勒支控股有限公司 | 针对纤连蛋白‑eda的免疫球蛋白样分子 |
WO2018141970A1 (en) * | 2017-02-06 | 2018-08-09 | Resiliun B.V. | Interaction between c-peptides and elastin receptor, a model for understanding vascular disease |
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CN111068042A (zh) * | 2018-10-18 | 2020-04-28 | 中山大学 | 一种多肽化合物在制备治疗非酒精性肝病、特发性肺间质纤维化和动脉硬化药物中的应用 |
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ES2557938T3 (es) * | 2006-10-25 | 2016-01-29 | Janssen Biotech, Inc. | Antagonistas de resistina y su uso |
WO2015156649A1 (ko) * | 2014-04-11 | 2015-10-15 | 주식회사 젬백스앤카엘 | 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
AU2020337111A1 (en) * | 2019-08-30 | 2022-03-31 | Biotempt B.V. | Q-ER peptide |
CN111704653B (zh) * | 2020-06-08 | 2023-10-03 | 深圳市图微安创科技开发有限公司 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
-
2020
- 2020-06-08 CN CN202010515052.8A patent/CN111704653B/zh active Active
- 2020-06-08 CN CN202311242611.2A patent/CN117106029A/zh active Pending
-
2021
- 2021-05-19 KR KR1020237000148A patent/KR20230019941A/ko unknown
- 2021-05-19 JP JP2023516640A patent/JP2023527483A/ja active Pending
- 2021-05-19 WO PCT/CN2021/094680 patent/WO2021249143A1/zh unknown
- 2021-05-19 AU AU2021289870A patent/AU2021289870A1/en active Pending
- 2021-05-19 EP EP21821478.1A patent/EP4163289A1/en active Pending
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CN109810176A (zh) * | 2019-01-29 | 2019-05-28 | 中山大学 | 用于治疗非酒精性脂肪肝炎及肝纤维化的脂联素受体-1及受体-2的双激动剂肽 |
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WO2021249143A1 (zh) | 2021-12-16 |
CN117106029A (zh) | 2023-11-24 |
KR20230019941A (ko) | 2023-02-09 |
EP4163289A1 (en) | 2023-04-12 |
CN111704653A (zh) | 2020-09-25 |
AU2021289870A1 (en) | 2023-02-02 |
JP2023527483A (ja) | 2023-06-28 |
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