CN111643527B - 转基因干细胞外泌体在制备药物或美白化妆品中的用途 - Google Patents
转基因干细胞外泌体在制备药物或美白化妆品中的用途 Download PDFInfo
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Abstract
Description
分组 | 透过Matrigel 基质胶的细胞数量 |
转基因外泌体 | 32.90±4.25 |
未转基因外泌体 | 76.14±6.51 |
空白对照 | 343.55±25.19 |
终末移植瘤体积(cm3) | 抑瘤率 | |
对照组 | 1.88±0.21 | / |
实验组1 | 0.42±0.11 | 77.66% |
实验组2 | 0.92±0.34 | 51.06% |
Claims (2)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
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CN202010709851.9A CN111643527B (zh) | 2020-07-22 | 2020-07-22 | 转基因干细胞外泌体在制备药物或美白化妆品中的用途 |
PCT/CN2021/082150 WO2022016892A1 (zh) | 2020-07-22 | 2021-03-22 | 转基因干细胞外泌体在制备药物或美白化妆品中的用途 |
US18/015,963 US11761002B2 (en) | 2020-07-22 | 2021-03-22 | Application of transgenic stem cell-derived exosome in preparing medicament or whitening cosmetic |
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CN202010709851.9A CN111643527B (zh) | 2020-07-22 | 2020-07-22 | 转基因干细胞外泌体在制备药物或美白化妆品中的用途 |
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CN111643527B true CN111643527B (zh) | 2020-12-29 |
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US (1) | US11761002B2 (zh) |
CN (1) | CN111643527B (zh) |
WO (1) | WO2022016892A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113073082A (zh) * | 2021-03-19 | 2021-07-06 | 广州远想生物科技有限公司 | TGF-β3间充质干细胞外泌体及其制备方法和应用 |
CN113304097A (zh) * | 2021-05-27 | 2021-08-27 | 上海南滨江细胞生物科技有限公司 | 一种含有干细胞外泌体的精华液及其制备方法 |
CN115531409A (zh) * | 2022-08-25 | 2022-12-30 | 顾岩 | 利用MSC-miRNA-198-exo治疗NSCLC相关恶性胸腔积液的方法 |
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US9493840B2 (en) * | 2011-10-27 | 2016-11-15 | University Of Louisville Research Foundation, Inc. | Characterizing melanoma |
CN105483081B (zh) | 2015-11-13 | 2019-09-20 | 中国人民解放军第二军医大学 | miRNA145-5p修饰脐带间充质干细胞分泌的外泌体及其制备与应用 |
CN107375944B (zh) | 2017-08-02 | 2020-07-28 | 上海市皮肤病医院 | 一种靶向抗恶性黑色素瘤的达卡巴嗪和miR-205共载外泌体及其制备方法和应用 |
CN108837142A (zh) * | 2018-07-20 | 2018-11-20 | 厦门艾赛生物科技有限公司 | 一种可修复皮肤的干细胞外泌体及其制备方法和应用 |
BR112021002321B1 (pt) * | 2018-08-08 | 2023-11-28 | Theramir Ltd | Terapia à base de microrna direcionada a cânceres positivos para lcp-1 |
TWI724521B (zh) * | 2018-08-30 | 2021-04-11 | 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 | 利用胞外囊泡診斷疾病的方法 |
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- 2021-03-22 WO PCT/CN2021/082150 patent/WO2022016892A1/zh active Application Filing
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Publication number | Publication date |
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CN111643527A (zh) | 2020-09-11 |
WO2022016892A1 (zh) | 2022-01-27 |
US11761002B2 (en) | 2023-09-19 |
US20230193270A1 (en) | 2023-06-22 |
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