CN111481474A - Mouth cleaning liquid and preparation method thereof - Google Patents
Mouth cleaning liquid and preparation method thereof Download PDFInfo
- Publication number
- CN111481474A CN111481474A CN202010450123.0A CN202010450123A CN111481474A CN 111481474 A CN111481474 A CN 111481474A CN 202010450123 A CN202010450123 A CN 202010450123A CN 111481474 A CN111481474 A CN 111481474A
- Authority
- CN
- China
- Prior art keywords
- parts
- essential oil
- cleaning liquid
- mouth
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention relates to a mouth cleaning liquid and a preparation method thereof, belonging to the technical field of oral care. The mouth cleaning liquid consists of the following raw materials: the ginger juice beverage is prepared from Zingiber corallinum Hance essential oil, spearmint essential oil, mint essential oil, edible ethanol, a foaming agent, an edible preservative, a sweetening agent, a plant spice, sodium percarbonate and water. The preparation method of the mouth cleaning liquid comprises the following steps: s1, weighing raw materials; s2, adding a sweetening agent and sodium percarbonate into water, stirring and dissolving to obtain a solution A; s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring to obtain a solution B; s4, slowly adding the solution B into the solution A to obtain a solution C; s5, adding the foaming agent, the edible preservative and the plant spice into the solution C to obtain the mouth cleaning liquid. The mouth cleaning liquid has high adhesiveness of oil components, is easier to fill oral teeth, gums and mucous membranes than water, can improve the sterilization effect, and has a lasting effect.
Description
Technical Field
The invention belongs to the technical field of oral care, and particularly relates to a mouth cleaning liquid and a preparation method thereof.
Background
The mouth-cleaning liquid is one of the ways of cleaning the oral health. Due to the liquid property of the oral cleaning liquid, the oral cleaning liquid can penetrate into all parts of the oral cavity, so that bacteria and bacterial plaque causing halitosis are reduced, and the gum health is improved.
At present, the traditional oral cleaning liquid comprises antibiotic oral cleaning liquid or traditional Chinese medicine extract oral cleaning liquid. An antibiotic oral liquid, such as chlorhexidine, is a biguanide disinfectant with the widest application and the strongest anti-bacterial spot capability, and can effectively inhibit gram-positive bacteria and keep the oral hygiene. However, antibiotic mouth rinses tend to cause staining of the tooth surface and tongue mucous membrane and bitter taste, and a few of them may also cause dysgeusia. The traditional Chinese medicine extract mouth-cleaning liquid has natural raw materials and can play a certain role in diminishing inflammation and sterilizing, but the traditional Chinese medicine extract mouth-cleaning liquid is generally formed by mixing traditional Chinese medicine extracting solution and water, and when the mouth-cleaning liquid is used, the oral teeth, the gum and the mucous membrane are not easily filled, so that the cleaning effect is not thorough. Therefore, there is a need in the market for a mouth-cleansing liquid product that can achieve both the bactericidal effect and the cleansing efficiency.
Disclosure of Invention
The invention aims to provide a mouth cleaning liquid, which can solve the technical problems of great side effect and poor cleaning efficiency of the existing mouth cleaning liquid.
The technical scheme for solving the technical problems is as follows:
a mouth cleaning liquid is composed of the following raw materials in parts by mass: 2-8 parts of coral ginger essential oil, 1-5 parts of spearmint essential oil, 0.5-3.5 parts of mint essential oil, 2-5 parts of edible ethanol, 0.1-0.4 part of foaming agent, 0.01-0.04 part of edible preservative, 0.1-0.5 part of sweetening agent, 0.01-0.04 part of plant spice, 0.4-1.8 parts of sodium carbonate peroxide and 76-96 parts of water.
The action and mechanism of the raw materials of the invention are as follows:
the Zingiber corallinum Hance is rhizome of Zingiber of Zingiberaceae, which has bitter taste and cold property, and can be used for invigorating stomach and resolving food stagnation, and can be used for treating food stagnation, abdominal pain, nausea, emesis, hepatosplenomegaly and hot wind damp pain, etc. the Zingiber corallinum Hance contains volatile components terpinen-4-ol, β -bisabolene, coumarane, methyl 3-methoxy hydroxy cinnamate, 3, 4-dimethyl benzaldehyde, limonene and anthraquinonoid glycoside, and Zingiber corallinum Hance essential oil has broad-spectrum antibacterial and unique antibacterial functions, and has important effect in preventing and treating animal diseases.
Mentha spicata, Mentha, Labiatae, pungent and sweet with mild temperature, and is used as the whole herb. Collected all the year round, and used fresh or dried in the shade. It is used to treat wind and cold, cough, swelling and toxic materials. Can be used for treating common cold, cough, gastralgia, abdominal distention, and nervous headache; it is used externally to treat swelling and pain due to traumatic injury, conjunctivitis, and furuncle of children. The spearmint essential oil is light yellow or light green, and comprises main chemical components of pinene or pinene, carvone, cineole, linalool, limonene, myrcene, caryophyllene and menthone. The spearmint essential oil can relieve the congestion state of the oral cavity, and the fragrance of the spearmint essential oil can relieve nervous tension, and has the effects of dispelling wind, relieving exterior syndrome, diminishing inflammation, relieving pain, resisting bacteria, killing insects and the like.
Herba Menthae is Labiatae, i.e. other dried whole herbs of the same genus. The whole plant is green and fragrant. The leaves are in pairs, the flowers are small and light purple, the lips are shaped, and dark purple brown small-grain fruits are formed after the flowers are bloomed. Herba Menthae is pungent and cool, and has effects of inducing sweat and clearing heat, and can be used for treating influenza, headache, conjunctival congestion, fever, and swelling and pain of throat and gum. The peppermint essential oil has peppermint flavor, and can clear and moisten throat, eliminate halitosis, relieve physical and mental stress, and refresh mind.
The mouth cleaning liquid has the beneficial effects that:
(1) the mouth cleaning liquid contains a proper amount of oil components (such as Zingiber corallinum Hance essential oil, spearmint essential oil and mint essential oil), the adhesiveness of the oil components is higher, oral teeth, gums and mucous membranes can be filled more easily than water, and bacteria in the oral cavity have lipophilicity, so that the sterilization effect can be improved, and the effect is lasting;
(2) the essential oil of Zingiber corallinum Hance, the essential oil of spearmint and the essential oil of mint have remarkable sterilizing effect, and have the functions of diminishing inflammation, reducing swelling and easing pain, and oily components can help the oral cavity to keep healthy continuously;
(3) the invention not only can clean the oral cavity, kill bacteria in the oral cavity and refresh breath, but also can remove dental plaque, whiten teeth, remove and prevent dental calculus and prevent dental caries.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the feed additive comprises the following raw materials in parts by mass: 3-4 parts of coral ginger essential oil, 2-3 parts of spearmint essential oil, 0.8-2.2 parts of mint essential oil, 2.5-4 parts of edible ethanol, 0.2-0.3 part of foaming agent, 0.02-0.03 part of edible preservative, 0.2-0.4 part of sweetener, 0.02-0.03 part of plant spice, 0.5-1.3 parts of sodium percarbonate and 80-85 parts of water.
Further, the feed additive comprises the following raw materials in parts by mass: 3 parts of coral ginger essential oil, 2.5 parts of spearmint essential oil, 1.5 parts of mint essential oil, 3 parts of edible ethanol, 0.25 part of foaming agent, 0.02 part of edible preservative, 0.3 part of sweetener, 0.02 part of plant spice, 0.8 part of sodium percarbonate and 84 parts of water.
Further, the foaming agent is any one or a mixture of more than two of carbon dioxide, cocamidopropyl betaine or sodium dodecyl sulfate.
The beneficial effect of adopting the further scheme is that: the foaming agent is properly added, so that a large amount of foam can be generated when the mouth cleaning liquid is used, and the cleaning effect on the oral cavity is improved; the compound sodium percarbonate has better whitening effect on teeth by matching with sodium peroxycarbonate.
Further, the edible preservative is potassium sorbate or sodium benzoate.
The beneficial effect of adopting the further scheme is that: the mouth cleaning liquid of the invention has mild taste, does not contain fluoride and chloride, has no toxic or side effect, and lays a foundation for long-term use of the mouth cleaning liquid.
Further, the sweetener is xylitol or stevioside.
The beneficial effect of adopting the further scheme is that: the addition of proper sweetener is helpful to improve the taste of the mouth cleaning liquid and improve the use pleasure of customers.
Further, the plant spice is any one or a mixture of more than two of camellia powder, sweet osmanthus powder and jasmine powder.
The beneficial effect of adopting the further scheme is that: the plant spice can improve the fragrance of the mouth cleaning liquid, brings more comfortable use experience to people, and simultaneously helps to keep the oral cavity fresh.
Further, the water is deionized water.
The beneficial effect of adopting the further scheme is that: the deionized water can reduce the influence of impurities on effective components, and improve the production effect and use experience of the mouth cleaning liquid.
In addition, another object of the present invention is to provide a method for preparing the above oral cavity cleansing liquid, which can solve the technical problem that the existing oral cavity cleansing liquid is inconvenient to prepare.
The technical scheme for solving the technical problems is as follows:
a preparation method of a mouth cleaning liquid comprises the following steps:
s1, weighing the following raw materials in parts by mass: 2-8 parts of coral ginger essential oil, 1-5 parts of spearmint essential oil, 0.5-3.5 parts of mint essential oil, 2-5 parts of edible ethanol, 0.1-0.4 part of foaming agent, 0.01-0.04 part of edible preservative, 0.1-0.5 part of sweetening agent, 0.01-0.04 part of plant spice, 0.4-1.8 parts of sodium carbonate peroxide and 76-96 parts of water;
s2, adding a sweetening agent and sodium percarbonate into water, stirring and dissolving to obtain a solution A;
s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring to obtain a solution B;
s4, slowly adding the solution B obtained in the step S3 into the solution A obtained in the step S2 under the stirring state, and uniformly mixing to obtain a solution C;
s5, adding the foaming agent, the edible preservative and the plant spice into the solution C obtained in the step S4, and then stirring, standing, filtering and carrying out sterile treatment to obtain the mouth cleaning liquid.
The preparation method of the mouth cleaning liquid has the beneficial effects that:
the preparation method has simple process and few material types, ensures that all components are fully dissolved, and has higher market popularization value.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, in step S1, the foaming agent is any one or a mixture of two or more of carbon dioxide, cocamidopropyl betaine, and sodium lauryl sulfate; the edible preservative is potassium sorbate or sodium benzoate; the sweetener is xylitol or stevioside; the sweetener is xylitol or stevioside; the plant spice is any one or a mixture of more than two of camellia powder, sweet osmanthus powder and jasmine powder; the water is deionized water.
Further, in step S3, the heating temperature is 40 ℃ to 50 ℃.
The beneficial effect of adopting the further scheme is that: the dissolving degree between the essential oils can be improved by proper heating, and the integral effect of the mouth cleaning liquid is improved.
Further, in step S5, the standing time is 24-48 h.
The beneficial effect of adopting the further scheme is that: the proper standing is helpful for effective micro molecules in the oral cleaning liquid to diffuse, thereby achieving the effect of uniform distribution of the effective micro molecules.
Detailed Description
The technical solution of the present invention will be described in more detail with reference to the following embodiments, wherein the raw materials such as edible ethanol, foaming agent, edible preservative, sweetener, plant flavor, sodium percarbonate, water, essential oil of Zingiber corallinum Hance, essential oil of spearmint, and essential oil of peppermint are commercially available, for example, edible ethanol from Xinrunder chemical Co., Ltd, Hubei; zingiber corallinum Hance oil of Wuhan Runze Wei science and technology Limited.
Embodiment mode 1
The embodiment provides a mouth cleaning liquid which comprises the following raw materials in parts by mass: 2kg of Zingiber corallinum Hance essential oil, 5kg of spearmint essential oil, 0.5kg of mint essential oil, 2kg of edible ethanol, 0.1kg of cocamidopropyl betaine, 0.04kg of potassium sorbate, 0.1kg of xylitol, 0.04kg of camellia powder, 1.8kg of sodium percarbonate and 96kg of deionized water.
The preparation method of the mouth cleaning liquid comprises the following steps:
s1, weighing the following raw materials by mass: 2kg of Zingiber corallinum Hance essential oil, 5kg of spearmint essential oil, 0.5kg of mint essential oil, 2kg of edible ethanol, 0.1kg of cocamidopropyl betaine, 0.04kg of potassium sorbate, 0.1kg of xylitol, 0.04kg of camellia powder, 1.8kg of sodium percarbonate and 96kg of deionized water;
s2, adding a sweetening agent and sodium percarbonate into deionized water, stirring and dissolving to obtain a solution A;
s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring at 40 ℃ to obtain a solution B;
s4, slowly adding the solution B obtained in the step S3 into the solution A obtained in the step S2 under the stirring state, and uniformly mixing to obtain a solution C;
s5, adding the foaming agent, the edible preservative and the plant spice into the solution C obtained in the step S4, and then stirring, standing for 24 hours, filtering and carrying out sterile treatment to obtain the mouth cleaning liquid.
Embodiment mode 2
The embodiment provides a mouth cleaning liquid which comprises the following raw materials in parts by mass: 6kg of coral ginger essential oil, 1kg of spearmint essential oil, 3.5kg of mint essential oil, 5kg of edible ethanol, 0.4kg of sodium dodecyl sulfate, 0.01kg of sodium benzoate, 0.5kg of stevioside, 0.01kg of sweet osmanthus powder, 0.4kg of sodium percarbonate and 76kg of deionized water.
The preparation method of the mouth cleaning liquid comprises the following steps:
s1, weighing the following raw materials by mass: 6kg of coral ginger essential oil, 1kg of spearmint essential oil, 3.5kg of mint essential oil, 5kg of edible ethanol, 0.4kg of sodium dodecyl sulfate, 0.01kg of sodium benzoate, 0.5kg of stevioside, 0.01kg of sweet osmanthus powder, 0.4kg of sodium percarbonate and 76kg of deionized water;
s2, adding a sweetening agent and sodium percarbonate into deionized water, stirring and dissolving to obtain a solution A;
s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring at 50 ℃ to obtain a solution B;
s4, slowly adding the solution B obtained in the step S3 into the solution A obtained in the step S2 under the stirring state, and uniformly mixing to obtain a solution C;
s5, adding the foaming agent, the edible preservative and the plant spice into the solution C obtained in the step S4, and then stirring, standing for 48 hours, filtering and carrying out sterile treatment to obtain the mouth cleaning liquid.
Embodiment 3
The embodiment provides a mouth cleaning liquid which comprises the following raw materials in parts by mass: 3kg of Zingiber corallinum Hance essential oil, 2.5kg of spearmint essential oil, 1.5kg of mint essential oil, 3kg of edible ethanol, 0.25kg of carbon dioxide, 0.02kg of potassium sorbate, 0.3kg of xylitol, 0.02kg of jasmine pollen powder, 0.8kg of sodium percarbonate and 84kg of deionized water.
The preparation method of the mouth cleaning liquid comprises the following steps:
s1, weighing the following raw materials by mass: 3kg of Zingiber corallinum Hance essential oil, 2.5kg of spearmint essential oil, 1.5kg of mint essential oil, 3kg of edible ethanol, 0.25kg of carbon dioxide, 0.02kg of potassium sorbate, 0.3kg of xylitol, 0.02kg of jasmine pollen powder, 0.8kg of sodium percarbonate and 84kg of deionized water;
s2, adding a sweetening agent and sodium percarbonate into deionized water, stirring and dissolving to obtain a solution A;
s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring at the temperature of 45 ℃ to obtain a solution B;
s4, slowly adding the solution B obtained in the step S3 into the solution A obtained in the step S2 under the stirring state, and uniformly mixing to obtain a solution C;
s5, adding the foaming agent, the edible preservative and the plant spice into the solution C obtained in the step S4, stirring, standing for 36 hours, filtering and performing aseptic treatment to obtain the mouth cleaning liquid.
Embodiment 4
The difference between this embodiment and embodiment 3 is that the mouth wash is composed of the following raw materials: 3kg of Zingiber corallinum Hance essential oil, 2kg of spearmint essential oil, 0.8kg of mint essential oil, 4kg of edible ethanol, 0.3kg of carbon dioxide, 0.02kg of potassium sorbate, 0.2kg of xylitol, 0.03kg of jasmine pollen, 0.5kg of sodium percarbonate and 85kg of water.
Embodiment 5
The difference between this embodiment and embodiment 3 is that the mouth wash is composed of the following raw materials: 4kg of Zingiber corallinum Hance essential oil, 3kg of spearmint essential oil, 2.2kg of mint essential oil, 2.5kg of edible ethanol, 0.2kg of carbon dioxide, 0.03kg of potassium sorbate, 0.4kg of xylitol, 0.02kg of camellia powder, 1.3kg of sodium percarbonate and 80kg of water.
Comparative example 1
This embodiment is different from embodiment 3 in that the mouth-cleansing liquid contains a ginger essential oil.
Comparative example 2
This embodiment differs from embodiment 3 in that the mouth cleaning liquid is free of a ginger essential oil and free of a spearmint essential oil.
Comparative example 3
This embodiment differs from embodiment 3 in that the mouth-cleansing liquid is free of a ginger essential oil, free of a spearmint essential oil, and free of a mint essential oil.
1. The mouth cleaning liquid of the invention has the effect of refreshing the oral cavity
In order to truly illustrate the utility of the present invention with respect to the mouth wash, the mouth wash prepared in the above embodiments 1 to 5 was used in clinical trials, 160 cases were counted, wherein 90 cases were male and 70 cases were female. After 4 hours of use, 5 persons were asked to evaluate the test results, and it was considered that oral malodor was eliminated by 1 point, oral malodor was not eliminated by 0 point, oral malodor was eliminated by more than 3 points, and oral malodor was not eliminated by less than 3 points.
The invention provides a use method and dosage of the mouth cleaning liquid: the preparation is taken twice a day, 20ml is used once, and the preparation is kept in mouth for 1-2 minutes once.
Clinical trials showed that 160 patients were divided into 8 groups of 20 patients, and the results are shown in table 1:
TABLE 1
As can be seen from table 1, the oral cleansing liquids prepared according to embodiments 1 to 5 clinically used in 100 cases, 3 or more cases, and 86% or more cases; 11 cases divided by 1-2 account for 11%; 3 cases of 0 minute account for 3 percent, and the total effective rate is 86 percent.
20 of the mouth-cleansing liquid prepared in comparative mode 1 above, 3 out of 10, account for 50%; 1-2, accounting for 25% of 5 cases; 5 cases of 0 minute account for 25 percent, and the total effective rate is 50 percent.
20 of the mouth-cleansing liquid prepared in comparative mode 2 were used, and 3 of the mouth-cleansing liquid was divided into 9 or more cases, accounting for 45%; 6 cases divided into 1-2, accounting for 30%; 5 cases of 0 minute account for 25 percent, and the total effective rate is 45 percent.
20 examples of the mouth-cleansing liquid prepared in comparative example 3 were divided into 5 examples or more, and the divided amount of 3 was 25%; 4 cases divided by 1-2 account for 20%; 11 cases of 0 minute account for 55 percent, and the total effective rate is 25 percent.
It is explained that the mouth-cleansing liquid prepared in embodiments 1 to 5 of the present invention can clean the oral cavity, kill bacteria in the oral cavity, and keep fresh breath continuously. The mouth-cleaning liquid prepared by the comparison modes 1 to 3 has the total effective rate of not more than 50 percent, which shows that essential oil components such as the zingiber corallinum hance essential oil, the spearmint essential oil and the mint essential oil have better effect on keeping the oral cavity fresh.
2. The effect of the mouth cleaning liquid on common oral bacteria
The oral cleaning liquid prepared in the embodiment 1 to the embodiment 5 is used for detecting the bacteriostatic and anti-inflammatory effects on staphylococcus aureus, actinomyces viscosus and candida albicans;
2.1 tested strains including staphylococcus aureus (ATCC6538), actinomyces viscosus (ATCC19246) and candida albicans (ATCC76615), wherein the generation number of the strains is 4-6, and PBS containing 0.03 mol/L is used for preparing a strain suspension;
2.2 test method: the test is carried out according to appendix C of GB15979-2002 hygienic Standard for Disposable sanitary articles, and the test results are shown in Table 2:
TABLE 2
As can be seen from table 2, all of embodiments 1 to 5 have significant antibacterial effects against staphylococcus aureus, actinomyces viscosus and candida albicans. Staphylococcus aureus, actinomyces viscosus and candida albicans are common oral bacteria, and can cause common oral diseases, such as caries, periodontal disease, oral mucosis, dental calculus and the like. The mouth cleaning liquids prepared in embodiments 1 to 5 of the present invention have an inhibitory effect on the above flora, which indicates that they can inhibit dental plaque, thereby having an anti-calculus effect.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (10)
1. The mouth cleaning liquid is characterized by comprising the following raw materials in parts by mass: 2-6 parts of coral ginger essential oil, 1-5 parts of spearmint essential oil, 0.5-3.5 parts of mint essential oil, 2-5 parts of edible ethanol, 0.1-0.4 part of foaming agent, 0.01-0.04 part of edible preservative, 0.1-0.5 part of sweetening agent, 0.01-0.04 part of plant spice, 0.4-1.8 parts of sodium carbonate peroxide and 76-96 parts of water.
2. The mouth-cleaning liquid according to claim 1, which is characterized by comprising the following raw materials in parts by mass: 3-4 parts of coral ginger essential oil, 2-3 parts of spearmint essential oil, 0.8-2.2 parts of mint essential oil, 2.5-4 parts of edible ethanol, 0.2-0.3 part of foaming agent, 0.02-0.03 part of edible preservative, 0.2-0.4 part of sweetener, 0.02-0.03 part of plant spice, 0.5-1.3 parts of sodium percarbonate and 80-85 parts of water.
3. The mouth-cleaning liquid according to claim 1, which is characterized by comprising the following raw materials in parts by mass: 3 parts of coral ginger essential oil, 2.5 parts of spearmint essential oil, 1.5 parts of mint essential oil, 3 parts of edible ethanol, 0.25 part of foaming agent, 0.02 part of edible preservative, 0.3 part of sweetener, 0.02 part of plant spice, 0.8 part of sodium percarbonate and 84 parts of water.
4. The mouth cleaning liquid according to any one of claims 1 to 3, wherein the foaming agent is any one or a mixture of two or more of carbon dioxide, cocamidopropyl betaine and sodium lauryl sulfate; the edible preservative is potassium sorbate or sodium benzoate; the sweetener is xylitol or stevioside.
5. The mouth-cleaning liquid according to any one of claims 1 to 3, wherein the plant perfume is any one or a mixture of two or more of camellia powder, osmanthus powder and jasmine powder.
6. The mouth rinse of any one of claims 1-3, wherein the water is deionized water.
7. A preparation method of a mouth cleaning liquid is characterized by comprising the following steps:
s1, weighing the following raw materials in parts by mass: 2-8 parts of coral ginger essential oil, 1-5 parts of spearmint essential oil, 0.5-3.5 parts of mint essential oil, 2-5 parts of edible ethanol, 0.1-0.4 part of foaming agent, 0.01-0.04 part of edible preservative, 0.1-0.5 part of sweetening agent, 0.01-0.04 part of plant spice, 0.4-1.8 parts of sodium carbonate peroxide and 76-96 parts of water;
s2, adding a sweetening agent and sodium percarbonate into water, stirring and dissolving to obtain a solution A;
s3, mixing edible ethanol, essential oil of Zingiber corallinum Hance, essential oil of spearmint and essential oil of mint, and heating and stirring to obtain a solution B;
s4, slowly adding the solution B obtained in the step S3 into the solution A obtained in the step S2 under the stirring state, and uniformly mixing to obtain a solution C;
s5, adding the foaming agent, the edible preservative and the plant spice into the solution C obtained in the step S4, and then stirring, standing, filtering and carrying out sterile treatment to obtain the mouth cleaning liquid.
8. The method for preparing a mouth-cleansing liquid according to claim 7, wherein the foaming agent is any one or a mixture of two or more of carbon dioxide, cocamidopropyl betaine, and sodium lauryl sulfate in step S1; the edible preservative is potassium sorbate or sodium benzoate; the sweetener is xylitol or stevioside; the sweetener is xylitol or stevioside; the plant spice is any one or a mixture of more than two of camellia powder, sweet osmanthus powder and jasmine powder; the water is deionized water.
9. The method for preparing a mouth-cleansing liquid according to claim 7, wherein the heating temperature is 40 ℃ to 50 ℃ in step S3.
10. The method for preparing a mouth-cleansing liquid according to any one of claims 7 to 9, wherein the standing time in step S5 is 24 to 48 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010450123.0A CN111481474A (en) | 2020-05-25 | 2020-05-25 | Mouth cleaning liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010450123.0A CN111481474A (en) | 2020-05-25 | 2020-05-25 | Mouth cleaning liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111481474A true CN111481474A (en) | 2020-08-04 |
Family
ID=71790740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010450123.0A Withdrawn CN111481474A (en) | 2020-05-25 | 2020-05-25 | Mouth cleaning liquid and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111481474A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115590900A (en) * | 2022-10-10 | 2023-01-13 | 湖南循力源口腔疾病研究院有限公司（Cn） | Application of traditional Chinese medicine volatile oil in substances for preventing and treating halitosis |
-
2020
- 2020-05-25 CN CN202010450123.0A patent/CN111481474A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115590900A (en) * | 2022-10-10 | 2023-01-13 | 湖南循力源口腔疾病研究院有限公司（Cn） | Application of traditional Chinese medicine volatile oil in substances for preventing and treating halitosis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Niazi et al. | Role of Salvadora persica chewing stick (miswak): A natural toothbrush for holistic oral health | |
| CN104887581B (en) | A kind of oral care composition and preparation method thereof | |
| CN105770191B (en) | With the composition and its preparation method and application for reducing Periodontal Pathogens active function | |
| US7083779B2 (en) | Nontoxic dental care herbal formulation for preventing dental plaque and gingivitis | |
| CN103536497B (en) | A kind of Traditional Chinese medicinal compound collutory and preparation method thereof | |
| CN106924162B (en) | Plant additive, bacteriostatic agent, oral care product and application of plant additive in preparation of oral care product | |
| CN108815232A (en) | A kind of draft antimicrobial fluid | |
| CN108014070A (en) | Visualization propolis acidity mouthwash of hemostasis and anti-inflammation and preparation method thereof | |
| CN101181208B (en) | Gargle containing natural antibiotics and preparation method thereof | |
| KR101778058B1 (en) | Composition for sanitation promotion of oral cavity comprising natural medicinal ingredient extract as effective component for halitosis inducing microoranism and infectious disease of mucous membrane | |
| CN111481474A (en) | Mouth cleaning liquid and preparation method thereof | |
| CN108721180B (en) | Bacteriostatic oral composition containing honeysuckle, product and preparation method thereof | |
| CN103599182A (en) | Traditional Chinese medicine composition and preparation method thereof, and oral cavity cleaning and nursing product and preparation method thereof | |
| KR20140127061A (en) | Oral Hygiene functional composition and a method of manufacturing | |
| CN105997792A (en) | Traditional Chinese medicine mothproofing and tooth-protecting gargle and preparation method thereof | |
| CN111743790B (en) | Low-viscosity sea salt oral care mouth wash | |
| CN113520957A (en) | Chinese herbal medicine toothpaste formula for gingivitis and gingival atrophy and preparation method thereof | |
| CN107898705B (en) | A collutory for preventing dental caries and oral ulcer, and its preparation method | |
| Harput | Herbal products for oral hygiene: An overview of their biological activities | |
| KR20220099175A (en) | Oral composition comprising herbal complex | |
| KR20150040818A (en) | Oral Hygiene functional composition and a method of manufacturing | |
| KR20160084904A (en) | Composition for sanitation promotion of oral cavity comprising natural medicinal ingredient extract as effective component | |
| Khobragade et al. | Herbal Mouthwash for the Management of Oral Diseases: A Review on the Current Literature | |
| KR20180054533A (en) | Raspberry leaf fermentation, nasal cavity, oral, throat, skin, cleansing(gargle) beverages, The compositions of the manufacturing process | |
| CN108926636A (en) | A kind of plant bacteriostatic agent and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20200804 |
|
| WW01 | Invention patent application withdrawn after publication |