CN104208541B - A kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess and its application - Google Patents
A kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess and its application Download PDFInfo
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- CN104208541B CN104208541B CN201410421243.2A CN201410421243A CN104208541B CN 104208541 B CN104208541 B CN 104208541B CN 201410421243 A CN201410421243 A CN 201410421243A CN 104208541 B CN104208541 B CN 104208541B
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess, described Chinese medicine composition is made up of ichthyol ointment and washout prescription, and described washout prescription is mainly made up of the bulk drug of following parts by weight：25 35 parts of kuh-seng, 25 35 parts of smilax, raw 25 35 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）25 35 parts, peppermint（Under afterwards）8 12 parts.The hip bath of washout prescription is wiped dry after cleaning vulva, is taken appropriate ichthyol ointment to embrocate and is covered in Ipsilateral lump on labia majora lateral cutaneous, is applied to mucocutaneous intersection from outside to inside, takes mono layer gauze to fix isolation, in order to avoid medicine contamination underwear stimulation vulvar mucous membrane.The traditional Chinese medicine composition for treating cyst of Bartholin's gland and abscess significant effect of the present invention, simple and easy to do, safe, adverse reaction is few.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, is a kind of Chinese medicine group for treating cyst of Bartholin's gland and abscess specifically
Compound and its application.
Background technology
Cyst of Bartholin's gland system makes greater vestibular gland secretion drainage be obstructed because chronic inflammation stimulates obstruction anterior pituitary-adrenal cortex axis portion, point
Secretion gathers lower lumen of gland and causes body of gland cystic dilatation to cause tumour to be formed, and abscess is then formed after tumour is infected.Acute
Also tumour can be re-formed after fester is absorbed during inflammation infection.It is common in 20-40 year women.
Clinical manifestation be mostly it is unilateral also can the outer scrotum enclosed mass of bilateral, positioned at labia majora lower rear, to labia majora on the outside of
Direction protrudes.Check the lower half for finding that swollen thing be located at nymphae, ellipse, activity, when have labia swelling pain, it is local to send out
Heat, then there is fluctuation into purulence.Any symptom can be occurred without in a long time, be often found in gynecologial examination.Cysts grown
Relatively slowly, it is usually no more than egg size, small tumour is oval or fusiformis.Larger tumour can cause vulva falling inflation and property
Discomfort etc. is handed over, inspection can find that lump accounts for lower 1/3 position, nymphae in whole labia majora and is flattened completely, and introitus is pushed to
Strong side.Abscess can be formed during cyst of Bartholin's gland scabies secondary infection, repeated infection can expand tumour.
General treatment the lighter takes washout orally with Chinese herbal medicine, occurs together and uses antibiosis according to greater vestibular gland cultivation of cervical secretions when infecting
Extract for treating.But uncertain therapeutic efficacy is cut.Slightly larger person then based on operative treatment, is divided into simple puncture drainage and neostomy, Qian Zhefu
Hair rate is high, and the latter is made troubles to minimal invasive treatment and more pain, and implement more difficulty in acute stage, because abscess wall is easy
It is crisp to be not easy to suture.
Chinese patent literature CN103479834A discloses a kind of traditional Chinese medicine lotion for treating mass-type bartholinitis and prepared
Method, take 6 grams of Dysosma versipellis, barberry, christina loosestrife herb, subprostrate sophora, fig, cottonrose hibiscus flower, Lantana camara, phoenix-tail fern, beggar-ticks,
Herba Andrographitis, japanese white birch bark, kettle Lu, water chestnut, water shield, selfheal, dayflower, centella, stinkweed, river snail, radix ampelopsis, solanum lyratum, radix scrophulariae, half
Bian Lian, hypericum japonicum, ardisia crispa, Flabelate Maiden-hair Herb, the capsule of weeping forsythia, pin sand, Canton love-pea vine, adder-wort, cape jasmine, iron holly bark, chrysanthemum indicum, common alstonia bark or leaf, humulus
Grass and radix glycyrrhizae, above Chinese medicine is put into water and soaked, and then slow fire is fried, filter and remove residue, and fried decoction is to treat lump
The traditional Chinese medicine lotion of type bartholinitis.Chinese patent literature CN101797325A discloses a kind of medicine group for treating gynaecological imflammation
Compound, it is the medicine made of cockscomb, bark of tree of heaven, granatum, the Radix Astragali, the bighead atractylodes rhizome, Chinese yam and angelica, cuttle bone, madder is raw materials
Agent, the invention pharmaceutical composition reasonable recipe, meets traditional Chinese medical theory, has heat-clearing and damp-drying drug, replenishes qi to invigorate the spleen, the effect of stop-band,
Available for controlling for the gynaecological imflammations such as vaginitis, cervicitis, pelvic infecton, endometritis, adnexitis, vulvitis, bartholinitis
Treat, a kind of new medication selection is provided for clinic.But it is used to control with what washout prescription was used cooperatively on ichthyol ointment
The Chinese medicine composition for treating cyst of Bartholin's gland and abscess yet there are no report.
The content of the invention
The purpose of the present invention is to be directed to deficiency of the prior art, there is provided a kind of to treat in cyst of Bartholin's gland and abscess
Drug composition.
Another purpose of the present invention is to provide a kind of answering for Chinese medicine composition for treating cyst of Bartholin's gland and abscess
With.
To achieve the above object, the present invention adopts the technical scheme that：It is a kind of to treat in cyst of Bartholin's gland and abscess
Drug composition, described Chinese medicine composition are made up of ichthyol ointment and washout prescription, and described washout prescription is mainly by following
The bulk drug composition of parts by weight：Kuh-seng 25-35 parts, smilax 25-35 parts, raw tuber of stemona 25-35 parts, paniculate swallowwort 25-35 parts, peppermint
8-12 parts.
Described washout prescription is mainly made up of the bulk drug of following parts by weight：Kuh-seng 28-32 parts, smilax 28-32 parts,
Raw tuber of stemona 28-32 parts, paniculate swallowwort 28-32 parts, peppermint 9-11 parts.
Described washout prescription is mainly made up of the bulk drug of following parts by weight：30 parts of kuh-seng, 30 parts of smilax, the raw tuber of stemona
30 parts, 30 parts of paniculate swallowwort, 10 parts of peppermint.
Described washout prescription in preparation process after paniculate swallowwort and peppermint under.
To realize above-mentioned second purpose, the present invention adopts the technical scheme that：
Application of the described Chinese medicine composition in treatment cyst of Bartholin's gland and abscess medicine is prepared.
The invention has the advantages that：
The Chinese medicine composition for the treatment of cyst of Bartholin's gland and abscess provided by the invention, patient acceptance is high, low-cost,
Simple and easy to do, significant effect is safe, and adverse reaction is few.Quick, recurrence rate is low.
Embodiment
Embodiment provided by the invention is elaborated with reference to embodiment.
The present invention provides a kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess, by ichthyol ointment and washout group
Fang Zucheng, described washout prescription are mainly made up of the bulk drug of following parts by weight：Kuh-seng 25-35 parts, smilax 25-35 parts,
Raw tuber of stemona 25-35 parts, paniculate swallowwort（Under afterwards）25-35 parts, peppermint（Under afterwards）8-12 parts.
The washout prescription of embodiment 1
30 parts of kuh-seng, 30 parts of smilax, raw 30 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）30 parts, peppermint（Under afterwards）10 parts.
The washout prescription of embodiment 2
28 parts of kuh-seng, 32 parts of smilax, raw 28 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）32 parts, peppermint（Under afterwards）9 parts.
The washout prescription of embodiment 3
32 parts of kuh-seng, 28 parts of smilax, raw 32 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）28 parts, peppermint（Under afterwards）11 parts.
The washout prescription of embodiment 4
25 parts of kuh-seng, 35 parts of smilax, raw 25 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）35 parts, peppermint（Under afterwards）8 parts.
The washout prescription of embodiment 5
35 parts of kuh-seng, 25 parts of smilax, raw 35 parts of the tuber of stemona, paniculate swallowwort（Under afterwards）25 parts, peppermint（Under afterwards）12 parts.
The preparation of the washout prescription of embodiment 6
Any described washout prescriptions of embodiment 1-5, be 1g per parts by weight, add water 1000ml decoct soups, in preparation process slowly
Under after long minister in ancient times and peppermint.
The preparation of the washout prescription of embodiment 7
Any described washout prescriptions of embodiment 1-5, pass through any appropriate formulation made of conventional formulation means.
The clinical test of embodiment 8
1. data and method
1.1 clinical data
100 cysts of Bartholin's gland and abscess patient that in January, 2013 in June, 2014 goes to a doctor and made a definite diagnosis in the court, receive
Enter standard：(1) age 18-50 year, sexual intercourse history；(2) women of child-bearing age are same is intended to prohibit sexual life between treatment phase, is used during follow-up
Condom contraception person；(3) operative treatment is refused.Two groups are randomly divided into, treatment group 50, wherein light moderate 41, severe 9；
Control group 50, light moderate 42.Severe 8.Two groups of clinical data no significant difference (P>0.05).
1.2 treatment method
Treatment group：With reference to the washout prescription described in embodiment 1, kuh-seng 30g, smilax 30g, raw tuber of stemona 30g, paniculate swallowwort
（Under afterwards）30g, peppermint（Under afterwards）10g, add water 1000ml decoct soups.The hip bath of washout prescription is wiped dry after cleaning vulva, takes appropriate fish stone
Fat ointment is embrocated to be covered on labia majora lateral cutaneous in Ipsilateral lump, is applied to mucocutaneous intersection from outside to inside, is taken individual layer yarn
Cloth fixes isolation, in case medicine contamination underwear stimulates vulvar mucous membrane.
Points for attention：Because ichthyol ointment has certain excitant to mucous membrane, some patientss have mucosal irritation pain,
Pay attention to smearing along Ipsilateral groin ecto-entad when embrocating, no more than skin of labium majus mucous membrane intersection.
Control group：Potassium permanganate hip bath and oral western medicine are anti-infective, potassium permanganate hip bath one time a day, oral Ornidazole 0.5
G/ times, 2 times a day, and Norfloxacin 0.2g/ times, 2 times a day.
1.3 follow-up
Before treatment to be selected in the ordinary circumstance (age, height, weight) of patient, vital sign (body temperature, breathing, heart rate,
Blood pressure), past illness and history of operation, symptom and sign, severity extent, attack times etc. test and appraisal, and 1 week and 4 upon administration
Week carries out follow-up respectively.
1.4 observation items and index
(1) sings and symptoms.By the clinical symptoms and sign of patient, it is divided into light middle severe, capsule by tumour, abscess size
Swollen, abscess diameter<3 cm are slight, and 3-5 cm are moderate,>5 cm are severe；(2) laboratory examination.Before treatment, 1 after administration
All promoting circulation of blood routine urinalysis, hepatic and renal function inspection.Laboratory examination has abnormal person to need follow-up to normal after medication.Gestation is carried out before treatment
It is pregnant except experiment.
1.5 criterion of therapeutical effect
(1) clinical efficacy.According to the result of the 1st time and the 2nd time follow-up, point recovery from illness, take a turn for the better, invalid evaluation.Recovery from illness：Capsule
Swollen, abscess disappears.Without clinical symptoms.Take a turn for the better：Tumour, abscess reduce, and clinical symptoms improve.It is invalid：Tumour, abscess are without obvious contracting
Small, clinical symptoms change unobvious or exacerbation.(2) recurrence rate.After the 1st time and the 2nd follow-up, according to the clinical efficacy of patient
Effective number of cases.Calculate recurrence rate.Effective number of cases × 100% of 1 week after the failure number of cases/administration of 4 weeks after recurrence rate=administration
(after administration after the failure number of cases=administration of 4 weeks after effective number of cases-administration of l weeks effective number of cases of 4 weeks).
1.6 safety evaluatio
To patient before the treatment after hematological indices, hepatic and renal function and urine index change evaluate.
2. result
Two groups of Clinical efficacy comparisons after 2.1 treatments
Two groups of Clinical efficacy comparison results are as shown in table 1 after treatment, and effective percentage is significantly higher than after treatment group is administered 1 week, 4 weeks
Control group (P<0.05).
Two groups of recurrence rates compare after 2.2 treatments
Two groups of recurrence rate comparative results are as shown in table 2 after treatment, and treatment group's recurrence rate is substantially less than control group（P ＜
0.05）.
2.3 laboratory examination
The pretherapy and post-treatment every biochemical indicator testing result for the treatment of group is shown, has no obvious using this Chinese medicine composition patient
Adverse reaction.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as
Protection scope of the present invention.
Claims (5)
1. a kind of combination product for treating cyst of Bartholin's gland and abscess, it is characterised in that described combination product is by ammonium ichthosulfonate
Ointment and washout prescription composition, described washout prescription are made up of the bulk drug of following parts by weight：Kuh-seng 25-35 parts, smilax
25-35 parts, raw tuber of stemona 25-35 parts, paniculate swallowwort 25-35 parts, peppermint 8-12 parts.
2. combination product according to claim 1, it is characterised in that described washout prescription by following parts by weight raw material
Medicine is made：Kuh-seng 28-32 parts, smilax 28-32 parts, raw tuber of stemona 28-32 parts, paniculate swallowwort 28-32 parts, peppermint 9-11 parts.
3. combination product according to claim 1, it is characterised in that described washout prescription by following parts by weight raw material
Medicine is made：30 parts of kuh-seng, 30 parts of smilax, raw 30 parts of the tuber of stemona, 30 parts of paniculate swallowwort, 10 parts of peppermint.
4. according to the combination product described in claim any one of 1-3, it is characterised in that described washout prescription is in preparation process
Under after middle paniculate swallowwort and peppermint.
5. the combination product according to claim any one of 1-3 is in treatment cyst of Bartholin's gland and abscess medicine is prepared
Using.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410421243.2A CN104208541B (en) | 2014-08-26 | 2014-08-26 | A kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess and its application |
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| CN201410421243.2A CN104208541B (en) | 2014-08-26 | 2014-08-26 | A kind of Chinese medicine composition for treating cyst of Bartholin's gland and abscess and its application |
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| CN104208541A CN104208541A (en) | 2014-12-17 |
| CN104208541B true CN104208541B (en) | 2018-01-02 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103446446A (en) * | 2013-10-07 | 2013-12-18 | 宋静 | Preparation method of traditional Chinese medicine lotion for curing hot-toxic type bartholinitis |
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2014
- 2014-08-26 CN CN201410421243.2A patent/CN104208541B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103446446A (en) * | 2013-10-07 | 2013-12-18 | 宋静 | Preparation method of traditional Chinese medicine lotion for curing hot-toxic type bartholinitis |
Non-Patent Citations (2)
| Title |
|---|
| 中西医结合治疗前庭大腺囊肿临床观察;路旸等;《中国中医急症》;20130731;第22卷(第7期);1204-1206 * |
| 挂线疗法配合中药外洗治疗前庭大腺囊肿31例临床观察;王海霞;《光明中医》;20021231;第17卷(第103期);54 * |
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Granted publication date: 20180102 Termination date: 20190826 |