CN111655841A - 用于治疗紊乱的细菌 - Google Patents

用于治疗紊乱的细菌 Download PDF

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Publication number
CN111655841A
CN111655841A CN201880055641.3A CN201880055641A CN111655841A CN 111655841 A CN111655841 A CN 111655841A CN 201880055641 A CN201880055641 A CN 201880055641A CN 111655841 A CN111655841 A CN 111655841A
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ecolin
phage
bacterium
genes
genome
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Pending
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CN201880055641.3A
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Chinese (zh)
Inventor
迪安·法尔勃
亚当·B·费希尔
文森特·M·伊莎贝拉
乔纳森·W·科图拉
大卫·卢布科维茨
保罗·F·米勒
伊夫·米列特
莎拉·伊丽莎白·罗伊
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Synchronic Operation Co
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Synchronic Operation Co
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/00021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2800/00—Nucleic acids vectors
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201880055641.3A 2017-06-21 2018-06-21 用于治疗紊乱的细菌 Pending CN111655841A (zh)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201762523225P 2017-06-21 2017-06-21
US201762523202P 2017-06-21 2017-06-21
US62/523,225 2017-06-21
US62/523,202 2017-06-21
US201762552829P 2017-08-31 2017-08-31
US201762552785P 2017-08-31 2017-08-31
US62/552,785 2017-08-31
US62/552,829 2017-08-31
US201862614213P 2018-01-05 2018-01-05
US62/614,213 2018-01-05
US201862624299P 2018-01-31 2018-01-31
US62/624,299 2018-01-31
PCT/US2018/038840 WO2018237198A1 (en) 2017-06-21 2018-06-21 BACTERIA FOR THE TREATMENT OF DISORDERS

Publications (1)

Publication Number Publication Date
CN111655841A true CN111655841A (zh) 2020-09-11

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US (2) US11879123B2 (https=)
EP (1) EP3642221A1 (https=)
JP (3) JP7358245B2 (https=)
CN (1) CN111655841A (https=)
AU (2) AU2018290278B2 (https=)
CA (1) CA3066085A1 (https=)
IL (1) IL271085B2 (https=)
WO (1) WO2018237198A1 (https=)

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CN110592057A (zh) * 2019-09-27 2019-12-20 昆明理工大学 嵌合裂解酶ILTphg和编码此酶的多核苷酸
CN111235169A (zh) * 2020-02-03 2020-06-05 昆明理工大学 一种GTP环化水解酶I基因folE及应用
CN111876400A (zh) * 2020-08-06 2020-11-03 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN112662607A (zh) * 2021-01-07 2021-04-16 上海陶宇晟生物技术有限责任公司 具备表面展示苯丙氨酸解氨酶的工程益生菌
CN116179452A (zh) * 2022-07-11 2023-05-30 山东第一医科大学(山东省医学科学院) 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用
CN116555063A (zh) * 2022-01-27 2023-08-08 中国海洋大学 动物双歧杆菌f1-7在降解苯丙氨酸中的应用
CN119875979A (zh) * 2025-01-20 2025-04-25 浙江工业大学 一种基于I型CRISPRi筛选系统构建的高产β-丙氨酸工程菌及方法

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