CN111450176A - Gynecological antibacterial gel - Google Patents

Gynecological antibacterial gel Download PDF

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Publication number
CN111450176A
CN111450176A CN201910088448.6A CN201910088448A CN111450176A CN 111450176 A CN111450176 A CN 111450176A CN 201910088448 A CN201910088448 A CN 201910088448A CN 111450176 A CN111450176 A CN 111450176A
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gynecological
gel
bacteriostatic gel
dandelion
safflower
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项中付
徐芳
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Shanghai Deshang Biomedical Technology Co ltd
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Shanghai Deshang Biomedical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/84Valerianaceae (Valerian family), e.g. valerian
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
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  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a gynecological bacteriostatic gel, and particularly relates to the technical field of biomedicine, wherein the bacteriostatic gel comprises the following raw materials in parts by weight: 30-60 g of dandelion, 30-60 g of safflower, 30-60 g of Chinese violet, 30-60 g of herba patriniae, 30-60 g of houttuynia cordata, 15-30 g of red peony root, 1000-2000 g of water and 200g of glycerol 100-. The herbal bacteriostatic gel disclosed by the invention is a pure natural Chinese herbal medicine preparation, has the functions of lasting long-acting antibiosis and removing peculiar smell, and has a special effect on female abnormal leucorrhea, vaginitis, pelvic effusion, pelvic inflammation, annexitis and cervical erosion. Meanwhile, the symptoms such as pruritus vulvae, abnormal leucorrhea, waist soreness, falling pain of lower abdomen and the like caused by pathological changes disappear obviously.

Description

Gynecological antibacterial gel
Technical Field
The invention relates to a gynecological antibacterial gel, and particularly relates to the technical field of biological medicines.
Background
The gynecological diseases seriously affect the physical health of women, and in the epidemiological investigation result of the gynecological common diseases, the sequence of the prevalence rate of genital tract infection is as follows: 39.3 percent of chronic cervicitis, 15.9 percent of vaginitis caused by various reasons, 5.4 percent of genital tract chlamydia trachomatis infection, 4.1 percent of chronic pelvic inflammation, 1.5 percent of vulvitis and the like.
According to statistics, more than 65% of adult women in China are often troubled by various gynecological diseases and are quite bitter. The main reason for the gynecological diseases is that women are easily attacked by pathogens such as candida albicans, staphylococcus aureus, streptococcus, escherichia coli, viruses and the like due to the influence of various factors such as the physiological structure, the living environment and the like of women; some patients have more serious infection due to weak self-protection consciousness and insufficient attention in the early stage of infection; in addition, due to poor living habits or high working pressure, the immunity of partial patients is poor, so that the gynecological diseases are not cured for a long time, and great inconvenience is brought to normal life.
At present, the medicines for treating gynecological inflammation are more, the main components of the oral medicine preparation are Chinese medicines and western medicines, the Chinese medicines and the western medicines enter the vagina part through gastrointestinal absorption and blood circulation and kill bacteria, the onset time is slow, and the oral medicine preparation generally has the curative effect only after long-term administration; in addition, antibacterial drugs for treating gynecological inflammation comprise suppositories, lotions, sprays and the like, but most of the drugs are not pure traditional Chinese medicine components and can destroy the reproductive tract environment and the mucous membrane self-secretion function, so that the local immunity of reproduction is reduced, pathogenic bacteria can generate drug resistance and drug resistance, and finally inflammation is repeatedly attacked; therefore, the research on a pure Chinese medicinal bacteriostatic medicament for preventing and treating gynecological diseases is needed.
Disclosure of Invention
The invention aims to provide a gynecological bacteriostatic gel.
In order to achieve the purpose, the invention provides the following technical scheme: the gynecological bacteriostatic gel comprises the following raw materials in weight by weight: 30-60 g of dandelion, 30-60 g of safflower, 30-60 g of Chinese violet, 30-60 g of herba patriniae, 30-60 g of houttuynia cordata, 15-30 g of red peony root, 1000-2000 g of water and 200g of glycerol 100-.
Further preferably, the gynecological bacteriostatic gel comprises the following raw materials in weight grams: 45g of dandelion, 45g of safflower, 45g of Chinese violet, 45g of patrinia, 45g of houttuynia cordata, 20g of red peony root, 1500g of water and 150g of glycerol.
A preparation method of gynecological bacteriostatic gel comprises the following steps:
step one, preparing materials, namely weighing the raw materials according to the weight gram of the gynecological antibacterial gel;
cleaning dandelion, safflower, Chinese violet, patrinia, houttuynia cordata and red paeony root, soaking for 1-2 hours, and then adding water for decocting for 2-3 hours to obtain a Chinese herbal medicine liquid;
step three, filtering the Chinese herbal medicine prepared in the step two to remove filter residues, and cooling to room temperature to obtain a semi-finished product;
step four: adding glycerol into the semi-finished product, stirring uniformly to obtain antibacterial gel, adding the antibacterial gel into a booster, inspecting and filling under aseptic condition, sealing in qualified interior, packaging in outer package, and warehousing in qualified area to be inspected.
Compared with the prior art, the invention has the following beneficial effects: the herbal bacteriostatic gel disclosed by the invention is a pure natural Chinese herbal medicine preparation, has the functions of lasting long-acting antibiosis and removing peculiar smell, and has a special effect on female abnormal leucorrhea, vaginitis, pelvic effusion, pelvic inflammation, annexitis and cervical erosion. Meanwhile, the symptoms such as pruritus vulvae, abnormal leucorrhea, waist soreness, falling pain of lower abdomen and the like caused by pathological changes disappear obviously.
Detailed Description
The technical solutions of the present invention will be described clearly and completely in the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a preparation method of gynecological bacteriostatic gel comprises the following steps:
step one, preparing materials, namely weighing the raw materials according to the weight gram of the gynecological antibacterial gel;
step two, cleaning and soaking 30g of dandelion, 30g of safflower, 30g of Chinese violet, 30g of patrinia, 30g of houttuynia cordata and 15g of red paeony root for 1 hour, and then adding 1000g of water to decoct for 2 hours to obtain Chinese herbal medicine liquid;
step three, filtering the Chinese herbal medicine prepared in the step two to remove filter residues, and cooling to room temperature to obtain a semi-finished product;
step four: adding 100g of glycerol into the semi-finished product, uniformly stirring to obtain the antibacterial gel, adding the antibacterial gel into a booster, inspecting and filling under an aseptic condition, sealing in a qualified inner mode, externally packaging, and warehousing the qualified area to be inspected.
Example 2:
a preparation method of gynecological bacteriostatic gel comprises the following steps:
step one, preparing materials, namely weighing the raw materials according to the weight gram of the gynecological antibacterial gel;
step two, cleaning 60g of dandelion, 60g of safflower, 60g of Chinese violet, 60g of herba patriniae, 60g of houttuynia cordata and 30g of red peony root, soaking for 2 hours, and then adding 2000g of water to decoct for 3 hours to obtain Chinese herbal medicine liquid;
step three, filtering the Chinese herbal medicine prepared in the step two to remove filter residues, and cooling to room temperature to obtain a semi-finished product;
step four: adding 200g of glycerol into the semi-finished product, uniformly stirring to obtain the antibacterial gel, adding the antibacterial gel into a booster, inspecting and filling under an aseptic condition, sealing in a qualified inner mode, carrying out outer packaging, and warehousing the qualified area to be inspected.
Example 3:
a preparation method of gynecological bacteriostatic gel comprises the following steps:
step one, preparing materials, namely weighing the raw materials according to the weight gram of the gynecological antibacterial gel;
step two, cleaning 45g of dandelion, 45g of safflower, 45g of Chinese violet, 45g of patrinia, 45g of houttuynia cordata and 20g of red paeony root, soaking for 1.5 hours, and then adding 1500g of water to decoct for 2.5 hours to obtain a Chinese herbal medicine liquid;
step three, filtering the Chinese herbal medicine prepared in the step two to remove filter residues, and cooling to room temperature to obtain a semi-finished product;
step four: adding 150g of glycerol into the semi-finished product, uniformly stirring to obtain the antibacterial gel, adding the antibacterial gel into a booster, inspecting and filling under an aseptic condition, sealing in a qualified inner mode, carrying out outer packaging, and warehousing the qualified area to be inspected.
The gynecological antibacterial gel prepared in example 1 is applied to 10 patients with gynecological inflammation, each patient continuously uses the antibacterial gel for four treatment courses, each treatment course is one week, and 8 patients have no symptoms such as waist soreness and abdomen pain.
The gynecological antibacterial gel prepared in example 2 is applied to 10 patients with gynecological inflammation, each patient continuously uses the antibacterial gel for four treatment courses, each treatment course is one week, and symptoms such as waist soreness and abdomen pain of 7 patients disappear.
The gynecological antibacterial gel prepared in example 3 is applied to 10 patients with gynecological inflammation, each patient continuously uses the antibacterial gel for four treatment courses, each treatment course is one week, and 9 patients have no symptoms such as waist soreness and abdomen pain. Therefore, the gynecological bacteriostatic gel has a good curative effect on gynecological nursing, and the embodiment is the best embodiment.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (3)

1. A gynecological bacteriostatic gel is characterized in that: the bacteriostatic gel comprises the following raw materials in weight grams: 30-60 g of dandelion, 30-60 g of safflower, 30-60 g of Chinese violet, 30-60 g of herba patriniae, 30-60 g of houttuynia cordata, 15-30 g of red peony root, 1000-2000 g of water and 200g of glycerol 100-.
2. A gynecological bacteriostatic gel according to claim 1, characterized in that: the gynecological bacteriostatic gel comprises the following raw materials in weight grams: 45g of dandelion, 45g of safflower, 45g of Chinese violet, 45g of patrinia, 45g of houttuynia cordata, 20g of red peony root, 1500g of water and 150g of glycerol.
3. A preparation method of gynecological bacteriostatic gel is characterized by comprising the following steps: the preparation method comprises the following steps:
step one, preparing materials, namely weighing the raw materials according to the weight gram of the gynecological antibacterial gel;
cleaning dandelion, safflower, Chinese violet, patrinia, houttuynia cordata and red paeony root, soaking for 1-2 hours, and then adding water for decocting for 2-3 hours to obtain a Chinese herbal medicine liquid;
step three, filtering the Chinese herbal medicine prepared in the step two to remove filter residues, and cooling to room temperature to obtain a semi-finished product;
step four: adding glycerol into the semi-finished product, stirring uniformly to obtain antibacterial gel, adding the antibacterial gel into a booster, inspecting and filling under aseptic condition, sealing in qualified interior, packaging in outer package, and warehousing in qualified area to be inspected.
CN201910088448.6A 2019-01-18 2019-01-18 Gynecological antibacterial gel Pending CN111450176A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113384645A (en) * 2021-07-30 2021-09-14 广州美懿医疗科技有限公司 Preparation method of gynecological gel with effects of clearing heat and activating blood circulation
CN113476581A (en) * 2021-07-20 2021-10-08 曌靓生物科技开发(上海)有限公司 Gynecological antibacterial liquid
CN113730482A (en) * 2021-09-17 2021-12-03 路焕喜 Gynecological antibacterial gel

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104721418A (en) * 2013-12-24 2015-06-24 葵花药业集团(伊春)有限公司 Pharmaceutical composition for treating gynecological inflammation and preparation method and use thereof
CN107468639A (en) * 2017-08-29 2017-12-15 厦门康心元聚生物科技有限公司 A kind of gynaecologic antibiotic gel and preparation method thereof
CN109419903A (en) * 2017-08-24 2019-03-05 李仁知 A kind of herbal retention enema liquid for treating gynaecological imflammation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104721418A (en) * 2013-12-24 2015-06-24 葵花药业集团(伊春)有限公司 Pharmaceutical composition for treating gynecological inflammation and preparation method and use thereof
CN109419903A (en) * 2017-08-24 2019-03-05 李仁知 A kind of herbal retention enema liquid for treating gynaecological imflammation
CN107468639A (en) * 2017-08-29 2017-12-15 厦门康心元聚生物科技有限公司 A kind of gynaecologic antibiotic gel and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
段红波等: ""中药治疗阴道病研究进展"", 《中国实验方剂学杂志》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113476581A (en) * 2021-07-20 2021-10-08 曌靓生物科技开发(上海)有限公司 Gynecological antibacterial liquid
CN113384645A (en) * 2021-07-30 2021-09-14 广州美懿医疗科技有限公司 Preparation method of gynecological gel with effects of clearing heat and activating blood circulation
CN113730482A (en) * 2021-09-17 2021-12-03 路焕喜 Gynecological antibacterial gel

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Application publication date: 20200728