JP2020525012A5 - - Google Patents
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- JP2020525012A5 JP2020525012A5 JP2019571258A JP2019571258A JP2020525012A5 JP 2020525012 A5 JP2020525012 A5 JP 2020525012A5 JP 2019571258 A JP2019571258 A JP 2019571258A JP 2019571258 A JP2019571258 A JP 2019571258A JP 2020525012 A5 JP2020525012 A5 JP 2020525012A5
- Authority
- JP
- Japan
- Prior art keywords
- ecolin
- phage
- genes
- genome
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023093143A JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762523225P | 2017-06-21 | 2017-06-21 | |
| US201762523202P | 2017-06-21 | 2017-06-21 | |
| US62/523,225 | 2017-06-21 | ||
| US62/523,202 | 2017-06-21 | ||
| US201762552829P | 2017-08-31 | 2017-08-31 | |
| US201762552785P | 2017-08-31 | 2017-08-31 | |
| US62/552,785 | 2017-08-31 | ||
| US62/552,829 | 2017-08-31 | ||
| US201862614213P | 2018-01-05 | 2018-01-05 | |
| US62/614,213 | 2018-01-05 | ||
| US201862624299P | 2018-01-31 | 2018-01-31 | |
| US62/624,299 | 2018-01-31 | ||
| PCT/US2018/038840 WO2018237198A1 (en) | 2017-06-21 | 2018-06-21 | BACTERIA FOR THE TREATMENT OF DISORDERS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093143A Division JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020525012A JP2020525012A (ja) | 2020-08-27 |
| JP2020525012A5 true JP2020525012A5 (https=) | 2021-07-26 |
| JP7358245B2 JP7358245B2 (ja) | 2023-10-10 |
Family
ID=62909623
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571258A Active JP7358245B2 (ja) | 2017-06-21 | 2018-06-21 | 障害の処置のための細菌 |
| JP2023093143A Active JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A Pending JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093143A Active JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A Pending JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11879123B2 (https=) |
| EP (1) | EP3642221A1 (https=) |
| JP (3) | JP7358245B2 (https=) |
| CN (1) | CN111655841A (https=) |
| AU (2) | AU2018290278B2 (https=) |
| CA (1) | CA3066085A1 (https=) |
| IL (1) | IL271085B2 (https=) |
| WO (1) | WO2018237198A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| CN111655841A (zh) | 2017-06-21 | 2020-09-11 | 同生运营公司 | 用于治疗紊乱的细菌 |
| US11560543B2 (en) | 2017-09-14 | 2023-01-24 | University Of Massachusetts | Genetically engineered microorganisms and methods of use |
| CN108048342B (zh) * | 2017-10-26 | 2021-06-04 | 中国农业大学 | 一种耐压益生菌及其食品和制备方法 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2020223345A1 (en) | 2019-04-29 | 2020-11-05 | Antipov Eugene | Enumeration of genetically engineered microorganisms by live cell counting techniques |
| EP3962506A4 (en) | 2019-05-03 | 2022-07-13 | University Of Massachusetts | GMO MICROORGANISMS AND METHODS OF USE |
| US10920189B2 (en) * | 2019-06-21 | 2021-02-16 | Inscripta, Inc. | Genome-wide rationally-designed mutations leading to enhanced lysine production in E. coli |
| CN110592057B (zh) * | 2019-09-27 | 2022-01-28 | 昆明理工大学 | 嵌合裂解酶ILTphg和编码此酶的多核苷酸 |
| WO2021127648A1 (en) * | 2019-12-19 | 2021-06-24 | Auburn University | Microbial ester production |
| CA3167754A1 (en) * | 2020-01-14 | 2021-07-22 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| CN111235169A (zh) * | 2020-02-03 | 2020-06-05 | 昆明理工大学 | 一种GTP环化水解酶I基因folE及应用 |
| US12571020B2 (en) | 2020-02-24 | 2026-03-10 | University Of Massachusetts | Genetically engineered microorganisms that overexpress microcin-mge and methods of purification and use |
| US20230105474A1 (en) * | 2020-02-25 | 2023-04-06 | Synlogic Operating Company, Inc. | Recombinant bacteria engineered to treat diseases associated with uric acid and methods of use thereof |
| CN115298308A (zh) * | 2020-03-20 | 2022-11-04 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
| US20220031771A1 (en) * | 2020-07-31 | 2022-02-03 | Iowa State University Research Foundation, Inc. | Microencapsulated and chromosome integrated compositions for l-dopa microbiome therapy |
| CN111876400B (zh) * | 2020-08-06 | 2022-05-24 | 昆明理工大学 | 一种常温裂解酶Sly和编码此酶的多核苷酸 |
| WO2022120028A2 (en) | 2020-12-02 | 2022-06-09 | Synlogic Operating Company, Inc. | Engineered microorganisms |
| US20240316121A1 (en) * | 2020-12-31 | 2024-09-26 | Synlogic Operating Company, Inc. | Microorganisms engineered to reduce hyperphenylalaninemia |
| CN112662607A (zh) * | 2021-01-07 | 2021-04-16 | 上海陶宇晟生物技术有限责任公司 | 具备表面展示苯丙氨酸解氨酶的工程益生菌 |
| AU2022244381A1 (en) * | 2021-03-24 | 2023-10-12 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| CN113789276B (zh) * | 2021-09-15 | 2023-05-12 | 千宠堂(福建)生物科技有限公司 | 一株产β-烟酰胺单核苷酸的植物乳杆菌及其应用 |
| WO2023044479A1 (en) * | 2021-09-17 | 2023-03-23 | Synlogic Operating Company, Inc. | Methods for reducing hyperphenylalaninemia |
| CN116555063B (zh) * | 2022-01-27 | 2025-08-08 | 中国海洋大学 | 动物双歧杆菌f1-7在降解苯丙氨酸中的应用 |
| CN116179452A (zh) * | 2022-07-11 | 2023-05-30 | 山东第一医科大学(山东省医学科学院) | 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用 |
| EP4605522A1 (en) | 2022-10-17 | 2025-08-27 | Synlogic Operating Company, Inc. | Recombinant bacteria expressing phenylalanine ammonia lyase, phenylalanine transporter and l- aminoacid deaminase for reducing hyperphenylalaninemia |
| WO2025199288A1 (en) * | 2024-03-20 | 2025-09-25 | The Texas A&M University System | Programmable payload overproduction and delivery |
| CN119875979A (zh) * | 2025-01-20 | 2025-04-25 | 浙江工业大学 | 一种基于I型CRISPRi筛选系统构建的高产β-丙氨酸工程菌及方法 |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| CN1154845A (zh) | 1996-09-09 | 1997-07-23 | 首都医学院附属北京红十字朝阳医院 | 能表达活性苯丙氨酸脱氨酶的基因工程菌口服制剂 |
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| US7314974B2 (en) | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
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| GB0501540D0 (en) | 2005-01-25 | 2005-03-02 | Univ Leeds | Controlled production and delivery of biologically active agents by gut bacteria |
| EP2886658A1 (en) | 2005-03-10 | 2015-06-24 | BASF Enzymes LLC | Lyase enzymes, nucleic acids encoding them and methods for making and using them |
| EP2029739A4 (en) | 2006-06-02 | 2009-11-25 | Verenium Corp | LYASE ENZYMES, NUCLEIC ACIDS FOR THEIR CODING AND METHOD FOR THEIR PREPARATION AND USE |
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| DK2864491T3 (en) | 2012-06-22 | 2018-12-17 | Phytogene Inc | Enzymes and methods for styrene synthesis |
| CA2880620A1 (en) | 2012-07-27 | 2014-01-30 | University Of North Texas | Genetically modified probiotic for the treatment of phenylketonuria (pku) disease |
| US20150246085A1 (en) | 2012-11-01 | 2015-09-03 | The Sydney Children's Hospital Network (Randwick & Westmead) | Genetically-Modified Probiotic for Treatment of Phenylketonuria |
| JP6419082B2 (ja) | 2012-12-13 | 2018-11-07 | マサチューセッツ インスティテュート オブ テクノロジー | リコンビナーゼに基づく論理／メモリシステム |
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| KR102218930B1 (ko) | 2013-04-18 | 2021-02-23 | 코덱시스, 인코포레이티드 | 조작된 페닐알라닌 암모니아 리아제 폴리펩티드 |
| SG11201704543XA (en) | 2014-12-05 | 2017-07-28 | Synlogic Inc | Bacteria engineered to treat diseases associated with hyperammonemia |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| BR112017018656B1 (pt) | 2015-03-02 | 2021-11-30 | Synlogic, Inc | Bactéria geneticamente modificada, composição farmaceuticamente aceitável compreendendo a dita bactéria e uso da dita composição para tratar ou prevenir uma doença ou condição associada à inflamação intestinal e/ou função da barreira intestinal comprometida |
| EP3294757B1 (en) | 2015-05-13 | 2023-12-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
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| IL256216B (en) | 2015-06-10 | 2022-07-01 | Synlogic Operating Co Inc | Bacteria engineered to treat disorders involving the catabolism of a branched chain amino acid |
| WO2016210373A2 (en) | 2015-06-24 | 2016-12-29 | Synlogic, Inc. | Recombinant bacteria engineered for biosafety, pharmaceutical compositions, and methods of use thereof |
| US20170216370A1 (en) | 2015-07-31 | 2017-08-03 | Synlogic, Inc. | Bacteria engineered to treat disorders involving propionate catabolism |
| WO2017087580A1 (en) | 2015-11-16 | 2017-05-26 | Synlogic, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| WO2017123675A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic, Inc. | Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells |
| WO2017216704A1 (en) | 2016-06-13 | 2017-12-21 | Benson Hill Biosystems, Inc. | Increasing plant growth and yield by using a phenylalanine ammonia lyase sequence |
| CN111655841A (zh) | 2017-06-21 | 2020-09-11 | 同生运营公司 | 用于治疗紊乱的细菌 |
| JP2021531749A (ja) | 2018-07-12 | 2021-11-25 | コデクシス， インコーポレイテッド | 操作されたフェニルアラニンアンモニアリアーゼポリペプチド |
| CN115298308A (zh) | 2020-03-20 | 2022-11-04 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
-
2018
- 2018-06-21 CN CN201880055641.3A patent/CN111655841A/zh active Pending
- 2018-06-21 CA CA3066085A patent/CA3066085A1/en active Pending
- 2018-06-21 EP EP18740709.3A patent/EP3642221A1/en active Pending
- 2018-06-21 WO PCT/US2018/038840 patent/WO2018237198A1/en not_active Ceased
- 2018-06-21 JP JP2019571258A patent/JP7358245B2/ja active Active
- 2018-06-21 IL IL271085A patent/IL271085B2/en unknown
- 2018-06-21 US US16/621,792 patent/US11879123B2/en active Active
- 2018-06-21 AU AU2018290278A patent/AU2018290278B2/en active Active
-
2023
- 2023-03-01 AU AU2023201271A patent/AU2023201271B2/en active Active
- 2023-06-06 JP JP2023093143A patent/JP7639056B2/ja active Active
- 2023-11-17 US US18/512,389 patent/US12545886B2/en active Active
-
2025
- 2025-02-19 JP JP2025025000A patent/JP2025087727A/ja active Pending
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