CN107854542A - A kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof - Google Patents

A kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof Download PDF

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CN107854542A
CN107854542A CN201711182865.4A CN201711182865A CN107854542A CN 107854542 A CN107854542 A CN 107854542A CN 201711182865 A CN201711182865 A CN 201711182865A CN 107854542 A CN107854542 A CN 107854542A
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parts
preparation
hemorrhoid
chinese medicine
ointment
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龙步明
潘胜果
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Tuyun Guizhou Jiang Jiang Pharmaceutical Co Ltd
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Tuyun Guizhou Jiang Jiang Pharmaceutical Co Ltd
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

The invention discloses a kind of Chinese medicine preparation for treating inside and outside hemorrhoid, the Chinese medicine preparation is prepared by Radix Notoginseng powder, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf, fire numb grass, Mentholum, tetracycline ointment, erythromycin, metronidazole, vitamin and cooling ointment.The present invention has sterilization, hemostasis, antibacterial, anti-inflammation detumescence, antipruritic analgesic efficacy, effectively can be effectively improved and treat internal piles, external piles and mixed hemorrhoid, the scope of application of the present invention is wide, and treatment cycle is short.

Description

A kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof, belong to the field of medicine technology.
Background technology
Hemorrhoid（It is commonly called as hemorrhoid）It is a kind of common disease positioned at anus area, any age can all fall ill, but with the age Increase, the incidence of disease gradually increases.In China, hemorrhoid are most common anorectal diseases, are known as " ten male nine hemorrhoid ", " hemorrhoid of ten female ten " are said Method.In the U.S., the incidence of disease of hemorrhoid is about 5%.The cause of disease on hemorrhoid mainly has two kinds of theories.It is varicose vein theory first, it is believed that Hemorrhoid are the venous groups formed under distal rectal mucous membrane with veniplex extravasated blood, expansion and the flexing under anal canal skin.But at present Well accepted theory is Thomson anal cushions down theory, it is believed that hemorrhoid are originally the normal anatomical structure in anal tube position, i.e. blood Pipe pad, it is dentate line and above 1.5cm ring-type cavernous transformation taeniae telarum.Only anus pad tissue occurs exception and is associated with symptom When, hemorrhoid could be referred to as, just need to treat, therapeutic purposes are to release symptom, and non-elimination hemorrhoid body.The risk factor of hemorrhoid is a lot, its It is main inducing that middle constipation, long-term alcohol, a large amount of irritable foods of feed and sitting are stood long.
Hemorrhoid are divided into internal piles, external piles, mixed hemorrhoid by the difference of happening part.Have in the junction of anal canal skin and rectal mucosa One jagged visible line is anal tube dentate line.More than dentate line for internal piles, be support structure, the veniplex of anus pad And arteriovenous anastomosis Zhi Fasheng pathological changes or displacement, rectal mucosa is coated to, because internal sphincter shrinks, anus pad is with Y types ditch point Left side, forward right side and right lateral side are common in for left side, forward right side, three pieces of right lateral side, therefore internal piles；It is outer below dentate line Hemorrhoid, anal tube mucous membrane is coated to, connective tissue external piles, varicose external piles, thrombosed external hemorrhoid can be divided into；Have internal piles and external piles concurrently For mixed hemorrhoid, be that internal piles is merged by veniplex with corresponding external piles, i.e., upper and lower veniplex coincide, mixed hemorrhoid abjection anus When outdoors, in plum blossom-shaped, referred to as annular hemorrhoid, if by sphincter incarceration, strangulated hemorrhoid are formed.
The treatment method of hemorrhoid is broadly divided into operative treatment and non-operative treatment, non-operative treatment include topical therapy, Oral drug therapy, injection treatment, physical therapy and plastic loop ligation etc., wherein topical therapy has been widely adopted, medicine Including suppository, paste and lotion etc. the pharmaceutical preparation containing traditional Chinese medicine ingredients.Chinese medicine is particular about from outward appearance to inner essence, treated both principal and secondary aspect of disease, gentle, nothing Side effect and healing are thoroughly the traditional advantages of Chinese medicine.It is more to treat the medicine of hemorrhoid on the market at present, but mostly can only pin Internal piles or external piles are treated, not only therapeutic effect is poor, and the scope of application is narrower, and the cycle cured is longer.
So inventing, a kind of effect is good, and the healing cycle is short, and the Chinese medicine preparation of hemorrhoid has great importance inside and outside treatment.
The content of the invention
It is an object of the present invention to provide a kind of Chinese medicine preparation for treating inside and outside hemorrhoid.The present invention have sterilization, hemostasis, Antibacterial, anti-inflammation detumescence, antipruritic analgesic efficacy, it effectively can be effectively improved and treat internal piles, external piles and mixed hemorrhoid；The applicable model of the present invention Width is enclosed, treatment cycle is short.
Technical scheme：A kind of Chinese medicine preparation for treating inside and outside hemorrhoid, is calculated according to composition by weight, by Radix Notoginseng powder 5 ~ 20,10 ~ 20 parts of hairyvein agrimony, 15 ~ 30 parts of rde bean, 15 ~ 30 parts of japanese ophiorrhiza herb, 15 ~ 30 parts of loguat leaf, fire fiber crops are careless 10 ~ 25 parts, thin 5 ~ 20 parts of lotus ice, 10 ~ 25 parts of tetracycline ointment, 10 ~ 25 parts of erythromycin, 5 ~ 25 parts of metronidazole, vitamin B2It is 10 ~ 25 parts, refrigerant 5 ~ 15 parts of oil is prepared.
A kind of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, is calculated according to composition by weight, celestial by 10 ~ 15 parts of Radix Notoginseng powder 15 ~ 20 parts of crane grass, 20 ~ 25 parts of rde bean, 20 ~ 25 parts of japanese ophiorrhiza herb, 20 ~ 25 parts of loguat leaf, 15 ~ 20 parts of fire fiber crops grass, Mentholum 10 ~ 15 parts, 15 ~ 20 parts of tetracycline ointment, 15 ~ 20 parts of erythromycin, 10 ~ 20 parts of metronidazole, vitamin B215 ~ 20 parts, cooling ointment 10 ~ 15 parts are prepared.
A kind of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, is calculated according to composition by weight, by 12.3 parts of Radix Notoginseng powder, red crowned crane 18 parts of grass, 23 parts of rde bean, 22.4 parts of japanese ophiorrhiza herb, 22 parts of loguat leaf, 17.6 parts of fire fiber crops grass, 13.2 parts of Mentholum, tetracycline is soft 17.2 parts of cream, 17 parts of erythromycin, 16 parts of metronidazole, vitamin B217.5 parts, 12 parts of cooling ointment is prepared.
A kind of method of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, proportionally all medicinal materials in the side of weighing, and according to Conventional preparation method is processed, and corresponding pharmaceutical preparation is made.
A kind of preparation method of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, weighs each medicinal material, by celestial being according to prescription ratio Crane grass, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass are polished into powder respectively, and add Radix Notoginseng powder, Mentholum, erythromycin, first nitre Azoles and vitamin B2Hybrid process is carried out according to the preparation method and cooling ointment and tetracycline ointment of routine, corresponding medicine is made Preparation.
In a kind of preparation method of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, the pharmaceutical preparation is：Paste or suppository.
In a kind of preparation method of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, the paste is prepared：By hairyvein agrimony, Rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass be polished into powder respectively, and add Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and Vitamin B2Hybrid process is carried out according to the preparation method and cooling ointment and tetracycline ointment of routine, is produced.
In a kind of preparation method of foregoing Chinese medicine preparation for treating inside and outside hemorrhoid, the suppository is prepared：According to prescription Ratio weighs each medicinal material, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass is polished into powder respectively, and add pseudo-ginseng Powder, Mentholum, erythromycin, metronidazole and vitamin B2Preparation method according to routine is mixed with cooling ointment and tetracycline ointment Processing is closed, confection is made；Choose suppository and prepare conventional matrix and confection mixing, add inside bolt mould model, be poured into To die orifice is slightly overflowed in bolt mould, let cool, after complete solidification, cut with knife and overflow part, opened model, suppository is released, i.e., .
Medicine of the present invention is by Radix Notoginseng powder, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf, the numb grass of fire, Mentholum, Fourth Ring Plain ointment, erythromycin, metronidazole, vitamin B2 and cooling ointment are prepared.Wherein Radix Notoginseng powder is panax araliaceae plant Panax The powder that notoginseng (Burk.) F.H.Chen dry root and rhizome is worn into, have hemostasis, promoting blood circulation and removing blood stasis and detumescence fixed The effect of pain；Hairyvein agrimony alias fortune silene herb with root, melon vanilla, old Cowhells, wolf wheatgrass, Latin literary fame；Agrimonia pilosa Ledeb, its nature and flavor of hairyvein agrimony are bitter and put down, and have astringing to arrest bleeding, qi-restoratives, disperse accumulations, stop dysentery, desinsection, removing toxicity for detumescence and other effects, especially Anastalsis protrudes, and is used for the various disease conditions such as traumatism and bleeding, oozing of blood.Rde bean, Latin literary fame：Vigna umbellata (Thunb.) Ohwi et Ohashi are pulse family, Vigna annual herb, mainly with work(such as inducing diuresis for removing edema, removing toxic substances apocenosis Effect, it is usually used in controlling the normal blood of perianal abscess stool.Japanese ophiorrhiza herb is Thymelaeceae Edgeworthia chrysantha category, Latin literary fame：Edgeworthia chrysantha Lindl, it is warm-natured, taste micro-sweet and it is puckery, there is the effect of relaxing tendons and activating collaterals, anti-inflammatory analgetic, be usually used in promoting blood circulation for regulating menstruation, control traumatic injury. Loguat leaf (scientific name：Eriobotrya japonica Thunb.) also known as Ba Ye, Lu Juye, be rosaceous plant loquat leaf Son, its cold nature, bitter, there is the effect of removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, is usually used in treating cough with lung heat, circulation of vital energy in the wrong direction asthma suddenly, stomach energy is vomitted It is inverse, the illness such as dysphoria and thirsty.The numb grass of fire is a kind of annual herb plant of Urticaceae girardinia, Latin literary fame： Sceptrocnide macrostachya Maxim., its acrid flavour is warm-natured, has and dissipates the stasis of blood, hemostasis, the effect of calming the nerves, is usually used in Canker, dysphoria and traumatism and bleeding.Mentholum also known as menthol, it is to be obtained through refining by peppermint and obtained, can stimulates mucocutaneous, makes It is local that there is cool feeling, there is the effect of antipruritic, anti-inflammatory, analgesic, subside a swelling and stimulate circulation, be usually used in preparing cooling ointment, stop Pain medicine, toothpaste and spices.Tetracycline ointment main component is tetracycline, and chemical name is：6- methyl -4- (dimethylamino) -3, 6,10,12,12a- penta hydroxy group -1,11- dioxos-Isosorbide-5-Nitrae, 4a, 5,5a, 6,11,12a- octahydro -2- aphthacene formamides, molecule Formula is：C22H24N2O8, it is broad-spectrum antibacterial agent, has bactericidal action during high concentration, be usually used in sensitive gram positive bacteria, gram-negative bacteria Caused superficial skin infection.Erythromycin is a kind of alkaline antibiosis as caused by streptococcus Streptomyces erythreus Element, belong to macrolides, erythromycin system bacteriostatic agent, but also have bactericidal action to extremely sensitive bacterium in high concentration, chemistry It is entitled：5- (4- dimethylamine tetrahydrochysene -3- hydroxyl -6- methyl -2- pyrans epoxide) -6,11,12,13- tetrahydroxy -2,4,6,8, 1o, 12- hexamethyl -9- oxos -3- (tetrahydrochysene -5- hydroxyl -4- methoxyl group -4,6- dimethyl -2- pyrans epoxide) pentadecanoic acid-μ - Lactone, molecular formula are：C37H67NO13, it is a kind of white or yellowish white crystalline powder, odorless, bitter, there is suction in atmosphere It is moist, ethanol, chloroform, acetone and ether etc. are soluble in, is slightly soluble in water, to gram positive bacteria, such as staphylococcus, suppurative hammer Bacterium, viridans streptococci, streptococcus pneumonia, streptococcus fecalis, hemolytic streptococcus, clostridium, corynebacterium diphtheriae, bacillus anthracis Etc. there is stronger inhibitory action.Metronidazole is that creamy white crystals are obtained from from ethyl acetate, MP158-160 DEG C, micro- smelly, is slightly had Bitter saline taste, chemical name are：1- (2- ethoxys) -2- 5-nitro imidazoles;2- methyl-5-nitro -1H- imidazoles -1- second Alcohol, molecular formula are：C6H9N3O3, it is amebicide, antitrichomonal agent, antianaerobic-microbacterial drug, is the derivative of nitro glyoxaline, has There are anti-anaerobism protozoon and anaerobic bacteria, also have radiation-sensitive effect to the tumour cell of anoxic, be mainly used in treatment or pre- System or local infection caused by anti-anaerobic bacteria.Vitamin B2Riboflavin is called, chemical formula is：C17H20N4O6, major physiological work( By the use of being to promote to be metabolized as coenzyme, it is usually used in treating ulcer, hemorrhoid, angular stomatitis, cheilosis, glossitis, scrotitis, conjunctivitis, fat Property of overflowing dermatitis etc..Cooling ointment is also known as balm, is that one kind Bao He Nao ﹑ Zhang Nao ﹑ cassia bark You ﹑ eucalyptus oils etc. add cream made of paraffin Shape medicine, there is the effect of activating blood circulation and reducing swelling, antipruritic, and to staphylococcus, tubercle bacillus and common pathogenic skin Fungi has significant inhibitory action, is usually used in treating bite by mosquitos, pruitus or has minor scald.
Said medicine prescription, from Radix Notoginseng powder, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass, there is hemostasis The effect of dissipating the stasis of blood, sterilization detumescence and removing toxic substances apocenosis；It is aided with erythromycin, metronidazole and tetracycline ointment, there is antibacterial, anti-inflammatory and control Treat the effect of bacterium causes infection；Add vitamin B2, promote epiderm skin tissue growth, be advantageous to affected part healing；Add thin Lotus ice and cooling ointment, there is the effect of antibacterial anti-inflammatory, activating blood circulation and reducing swelling and antipruritic, and affected part can be made to feel refrigerant, mitigate Affected part pain, improve therapeutic effect；It is used cooperatively by above medicine, is had significantly for treatment internal piles, external piles and mixed hemorrhoid Effect.
The effect of the artificial checking present invention of application has carried out substantial amounts of experimental study, is below the knot of experimental study of the present invention Fruit：
Experimental example 1：Drug efficacy study
Treat example
Medicine used：Paste is made in method according to the embodiment of the present invention 1 and suppository is made in the method for embodiment 3.
Patient 1；Mrs Liu is 28 years old now, married.
Symptom：Anus side pain is uncomfortable, feels restless, inconvenient walking, occasionally has itch to conciliate and does not just feel only, per anum refers to Inspection, tentative diagnosis is external piles, it is seen that has 0.8cmX0.6cm connective tissue type external piles outside anus, is soft enclosed mass.
After paste provided by the present invention one week, connective tissue type external piles disappears, pain disappears, can normal sitting and lying row Walk.
Through patient's readme：
Medication first day, there is refrigerant sense, and pain is relieved, and itch disappears.
Medication the 3rd day, pain is greatly reduced, and sitting and lying, walking sense of discomfort are relieved.
Medication the 7th day, pain is wholly absent, can normally sitting and lying, walking, after inspection connective tissue type external piles disappear.
Patient 2；Mr. Zhang, 34 years old now, married, office staff.
Symptom：Anus pain, pain aggravates during defecation, difficult defecation, and just middle band blood, influences sitting and lying of normally walking, warp Check, tentative diagnosis is anus internal piles.
After suppository provided by the present invention one week, anus pain disappears, can normal defecation, without having blood in stool phenomenon, normally Walking, sitting and lying are unaffected.
Through patient's readme：
Medication first day, anus refrigerant sense, pain relief can defecation.
Medication the 3rd day, pain is greatly reduced, and sitting and lying, walking sense of discomfort are relieved, and defecation is smooth.
Medication the 7th day, anus pain is wholly absent, can normal defecation, without having blood in stool phenomenon, normal walking, sitting and lying be not by shadow Ring.
Patient 3；Mr. Long, 44 years old now.
Symptom：Intermittence is had blood in stool, and has polyp at anus, has pain during sitting and lying, pain of being hardened at anus, on inspection, just Step is diagnosed as mixed hemorrhoid.
After paste provided by the present invention one week, phenomenon of having blood in stool disappears, and polyp disappears at anus, without pain at anus Sense.
Through patient's readme：
Medication first day, anus refrigerant sense, sense of hardening reduce, pain relief.
Medication the 4th day, phenomenon of having blood in stool disappear, and polyp is obviously reduced at anus.
Medication the 7th day, phenomenon of having blood in stool disappear, and polyp disappears at anus, painless at anus.
Patient 4；Mr. He, 38 years old now.
Symptom：Have blood in stool serious, defecation pain, it is difficult to sitting and lying, have inflammation symptom at anus, tentative diagnosis is mixed hemorrhoid.
After paste provided by the present invention and suppository ten days, disappearance of having blood in stool, defecation without pain, can normal sitting and lying, anus Inflammation resolution of symptoms at door.
Through patient's readme：
Medication first day, there is refrigerant sense after smearing, slightly stimulated at anus, defecation pain relief.
Medication the 4th day, phenomenon of having blood in stool mitigate, and defecation pain relief, sitting and lying sense of discomfort is greatly reduced, inflammation disease at anus Shape mitigates.
Medication the 7th day, phenomenon of having blood in stool substantially, defecation without pain, can normal sitting and lying, inflammation symptom disappears substantially at anus.
Medication the tenth day, without having blood in stool phenomenon, can normal defecation, defecation without pain, can normal sitting and lying, inflammation symptom at anus Disappear completely.
Patient 5；Mrs Qian, 27 years old now.
Symptom：Fecal blood, painless, perianal often has itch uncomfortable, and tentative diagnosis is external piles.
After paste provided by the present invention three days, disappearance of having blood in stool, no itch phenomenon.
Through patient's readme：
Medication first day, there is refrigerant sense after smearing, itch phenomenon is relieved.
Medication second day, phenomenon of having blood in stool mitigate, and itch phenomenon disappears substantially.
Medication the 3rd day, disappearance of having blood in stool, no itch phenomenon.
Experimental example 2：Acute skin irritation test
Each 5 of Japan large ear rabbit male and female are selected, body weight 2kg~3kg, paste prepared by the embodiment of the present invention 1 are directly coated with On the right side of animal on skin, left side skin is as control, 5 hours application time, is remained after off-test with warm water washing tested Thing, 1h, 24h, 48h and 72h observe the dermoreaction of the tested area of animal and check plot respectively after removing tested material, and top is equal It is worth for " 0 ", judges that the medicine is nonirritant to animal skin.
Compared with prior art, the present invention is careless, thin from Radix Notoginseng powder, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf, fire fiber crops Lotus ice, tetracycline ointment, erythromycin, metronidazole, vitamin B2And cooling ointment, with sterilization, hemostasis, antibacterial, anti-inflammatory disappears Swollen, antipruritic analgesic efficacy, suitable for the patient of internal piles, external piles and mixed hemorrhoid, can improve and treat patient's hemorrhoid, manufactured medicine Evident in efficacy, treatment cycle is shorter, has no toxic side effect, and has reached goal of the invention.
The present invention is further illustrated by the following examples, but not as limitation of the present invention.
Embodiment
The present invention is further illustrated for example below, but is not intended as the foundation limited the present invention.
Embodiment 1.
Prescription：11 parts of Radix Notoginseng powder, 16 parts of hairyvein agrimony, 21 parts of rde bean, 21 parts of japanese ophiorrhiza herb, 21 parts of loguat leaf, fire fiber crops grass 16 Part, 10 parts of Mentholum, 16 parts of tetracycline ointment, 16 parts of erythromycin, 12 parts of metronidazole, vitamin B216 parts, 11 parts of cooling ointment.
Technique：Each medicinal material is weighed according to prescription ratio, by hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass respectively Powder is polished into, and adds Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and vitamin B2According to routine preparation method with it is refrigerant Oil and tetracycline ointment carry out hybrid process, and corresponding paste is made, produces.
Usage and dosage：External application, once in the morning and once at night（Use after an action of the bowels）, each 1.5g or so, first use light salt brine or height using preceding Potassium manganate solution cleans affected part, and paste is applied directly into affected part.
Embodiment 2.
Prescription：12.3 parts of Radix Notoginseng powder, 18 parts of hairyvein agrimony, 23 parts of rde bean, 22.4 parts of japanese ophiorrhiza herb, 22 parts of loguat leaf, fire fiber crops 17.6 parts of grass, 13.2 parts of Mentholum, 17.2 parts of tetracycline ointment, 17 parts of erythromycin, 16 parts of metronidazole, vitamin B217.5 part, 12 parts of cooling ointment.
Technique：Each medicinal material is weighed according to prescription ratio, by hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass respectively Powder is polished into, and adds Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and vitamin B2According to routine preparation method with it is refrigerant Oil and tetracycline ointment carry out hybrid process, and corresponding paste is made, produces.
Usage and dosage：External application, once in the morning and once at night（Use after an action of the bowels）, each 2g, light salt brine or potassium permanganate are first used using preceding Solution cleans anus, paste is transferred in standby ascending pipe, and ascending pipe is gently inserted in anus, squeezes into 2 grams or so medicines Cream.
Embodiment 3.
Prescription：14 parts of Radix Notoginseng powder, 20 parts of hairyvein agrimony, 24 parts of rde bean, 24 parts of japanese ophiorrhiza herb, 25 parts of loguat leaf, 19 parts of fire fiber crops grass are thin 14 parts of lotus ice, 20 parts of tetracycline ointment, 18 parts of erythromycin, 18 parts of metronidazole, vitamin B219 parts, 13 parts of cooling ointment.
Technique：Each medicinal material is weighed according to prescription ratio, by hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass respectively Powder is polished into, and adds Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and vitamin B2According to routine preparation method with it is refrigerant Oil and tetracycline ointment carry out hybrid process, and confection is made；Choose suppository and prepare conventional matrix and confection mixing, add Enter inside bolt mould model, be poured into bolt mould to die orifice is slightly overflowed, let cool, after complete solidification, cut with knife and overflow part, opened Model, suppository is released, produced.
Usage and dosage：External application, once in the morning and once at night（Use after an action of the bowels）, every 1.5g 1 tablet each time, using it is preceding first with light salt brine or Liquor potassic permanganate cleans anus, and suppository is filled in anus.

Claims (7)

  1. A kind of 1. Chinese medicine preparation for treating inside and outside hemorrhoid, it is characterised in that：Calculated according to composition by weight, it is celestial by Radix Notoginseng powder 5 ~ 20 10 ~ 20 parts of crane grass, 15 ~ 30 parts of rde bean, 15 ~ 30 parts of japanese ophiorrhiza herb, 15 ~ 30 parts of loguat leaf, 10 ~ 25 parts of fire fiber crops grass, Mentholum 5 ~ 20 parts, 10 ~ 25 parts of tetracycline ointment, 10 ~ 25 parts of erythromycin, 5 ~ 25 parts of metronidazole, vitamin B210 ~ 25 parts, cooling ointment 5 ~ 15 Part is prepared.
  2. 2. the Chinese medicine preparation of hemorrhoid inside and outside treatment according to claim 1, it is characterised in that：Calculated according to composition by weight, By 10 ~ 15 parts of Radix Notoginseng powder, 15 ~ 20 parts of hairyvein agrimony, 20 ~ 25 parts of rde bean, 20 ~ 25 parts of japanese ophiorrhiza herb, 20 ~ 25 parts of loguat leaf, fire fiber crops 15 ~ 20 parts of grass, 10 ~ 15 parts of Mentholum, 15 ~ 20 parts of tetracycline ointment, 15 ~ 20 parts of erythromycin, 10 ~ 20 parts of metronidazole, vitamin B215 ~ 20 parts, 10 ~ 15 parts of cooling ointment is prepared.
  3. 3. the Chinese medicine preparation of hemorrhoid inside and outside treatment according to claim 1, it is characterised in that：Calculated according to composition by weight, It is thin by 12.3 parts of Radix Notoginseng powder, 18 parts of hairyvein agrimony, 23 parts of rde bean, 22.4 parts of japanese ophiorrhiza herb, 22 parts of loguat leaf, 17.6 parts of fire fiber crops grass 13.2 parts of lotus ice, 17.2 parts of tetracycline ointment, 17 parts of erythromycin, 16 parts of metronidazole, vitamin B217.5 parts, 12 parts of systems of cooling ointment It is standby to form.
  4. 4. the method for the Chinese medicine preparation of hemorrhoid, its feature inside and outside a kind for the treatment of prepared as any one of claim 1-3 It is：Proportionally all medicinal materials in the side of weighing, and be processed according to the preparation method of routine, corresponding medicine system is made Agent.
  5. 5. the preparation method of the Chinese medicine preparation of hemorrhoid inside and outside treating according to claim 4, it is characterised in that：According to prescription ratio Example weigh each medicinal material, by hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass be polished into powder respectively, and add Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and vitamin B2Preparation method according to routine is mixed with cooling ointment and tetracycline ointment Processing, is made corresponding pharmaceutical preparation.
  6. 6. according to claim 4 or 5 it is described it is a kind of treat inside and outside hemorrhoid Chinese medicine preparation preparation method, it is characterised in that：Institute Stating pharmaceutical preparation is：Paste or suppository.
  7. A kind of 7. preparation method for the Chinese medicine preparation for treating inside and outside hemorrhoid according to claim 6, it is characterised in that：The cream Agent is prepared：Each medicinal material is weighed according to prescription ratio, hairyvein agrimony, rde bean, japanese ophiorrhiza herb, loguat leaf and fire fiber crops grass are beaten respectively Grinds, and add Radix Notoginseng powder, Mentholum, erythromycin, metronidazole and vitamin B2According to the preparation method and cooling ointment of routine Hybrid process is carried out with tetracycline ointment, corresponding paste is made.
CN201711182865.4A 2017-08-22 2017-11-23 A kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof Withdrawn CN107854542A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108888406A (en) * 2018-06-28 2018-11-27 江苏英科医疗制品有限公司 Hemorrhoid quickly cooling delays pain device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108888406A (en) * 2018-06-28 2018-11-27 江苏英科医疗制品有限公司 Hemorrhoid quickly cooling delays pain device

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