CN101347594B - Method for preparing Chinese medicine for treating kidney-yang deficiency type diarrhea - Google Patents
Method for preparing Chinese medicine for treating kidney-yang deficiency type diarrhea Download PDFInfo
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Abstract
The invention relates to a method for preparing traditional Chinese medicine used for treating kidney-Yang deficiency wane type diarrhoea, belonging to the technical field of preparation method of traditional Chinese medicine. Currently, kanamycin which has toxicity for auditory nerve and kidney is generally adopted to treat the kidney-Yang deficiency wane type diarrhoea. The method has the technical proposal that: the medicines such as fructus psoraleae, fructus alpiniae oxyphyllae, herba epimedii, rhizoma curculiginis, morinda officinalis, penis and teste of an ursine seal, common cnidium fruit, Chinese chive seed, actinolite, radix astragali, yam, atractylis ovata, sealwort, levant cotton root, nutmeg, lotus seed, gordon euryale seed, halloysitum rubrum, pomegranate rind, dark plum fruit, shizandra berry, saccharum granorum, Chinese date and liquorice are soaked for 30 minutes in 1,200ml water; and then decocted by slow fire; after the residue is filtered by gauze, the traditional Chinese medicine used for treating kidney-Yang deficiency wane type diarrhoea is obtained. The traditional Chinese medicine has the advantages that the liquid medicine of the traditional Chinese medicine has little toxicity and side effect and stable healing efficacy after being taken orally, and the disease is not easy to recur. Simultaneously, the toxicity and side effect caused by applying kanamycin, gentamycin and amikacin is avoided.
Description
Technical field
The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of kidney-yang deficiency type diarrhea more specifically.
Background technology
The treatment kidney-yang deficiency type diarrhea generally adopts aminoglycosides antibiotics at present: kanamycin, gentamycin, amikacin; Diarrhea: bismuth subcarbonate, paregoric, sulfasalazine etc.1. adopt kanamycin: this product is all toxic to acoustic nerve and kidney, and the former shows as tinnitus, hearing loss even permanent deafness; The latter shows as albuminuria, cylinderuria etc.2. adopt gentamycin: based on hearing impairment, the vestibule infringement is not obvious, and nephrotoxicity is stronger.3. adopt amikacin: nephrotoxicity and ear toxication certainly exist, and idol has nauseating, vomiting, headache, heating, erythra, trembles, paraesthesia, arthralgia, eosinophilia, anemia and hypotension etc.4. adopt bismuth subcarbonate: easily cause constipation and acidosis, take medicine afterwards to defecate and turn black.5. adopt paregoric: can cause constipation, nauseating, vomiting, dizzy, can cause morphinism in a large number.6. adopt sulfasalazine: allergy such as gastrointestinal symptom, erythra can be arranged.Have loose bowels, particularly summer diarrhea causes cross infection easily, as not causing large-area crowd's enteric infection that public health is caused very big threat by the disease control epidemic prevention.
Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of kidney-yang deficiency type diarrhea.Have loose bowels: be meant that defecation frequency increases, feces is thin, even gush as water sample.Gesture is delayed the person for letting out so that big loose stool is thin, and stool is rare clearly directly to descend the person for rushing down as water.Assertive evidence is called and lets out at " interior warp ", and " watery diarrhea " arranged, " watery diarrhea ", " lientery ", " watery diarrhea " etc.Difficult Classic has the branch of five kinds of diarrhea, and the Chinese Tang epoch are called " diarrhea ", general designation " having loose bowels " after the Song dynasty.The also with good grounds cause of disease or pathogenesis and be called " diarrhea due to summer-heat ", " large intestine is let out " person are though title is many, not from " having loose bowels " two words." the beautiful case of red platform have loose bowels door " pointed out: " person of letting out, as letting out also of water, gesture is still slow; The person of rushing down, little have a difference to gesture down like straight, and its disease then is so total say had loose bowels." kidney yang deficiency is after the prolonged illness, the damage kidney yang, or worn with age, YANG QI deficiency, dysfunction of the spleen in warming, dysfunction of the spleen in transportation and transformation is had loose bowels and cause." Jing Yue's complete work is had loose bowels " piece of writing is pointed out: " kidney is that stomach closes, the Yu Eryin that has one's ideas straightened out, so two just switchings, all the institute of kidney extremely, YANG QI deficiency in the modern kidney, decline of the fire from the gate of life then ... in the cloudy arrogant utmost point, promptly make us watery diarrhea incessantly also." symptom of kidney-yang deficiency type diarrhea is: having loose bowels, many abdominal part is had a pain before dawn, and borborygmus are promptly rushed down, peace then after letting out, coldness of the body with chills, soreness of the waist and knees, pale tongue, tongue is white, deep-thready pulse.Little enteral diarrhea in the modern medicine, the low property of pancreatic function diarrhoea, colonic diarrhea all belong to the category that motherland's medical science " is had loose bowels ".When the patient of kidney-yang deficiency type diarrhea checks, the character of feces, microscopy and chemical examination, very useful for the diarrheal diagnosis, be an indispensable inspection to the diarrhoea patient.General watery stool is not with pus and blood, amount greatly, and fat is arranged, and has or do not have stomachache, and no tenesmus mostly is little enteral diarrhea, or the low property of pancreatic function diarrhoea; The feces amount is few, and mucous or pus and blood often is a colonic diarrhea.Microscopy finds that fat drop and indigestion food may be little enteral diarrhea; Big enteral diarrhea often can be found red white corpuscle.
Its technical scheme is: get Fructus Psoraleae 12 weight portions, Fructus Alpiniae Oxyphyllae 9 weight portions, Herba Epimedii 9 weight portions, Rhizoma Curculiginis 9 weight portions, Radix Morindae Officinalis 6 weight portions, Testis et penis callorhini 9 weight portions, Fructus Cnidii 12 weight portions, Semen Allii Tuberosi 9 weight portions, Actinolitum 6 weight portions, the Radix Astragali 18 weight portions, Rhizoma Dioscoreae 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Rhizoma Polygonati 12 weight portions, Radix Gossypii 12 weight portions, Semen Myristicae 9 weight portions, Semen Nelumbinis 9 weight portions, Semen Euryales 9 weight portions, Halloysitum Rubrum 6 weight portions, Pericarpium Granati 9 weight portions, Fructus Mume 9 weight portions, Fructus Schisandrae Chinensis 6 weight portions, maltose 9 weight portions, Fructus Jujubae 9 weight portions and Radix Glycyrrhizae 6 weight portions, above 24 flavor medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, filter and remove residue, fried medicinal liquid is 600 milliliters, is the Chinese medicine of treatment kidney-yang deficiency type diarrhea.
The advantage of this invention is: this traditional Chinese medicine liquid manufacturing is simple, and the herbal toxic effect of making is little, oral after, good absorbing in digestive tract, and stable curative effect, be not easy the bounce-back.Kanamycin, gentamycin, the caused toxicity of amikacin have been avoided using simultaneously to acoustic nerve and kidney; Avoided using constipation and the acidosis that bismuth subcarbonate causes; Allergy such as gastrointestinal symptom that paregoric, sulfasalazine cause and erythra have been avoided using.This 9 flavor medicine multi-flavor suffering of Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Herba Epimedii, Rhizoma Curculiginis, Radix Morindae Officinalis, Testis et penis callorhini, Fructus Cnidii, Semen Allii Tuberosi, Actinolitum is warm in nature, all can go into kidney channel.Equal energy the kidney warming kidney invigorating and YANG supporting, wherein the double energy of Fructus Psoraleae controlling nocturnal emission with astringent drugs reducing urination is warming spleen and stopping diarrha; The double energy of Fructus Alpiniae Oxyphyllae is warming spleen and stopping diarrha, take the photograph saliva and spittle, controlling nocturnal emission with astringent drugs, urine reducing; The double energy of Herba Epimedii expelling wind and removing dampness, blood pressure lowering; The double energy of Rhizoma Curculiginis dispelling cold and dampness, bone and muscle strengthening; Radix Morindae Officinalis is held concurrently can bone and muscle strengthening, by cold-damp; The double energy of Testis et penis callorhini vital essence replenishing and marrow benifiting; The double energy of Fructus Cnidii killing parasites for relieving itching; Semen Allii Tuberosi is held concurrently can controlling nocturnal emission with astringent drugs.The equal sweet in the mouth of this 5 flavor medicine of the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, Radix Gossypii, property are flat or warm, all can go into spleen channel.All can invigorating the spleen and replenishing QI.Wherein the Radix Astragali hold concurrently can yang invigorating, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema; The double energy of Rhizoma Dioscoreae antidiarrheal, foster lung tonifying YIN, kidney tonifying Gu Jin, YIN nourishing and the production of body fluid promoting; The double energy of Rhizoma Atractylodis Macrocephalae dampness diuretic, strengthening superficial resistance to stop perspiration; The double energy of Rhizoma Polygonati nourishing YIN and moistening the lung; Radix Gossypii is held concurrently and can be invigorated blood circulation.In a word, benefit bone marrow, Fructus Alpiniae Oxyphyllae, Herba Epimedii, Rhizoma Curculiginis, Radix Morindae Officinalis, Testis et penis callorhini, Fructus Cnidii, Semen Allii Tuberosi, Actinolitum, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, this 14 flavor medical instrument of Radix Gossypii have the merit of warming the kidney to invigorate YANG, invigorating the spleen and benefiting QI, antidiarrheal.Because that " kidney master water ", " The spleen has the function to transport and transform nutrients " kidney get is warm, spleen must be mended, then have loose bowels from ending.In the process of treatment kidney-yang deficiency type diarrhea, play main therapeutical effect, so be monarch drug.Semen Myristicae, Semen Nelumbinis, Semen Euryales, Halloysitum Rubrum, Pericarpium Granati, this 6 flavor medicine of Fructus Mume belong to astringent medicinal.So-called " loose and receive it ", " puckery can taking off admittedly " promptly refer to the medicine of astringent therapy.Compendium of Material Medica is said: " take off then and to loose and do not receive, so with sour and astringent medicine, to hold back its dissipation ".This 6 flavor medicine all can relieving diarrhea with astringents.Wherein hold concurrently can warming middle-JIAO to promote flow of QI for Semen Myristicae; Semen Nelumbinis, the energy tranquilizing by nourishing the heart of holding concurrently, supplementing the kidney to control the nocturnal; The spleen invigorating of the double energy of Semen Euryales, supplementing the kidney to control the nocturnal, damp eliminating leukorrhagia stopping; Halloysitum Rubrum doublely can be held back blood hemostasis, promoting tissue regeneration and wound healing; The double energy of Pericarpium Granati parasite killing; The double energy of Fructus Mume astringing lung-QI and relieving cough, easing the stomach to subdue the ascarids, solid lower hemostasia, promoting the production of body fluid to quench thirst.In a word, this 6 flavor medicine plays the auxiliary treatment effect, so be ministerial drug in the process of treatment kidney-yang deficiency type diarrhea.The Fructus Schisandrae Chinensis sour in the mouth is warm in nature.Go into lung, the heart, kidney channel.Astringing lung-QI and relieving cough, consolidating superficial resistance arresting sweating, arresting seminal emission antidiarrheal, promoting the production of body fluid to quench thirst.This product is longer than the convergence lung qi and kidney nourishing water; The maltose sweet in the mouth, tepor.Go into spleen, stomach, lung meridian.The slow pain of spleen reinforcing, nourishing the lung to arrest cough.Because the merit of Fructus Schisandrae Chinensis, maltose Bearberry Extract, slow pain is so be adjuvant drug.The Fructus Jujubae sweet in the mouth is warm in nature.Go into spleen, kidney, the heart, Liver Channel.Spleen reinforcing and battalion, beneficial blood hemostasis, tranquilizing by nourishing the heart, the mitigation property of medicine; The Radix Glycyrrhizae sweet in the mouth is flat.Go into 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Fructus Jujubae, Radix Glycyrrhizae two flavors can be alleviated the toxicity of all medicines, can correct the bias of all medicines again, so be messenger drug.Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Herba Epimedii, Rhizoma Curculiginis, Radix Morindae Officinalis, Testis et penis callorhini, Fructus Cnidii, Semen Allii Tuberosi, Actinolitum, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, Radix Gossypii, Semen Myristicae, Semen Nelumbinis, Semen Euryales, Halloysitum Rubrum, Pericarpium Granati, Fructus Mume, Fructus Schisandrae Chinensis, maltose, Fructus Jujubae, Radix Glycyrrhizae.This 24 flavor medicine compatibility is used has warming the kidney to invigorate YANG, and the effect of invigorating the spleen and replenishing QI, relieving diarrhea with astringents, cold relieving pain relieving is the optimum formula of treatment kidney-yang deficiency type diarrhea.Fructus Psoraleae: hot, bitter, puckery, warm.Go into kidney, spleen channel.Kidney invigorating and YANG supporting, the controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha.Fructus Alpiniae Oxyphyllae: suffering, temperature.Go into spleen, kidney channel.Warming spleen and stopping diarrha, take the photograph saliva and spittle, tonifying the kidney to consolidate the essence, urine reducing.Herba Epimedii: hot, sweet, temperature.Go into liver, kidney channel.Kidney invigorating and YANG supporting dispels the wind and removes temperature, blood pressure lowering.Rhizoma Curculiginis: hot, hot.Go into kidney channel.Warming the kidney to invigorate YANG, dispelling cold and dampness, bone and muscle strengthening.Radix Morindae Officinalis: hot, sweet, tepor.Go into kidney channel.Kidney invigorating and YANG supporting, bone and muscle strengthening is by cold-damp.Testis et penis callorhini: salty, heat.Go into kidney channel.Warming the kidney to invigorate YANG, vital essence replenishing and marrow benifiting.Fructus Cnidii: hot, bitter, temperature.Go into kidney channel.Warming the kidney to invigorate YANG, killing parasites for relieving itching.Semen Allii Tuberosi: hot, sweet, temperature.Go into liver, kidney channel.The kidney warming controlling nocturnal emission with astringent drugs.Actinolitum: salty, temperature.Go into kidney channel.Warming the kidney to invigorate YANG.The Radix Astragali: sweet, temperature is gone into spleen, lung meridian, tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema.Rhizoma Dioscoreae: sweet, flat.Go into spleen, lung, kidney channel.Spleen reinforcing antidiarrheal is supported the lung tonifying YIN, kidney tonifying Gu Jin, YIN nourishing and the production of body fluid promoting.The Rhizoma Atractylodis Macrocephalae: sweet, bitter, warm, go into spleen, stomach warp.Invigorating the spleen and replenishing QI, dampness diuretic, strengthening superficial resistance to stop perspiration.Rhizoma Polygonati: sweet, flat.Go into spleen, lung, kidney channel.Invigorating the spleen and replenishing QI, nourishing YIN and moistening the lung.Radix Gossypii: sweet, warm.Go into spleen, liver, lung meridian.Inrigorating qi and promoting blood circulation.Semen Myristicae: hot, warm.Go into spleen, stomach, large intestine channel.Relieving diarrhea with astringents, warming middle-JIAO to promote flow of QI.Semen Nelumbinis: sweet, puckery, flat.Go into spleen, kidney, heart channel.Spleen reinforcing antidiarrheal, tranquilizing by nourishing the heart, supplementing the kidney to control the nocturnal.Semen Euryales: sweet, puckery, flat.Go into spleen, kidney channel.Invigorating the spleen to arrest diarrhea, supplementing the kidney to control the nocturnal, damp eliminating leukorrhagia stopping.Halloysitum Rubrum: sweet, sour, puckery, temperature.Go into kidney, large intestine channel.Relieving diarrhea with astringents is held back the blood hemostasis, promoting tissue regeneration and wound healing.Pericarpium Granati: sour, puckery, warm.Go into liver, stomach, large intestine channel.Relieving diarrhea with astringents, parasite killing.Fructus Mume: sour, puckery, flat.Go into lung, spleen, large intestine channel.Astringing lung-QI and relieving cough, relieving diarrhea with astringents, easing the stomach to subdue the ascarids, Gu lower hemostasia, promoting the production of body fluid to quench thirst.Fructus Schisandrae Chinensis: acid, temperature.Go into lung, the heart, kidney channel.Astringing lung-QI and relieving cough, consolidating superficial resistance arresting sweating, arresting seminal emission antidiarrheal, promoting the production of body fluid to quench thirst.Maltose: sweet, tepor.Go into spleen, stomach, lung meridian.The slow pain of spleen reinforcing, nourishing the lung to arrest cough.Fructus Jujubae: Gan Wen.Go into spleen, stomach, the heart, Liver Channel.Spleen reinforcing He Ying, beneficial blood hemostasis, tranquilizing by nourishing the heart, the mitigation property of medicine.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the property of medicine that is in harmonious proportion.
The specific embodiment
Get Fructus Psoraleae 12g, Fructus Alpiniae Oxyphyllae 9g, Herba Epimedii 9g, Rhizoma Curculiginis 9g, Radix Morindae Officinalis 6g, Testis et penis callorhini 9g, Fructus Cnidii 12g, Semen Allii Tuberosi 9g, Actinolitum 6g, Radix Astragali 18g, Rhizoma Dioscoreae 15g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Polygonati 12g, Radix Gossypii 1g, Semen Myristicae 9g, Semen Nelumbinis 9g, Semen Euryales 9g, Halloysitum Rubrum 6g, Pericarpium Granati 9g, Fructus Mume 9g, Fructus Schisandrae Chinensis 6g, maltose 9g, Fructus Jujubae 9g and Radix Glycyrrhizae 6g, above 24 flavor medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, filter and remove residue, fried medicinal liquid is 600 milliliters, is the Chinese medicine of treatment kidney-yang deficiency type diarrhea.When the kidney-yang deficiency type diarrhea patient need treat, each 200 milliliters oral, three times on the one, fluid temperature is 32 ℃, five is a course of treatment, if still have symptom such as have loose bowels to obey for second course of treatment again, so that recovery from illness.
Among the 219 routine kidney-yang deficiency type diarrhea patients, male's 151 examples account for 68.95%, and women's 68 examples account for 31.05%, and the male is more than the women.
The range of age of table one, 219 routine kidney-yang deficiency type diarrhea patients
| Age | 35～40 years old | 46～55 years old | 56～66 years old | 67～81 years old |
| The example number | 3 | 52 | 129 | 35 |
| Percentage ratio | 1.37％ | 23.75％ | 58.9％ | 15.98％ |
Information slip before and after table two, the 219 routine kidney-yang deficiency type diarrhea patient
Table three, 219 routine kidney-yang deficiency type diarrhea patients show the course of treatment
| The treatment natural law | 5～10 | 11～20 | 21～30 | 31～52 |
| The example number | 19 | 161 | 36 | 3 |
| Percentage ratio | 8.68％ | 73.51％ | 16.44％ | 1.37 |
Claims (1)
1. Chinese medicinal preparation method for the treatment of kidney-yang deficiency type diarrhea, it is characterized in that: get Fructus Psoraleae 12 grams, Fructus Alpiniae Oxyphyllae 9 grams, Herba Epimedii 9 grams, Rhizoma Curculiginis 9 grams, Radix Morindae Officinalis 6 grams, Testis et penis callorhini 9 grams, Fructus Cnidii 12 grams, Semen Allii Tuberosi 9 grams, Actinolitum 6 grams, the Radix Astragali 18 grams, Rhizoma Dioscoreae 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Rhizoma Polygonati 12 grams, Radix Gossypii 1 gram, Semen Myristicae 9 grams, Semen Nelumbinis 9 grams, Semen Euryales 9 grams, Halloysitum Rubrum 6 grams, Pericarpium Granati 9 grams, Fructus Mume 9 grams, Fructus Schisandrae Chinensis 6 grams, maltose 9 grams, Fructus Jujubae 9 grams and Radix Glycyrrhizae 6 grams, above 24 flavor medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, filter and remove residue, fried medicinal liquid is 600 milliliters, is the Chinese medicine of treatment kidney-yang deficiency type diarrhea.
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| CN103005104B (en) * | 2012-12-27 | 2014-06-25 | 青岛华仁技术孵化器有限公司 | Boxthorn leaf traditional Chinese medicine health tea for preventing and curing lung-kidney yin deficiency and preparation method thereof |
| CN103356986A (en) * | 2013-07-18 | 2013-10-23 | 苏州市天灵中药饮片有限公司 | Spleen-warming and diarrhea-stopping pills, and preparation method thereof |
| CN104383490A (en) * | 2014-11-20 | 2015-03-04 | 王正琦 | Traditional Chinese medicine composition for treating deficiency of yang |
| CN104645298A (en) * | 2015-03-05 | 2015-05-27 | 于巧媛 | Traditional Chinese medicine for treating kidney deficiency-type diarrhea disease |
| CN105194587A (en) * | 2015-11-11 | 2015-12-30 | 尹柱良 | Traditional Chinese medicine oral liquid for treating kidney yang deficiency and preparation method |
| CN106511648A (en) * | 2016-12-09 | 2017-03-22 | 河池市技术开发中心 | Traditional Chinese medicine composition for treating lamb diarrhea disease and preparation method of traditional Chinese medicine composition |
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| CN1876171A (en) * | 2006-04-20 | 2006-12-13 | 林莲球 | Soup formulation medicine for treating kidney deficiency type chronic alvine flux and preparation method thereof |
| CN101199774A (en) * | 2006-12-15 | 2008-06-18 | 天津市中宝制药有限公司 | Medicament for treating diarrhea |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1876171A (en) * | 2006-04-20 | 2006-12-13 | 林莲球 | Soup formulation medicine for treating kidney deficiency type chronic alvine flux and preparation method thereof |
| CN101199774A (en) * | 2006-12-15 | 2008-06-18 | 天津市中宝制药有限公司 | Medicament for treating diarrhea |
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Inventor after: Leng Jiajun Inventor after: Li Hui Inventor after: Liu Lida Inventor after: Wang Jinfeng Inventor before: Leng Jiajun |
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