CN111514045A - Alcohol-free no-clean disinfection hand sanitizer with skin care effect and preparation method thereof - Google Patents
Alcohol-free no-clean disinfection hand sanitizer with skin care effect and preparation method thereof Download PDFInfo
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- CN111514045A CN111514045A CN202010350363.3A CN202010350363A CN111514045A CN 111514045 A CN111514045 A CN 111514045A CN 202010350363 A CN202010350363 A CN 202010350363A CN 111514045 A CN111514045 A CN 111514045A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention provides an ethanol-free no-clean disinfection hand sanitizer with skin care effect, which comprises the following components in percentage by mass: 1.0 to 10.0 percent of humectant, 0.05 to 2.0 percent of disinfectant, 0.05 to 2.0 percent of skin care agent, 0.01 to 2.0 percent of wetting agent, 0.05 to 2.0 percent of preservative, 0.05 to 2.0 percent of metal ion chelating agent, 0.1 to 0.5 percent of essence and 0.05 to 2.0 percent of pH regulator; the balance of deionized water; wherein the skin care agent is one or a mixture of wheat germ extract and rice germ extract; the disinfectant is benzalkonium chloride or benzalkonium bromide. The invention also provides a preparation method of the ethanol-free wash-free disinfection hand sanitizer with the skin care effect. The hand sanitizer provided by the invention does not contain ethanol, and is mild and non-irritant to skin.
Description
Technical Field
The invention relates to the technical field of hand sanitizer, in particular to an ethanol-free washing-free disinfection hand sanitizer with a skin care effect and a preparation method thereof.
Background
At the end of 12 months in 2019, the epidemic situation of the novel coronavirus pneumonia explodes, and the infection prevention is very critical under the condition that no specific medicine or vaccine exists, and the general prevention guideline for the pneumonia infected by the novel coronavirus indicates that: (1) the individual should maintain hand hygiene: applying the disinfection hand sanitizer to wash hands after contacting with public articles; (2) the goods and the environment are disinfected conventionally: for disinfecting bathroom and toilet surfaces, public supplies are disinfected at least 1-2 times per day, and chlorine-containing disinfectants and peracetic acid disinfectants are recommended.
Most of the current commercially available hand sanitizer mainly contains an ethanol disinfectant, but the hand sanitizer not only generates pungent alcohol smell, but also can damage hand skin after long-term use due to the addition of a large amount of ethanol, and most importantly, the hand sanitizer is flammable and explosive, has combustion risk when used in public places, and is not suitable for places with concentrated crowds such as bus stations, subway stations and the like. It is therefore desirable to provide a hand sanitizer that does not contain ethanol.
Disclosure of Invention
In view of the above, the invention provides the ethanol-free washing-free disinfection hand sanitizer with the skin care effect, and the hand sanitizer provided by the invention does not contain ethanol, is mild and has no stimulation to skin; the invention also provides a preparation method of the ethanol-free wash-free disinfection hand sanitizer.
The invention provides an ethanol-free no-clean disinfection hand sanitizer with skin care effect, which comprises the following components in percentage by mass: 1.0 to 10.0 percent of humectant, 0.05 to 2.0 percent of disinfectant, 0.05 to 2.0 percent of skin care agent, 0.01 to 2.0 percent of wetting agent, 0.05 to 2.0 percent of preservative, 0.05 to 2.0 percent of metal ion chelating agent, 0.1 to 0.5 percent of essence and 0.05 to 2.0 percent of pH regulator; the balance being deionized water.
Further, the humectant is glycerin; the disinfectant is benzalkonium chloride or benzalkonium bromide, preferably benzalkonium chloride; the skin care agent is one or a mixture of wheat germ extract and rice germ extract, preferably wheat germ extract; the wetting agent is tween 20; the preservative is phenoxyethanol; the metal ion chelating agent is EDTA-2 Na; the pH regulator is citric acid or sodium hydroxide; the essence is any one of lavender essence, lemon essence and rose essence.
The invention also provides a preparation method of the alcohol-free no-clean disinfection hand sanitizer with the skin care effect, which comprises the following steps:
s1, sequentially adding the metal ion chelating agent, the disinfectant, the humectant, the skin care agent and the humectant into deionized water, and stirring at a rotating speed of 150-250 r/min for 5-10 min to obtain a first mixed solution;
s2, adding a preservative into 1/10-1/6 volume of the first mixed solution, and fully and uniformly stirring at a rotating speed of 150-250 r/min to obtain a second mixed solution;
s3, adding the second mixed solution into the rest of the first mixed solution, stirring at a rotating speed of 150-250 r/min for 5-10 min, and then adding a pH regulator to adjust the pH value of the solution to 6.0-7.0 to obtain a third mixed solution;
and S4, adding essence into the third mixed solution, stirring at the rotating speed of 150-250 r/min for 2-3 min, and uniformly mixing to obtain the alcohol-free no-clean disinfection hand sanitizer.
Compared with the prior art, the invention has the following beneficial effects:
1. the formula of the hand sanitizer provided by the invention takes benzalkonium chloride as a main component, and the benzalkonium chloride has quite strong spectrum bacteriostasis and sterilization effects and has obvious killing or inhibiting effects on influenza viruses (A, B), avian influenza viruses and the like; the benzalkonium chloride has stable property, is not flammable and volatile, is suitable for crowded places such as subways, bus stations, railway stations and the like, and cannot cause combustion risk; the benzalkonium chloride can be used for surgical trauma and skin mucosa disinfection, has aromatic smell and no irritation, can be widely used for various people, and has universality for pregnant women and infants;
2. the hand sanitizer formula provided by the invention contains the moisturizing glycerin, so that the drying symptom generated by using a disinfectant can be improved, and the hand skin can be protected;
3. the formula of the hand sanitizer provided by the invention contains the wheat germ extract and the rice germ extract, and the wheat germ extract and the rice germ extract are rich in natural vitamin E, are high-quality antioxidants and emollients, are easy to be absorbed by skin, and can promote the normal development of muscles and the metabolism of the skin, so that the elasticity of the skin is kept, the safety is high, and the skin care effect is excellent;
4. the preparation method of the hand sanitizer provided by the invention is simple and easy to operate, and the raw materials can be ensured to be fully and uniformly mixed by strictly controlling the stirring speed and the stirring time of each step.
Drawings
FIG. 1 is a schematic flow chart of a method for preparing an alcohol-free hand sanitizer with skin care effect according to the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be further described with reference to the accompanying drawings.
The embodiment of the invention provides an ethanol-free no-clean disinfection hand sanitizer with a skin care effect, which comprises the following components in percentage by mass: 1.0 to 10.0 percent of humectant, 0.05 to 2.0 percent of disinfectant, 0.05 to 2.0 percent of skin care agent, 0.01 to 2.0 percent of wetting agent, 0.05 to 2.0 percent of preservative, 0.05 to 2.0 percent of metal ion chelating agent, 0.1 to 0.5 percent of essence and 0.05 to 2.0 percent of pH regulator; the balance being deionized water.
Wherein the humectant is glycerol; the disinfectant is benzalkonium chloride or benzalkonium bromide, preferably benzalkonium chloride; the skin caring agent is one or mixture of wheat germ extract and rice germ extract, preferably wheat germ extract; the wetting agent is tween 20; the preservative is phenoxyethanol; the metal ion chelating agent is EDTA-2 Na; the pH regulator is citric acid or sodium hydroxide; the essence is any one of lavender essence, lemon essence, rose essence, etc.
Referring to fig. 1, the embodiment of the present invention further provides a preparation method of the above alcohol-free no-wash disinfectant hand sanitizer with skin care effect, which comprises the following steps:
step S1, sequentially adding 0.05-2.0% of metal ion chelating agent, 0.05-2.0% of disinfectant, 1.0-10.0% of humectant, 0.05-2.0% of skin care agent and 0.01-2.0% of wetting agent into deionized water by mass percent, and stirring at the rotating speed of 150-250 r/min for 5-10 min to obtain a first mixed solution;
step S2, adding 0.05-2.0% (mass percentage) of preservative into 1/10-1/6 volume of the first mixed solution, and fully and uniformly stirring at a rotating speed of 150-250 r/min to obtain a second mixed solution;
step S3, adding the second mixed solution into the rest of the first mixed solution, stirring for 5-10 min at a rotating speed of 150-250 r/min, and then adding 0.05-2.0% (mass percent) of pH regulator to adjust the pH value of the solution to 6.0-7.0 to obtain a third mixed solution;
and step S4, adding 0.1-0.5% (mass percentage) of essence into the third mixed solution, stirring at the rotating speed of 150-250 r/min for 2-3 min, and uniformly mixing to obtain the alcohol-free no-clean disinfection hand sanitizer.
The following will explain the alcohol-free hand sanitizer with skin care effect and the preparation method thereof in detail by combining the examples.
Example 1:
weighing 30g of EDTA-2Na, 6g of benzalkonium chloride, 600g of glycerol, 6g of wheat germ extract and 6g of Tween 20, sequentially adding into 9kg of deionized water, and stirring at the rotating speed of 200r/min for 6min to obtain a first mixed solution; taking about 1kg of the first mixed solution, adding 5g of phenoxyethanol into the first mixed solution, and fully and uniformly stirring at the rotating speed of 160r/min to obtain a second mixed solution; weighing 5g of sodium hydroxide, adding the sodium hydroxide into 332g of deionized water, uniformly stirring to prepare a sodium hydroxide solution, adding the second mixed solution into the rest of the first mixed solution, stirring at the rotating speed of 200r/min for 8min, then adding the sodium hydroxide solution to adjust the pH value of the mixed solution to 6.0, and obtaining a third mixed solution; and adding 10g of lemon essence into the third mixed solution, stirring at the rotating speed of 200r/min for 2min, and uniformly mixing to obtain the alcohol-free no-clean disinfection hand sanitizer.
Example 2:
weighing 50g of EDTA-2Na, 12g of benzalkonium chloride, 400g of glycerol, 10g of wheat germ extract and 8g of Tween 20, sequentially adding into 9kg of deionized water, and stirring at the rotating speed of 200r/min for 6min to obtain a first mixed solution; taking about 1kg of the first mixed solution, adding 10g of phenoxyethanol into the first mixed solution, and fully and uniformly stirring at the rotating speed of 160r/min to obtain a second mixed solution; weighing 10g of sodium hydroxide, adding the sodium hydroxide into 485g of deionized water, uniformly stirring to prepare a sodium hydroxide solution, adding the second mixed solution into the rest of the first mixed solution, stirring at the rotating speed of 200r/min for 8min, adding the sodium hydroxide solution, and adjusting the pH value of the mixed solution to 6.5 to obtain a third mixed solution; and adding 15g of lemon essence into the third mixed solution, stirring at the rotating speed of 200r/min for 2min, and uniformly mixing to obtain the alcohol-free no-clean disinfection hand sanitizer.
Example 3:
weighing 100g of EDTA-2Na, 18g of benzalkonium chloride, 300g of glycerol, 16g of wheat germ extract and 10g of Tween 20, sequentially adding into 9kg of deionized water, and stirring at the rotating speed of 200r/min for 6min to obtain a first mixed solution; taking about 1kg of the first mixed solution, adding 20g of phenoxyethanol into the first mixed solution, and fully and uniformly stirring at the rotating speed of 160r/min to obtain a second mixed solution; weighing 30g of sodium hydroxide, adding 476g of deionized water, uniformly stirring to prepare a sodium hydroxide solution, adding the second mixed solution into the rest of the first mixed solution, stirring at the rotating speed of 200r/min for 8min, then adding the sodium hydroxide solution to adjust the pH value of the mixed solution to 7.0, and obtaining a third mixed solution; and adding 30g of lemon essence into the third mixed solution, stirring at the rotating speed of 200r/min for 2min, and uniformly mixing to obtain the alcohol-free no-clean disinfection hand sanitizer.
The sterilization effect test (2002 edition 'Disinfection technical Specification' of Ministry of health):
the alcohol-free no-clean disinfection hand sanitizer obtained in the example 3 is detected according to the requirements of 2002 edition 'disinfection technical Specification' of Ministry of health, and is used for respectively carrying out sterilization tests on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, candida albicans, natural bacteria on hands and natural bacteria on skin surfaces. The test results are shown in table 1:
table 1: test results for alcohol-free, leave-on sanitizing cleanser made in example 3
According to the requirement test of 2002 edition of disinfection technical Specification of Ministry of health, the no-clean disinfection hand sanitizer prepared in the example 3 acts on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, candida albicans, natural bacteria on hands and natural bacteria on the surface of skin for 1min, and the average killing logarithm value conforms to the specification of 2002 edition of disinfection technical Specification of Ministry of health.
Comparative example 1:
comparative example 1 differs from example 3 only in that: comparative example 1 no wheat germ extract was added when preparing the hand sanitizer; the remaining starting materials and preparation were essentially the same as in example 3.
Comparative example 2:
comparative example 2 differs from example 3 only in that: comparative example 2 when preparing a hand sanitizer 18g ethanol was added, no benzalkonium chloride was added; the remaining starting materials and preparation were essentially the same as in example 3.
The no-clean hand sanitizer prepared in examples 1-3 and comparative examples 1-2 are respectively filled into containers provided with foam pump heads, when in use, the liquid is directly pumped out through the foam pump heads, so that the liquid becomes foam after passing through the foam pump heads, and the foam is applied to the skin of hands. 100 volunteers were randomly selected and divided into A, B, C, D, E groups of 20 groups, wherein the group A volunteers were coated with the hand sanitizer prepared in example 1, the group B volunteers were coated with the hand sanitizer prepared in example 2, the group C volunteers were coated with the hand sanitizer prepared in example 3, the group D volunteers were coated with the hand sanitizer prepared in comparative example 1, and the group E volunteers were coated with the hand sanitizer prepared in comparative example 2, and the proportion of dry skin, neutral skin and mixed skin in each group was about the same. The skin moisture tester is used for testing the moisture change of hands of volunteers before and after the hands are coated with the disinfection hand sanitizer, and the test results are shown in table 2:
table 2: test results for sanitizing hand sanitizer of examples 1-3 and comparative examples 1-2
| Group of | Before use (average value) | After use (average value) |
| Group A | 18％ | 33％ |
| Group B | 21％ | 31％ |
| Group C | 18％ | 31％ |
| Group D | 18％ | 22％ |
| Group E | 20％ | 23％ |
It can be seen from the experimental results that the water content of the skin of the no-clean hand sanitizer prepared in the examples 1 to 3 is higher than that of the no-clean hand sanitizer prepared in the comparative examples 1 to 2, and the skin of the hands washed by the no-clean hand sanitizer prepared in the examples 1 to 3 is smooth and not tight, and the effect is better than that of the hand sanitizer containing ethanol.
The features of the embodiments and embodiments described herein above may be combined with each other without conflict.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (7)
1. An ethanol-free no-clean disinfection hand sanitizer with skin care effect is characterized by comprising the following components in percentage by mass: 1.0 to 10.0 percent of humectant, 0.05 to 2.0 percent of disinfectant, 0.05 to 2.0 percent of skin care agent, 0.01 to 2.0 percent of wetting agent, 0.05 to 2.0 percent of preservative, 0.05 to 2.0 percent of metal ion chelating agent, 0.1 to 0.5 percent of essence and 0.05 to 2.0 percent of pH regulator; the balance of deionized water; wherein the skin care agent is one or a mixture of wheat germ extract and rice germ extract; the disinfectant is benzalkonium chloride or benzalkonium bromide.
2. The ethanol-free no-clean disinfection hand sanitizer with skin care effect of claim 1, wherein the moisturizing agent is glycerin; the wetting agent is tween 20; the preservative is phenoxyethanol; the metal ion chelating agent is EDTA-2 Na; the pH regulator is citric acid or sodium hydroxide; the essence is any one of lavender essence, lemon essence and rose essence.
3. The preparation method of the ethanol-free no-clean disinfection hand sanitizer with skin care effect of claim 2, which is characterized by comprising the following steps:
s1, sequentially adding the metal ion chelating agent, the disinfectant, the humectant, the skin care agent and the humectant into deionized water, and stirring to obtain a first mixed solution;
s2, adding a preservative into 1/10-1/6 volume of the first mixed solution, and fully and uniformly stirring to obtain a second mixed solution;
s3, adding the second mixed solution into the rest of the first mixed solution, stirring, and then adding a pH regulator to adjust the pH value of the solution to 6.0-7.0 to obtain a third mixed solution;
and S4, adding essence into the third mixed solution, and uniformly stirring to obtain the alcohol-free no-clean disinfection hand sanitizer.
4. The preparation method of the ethanol-free no-clean disinfection hand sanitizer with skin care effect according to claim 3, wherein the stirring process in the step S1 is as follows: stirring the mixture for 5 to 10min at a rotating speed of 150 to 250 r/min.
5. The preparation method of the ethanol-free no-clean disinfection hand sanitizer with skin care effect as claimed in claim 3, wherein the stirring speed in the step S2 is 150-250 r/min.
6. The preparation method of the ethanol-free no-clean disinfection hand sanitizer with skin care effect according to claim 3, wherein the stirring process in the step S3 is as follows: stirring the mixture for 5 to 10min at a rotating speed of 150 to 250 r/min.
7. The preparation method of the ethanol-free no-clean disinfection hand sanitizer with skin care effect according to claim 3, wherein the stirring process in the step S4 is as follows: stirring the mixture for 2 to 3min at a rotating speed of 150 to 250 r/min.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111700824A (en) * | 2020-08-13 | 2020-09-25 | 郑州中科新兴产业技术研究院 | Alcohol-free sweet wormwood wax oil washing-free antibacterial hand sanitizer and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2699404A1 (en) * | 1992-12-18 | 1994-06-24 | Oreal | Biphase cosmetic or dermatological composition for removing makeup, cleansing or skin care containing benzalkonium chloride. |
| CN110742841A (en) * | 2019-10-28 | 2020-02-04 | 广州私尚贸易有限公司 | Washing-free bacteriostatic lotion and preparation method thereof |
-
2020
- 2020-04-28 CN CN202010350363.3A patent/CN111514045A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2699404A1 (en) * | 1992-12-18 | 1994-06-24 | Oreal | Biphase cosmetic or dermatological composition for removing makeup, cleansing or skin care containing benzalkonium chloride. |
| CN110742841A (en) * | 2019-10-28 | 2020-02-04 | 广州私尚贸易有限公司 | Washing-free bacteriostatic lotion and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 杨嘉萌: "植物提取物在化妆品中的应用及展望", 《日用化学工业》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111700824A (en) * | 2020-08-13 | 2020-09-25 | 郑州中科新兴产业技术研究院 | Alcohol-free sweet wormwood wax oil washing-free antibacterial hand sanitizer and preparation method thereof |
| CN111700824B (en) * | 2020-08-13 | 2024-01-23 | 中科行发医疗科技有限公司 | Alcohol-free sweet wormwood wax oil washing-free antibacterial hand sanitizer and preparation method thereof |
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