CN111542316A - 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 - Google Patents

用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 Download PDF

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Publication number
CN111542316A
CN111542316A CN201880082202.1A CN201880082202A CN111542316A CN 111542316 A CN111542316 A CN 111542316A CN 201880082202 A CN201880082202 A CN 201880082202A CN 111542316 A CN111542316 A CN 111542316A
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China
Prior art keywords
acid
pharmaceutically acceptable
acceptable salt
ester
salts
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Pending
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CN201880082202.1A
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English (en)
Chinese (zh)
Inventor
X·卡普德维拉·诺尔特斯
J·萨纳古斯廷·阿奎鲁
M·I·德尔加多·加南
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Laboratory Rescuer Co
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Laboratory Rescuer Co
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Publication of CN111542316A publication Critical patent/CN111542316A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880082202.1A 2017-12-04 2018-11-29 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物 Pending CN111542316A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382832 2017-12-04
EP17382832.8 2017-12-04
PCT/EP2018/082999 WO2019110416A1 (en) 2017-12-04 2018-11-29 Ophthalmic topical composition comprising dobesilic acid for treating diseases of the posterior segment of the eye

Publications (1)

Publication Number Publication Date
CN111542316A true CN111542316A (zh) 2020-08-14

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ID=60673756

Family Applications (1)

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CN201880082202.1A Pending CN111542316A (zh) 2017-12-04 2018-11-29 用于治疗眼睛后段疾病的包含羟苯磺酸的眼科局部组合物

Country Status (24)

Country Link
US (1) US20200390729A1 (enExample)
EP (1) EP3720428B1 (enExample)
JP (1) JP2021505554A (enExample)
KR (1) KR102756155B1 (enExample)
CN (1) CN111542316A (enExample)
AU (1) AU2018378981B2 (enExample)
BR (1) BR112020011160A2 (enExample)
CA (1) CA3083835A1 (enExample)
CL (1) CL2020001426A1 (enExample)
DK (1) DK3720428T3 (enExample)
ES (1) ES2941036T3 (enExample)
FI (1) FI3720428T3 (enExample)
HR (1) HRP20230319T1 (enExample)
HU (1) HUE061852T2 (enExample)
MA (1) MA50991B1 (enExample)
MX (1) MX2020005809A (enExample)
MY (1) MY205498A (enExample)
PH (1) PH12020550722A1 (enExample)
PL (1) PL3720428T3 (enExample)
PT (1) PT3720428T (enExample)
SG (1) SG11202004940VA (enExample)
SI (1) SI3720428T1 (enExample)
WO (1) WO2019110416A1 (enExample)
ZA (1) ZA202003944B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117257963A (zh) * 2023-11-02 2023-12-22 广州准优生物科技有限公司 含脐带间充质干细胞外泌体的眼用药剂及其制备方法和用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202300017430A1 (it) * 2023-08-22 2025-02-22 Service Biotech srl Soluzione oftalmica in forma di collirio contenente una isoforma umana ricombinante di manganese superossido dismutasi (rmnsod) per la cura di patologie dell’occhio
CN117643573B (zh) * 2024-01-29 2024-05-03 天津医科大学眼科医院 一种可递送药物至眼后节的纳米滴眼液及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777699A1 (en) * 2012-02-02 2014-09-17 Luis Antonio Outeirino Miguez Use of 2,5-dihydroxbencene sulfonic acid (dobesilate) for the treatment of age-related macular degeneration
EP2875811A1 (en) * 2013-11-26 2015-05-27 Luis Antonio Outeirino Miguez Use of dobesilate for treating ocular haemorrhages

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51421B1 (en) * 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
US9198886B2 (en) * 2006-08-16 2015-12-01 Pedro Cuevas Sánchez Use of 2,5-dihydroxybenzene for the treatment of ocular diseases
CN104023736A (zh) * 2011-11-30 2014-09-03 埃克西金炎症有限公司 Jnk信号转导途径的细胞-可渗透肽抑制剂用于治疗干眼综合征的用途
DK2822964T3 (en) * 2012-03-05 2018-12-10 Univ Wayne State IDENTIFICATION OF CHANNEL RHODOPSIN-2- (CHOP2) MUTATIONS AND METHODS OF USE
NZ700274A (en) * 2012-04-24 2016-10-28 Thrombogenics Nv Anti-pdgf-c antibodies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777699A1 (en) * 2012-02-02 2014-09-17 Luis Antonio Outeirino Miguez Use of 2,5-dihydroxbencene sulfonic acid (dobesilate) for the treatment of age-related macular degeneration
EP2875811A1 (en) * 2013-11-26 2015-05-27 Luis Antonio Outeirino Miguez Use of dobesilate for treating ocular haemorrhages

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
PEDRO CUEVAS 等: "Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops", 《MIL MED RES》 *
PEDRO CUEVAS 等: "Topical dobesilate eye drops for ophthalmic primary pterygium", 《BMJ CASE REP》 *
张秋丽: "《眼科疾病诊治与显微手术应用 上》", 30 September 2016, 吉林科学技术出版社 *
王雨生: "《脉络膜新生血管性疾病》", 北京医科大学、中国协和医科大学联合出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117257963A (zh) * 2023-11-02 2023-12-22 广州准优生物科技有限公司 含脐带间充质干细胞外泌体的眼用药剂及其制备方法和用途

Also Published As

Publication number Publication date
CA3083835A1 (en) 2019-06-13
EP3720428A1 (en) 2020-10-14
MA50991A (fr) 2020-10-14
US20200390729A1 (en) 2020-12-17
HRP20230319T1 (hr) 2023-05-12
AU2018378981B2 (en) 2024-10-24
ES2941036T3 (es) 2023-05-16
PL3720428T3 (pl) 2023-05-08
CL2020001426A1 (es) 2020-11-06
PT3720428T (pt) 2023-04-03
PH12020550722A1 (en) 2021-02-15
SI3720428T1 (sl) 2023-05-31
KR20200096569A (ko) 2020-08-12
ZA202003944B (en) 2022-12-21
MY205498A (en) 2024-10-23
DK3720428T3 (da) 2023-03-20
WO2019110416A1 (en) 2019-06-13
MA50991B1 (fr) 2023-03-31
AU2018378981A1 (en) 2020-07-16
JP2021505554A (ja) 2021-02-18
EP3720428B1 (en) 2023-01-11
SG11202004940VA (en) 2020-06-29
FI3720428T3 (fi) 2023-03-30
MX2020005809A (es) 2020-08-20
KR102756155B1 (ko) 2025-01-20
BR112020011160A2 (pt) 2020-11-17
HUE061852T2 (hu) 2023-08-28

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