CN111529447A - Preparation method of toothpaste with effects of stopping bleeding and protecting gum - Google Patents

Preparation method of toothpaste with effects of stopping bleeding and protecting gum Download PDF

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Publication number
CN111529447A
CN111529447A CN202010490780.8A CN202010490780A CN111529447A CN 111529447 A CN111529447 A CN 111529447A CN 202010490780 A CN202010490780 A CN 202010490780A CN 111529447 A CN111529447 A CN 111529447A
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Prior art keywords
extract
parts
toothpaste
vitamin
effects
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CN202010490780.8A
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Chinese (zh)
Inventor
周虎
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Yangzhou Boshi Brush Industry Co ltd
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Yangzhou Boshi Brush Industry Co ltd
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Priority to CN202010490780.8A priority Critical patent/CN111529447A/en
Publication of CN111529447A publication Critical patent/CN111529447A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the field of toothpaste production, and particularly discloses a preparation method of toothpaste with the effects of stopping bleeding and protecting gum, which comprises the following raw materials in parts by weight: 3-5 parts of compound vitamin, 6-10 parts of honeysuckle extract, 4-7 parts of mint extract, 2-4 parts of aloe extract, 2-4 parts of holly bark extract, 1-3 parts of bamboo leaf extract, and proper amounts of essence, polyethylene glycol, an auxiliary A and an auxiliary B. According to the invention, the honeysuckle extract, the mint extract, the aloe extract, the holly bark extract and the bamboo leaf extract are added into the raw materials, so that the Chinese medicinal composition has better effects of clearing heat and purging fire, inhibiting bacteria and killing bacteria, stopping bleeding and protecting gum, can relieve and alleviate oral problems such as redness and swelling of gum, bleeding and the like, effectively reduces the gingivitis index, and plays roles of preventing, controlling and relieving gingivitis; meanwhile, the honeysuckle, the mint, the aloe and the bamboo leaves are mixed, so that the toothpaste has special fragrance, enhances the mouthfeel of the toothpaste and freshes breath; the addition of the compound vitamin can effectively protect the oral mucosa and has good repairing and protecting effects.

Description

Preparation method of toothpaste with effects of stopping bleeding and protecting gum
Technical Field
The invention relates to the field of toothpaste production, in particular to a preparation method of toothpaste with the effects of stopping bleeding and protecting gum.
Background
According to the national oral health epidemiological survey report published by the ministry of health council of China, the detection rate of gingival bleeding in oral health of middle-aged people is continuously increased, the proportion of gingival inflammation of the people is gradually increased, and the main clinical manifestations of gingival inflammation are gingival swelling and pain, bleeding and halitosis, which cause gingival atrophy and finally lead to tooth loss. In severe cases, it can also affect and drive a series of health problems of the whole body. The periodontal health condition is more and more emphasized by consumers and people in all fields, and the toothpaste with efficacy aiming at the gingival inflammation is used to scientifically clean and care the oral cavity and has very important significance for early and timely prevention and control of periodontal diseases.
Honeysuckle is also known as honeysuckle flower, is known as a good medicine for clearing heat and removing toxicity from old times, has sweet, cold and fragrant flavor, clears heat without hurting stomach due to sweet cold, and can eliminate pathogenic factors after the fragrance is permeated. The honeysuckle can disperse wind-heat and clear away blood toxin, and has obvious effect on various heat diseases such as fever, eruption, macula, sore and carbuncle due to heat toxin, sore throat and the like.
Mint is one of the common Chinese traditional medicines. It is a pungent and cool sweating antipyretic, and can be used for treating influenza, headache, conjunctival congestion, fever, and swelling and pain of throat and gum.
Aloe has purgative, hemostatic, anti-infectious and anti-tumor effects. In ancient medical records such as Ben Jing He Jie Yuan, Aloe is used for treating infantile malnutrition with heat accumulation. Aloe contains aloe-emodin, and has effect in resisting pathogenic microorganism. According to the reports of foreign documents, the aloe extract can promote the injured tissues, and also has the pharmacological actions of detoxifying, reducing blood fat, resisting atherosclerosis, promoting the recovery of hematopoietic function of experimental anemia and the like.
The holly is a common garden ornamental tree species in China; the wood is tough and tough, is used as a raw material for fine workers, and is used for manufacturing toys, sculptures, tool handles, brush backs, wooden combs and the like; the bark and the seeds are used as medicinal agents, are strong agents, have strong bacteriostatic and bactericidal effects, and have the effects of cooling blood, removing toxicity, stopping bleeding and stopping leukorrhagia.
The folium Bambusae extract is leaf of Bambusa vulgaris of Gramineae, and is distributed in provinces of Yangtze river basin. The bamboo leaf extract can be collected at any time, and fresh products are preferably used for clearing heat and purging fire; it is good at clearing heart fire, relieving restlessness, clearing stomach, promoting fluid production and quenching thirst.
Disclosure of Invention
The invention aims to provide a preparation method of toothpaste with the effects of stopping bleeding and protecting gum, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a preparation method of toothpaste with the effects of stopping bleeding and protecting gum comprises the following specific steps:
s1: preparing raw materials according to the following weight: 3-5 parts of compound vitamin, 6-10 parts of honeysuckle extract, 4-7 parts of mint extract, 2-4 parts of aloe extract, 2-4 parts of holly bark extract, 1-3 parts of bamboo leaf extract, and proper amounts of essence, polyethylene glycol, an auxiliary A and an auxiliary B;
s2: grinding the compound vitamins into powder, mixing with aloe extract, holly bark extract and bamboo leaf extract, dissolving in essence, and stirring to obtain mixture A;
s3: dissolving the honeysuckle extract and the mint extract in polyethylene glycol, and fully stirring to obtain a mixture B;
s4: mixing the mixture A and the auxiliary agent A, mixing the mixture B and the auxiliary agent B, adding into paste-making equipment together, stirring and grinding for 30-50min, and simultaneously vacuum degassing to obtain toothpaste body.
Preferably, the compound vitamin is a compound of vitamin B2, vitamin B6, vitamin A5, vitamin C and vitamin E, and the mixture ratio of each component is as follows: vitamin B2: 10-15 parts, vitamin B6: 1-1.5 parts, vitamin A: 50.2-0.5 parts of vitamin C: 3-5 parts of vitamin E: 10-20 parts.
Preferably, the auxiliary agent A is an abrasive agent, a foaming agent and a binding agent, and the auxiliary agent B is a preservative, sorbitol and a sweetening agent.
Preferably, the honeysuckle extract, the mint extract, the holly bark extract and the bamboo leaf extract are respectively concentrated solutions obtained by extracting honeysuckle, mint, holly bark and bamboo leaves by a distillation method.
Preferably, the aloe extract is obtained by collecting leaf juice of aloe leaves, putting into a pot, decocting into thick paste, cooling and solidifying.
Preferably, in step S4, the vacuum degree of vacuum degassing is greater than 0.096MPa, and the degassing and stirring time is 15-30 min.
Preferably, in step S4, after the mixed material is added to the paste making device, a mixed solution of essence and polyethylene glycol is added to adjust the viscosity of the material, and the ratio of the essence to the polyethylene glycol in the mixed solution is 1-3: 5-10.
Compared with the prior art, the invention has the beneficial effects that:
according to the invention, the honeysuckle extract, the mint extract, the aloe extract, the holly bark extract and the bamboo leaf extract are added into the raw materials, so that the Chinese medicinal composition has better effects of clearing heat and purging fire, inhibiting bacteria and killing bacteria, stopping bleeding and protecting gum, can relieve and alleviate oral problems such as redness and swelling of gum, bleeding and the like, effectively reduces the gingivitis index, and plays roles of preventing, controlling and relieving gingivitis; meanwhile, the honeysuckle, the mint, the aloe and the bamboo leaves are mixed, so that the toothpaste has special fragrance, enhances the mouthfeel of the toothpaste and freshes breath; the addition of the compound vitamin can improve or cure rough skin, angular stomatitis, glossitis, fatty dermatitis, cheilitis, oral ulcer, gingival bleeding and other diseases caused by vitamin deficiency; simultaneously, the vitamins are directly contacted with the oral mucosa through tooth brushing and are easily absorbed by the oral cells, so that the injured cells are recovered, the healing of the sore is accelerated, the oral mucosa can be effectively protected, and the repairing and protecting effects are good.
Detailed Description
The invention provides a technical scheme that: a preparation method of toothpaste with the effects of stopping bleeding and protecting gum comprises the following specific steps:
s1: preparing raw materials according to the following weight: 3-5 parts of compound vitamin, 6-10 parts of honeysuckle extract, 4-7 parts of mint extract, 2-4 parts of aloe extract, 2-4 parts of holly bark extract, 1-3 parts of bamboo leaf extract, and proper amounts of essence, polyethylene glycol, an auxiliary A and an auxiliary B;
s2: grinding the compound vitamins into powder, mixing with aloe extract, holly bark extract and bamboo leaf extract, dissolving in essence, and stirring to obtain mixture A;
s3: dissolving the honeysuckle extract and the mint extract in polyethylene glycol, and fully stirring to obtain a mixture B;
s4: mixing the mixture A and the auxiliary agent A, mixing the mixture B and the auxiliary agent B, adding into paste-making equipment together, stirring and grinding for 30-50min, and simultaneously vacuum degassing to obtain toothpaste body.
Further, the compound vitamin is a compound of vitamin B2, vitamin B6, vitamin A5, vitamin C and vitamin E, and the mixture ratio of the components is as follows: vitamin B2: 10-15 parts, vitamin B6: 1-1.5 parts, vitamin A: 50.2-0.5 parts of vitamin C: 3-5 parts of vitamin E: 10-20 parts.
Furthermore, the auxiliary agent A is an abrasive agent, a foaming agent and an adhesive, and the auxiliary agent B is a preservative, sorbitol and a sweetening agent.
Further, the honeysuckle extract, the mint extract, the holly bark extract and the bamboo leaf extract are respectively concentrated solutions obtained by extracting honeysuckle, mint, holly bark and bamboo leaves by a distillation method.
Further, the aloe extract is obtained by collecting leaf juice of aloe leaves, putting the leaf juice into a pot, decocting the leaf juice into thick paste, and cooling and solidifying the thick paste.
Further, in step S4, the vacuum degree of vacuum degassing is greater than 0.096MPa, and the degassing and stirring time is 15-30 min.
Further, in step S4, after the mixed material is added to the paste making device, a mixed solution of essence and polyethylene glycol is added to adjust the viscosity of the material, and the ratio of the essence to the polyethylene glycol in the mixed solution is 1-3: 5-10.
According to the invention, the honeysuckle extract, the mint extract, the aloe extract, the holly bark extract and the bamboo leaf extract are added into the raw materials, so that the Chinese medicinal composition has better effects of clearing heat and purging fire, inhibiting bacteria and killing bacteria, stopping bleeding and protecting gum, can relieve and alleviate oral problems such as redness and swelling of gum, bleeding and the like, effectively reduces the gingivitis index, and plays roles of preventing, controlling and relieving gingivitis; meanwhile, the honeysuckle, the mint, the aloe and the bamboo leaves are mixed, so that the toothpaste has special fragrance, enhances the mouthfeel of the toothpaste and freshes breath; the addition of the compound vitamin can improve or cure rough skin, angular stomatitis, glossitis, fatty dermatitis, cheilitis, oral ulcer, gingival bleeding and other diseases caused by vitamin deficiency; simultaneously, the vitamins are directly contacted with the oral mucosa through tooth brushing and are easily absorbed by the oral cells, so that the injured cells are recovered, the healing of the sore is accelerated, the oral mucosa can be effectively protected, and the repairing and protecting effects are good.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. A preparation method of toothpaste with the effects of stopping bleeding and protecting gum is characterized by comprising the following specific steps:
s1: preparing raw materials according to the following weight: 3-5 parts of compound vitamin, 6-10 parts of honeysuckle extract, 4-7 parts of mint extract, 2-4 parts of aloe extract, 2-4 parts of holly bark extract, 1-3 parts of bamboo leaf extract, and proper amounts of essence, polyethylene glycol, an auxiliary A and an auxiliary B;
s2: grinding the compound vitamins into powder, mixing with aloe extract, holly bark extract and bamboo leaf extract, dissolving in essence, and stirring to obtain mixture A;
s3: dissolving the honeysuckle extract and the mint extract in polyethylene glycol, and fully stirring to obtain a mixture B;
s4: mixing the mixture A and the auxiliary agent A, mixing the mixture B and the auxiliary agent B, adding into paste-making equipment together, stirring and grinding for 30-50min, and simultaneously vacuum degassing to obtain toothpaste body.
2. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: the compound vitamin is a compound of vitamin B2, vitamin B6, vitamin A5, vitamin C and vitamin E, and the mixture ratio of the components is as follows: vitamin B2: 10-15 parts, vitamin B6: 1-1.5 parts, vitamin A: 50.2-0.5 parts of vitamin C: 3-5 parts of vitamin E: 10-20 parts.
3. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: the auxiliary agent A is an abrasive agent, a foaming agent and an adhesive, and the auxiliary agent B is a preservative, sorbitol and a sweetening agent.
4. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: the honeysuckle extract, the mint extract, the holly bark extract and the bamboo leaf extract are respectively concentrated solutions obtained by extracting honeysuckle, mint, holly bark and bamboo leaves by a distillation method.
5. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: the aloe extract is obtained by collecting leaf juice of aloe leaves, putting into a pot, decocting into thick paste, and cooling and solidifying.
6. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: in step S4, the vacuum degree of vacuum degassing is greater than 0.096Mpa, and the degassing and stirring time is 15-30 min.
7. The preparation method of the toothpaste with the effects of stopping bleeding and protecting the gum as claimed in claim 1, wherein the toothpaste comprises the following components in percentage by weight: in the step S4, after the mixed material is added into the paste making equipment, the mixed liquid of essence and polyethylene glycol is added to adjust the viscosity of the material, and the ratio of the essence to the polyethylene glycol in the mixed liquid is 1-3: 5-10.
CN202010490780.8A 2020-06-02 2020-06-02 Preparation method of toothpaste with effects of stopping bleeding and protecting gum Pending CN111529447A (en)

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CN202010490780.8A CN111529447A (en) 2020-06-02 2020-06-02 Preparation method of toothpaste with effects of stopping bleeding and protecting gum

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CN202010490780.8A CN111529447A (en) 2020-06-02 2020-06-02 Preparation method of toothpaste with effects of stopping bleeding and protecting gum

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102846498A (en) * 2011-06-28 2013-01-02 黑龙江省麒麟工贸公司 Preparation method for mouth wash from bamboo leaf extract
CN108403544A (en) * 2018-03-26 2018-08-17 长沙循源医学科技有限公司 A kind of Pediatric Oral Emergency care composition and preparation method thereof
CN109893496A (en) * 2017-12-08 2019-06-18 张立山 A kind of antibacterial toothpaste containing seaweed essence

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102846498A (en) * 2011-06-28 2013-01-02 黑龙江省麒麟工贸公司 Preparation method for mouth wash from bamboo leaf extract
CN109893496A (en) * 2017-12-08 2019-06-18 张立山 A kind of antibacterial toothpaste containing seaweed essence
CN108403544A (en) * 2018-03-26 2018-08-17 长沙循源医学科技有限公司 A kind of Pediatric Oral Emergency care composition and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王玉忠: "《实用化学品配方手册》", 31 March 2009, 四川科学技术出版社 *

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Application publication date: 20200814