CN111658572A - Skin care compositions - Google Patents
Skin care compositions Download PDFInfo
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- CN111658572A CN111658572A CN201910175053.XA CN201910175053A CN111658572A CN 111658572 A CN111658572 A CN 111658572A CN 201910175053 A CN201910175053 A CN 201910175053A CN 111658572 A CN111658572 A CN 111658572A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/068—Microemulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a skin care composition, which comprises the following components in part by weight: the oil-fat emulsion comprises oil, polyglycerol di-fatty acid ester, water-soluble components, polyethylene glycol fatty acid glycerides and/or sodium surfactin. The invention also discloses the application of the skin care composition. The invention applies 'microemulsion' technology, uses specific emulsifier combination, adds high-content water phase into oil phase to form uniform and transparent 'bicontinuous phase', oil-soluble repair component and water-soluble repair component act together, grease plays roles of moistening protection, sealing, blocking and moisturizing, water-soluble active component plays roles of repairing anti-inflammatory and reducing unstable condition of skin, thereby realizing comprehensive repair of skin barrier damage while moistening skin.
Description
Technical Field
The invention relates to the field of cosmetics, in particular to a composition formula for caring skin and application thereof.
Background
Skin is improperly treated, the stratum corneum is excessively peeled off, which results in barrier damage, intercellular lipid deficiency, and skin sensitivity, and is easily stimulated by external stimuli to cause a series of skin problems, so that the barrier needs to be repaired.
Some of the products on the market aiming at barrier repair are mainly used for warming and (without preservatives and the like) moisturizing; some achieve the goal of repair by selecting or adding intact intercellular lipid components (ceramides, free fatty acids, cholesterol, etc.).
In order to achieve the purposes of moisturizing and repairing simultaneously, a common method is to add water-soluble ingredients and oil-soluble ingredients into a formula at the same time and then form an emulsion-like finished product by an emulsifier. However, for dry skin population, people in dry geographical environment and most of skin population in dry environment in autumn and winter, the moisturizing effect of the lotion is insufficient, and the cream has the defect of being too thick and heavy. Facial skin care oil has a relatively better moisturizing effect than lotion and does not feel worse than heavy face cream, so the demand of skin care oil is increasing.
Some skin care oils on the market pay attention to moisture retention, and oil such as mineral oil with strong sealing property and the like can be selected, so that the skin feel is too thick and the residual feel is too heavy. The limitation of using a pure oil system is that only oil-soluble repair ingredients can be selected and not added or only a very small amount of water-soluble ingredients can be added, so that the available raw materials are limited and do not have the effect of overall repair.
Disclosure of Invention
One of the technical problems to be solved by the invention is to provide a skin care composition which is uniform and transparent in appearance, can comprehensively repair damaged skin, has fresh skin feeling after being used and is suitable for most people.
To solve the above technical problems, the skin care composition of the present invention comprises: the oil-fat emulsion comprises oil, polyglycerol di-fatty acid ester, water-soluble components, polyethylene glycol fatty acid glycerides and/or sodium surfactin.
In the composition formula, the water-soluble component is water phase, and can be selected from water-soluble skin care components; the oil is oil phase, and oil soluble skin care component can be selected; different ingredients can provide different skin care effects; the rest components are surfactants, wherein polyglycerol di-fatty acid ester is a lipophilic surfactant with low HLB value, and polyethylene glycol fatty acid glyceride and surfactin sodium are hydrophilic surfactants with high HLB value, which have the functions of changing interfacial tension and leading the water phase and the oil phase to form bicontinuous phase microemulsion.
The content of each component in the composition is preferably as follows in parts by weight: 40-80 parts of grease, 5-20 parts of polyglycerol di-fatty acid ester, 0-20 parts of polyethylene glycol fatty acid glyceride, 0-20 parts of surfactin sodium and 5-20 parts of water-soluble components. Wherein, the polyethylene glycol fatty acid glycerides and the surfactin sodium can be mutually replaced, namely only one of the polyethylene glycol fatty acid glycerides and the surfactin sodium can be used, or the two can be used simultaneously.
The grease can be selected from one or more of jojoba oil, squalane, alkanes, mineral oil, dioctyl carbonate, C12-15 benzoate, fatty glyceride, fatty acid ester, and methyl siloxane.
The polyglycerin di-fatty acid ester may be one or more selected from polyglycerin-5 dioleate, polyglycerin-6 dioleate, polyglycerin-7 dioleate, polyglycerin-5 diisostearate, polyglycerin-6 diisostearate, and polyglycerin-7 diisostearate.
The polyethylene glycol fatty acid glycerides may be selected from one or more of PEG-6 glyceryl cocoate, PEG-7 glyceryl cocoate, PEG-8 glyceryl cocoate, PEG-6 glyceryl laurate, PEG-7 glyceryl laurate, PEG-8 glyceryl laurate, PEG-6 glyceryl myristate, PEG-7 glyceryl myristate, PEG-8 glyceryl myristate, PEG-6 caprylic/capric glycerides, PEG-7 caprylic/capric glycerides, and PEG-8 caprylic/capric glycerides.
The water-soluble component may be selected from one or more of water, polyhydric alcohol, hyaluronic acid, water-soluble plant extract, water-soluble microbial fermentation product, and water-soluble composition.
The second technical problem to be solved by the present invention is to provide the use of the above-mentioned skin care composition, which can be used for the care of the skin.
Generally, in the case that the oil phase and the water phase are not mutually soluble, the oil phase and the water phase are separated due to interfacial tension, but with the help of a surfactant with one lipophilic end and one hydrophilic end, the oil is emulsified to form a particle of oil drops to be wrapped in water to form an oil-in-water emulsion, or the water is emulsified to form a water drop to be wrapped in the oil to form a water-in-oil emulsion, which belongs to a thermodynamically unstable system, and the wrapped oil drops or water drops slowly converge with the passage of time and finally return to the separation of the oil phase and the water phase. The microemulsion is prepared by emulsifying water drops or oil drops into particles small enough under the condition of enough emulsifier, so that the water drops or the oil drops are not aggregated and layered to form a thermodynamically stable system. Wherein, the 'oil-in-water' type microemulsion is a 'continuous phase' formed outside due to high water phase content, and a 'discontinuous phase' formed inside by being divided into tiny droplets due to low oil phase content; the "water-in-oil" is contrary, the oil phase is high and is the "continuous phase", and the water phase is low and is the "discontinuous phase". The "bicontinuous phase" is a special form in the microemulsion: the contents of the water phase and the oil phase are equivalent, and under the action of a surfactant, the two phases coexist in a 'continuous phase' form to form a thermodynamic stable system.
The invention applies 'microemulsion' technology, adopts emulsifier (surfactant) combination with reasonable proportion, adds high-content water phase into oil phase, form a uniform and transparent 'bicontinuous phase' (compared with the traditional 'water-in-oil' microemulsion, although the appearance looks like a uniform oil, the addition amount of the water-soluble component can be greatly improved, thereby greatly improving the efficacy of the product), the oil-soluble repairing component and the water-soluble repairing component act together, the grease has the functions of moistening protection, sealing, blocking and moisturizing, the water-soluble active component has the functions of repairing anti-inflammatory and reducing the unstable condition of the skin, therefore, the skin is moisturized and moisturized, the comprehensive repair of the skin barrier damage is realized, the uniform and transparent oily appearance is kept, and the current situation that the repair products on the market can only select oil-soluble components or a water-oil mixed system is required to be made into emulsion is solved.
Drawings
FIG. 1 is a graph showing changes in TWEL mean values using the skin care oil of the present invention with conventional jojoba oil, squalane, split yeast lysate extract, ceramide repair components, respectively.
FIG. 2 is a graph showing the improvement of redness of skin after using the skin care oil of the present invention with conventional jojoba oil, squalane, yeast schizolysis extract, and ceramide repair components, respectively.
Detailed Description
For a more detailed understanding of the technical contents, characteristics and effects of the present invention, the technical solutions of the present invention will now be described in detail with reference to the accompanying drawings.
Example 1
The skin care oil of the embodiment comprises the following components in parts by weight:
80 parts of squalane;
5 parts of polyglycerol-6 diisostearate;
3 parts of PEG-6 glycerol cocoate;
1 part of sodium surfactin;
10 parts of water;
1 part of glycerol.
Example 2
The skin care oil of the embodiment comprises the following components in parts by weight:
30 parts of mineral oil;
20 parts of cyclohexadecyldimethyl siloxane;
20 parts of isohexadecane;
10 parts of polyglycerol-5 dioleate;
10 parts of PEG-6 glycerol cocoate;
10 parts of schizosaccharomyces cerevisiae fermentation product lysate.
Example 3
The skin care oil of the embodiment comprises the following components in parts by weight:
caprylic/capric triglyceride, 25 parts;
20 parts of isopropyl palmitate;
15 parts of hydrogenated polydecene;
5 parts of linoleic acid glyceride;
15 parts of polyglycerol-7 dioleate;
10 parts of sodium surfactin;
9.8 parts of purslane extract;
0.2 part of dipotassium glycyrrhizinate.
Example 4
The skin care oil of the embodiment comprises the following components in parts by weight:
30 parts of mineral oil;
20 parts of cyclohexadecyldimethyl siloxane;
18 parts of isohexadecane;
10 parts of polyglycerol-5 dioleate;
10 parts of PEG-6 glycerol cocoate;
10 parts of a schizosaccharomyces cerevisiae fermentation product lysate;
ceramide, 2 parts.
Example 5 comparative experiment
The skin care oil of example 4 of the present invention was compared with other commercially available repair ingredients, jojoba oil, squalane, split yeast lysis extract, ceramide, and the experimental protocol was as follows:
10 healthy skin subjects, on day 1, damaged the skin with SDS (sodium dodecyl sulfate) to damage the skin barrier of the test person. After the SDS test, the inner forearm was smeared 2 times a day for 7 days with the skin care oil of example 4 of the invention and other jojoba oil, squalane, split yeast lysate extract, ceramide repair components, respectively.
The test results (see fig. 1, fig. 2) show that: the skin care oil using the bicontinuous phase technique (labeled "bicontinuous phase" in fig. 1 and 2) of the present invention has a much more pronounced healing effect than oil alone or other single phase healing ingredients, both in terms of reduction of TWEL (transepidermal water loss) and improvement of skin redness/irritation after the skin barrier is disrupted by SDS.
Compared with the existing repair skin care products such as jojoba oil, squalane, cracked yeast cell lysis extract and ceramide on the market, the skin care oil adopts a bicontinuous phase technology, high-content water-soluble ingredients are uniformly dispersed into the oil to form uniform and transparent skin care oil containing water-soluble functional ingredients, the oil-soluble repair ingredients and the water-soluble repair ingredients act together, the oil plays roles of moistening protection, sealing, blocking and moisturizing, the water-soluble active ingredients play roles of repairing anti-inflammation and reducing skin instability, and accordingly skin barrier damage is comprehensively repaired while the skin is moistened and moisturized.
The above description is only an illustration of the implementation of the technical solution of the present invention, and various conventional modifications, additions (e.g. adding conventional functional components, essences, etc.), or similar approaches, or using raw materials with similar functions, of the above embodiments by those skilled in the art should fall into the protection scope of the present invention.
Claims (7)
1. A skin care composition characterized by comprising: the oil-fat emulsion comprises oil, polyglycerol di-fatty acid ester, water-soluble components, polyethylene glycol fatty acid glycerides and/or sodium surfactin.
2. The skin care composition according to claim 1, wherein the composition comprises the following components in parts by weight: 40-80 parts of grease, 5-20 parts of polyglycerol di-fatty acid ester, 0-20 parts of polyethylene glycol fatty acid glyceride, 0-20 parts of surfactin sodium and 5-20 parts of water-soluble components.
3. The skin care composition according to claim 1, wherein the oil is selected from one or more of jojoba oil, squalane, alkanes, mineral oil, dioctyl carbonate, C12-15 benzoate, fatty glyceride, fatty acid ester, and methyl siloxane.
4. The skin care composition according to claim 1, wherein the polyglyceryl di-fatty acid ester is selected from one or more of polyglyceryl-5 dioleate, polyglyceryl-6 dioleate, polyglyceryl-7 dioleate, polyglyceryl-5 diisostearate, polyglyceryl-6 diisostearate, polyglyceryl-7 diisostearate.
5. The skin care composition according to claim 1, wherein the polyethylene glycol fatty acid glycerides are selected from one or more of PEG-6 glyceryl cocoate, PEG-7 glyceryl cocoate, PEG-8 glyceryl cocoate, PEG-6 glyceryl laurate, PEG-7 glyceryl laurate, PEG-8 glyceryl laurate, PEG-6 glyceryl myristate, PEG-7 glyceryl myristate, PEG-8 glyceryl myristate, PEG-6 caprylic/capric glycerides, PEG-7 caprylic/capric glycerides, PEG-8 caprylic/capric glycerides.
6. The skin care composition of claim 1, wherein the water soluble component is selected from one or more of water, polyols, hyaluronic acid, water soluble plant extracts, water soluble microbial fermentation products, water soluble compositions.
7. Use of a skin care composition according to any one of claims 1 to 6 for the treatment of the skin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910175053.XA CN111658572A (en) | 2019-03-08 | 2019-03-08 | Skin care compositions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910175053.XA CN111658572A (en) | 2019-03-08 | 2019-03-08 | Skin care compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111658572A true CN111658572A (en) | 2020-09-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910175053.XA Pending CN111658572A (en) | 2019-03-08 | 2019-03-08 | Skin care compositions |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114525175A (en) * | 2021-12-31 | 2022-05-24 | 上海澄穆化妆品有限公司 | Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense |
Citations (3)
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| CN105411865A (en) * | 2015-12-11 | 2016-03-23 | 诺斯贝尔化妆品股份有限公司 | Multi-effect moisturizing microemulsion essence containing multiple vegetable oil and fat |
| CN107184429A (en) * | 2017-05-19 | 2017-09-22 | 广州蜜妆生物科技有限公司 | A kind of gentle efficiently makeup removing breast |
| CN107625660A (en) * | 2017-09-27 | 2018-01-26 | 广州环亚化妆品科技有限公司 | A kind of transparent sun-proof oleogel and preparation method thereof |
-
2019
- 2019-03-08 CN CN201910175053.XA patent/CN111658572A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105411865A (en) * | 2015-12-11 | 2016-03-23 | 诺斯贝尔化妆品股份有限公司 | Multi-effect moisturizing microemulsion essence containing multiple vegetable oil and fat |
| CN107184429A (en) * | 2017-05-19 | 2017-09-22 | 广州蜜妆生物科技有限公司 | A kind of gentle efficiently makeup removing breast |
| CN107625660A (en) * | 2017-09-27 | 2018-01-26 | 广州环亚化妆品科技有限公司 | A kind of transparent sun-proof oleogel and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 上海黛芊化妆品有限公司: ""基础研究护肤油（沪G妆网备字2018026598）"，获取网址：ftba.nmpa.gov.cn:8181/ftban/itownet/hzp_ba/fw/pz.jsp?processid=201810081127233jo1g&nid=201810081127233jo1g", 《国产非特殊用途化妆品备案服务平台》 * |
| 上海黛芊化妆品有限公司: ""基础研究护肤油（沪G妆网备字2019005257）"，获取网址：ftba.nmpa.gov.cn:8181/ftban/itownet/hzp_ba/fw/pz.jsp?processid=20190219133917a06g7&nid=20190219133917a06g7", 《国产非特殊用途化妆品备案服务平台》 * |
| 佚名: ""基础颜究修护油"，获取网址：https://www.xiaohongshu.com/discovery/item/5c6913db000000000f0102bb", 《小红书》 * |
| 张永民 译: ""微乳液在化妆品中的应用"", 《中国洗涤用品工业》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114525175A (en) * | 2021-12-31 | 2022-05-24 | 上海澄穆化妆品有限公司 | Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense |
| CN114525175B (en) * | 2021-12-31 | 2023-09-29 | 上海澄穆化妆品有限公司 | Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense |
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Application publication date: 20200915 |