CN111514060B

CN111514060B - Liquid foundation with moisturizing and anti-aging effects

Info

Publication number: CN111514060B
Application number: CN202010355047.5A
Authority: CN
Inventors: 刘俚扬; 任巍
Original assignee: Zhicui Youpin Tianjin Biotechnology Co ltd
Current assignee: Zhicui Youpin Tianjin Biotechnology Co ltd
Priority date: 2020-04-29
Filing date: 2020-04-29
Publication date: 2023-03-24
Anticipated expiration: 2040-04-29
Also published as: CN111514060A

Abstract

The invention relates to a foundation liquid with moisturizing and anti-aging effects, which comprises the following components: phase A: 1-5% of PEG-10 polydimethylsiloxane; 3-30% of cyclopentasiloxane; 0.1-1% of tocopherol acetate; 3-15% of titanium dioxide; 0.1 to 5 percent of pearl powder; 0.1-2% of iron oxide; 0.5-10% of hyaluronic acid microspheres; ceramide 3.01-1%; 0.2 to 2 percent of bentonite; phase B: 0.1-5% of hydrolyzed pea protein; 2-10% of glycerol; 0.02-1% of ethylhexyl glycerol; 0.1 to 1 percent of phenoxyethanol; the balance of pure water. The invention provides a multi-effect foundation composition, which is characterized in that hyaluronic acid microspheres, hydrolyzed vegetable protein, ceramide and other components are added into foundation liquid, so that the functions of moisturizing, anti-aging, repairing, concealing flaws and repairing the appearance are really integrated, the skin care steps can be simplified, the skin care steps are simplified for consumers, and the skin care time is saved.

Description

Foundation make-up liquid with moisturizing and anti-aging effects

Technical Field

The invention belongs to the field of cosmetic processing, relates to a foundation fluid processing technology, and particularly relates to a foundation fluid with moisturizing and anti-aging effects.

Background

Aging is a progressive, irreversible degeneration of physiological structure and function that occurs from the maturation phase of an organism as it ages. The aging of the skin is classified into endogenous aging and exogenous aging, wherein the endogenous aging refers to natural aging which appears along with the increase of the age and is characterized in that the skin has fine wrinkles, reduced elasticity, loose skin and the like. The most prominent cause of extrinsic aging is photoaging due to sun exposure. Skin discoloration manifested as wrinkles, loose skin, roughness, yellowish or grayish yellow, telangiectasia, formation of pigmented spots, and the like.

The foundation liquid is light and thin in texture, easy to smear and less greasy in feeling, can well adjust the skin color, improve the facial texture, cover flaws, has natural skin color immediately after makeup, and is a quick skin-decorating cosmetic popular with current consumers. The foundation liquid forms a smooth covering layer on the surface of the skin, is used for covering or masking certain facial flaws such as freckles, acnes, scars and the like, adjusts the texture, the color and the luster of the skin, plays a role in homogenizing the skin color, enables the skin color to look natural and close, has smooth and tender feeling, and has the characteristics of easy smearing, uniform distribution and natural make-up.

However, the current foundation liquid products have single functions, most of the foundation liquid products are only used for covering and modifying the skin, some foundation bases with poor quality cannot be used for covering and modifying the skin, the skin cannot be air-tight after the foundation bases are used, pores are easy to block, and although some anti-aging ingredients, such as ascorbic acid derivatives, collagen, plant extracts and the like, are added into some brand foundation liquids, the effect is limited, and the requirement of consumers for improving the skin for a long time cannot be met.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide a multi-effect foundation make-up composition, wherein the foundation liquid is added with components such as coating hyaluronic acid, hydrolyzed vegetable protein, ceramide and the like, so that the effects of moisturizing, resisting aging, repairing, covering blemishes and repairing the face are really integrated, the multi-effect function of one bottle is achieved, the skin care steps are simplified for consumers in the environment with faster and faster modern rhythm, and the skin care time is saved.

The technical problem to be solved by the invention is realized by adopting the following technical scheme:

a foundation liquid with moisturizing and anti-aging effects comprises:

phase A:

1-5% of PEG-10 polydimethylsiloxane;

3-30% of cyclopentasiloxane;

0.1-1% of tocopherol acetate;

3-15% of titanium dioxide;

0.1 to 5 percent of pearl powder;

0.1-2% of iron oxide, wherein the iron oxide comprises one or more of iron oxide red, iron oxide yellow and iron oxide black, the iron oxide red is a necessary additive component, and the iron oxide yellow and the iron oxide black are added according to the color requirement;

0.5-10% of hyaluronic acid microspheres (including more than or equal to 0.1% of sodium hyaluronate, 50-100% of hydrogenated polyisobutene, 1-20% of trihydroxy stearin and more than or equal to 0.01% of glucomannan);

30.01-1% of ceramide;

0.2 to 2 percent of bentonite.

Phase B:

0.1-5% of hydrolyzed pea protein;

2-10% of glycerol;

0.02-1% of ethylhexyl glycerol;

0.1 to 1 percent of phenoxyethanol;

the balance of pure water.

The preparation method of the foundation liquid with the effects of moisturizing and resisting aging comprises the following steps:

1. weighing the phase A material, uniformly mixing, and homogenizing to completely disperse all components;

2. weighing the phase B material, and uniformly stirring;

3. slowly pouring the phase B into the phase A under stirring, homogenizing and emulsifying for 2-8 min to completely disperse the materials to obtain the foundation solution, wherein the homogenizing and emulsifying condition is vacuum degree of-0.05 mpa.

The preparation method of the hyaluronic acid microspheres comprises the following steps:

(1) Reaction: 1% of sodium hyaluronate with a molecular weight of 5 ten thousand was added to 1, 4-butanediol diglycidyl ether: 0.25mol/L sodium hydroxide solution =1, stirring uniformly, heating to 50-60 ℃, reacting for 4-72h, and cooling to 25 ℃.

(2) Neutralizing: after the reaction in the above step is finished, a proper amount of hydrochloric acid solution is dripped to adjust the pH value to be about neutral 7.

(3) And (3) purification: adding a proper amount of 0.2mol/L phosphate buffer solution, and stirring and purifying for 2 hours at room temperature.

(4) And (3) freeze drying: sieving by a 80-mesh filter screen, pre-freezing the intercepted substances at the temperature of minus 20 ℃ for 1h, at the temperature of minus 40 ℃, carrying out sublimation drying at the vacuum degree of 80-100 Pa for 2h, and carrying out resolution drying at the temperature of 45 ℃ and the vacuum degree of 50-60 Pa for 2h to obtain the semi-finished product of the hyaluronic acid microspheres.

(5) And (3) reprocessing: mixing the filtered product with hydrogenated polyisobutene, trihydroxystearin and glucomannan according to a certain proportion, and stirring uniformly to obtain a finished product.

The process steps of the hydrolyzed pea protein are as follows:

(1) Pretreatment: accurately weighing pea protein powder according to the process, adding the pea protein powder into purified water, stirring for 10min to prepare a pea protein solution with the concentration of 2-4%, simultaneously adjusting the pH value to 6-8.5 by using 0.1mol/LNaOH solution, heating the solution to 85 ℃, and keeping the temperature constant for 15 min.

(2) Enzymolysis: papain and bromelain are added into the pea protein solution, the enzyme adding amount is 3500-6000u/g, and the enzymolysis treatment time is 3-12 h. The pH was kept constant during the enzymatic hydrolysis with 0.1mol/L NaOH solution.

(3) Enzyme deactivation: the enzymolysis solution is rapidly heated to 90 ℃ and kept for 20min, and then cooled to room temperature.

(4) Centrifugal separation: and setting the centrifugal machine at 2000r/min, and centrifuging for 15min to obtain upper-layer liquid.

(5) And (3) filtering: filtering the liquid in the step (4) by using a 200-mesh filter screen, and then performing ultrafiltration on the polypeptide solution with the molecular weight cutoff of less than 1000.

The invention has the advantages and positive effects that:

1. the hyaluronic acid microspheres are formed on the basis of dehydration, can quickly permeate into the epidermis layer of the skin and can be filled with water to expand after entering the skin. As shown in figure 1, during the water filling process, the volume of the microspheres is increased, and the microspheres have strong water holding capacity. Can change the skin in a short time and smooth wrinkles in the deep layer of the skin. Improvement in the depth of the skin is generally found after two months, with the appearance changing much more rapidly than the improvement in the depth. The hyaluronic acid microspheres have the water holding property, so that the hyaluronic acid microspheres have the function of smoothing fine lines of canthus after being used for one hour. The effect of smoothing deep wrinkles of the hyaluronic acid microspheres is very excellent, and even the same effect as that of wrinkle removal by injection can be achieved.

2. The hyaluronic acid microspheres are derived from hyaluronic acid with high water-holding capacity, can quickly permeate into the bottom layer of the skin, efficiently absorb water and lock water, can increase the skin water saturation degree, can smooth fine lines caused by years and external injuries, and particularly has an obvious effect of fading deep wrinkles. The hyaluronic acid microsphere uses a unique preparation process, 1 percent of sodium hyaluronate with the molecular weight of 5 ten thousand is added with 1, 4-butanediol diglycidyl ether: 0.25mol/L sodium hydroxide solution =1, stirring uniformly, heating to 50-60 ℃, reacting for 4-72h, cooling to 25 ℃, and enabling the particle size distribution of the hyaluronic acid microspheres to be uniform, so that the utilization rate of the hyaluronic acid microspheres is greatly improved, and the absorption effect is good.

3. The hyaluronic acid gel microspheres in the prior art are usually water-soluble, while the hyaluronic acid microspheres prepared in the invention are dehydrated by using a freeze-drying filtration technology and dissolved in an oil phase to prepare a water-in-oil foundation solution, and the hyaluronic acid microspheres are dissolved in the oil phase and the oil phase wraps the water phase, so that the hyaluronic acid cannot enter the water phase, the activity of the hyaluronic acid can be well maintained, and the hyaluronic acid gel microspheres can absorb water and swell to achieve the effect of instant filling and anti-wrinkle after entering human skin.

4. Ceramide 3 is the main component of lipoid body among human stratum corneum cells, has good affinity to skin, can strengthen the stratum corneum of epidermis, helps to repair and protect damaged skin, helps to update the natural protective layer of the skin, and prevents the skin from being stimulated by external force; meanwhile, the ceramide 3 can prevent water loss, permanently moisten the skin, has a good moisturizing function, and is particularly suitable for sensitive and dry skins.

5. Hydrolyzing pea protein: pea protein is rich in 8 amino acids essential to human body, and the composition (in mg) of 100g of pea protein is as follows: lysine 1398; isoleucine 831; leucine 1440; methionine 218; phenylalanine 938; threonine 719; tryptophan 197; valine 942. The proportion of 8 human essential amino acids in pea protein is very close to the FAO/WHO recommended model except for slightly lower methionine. The most readily absorbable form of nutrients by the human body is polypeptides. The polypeptide molecule size is between that of amino acid and protein, the skin absorption of macromolecular protein is difficult, and the skin absorption efficiency of micromolecular amino acid is low.

6. The hydrolyzed pea protein of the invention ensures that the pea protein is decomposed into 3-6 peptides by a biological enzymolysis process, and the polypeptide consisting of 3-6 amino acids can be effectively absorbed by skin in the form of a group and becomes a necessary component for synthesizing cell protein after entering the skin. With age, collagen in the dermal connective tissue gradually decreases, resulting in the generation of wrinkles. Activate the skin to synthesize more collagen, and the facial wrinkles can be obviously improved. The hydrolyzed pea protein has obvious promotion effect on the synthesis of collagen I, collagen III, elastin and pre-elastin in skin, and is helpful for improving the strength and elasticity of skin.

7. The pearl powder of the present invention is nacre formed by depositing an alternate monolayer structure of aragonite and conchiolin around the nucleus, and the aragonite layer is 0.30-0.60mm thick and consists of highly lamellar crystalline calcium carbonate. Conchiolin is a natural organic substance and is composed of mucopolysaccharides forming a crystallized layer. The microelements can promote the increase of SOD quantity, enhance activity, scavenge free radicals, and improve skin color; the oil control is realized, the pearl powder has extremely fine particle size, so the surface area is very large, the adsorption capacity is better, and redundant grease can be adsorbed on the pearl powder. Meanwhile, the skin care product has an astringent effect, and can control the secretion of grease to make the skin dry and clean; the pearl powder has good pore deep cleaning capability and very strong adsorption capability, can absorb dead skin and deep dirt of the pores, and has the cleaning effect.

7. The invention provides a multi-effect foundation composition, wherein components such as coating hyaluronic acid, hydrolyzed vegetable protein, ceramide, pearl powder and the like are added into foundation liquid, and the synergistic effect is achieved by utilizing the hydrolyzed pea protein, hyaluronic acid microspheres, ceramide and pearl powder, so that the moisturizing and wrinkle removing effects of the foundation liquid can be obviously improved, the multiple effects of moisturizing, resisting aging, repairing, covering blemishes and repairing the face can be really integrated, the skin care step can be simplified, the foundation liquid can be uniformly coated on the face after the face is cleaned, the multi-effect function of one bottle can be achieved, the skin care step can be simplified for consumers under the environment with increasingly fast modern rhythm, and the skin care time can be saved.

Drawings

FIG. 1 is an electron microscope image of hyaluronic acid microspheres entering into dermis layer of skin;

FIG. 2 is a graph comparing the increase in skin moisture levels of the subjects of examples and comparative examples;

FIG. 3 is a graph comparing the increase in skin elasticity for the subjects of the examples and comparative examples;

FIG. 4 is a graph comparing skin texture and crow's feet for each of the examples and comparative subjects;

FIG. 5 is a graph comparing cheek effects before and after use by a subject;

FIG. 6 is a comparison of periocular effects before and after use by a subject;

fig. 7 is a graph comparing the effect of the canthus before and after the use of the subject.

Detailed Description

The present invention is further illustrated by the following specific examples, which are intended to be illustrative, not limiting and are not intended to limit the scope of the invention.

Comparative example 1

Because the composition is water-in-oil foundation fluid, the functional components in the composition are added in the same proportion in comparative example 1, the base oil and the humectant are also added in the same proportion, and only the emulsifier is different, the oil-in-water emulsion is prepared, and the effects between the composition and the emulsion are compared

The formulation of the oil-in-water emulsion is as follows:

phase A:

cyclopenta polydimethylsiloxane 18%

Tocopherol acetate 0.5%

Hyaluronic acid microspheres 0.5%

Ceramide 3.01%

1% of pearl powder

Cetearyl glucoside 0.5%

Cetearyl alcohol 1.5%

Phase B:

6 percent of glycerin

0.3 percent of hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer

And C phase:

ethylhexyl glycerin 0.2%

0.4 percent of phenoxyethanol

Hydrolyzed pea protein

The preparation method comprises the following steps:

1. weighing the phase A material, heating to 80-85 ℃ to completely dissolve the solid;

2. weighing the material of the phase B, heating and stirring to 80-85 ℃, homogenizing until all the material is completely dispersed, adding the phase A in the step 1, stirring and homogenizing until the material is completely dispersed, and cooling;

3. cooling to below 45 ℃, adding the phase C and stirring evenly to obtain the emulsion of the comparative example 1.

Comparative example 4

The hyaluronic acid microspheres of comparative example 1 were removed.

Comparative example 5

Ceramide 3 and pearl powder in comparative example 1 were removed.

Comparative example 6

The hydrolysed pea proteins of comparative example 1 were removed.

Description of the drawings:

1. comparative example 1 is an oil-in-water emulsion prepared by adding the active ingredient and the oil humectant in the water-in-oil foundation fluid of the present invention at the same ratio;

2. comparative example 2 is that hyaluronic acid microspheres in the foundation fluid are replaced by the same type of hyaluronic acid microspheres on the market;

3. comparative example 3 is a commercial version of hydrolyzed pea protein substituted for the hydrolyzed pea protein in the liquid foundation of the invention;

4. comparative examples 4 to 6 are foundation liquids obtained by arbitrarily removing one of the functional components from the foundation liquid of the present invention in comparative example 1.

Efficacy verification

1. Testing an instrument:

(1) the Cutomer @ dual MPA 580, MPA system of CK, germany, is a multifunctional analysis system that can connect multiple probes simultaneously, each probe has different analysis windows. The probe used for testing of the invention comprises: corneometer CM825 (moisture test probe), cutomer MPA 580 (skin elasticity test probe)

(2) Image analyzer VISIA-CR of Canfield corporation, and data processing with ImageProPlus image processing software

2. The test method comprises the following steps:

the test is divided into 3 groups, 20 persons (the age is between 25 and 60 years) are selected from each group, the tested persons are screened (the facial skin has no symptoms of lesion, allergy, damage and the like), the tested persons are informed of relevant test risks, relevant informed consent is signed, each group uses the embodiment of the invention on the right face, the left face uses the comparative example, the foundation liquid is wiped on the face after the face is cleaned every morning, the face is continuously used for 4 weeks, and the skin conditions of the left face and the right face are tested by a skin elasticity tester (Cutomer MPA 580) and a facial skin imaging analysis system VISIA-CR.

3. And (3) testing conditions are as follows:

the subject sits still for 30 minutes at room temperature of 20-24 ℃ and relative humidity of 45-55% after cleaning the face before testing, and orders to relax facial muscles and slightly close eyes, and uses Cutomer @ dual MPA 580 to detect facial skin elasticity and water content, and the probe repeatedly measures for 3 times in the same tested area during measurement, and an average value is taken; using VISIA-CR to test left, middle and right triangular face photographing of the face, processing the image by professional IPP software provided by an instrument manufacturer, converting skin photographing characteristics into quantitative data, and then performing mean value calculation and T test analysis; the test is divided into 5 times, and the indexes of the skin of the test subject in 0 th, 1 st, 2 th, 3 th and 4 th weeks are respectively tested.

4. And (3) testing results:

(1) skin moisture test

The moisture content (MMV) of the skin affects the formation of a water and grease mixed film on the skin surface, and this protective film is very important to prevent aging of the skin. The greater the value of skin moisture content (MMV), the better the skin moisturizes and the more moist the skin. The test set the skin moisture content at week 0 as MMV0, week 4 as MMV4, the skin moisture content variation value as Δ MMV,. DELTA.mmv = MMV4-MMV0,. DELTA.mmv is a positive number and the higher the number, indicating that the more the moisture content of the skin increases after 4 weeks of product use, the better the moisturizing performance of the product, table 1 shows the average. DELTA.mmv values for each group of 20 people as follows:

group of	Mean value of Δ MMV
		Example 1	16.7375
Comparative example 1	13.3125
		Example 2	21.0000
Comparative example 2	19.4833
		Example 3	24.2667
Comparative example 3	16.5444
		Comparative example 4	9.0984
Comparative example 5	10.1143
		Comparative example 6	11.6427

TABLE 1

Experimental data show that:

the higher the value of the triangle MMV, the higher the moisture content of the skin, the stronger the moisturizing capability of the product, and as can be seen from the data in Table 1, the higher the content of the main effective components of the foundation fluid of the invention, the higher the increase of the moisture content of the skin, that is, the better the moisturizing effect. The delta MMV value of the composition in the embodiment 1 is higher than that of the composition in the comparative example 1, which shows that the composition has more excellent effect in water-in-oil products than common oil-in-water products, namely the moisturizing effect of the composition applied to foundation liquid products is very good; the Δ MMV value of example 2 is higher than that of comparative example 2, indicating that the moisturizing effect of the hyaluronic acid microspheres used in the present invention is superior to that of similar products on the market; the higher Δ MMV value of example 3 compared to comparative example 3 indicates that the hydrolysed pea proteins according to the invention have a much better moisturising effect than the commercially available hydrolysed pea proteins. As shown in a bar chart of figure 2, the beneficial moisturizing effect of the foundation liquid of the composition can be more visually seen, and the skin can be moisturized and plump.

(2) Skin elasticity test

The skin elasticity test principle is based on the suction and stretching principle, negative pressure is generated on the surface of the tested skin to suck the skin into a specific test probe, and the depth of the skin sucked into the test probe is measured by a non-contact optical test system. The test probe comprises a light emitter and a light receiver, the ratio of light (the ratio of emitted light to received light) is in direct proportion to the depth of the skin sucked, so that a relation curve of the stretched length of the skin and the time is obtained, then the elasticity performance of the skin is confirmed through MPA software, the elasticity value is a ratio, the maximum is 1, and the closer to 1, the better the elasticity of the skin is.

The skin elasticity values at 0 weeks, one week, two weeks, three weeks and four weeks were measured, respectively, and the skin elasticity change values of each person were calculated as Δ a, = Δ A4- Δ A0, and the average value of 20 persons was taken as the final test result, and the values are shown in table 2.

Group of	Average value of Delta A
		Example 1	0.1326
Comparative example 1	0.0921
		Example 2	0.1977
Comparative example 2	0.1400
		Example 3	0.2386
Comparative example 3	0.1542
		Comparative example 4	0.0425
Comparative example 5	0.1033
		Comparative example 6	0.0837

TABLE 2

Experimental data show that:

the higher the value of Delta A, the more the elasticity value is increased, i.e. the more the elasticity of the product on the skin is increased

The Δ a values of examples 1, 2 and 3 are rising, and show that the higher the content of the composition of the present invention, the more the elasticity of the skin is increased, and the more the skin is saturated with water and has elasticity.

The delta A value of example 1 is greater than that of comparative example 1, which shows that the effect of using the composition of the invention in foundation liquid is better than that of putting the composition in an oil-in-water product, so that when the composition of the invention is applied to foundation liquid, the foundation liquid can have more excellent effect than other types of skin care products, and the skin can be fuller and more elastic; the delta A value of the foundation liquid of the invention which is removed randomly is far smaller than that of the example 1, which shows that the elasticity value of the skin is increased little no matter which component is removed, namely the elasticity and the plumpness of the skin are not as same as the foundation liquid of the invention.

The delta A value of the example 2 is larger than that of the comparative example 2, which shows that the sodium hyaluronate microspheres used in the invention penetrate into the skin to achieve the effect of increasing the skin elasticity better than similar products on the market.

The Δ a value of example 3 is greater than that of comparative example 3, indicating that the hydrolyzed pea protein used in the composition of the invention provides a much higher improvement in skin elasticity than the similar hydrolyzed pea protein commercially available.

A more visual comparison is shown in FIG. 3, the effect of increasing the skin elasticity value

(3) Skin texture and fishtail texture testing

Using the VISIA-CR test, skin texture and crow's feet data are ratios of the area of the texture to a selected area percentage, with smaller ratios indicating less texture and wrinkles and smoother skin.

The skin texture and the fishtail line values at 0 week, one week, two weeks, three weeks and four weeks were measured, respectively, the variation value for each person was calculated, the skin texture was recorded as Δ TE, = Δ TE 4- Δ TE 0, the fishtail line was recorded as Δ CF, = Δ CF 4- Δ CF 0, and the average value of 20 persons was taken as the final test result, and the values are shown in table 3.

Group of	Delta TE average (%)	Δ CF mean (%)
			Example 1	-0.2900	-0.7075
Comparative example 1	-0.1839	-0.4937
			Example 2	-1.0575	-2.0811
Comparative example 2	-0.8878	-1.6278
			Example 3	-1.5014	-3.1550
Comparative example 3	-0.9487	-1.4200
			Comparative example 4	0.0371	0.0545
Comparative example 5	-0.1483	-0.3792
			Comparative example 6	-0.1034	-0.2651

TABLE 3

Experimental data show that:

the smaller the TE value and the CF value of the skin texture are, the better the anti-aging effect of the product is, therefore, the smaller the numerical value of Delta TE and Delta CF is, the better the anti-aging effect of the product is, as can be seen from the table 3, in the examples 1, 2 and 3 of the invention, along with the increase of the content of the effective components of the composition, the smaller the numerical value of Delta TE and Delta CF is, the increase of the content of the effective components is, the better the anti-aging effect of the product on the skin is, the smoother the skin is, and the composition of the invention particularly improves the fishtail texture is more obvious, the visual columnar comparison graph is shown in fig. 4, and the effect can be seen more clearly through pictures shot by VISIA-CR, and particularly shown in the attached drawings 5-7;

from the above values, it can be seen that the Δ TE, Δ CF values of example 1 are lower than those of comparative example 1, which indicates that the composition of the present invention is made into a water-in-oil foundation, which has better anti-wrinkle and anti-aging effects than an oil-in-water skin care product in example 1, but the hyaluronic acid microspheres used in the present invention have better stability and permeability in the water-in-oil system, and thus the effect is better.

Comparative example 4 in the present invention example 1, in which hyaluronic acid microspheres were removed, and the data were analyzed, some subjects showed increase and decrease in Δ TE and Δ CF, and both Δ TE and Δ CF were positive numbers in terms of average values, indicating that foundation fluid prepared without adding hyaluronic acid microspheres increased skin wrinkles more significantly, and did not achieve anti-aging effect. Both the Δ TE and Δ CF values of comparative examples 5 and 6 are much greater than those of inventive example 1, indicating that whichever component of the inventive composition is removed, the effect on the anti-aging effect of the final foundation fluid is greater and there is no very good anti-wrinkle skin-texture-smoothing effect.

The comparative example 2 has a larger value of Δ TE and Δ CF than example 2, which shows that the hyaluronic acid microspheres of the composition of the present invention are changed to similar hyaluronic acid microspheres on the market, and the texture and the crow's feet are not improved as well as the composition of the present invention, i.e. the hyaluronic acid microspheres used in the composition of the present invention have more excellent anti-wrinkle effect. Comparative example 3 the hydrolyzed pea protein of the composition of the invention was replaced by a commercially available hydrolyzed pea protein having a delta TE, delta CF value which is also greater than that of the composition of the invention, indicating that the hydrolyzed pea protein used in the composition of the invention has a much better anti-aging effect than the commercially available equivalent.

Although the embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that: various substitutions, alterations and modifications are possible without departing from the spirit and scope of this disclosure and appended claims, and accordingly, the scope of this disclosure is not limited to the embodiments disclosed. Although the embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that: various substitutions, changes and modifications are possible without departing from the spirit and scope of the invention and the appended claims, and therefore the scope of the invention is not limited to the embodiments disclosed.

Claims

1. A foundation liquid with moisturizing and anti-aging effects is characterized in that: the moisturizing and anti-aging liquid foundation comprises:

phase A:

1-5% of PEG-10 polydimethylsiloxane;

3-30% of cyclopentasiloxane;

0.1-1% of tocopherol acetate;

3-15% of titanium dioxide;

0.1 to 5 percent of pearl powder;

0.1-2% of iron oxide;

0.5 to 10 percent of hyaluronic acid microspheres;

30.01-1% of ceramide;

0.2 to 2 percent of bentonite;

phase B:

0.1-5% of hydrolyzed pea protein;

2-10% of glycerol;

0.02-1% of ethylhexyl glycerol;

0.1 to 1 percent of phenoxyethanol;

the balance of pure water is,

the hyaluronic acid microspheres comprise:

sodium hyaluronate is more than or equal to 0.1%;

50-100% of hydrogenated polyisobutene;

1-20% of trihydroxy stearin;

the glucomannan is not less than 0.01%,

the method comprises the following steps: 1% of sodium hyaluronate with a molecular weight of 5 ten thousand was added to 1, 4-butanediol diglycidyl ether: 0.25mol/L sodium hydroxide solution =1 in a solution with the volume of 10, uniformly stirring, heating to 50-60 ℃, reacting for 4-72h, and cooling to 25 ℃;

the method is characterized by comprising the following steps: after the reaction is finished, dropwise adding a hydrochloric acid solution to adjust the pH value to be neutral 7;

and step three, purification: adding 0.2mol/L phosphate buffer solution, and stirring and purifying for 2h at room temperature;

fourthly, freeze drying: sieving with a 80-mesh filter screen, pre-freezing the intercepted substance at-20 ℃ for 1h, at-40 ℃ and under the vacuum degree of 80-100 Pa, carrying out sublimation drying for 2h, and carrying out resolution drying for 2h at 45 ℃ and under the vacuum degree of 50-60 Pa to obtain a semi-finished product of hyaluronic acid microspheres;

preparing: mixing the filtered semi-finished product of hyaluronic acid microspheres with hydrogenated polyisobutene, trihydroxystearin and glucomannan in proportion and stirring uniformly.

2. The foundation liquid with moisturizing and anti-aging effects as claimed in claim 1, wherein: the preparation method of the hydrolyzed pea protein comprises the following steps:

preprocessing: preparing pea protein powder into a pea protein aqueous solution with the concentration of 2-4% by using purified water, adjusting the pH value to 6-8.5 by using 0.1mol/LNaOH solution, heating the solution to 85 ℃, and keeping the temperature for 15 minutes;

the method comprises the following steps of: adding compound protease into the pea protein solution, wherein the enzyme adding amount is 3500-6000u/g, and the enzymolysis treatment time is 3-12h;

the enzyme deactivation: rapidly heating the enzymolysis solution to 90 deg.C, maintaining for 20min, and cooling to room temperature;

fourth, centrifugal separation: centrifuging at 2000r/min for 15min to obtain upper filtrate;

filtering: filtering the obtained filtrate with 200 mesh filter screen, and ultrafiltering to obtain polypeptide solution with molecular weight of 1000 or less.

3. The foundation liquid with moisturizing and anti-aging effects as claimed in claim 2, wherein: the method is characterized in that: the compound protease is papain and bromelain.

4. The foundation liquid with moisturizing and anti-aging effects as claimed in claim 2, wherein: in the second step, 0.1mol/L NaOH solution is added in the enzymolysis process to maintain the pH constant.

5. The foundation liquid with moisturizing and anti-aging effects as claimed in claim 1, wherein: the iron oxide comprises one or more of iron oxide red, iron oxide yellow and iron oxide black.

6. The preparation method of the foundation liquid with the effects of moisturizing and resisting aging as claimed in claim 1, which is characterized by comprising the following steps: the method comprises the following steps:

weighing a phase A material, uniformly mixing, and homogenizing to completely disperse all components;

weighing the material of the phase B, and uniformly stirring;

and thirdly, slowly pouring the phase B into the phase A under stirring, and homogenizing and emulsifying for 2-8 minutes to completely disperse the materials to obtain the foundation solution.

7. The preparation method of the foundation liquid with the effects of moisturizing and resisting aging according to claim 6, which is characterized by comprising the following steps: the homogeneous emulsification condition is vacuum degree of-0.05 mpa.