CN111542316A - 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 - Google Patents

用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 Download PDF

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Publication number
CN111542316A
CN111542316A CN201880082202.1A CN201880082202A CN111542316A CN 111542316 A CN111542316 A CN 111542316A CN 201880082202 A CN201880082202 A CN 201880082202A CN 111542316 A CN111542316 A CN 111542316A
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China
Prior art keywords
acid
pharmaceutically acceptable
acceptable salt
ester
salts
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Pending
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CN201880082202.1A
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English (en)
Chinese (zh)
Inventor
X·卡普德维拉·诺尔特斯
J·萨纳古斯廷·阿奎鲁
M·I·德尔加多·加南
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Laboratory Rescuer Co
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Laboratory Rescuer Co
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Publication of CN111542316A publication Critical patent/CN111542316A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880082202.1A 2017-12-04 2018-11-29 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 Pending CN111542316A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382832.8 2017-12-04
EP17382832 2017-12-04
PCT/EP2018/082999 WO2019110416A1 (en) 2017-12-04 2018-11-29 Ophthalmic topical composition comprising dobesilic acid for treating diseases of the posterior segment of the eye

Publications (1)

Publication Number Publication Date
CN111542316A true CN111542316A (zh) 2020-08-14

Family

ID=60673756

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880082202.1A Pending CN111542316A (zh) 2017-12-04 2018-11-29 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物

Country Status (24)

Country Link
US (1) US20200390729A1 (https=)
EP (1) EP3720428B1 (https=)
JP (1) JP7846501B2 (https=)
KR (1) KR102756155B1 (https=)
CN (1) CN111542316A (https=)
AU (1) AU2018378981B2 (https=)
BR (1) BR112020011160A2 (https=)
CA (1) CA3083835A1 (https=)
CL (1) CL2020001426A1 (https=)
DK (1) DK3720428T3 (https=)
ES (1) ES2941036T3 (https=)
FI (1) FI3720428T3 (https=)
HR (1) HRP20230319T1 (https=)
HU (1) HUE061852T2 (https=)
MA (1) MA50991B1 (https=)
MX (1) MX2020005809A (https=)
MY (1) MY205498A (https=)
PH (1) PH12020550722A1 (https=)
PL (1) PL3720428T3 (https=)
PT (1) PT3720428T (https=)
SG (1) SG11202004940VA (https=)
SI (1) SI3720428T1 (https=)
WO (1) WO2019110416A1 (https=)
ZA (1) ZA202003944B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117257963A (zh) * 2023-11-02 2023-12-22 广州准优生物科技有限公司 含脐带间充质干细胞外泌体的眼用药剂及其制备方法和用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202300017430A1 (it) * 2023-08-22 2025-02-22 Service Biotech srl Soluzione oftalmica in forma di collirio contenente una isoforma umana ricombinante di manganese superossido dismutasi (rmnsod) per la cura di patologie dell’occhio
CN117643573B (zh) * 2024-01-29 2024-05-03 天津医科大学眼科医院 一种可递送药物至眼后节的纳米滴眼液及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777699A1 (en) * 2012-02-02 2014-09-17 Luis Antonio Outeirino Miguez Use of 2,5-dihydroxbencene sulfonic acid (dobesilate) for the treatment of age-related macular degeneration
EP2875811A1 (en) * 2013-11-26 2015-05-27 Luis Antonio Outeirino Miguez Use of dobesilate for treating ocular haemorrhages

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51421B1 (en) * 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
US9198886B2 (en) * 2006-08-16 2015-12-01 Pedro Cuevas Sánchez Use of 2,5-dihydroxybenzene for the treatment of ocular diseases
JP2015500213A (ja) 2011-11-30 2015-01-05 ザイジェン インフラメーション リミテッド 眼乾燥症候群を処置するためのｊｎｋシグナル伝達経路の細胞透過性ペプチド阻害剤の使用
CA2866405A1 (en) 2012-03-05 2013-09-12 Wayne State University Identification of channelopsin-2 (chop2) mutations and methods of use
RU2014140116A (ru) 2012-04-24 2016-06-10 Тромбодженикс Н.В. Антитела против pdgf-c

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777699A1 (en) * 2012-02-02 2014-09-17 Luis Antonio Outeirino Miguez Use of 2,5-dihydroxbencene sulfonic acid (dobesilate) for the treatment of age-related macular degeneration
EP2875811A1 (en) * 2013-11-26 2015-05-27 Luis Antonio Outeirino Miguez Use of dobesilate for treating ocular haemorrhages

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
PEDRO CUEVAS 等: "Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops", 《MIL MED RES》 *
PEDRO CUEVAS 等: "Topical dobesilate eye drops for ophthalmic primary pterygium", 《BMJ CASE REP》 *
张秋丽: "《眼科疾病诊治与显微手术应用 上》", 30 September 2016, 吉林科学技术出版社 *
王雨生: "《脉络膜新生血管性疾病》", 北京医科大学、中国协和医科大学联合出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117257963A (zh) * 2023-11-02 2023-12-22 广州准优生物科技有限公司 含脐带间充质干细胞外泌体的眼用药剂及其制备方法和用途

Also Published As

Publication number Publication date
SI3720428T1 (sl) 2023-05-31
CA3083835A1 (en) 2019-06-13
ES2941036T3 (es) 2023-05-16
EP3720428A1 (en) 2020-10-14
WO2019110416A1 (en) 2019-06-13
KR102756155B1 (ko) 2025-01-20
KR20200096569A (ko) 2020-08-12
ZA202003944B (en) 2022-12-21
PH12020550722A1 (en) 2021-02-15
JP7846501B2 (ja) 2026-04-15
HRP20230319T1 (hr) 2023-05-12
CL2020001426A1 (es) 2020-11-06
AU2018378981A1 (en) 2020-07-16
EP3720428B1 (en) 2023-01-11
BR112020011160A2 (pt) 2020-11-17
MX2020005809A (es) 2020-08-20
HUE061852T2 (hu) 2023-08-28
DK3720428T3 (da) 2023-03-20
US20200390729A1 (en) 2020-12-17
JP2021505554A (ja) 2021-02-18
MA50991B1 (fr) 2023-03-31
FI3720428T3 (fi) 2023-03-30
MA50991A (fr) 2020-10-14
PT3720428T (pt) 2023-04-03
PL3720428T3 (pl) 2023-05-08
MY205498A (en) 2024-10-23
SG11202004940VA (en) 2020-06-29
AU2018378981B2 (en) 2024-10-24

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