CN111647073A - 一种荧光探针及其制备方法 - Google Patents
一种荧光探针及其制备方法 Download PDFInfo
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- CN111647073A CN111647073A CN202010637974.6A CN202010637974A CN111647073A CN 111647073 A CN111647073 A CN 111647073A CN 202010637974 A CN202010637974 A CN 202010637974A CN 111647073 A CN111647073 A CN 111647073A
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
- C09K2211/1037—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom with sulfur
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
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CN202010637974.6A CN111647073B (zh) | 2020-07-03 | 2020-07-03 | 一种荧光探针及其制备方法 |
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CN111647073A true CN111647073A (zh) | 2020-09-11 |
CN111647073B CN111647073B (zh) | 2022-10-18 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112250678A (zh) * | 2020-11-12 | 2021-01-22 | 中南大学 | 一种免洗型脑胶质瘤影像荧光分子探针及其制备方法与应用 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100183504A1 (en) * | 2007-06-14 | 2010-07-22 | Fanqing Frank Chen | Multimodal imaging probes for in vivo targeted and non-targeted imaging and therapeutics |
CN102037144A (zh) * | 2008-04-01 | 2011-04-27 | 生物检索技术股份有限公司 | 稳定化的核酸暗猝灭剂-荧光团探针 |
US20110129413A1 (en) * | 2009-11-06 | 2011-06-02 | Morgan Thomas T | Bioconjugation of Calcium Phosphosilicate Nanoparticles For Selective Targeting of Cells In Vivo |
US20160083791A1 (en) * | 2014-09-18 | 2016-03-24 | Pathadvantage Associated | System and method for detecting abnormalities in cervical cells |
CN106833623A (zh) * | 2017-02-17 | 2017-06-13 | 广东工业大学 | 一种荧光探针及其制备方法 |
CN108948142A (zh) * | 2018-09-04 | 2018-12-07 | 川北医学院 | 一种靶向肿瘤细胞及新生血管的荧光探针及其制备方法 |
CN110804042A (zh) * | 2019-09-20 | 2020-02-18 | 广东工业大学 | 一种喹唑啉荧光探针及其制备方法和应用 |
-
2020
- 2020-07-03 CN CN202010637974.6A patent/CN111647073B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100183504A1 (en) * | 2007-06-14 | 2010-07-22 | Fanqing Frank Chen | Multimodal imaging probes for in vivo targeted and non-targeted imaging and therapeutics |
CN102037144A (zh) * | 2008-04-01 | 2011-04-27 | 生物检索技术股份有限公司 | 稳定化的核酸暗猝灭剂-荧光团探针 |
US20110129413A1 (en) * | 2009-11-06 | 2011-06-02 | Morgan Thomas T | Bioconjugation of Calcium Phosphosilicate Nanoparticles For Selective Targeting of Cells In Vivo |
US20160083791A1 (en) * | 2014-09-18 | 2016-03-24 | Pathadvantage Associated | System and method for detecting abnormalities in cervical cells |
CN106833623A (zh) * | 2017-02-17 | 2017-06-13 | 广东工业大学 | 一种荧光探针及其制备方法 |
CN108948142A (zh) * | 2018-09-04 | 2018-12-07 | 川北医学院 | 一种靶向肿瘤细胞及新生血管的荧光探针及其制备方法 |
CN110804042A (zh) * | 2019-09-20 | 2020-02-18 | 广东工业大学 | 一种喹唑啉荧光探针及其制备方法和应用 |
Non-Patent Citations (2)
Title |
---|
HONG DING 等: "Enhanced blood-brain barrier transmigration using a novel transferrin embedded fluorescent magneto-liposome nanoformulation", 《NANOTECHNOLOGY》 * |
蒋凯 等: "苯并噻唑基荧光探针的设计、合成与应用研究进展", 《有机化学》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112250678A (zh) * | 2020-11-12 | 2021-01-22 | 中南大学 | 一种免洗型脑胶质瘤影像荧光分子探针及其制备方法与应用 |
CN112250678B (zh) * | 2020-11-12 | 2022-04-05 | 中南大学 | 一种免洗型脑胶质瘤影像荧光分子探针及其制备方法与应用 |
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CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Lu Yujing Inventor after: Huang Yibin Inventor after: Bian Wangqing Inventor after: Long Wei Inventor after: He Yan Inventor after: Zhang Kun Inventor after: Zhang Zhi Inventor after: Chen Zefeng Inventor after: Wang Yakun Inventor after: Chen Niping Inventor before: Bian Wangqing Inventor before: Huang Yibin Inventor before: Lu Yujing Inventor before: Long Wei Inventor before: He Yan Inventor before: Zhang Kun Inventor before: Zhang Zhi Inventor before: Chen Zefeng Inventor before: Wang Yakun Inventor before: Chen Niping |