CN111388579A - Medicine for enhancing memory - Google Patents
Medicine for enhancing memory Download PDFInfo
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- CN111388579A CN111388579A CN202010342326.8A CN202010342326A CN111388579A CN 111388579 A CN111388579 A CN 111388579A CN 202010342326 A CN202010342326 A CN 202010342326A CN 111388579 A CN111388579 A CN 111388579A
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- 239000003814 drug Substances 0.000 title claims abstract description 31
- 230000015654 memory Effects 0.000 title claims abstract description 14
- 229940079593 drug Drugs 0.000 title claims abstract description 9
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 235000011996 Calamus deerratus Nutrition 0.000 claims abstract description 6
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 6
- 239000002775 capsule Substances 0.000 claims abstract description 5
- 239000000843 powder Substances 0.000 claims description 11
- 238000001035 drying Methods 0.000 claims description 8
- 244000197580 Poria cocos Species 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- 230000006883 memory enhancing effect Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 241001080798 Polygala tenuifolia Species 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000007605 air drying Methods 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 claims description 2
- 238000011049 filling Methods 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims description 2
- 240000008167 Calamus deerratus Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 28
- 206010011878 Deafness Diseases 0.000 abstract description 6
- 208000009205 Tinnitus Diseases 0.000 abstract description 6
- 231100000895 deafness Toxicity 0.000 abstract description 6
- 208000016354 hearing loss disease Diseases 0.000 abstract description 6
- 231100000886 tinnitus Toxicity 0.000 abstract description 6
- 244000205574 Acorus calamus Species 0.000 abstract description 5
- 208000002173 dizziness Diseases 0.000 abstract description 5
- 230000001939 inductive effect Effects 0.000 abstract description 3
- 208000018997 giddiness Diseases 0.000 abstract description 2
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- 206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241000208966 Polygala Species 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 4
- 230000036770 blood supply Effects 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 230000002490 cerebral effect Effects 0.000 description 3
- 210000002216 heart Anatomy 0.000 description 3
- 230000004793 poor memory Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229940126680 traditional chinese medicines Drugs 0.000 description 3
- 230000002936 tranquilizing effect Effects 0.000 description 3
- 239000008187 granular material Substances 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000007963 capsule composition Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000007786 learning performance Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000013707 sensory perception of sound Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for enhancing memory, which is prepared by taking calamus, keel, tuckahoe and polygala root as raw materials according to a certain weight ratio. It can be made into capsule or tablet, and has effects of improving memory, inducing resuscitation, and treating giddiness, deafness and tinnitus caused by cerebral ischemia, with rapid onset of drug action and no adverse side effects.
Description
Technical Field
The invention relates to a medicine for enhancing memory, which is prepared from pure Chinese herbal medicines and belongs to the technical field of preparation of traditional Chinese medicines.
Background
With the development of times and the continuous improvement of living standard, brain workers increasingly have the phenomenon of memory reduction, and the memory reduction is the most common symptom of the brain workers, so that the working efficiency is low;
students also belong to the category of mental workers, the learning pressure is high, the learning performance is not good, the learning achievement is not good, and some reasons are not because the students are not diligent but the memory is not high, so many parents are also very worried;
and the middle-aged and elderly people also increasingly interfere with normal life along with the increase of the years and the problems of dizziness, deafness, tinnitus and the like caused by forgetfulness and insufficient cerebral blood supply.
At present, no specific medicine aiming at the symptom exists in the market, and aiming at the problems, a specific medicine which is quick to take effect and has no side effect is specially developed, and the medicine has the effects of enhancing the memory and simultaneously has the curative effects of inducing resuscitation and treating dizziness, deafness, tinnitus and the like caused by insufficient cerebral blood supply.
Disclosure of Invention
The present invention is directed to overcoming the above problems of the prior art and providing a memory enhancing drug.
The invention is realized by the following technical scheme. A medicine for enhancing memory is prepared from the following raw material medicines in parts by weight:
10-15 parts of calamus, 15-18 parts of keel, 9-14 parts of poria cocos and 12-15 parts of polygala tenuifolia;
the raw material medicaments and the dosage formula are obtained by clinical tests of the inventor for many years, and have obvious curative effect within the dosage range.
The medicine is prepared from pure traditional Chinese medicines, has no toxic or side effect, is suitable for children and adults to take, and has the advantages of quick response, obvious effect, effect taking effect within 3-5 days after continuous taking and the like through years of clinical tests.
The medicine can be prepared into oral administration dosage forms by adopting a conventional method of Chinese medicine preparations. The medicine can be prepared into powder by grinding the raw materials and uniformly mixing the powder, the pill, the tablet, the granule and the like, does not influence the treatment effect, and does not limit the protection scope of the invention.
The following capsule formulations are preferred for use in the present invention.
The preparation method of the medicine comprises the following steps:
(1) weighing raw materials in proportion, cleaning with clear water, and air drying for use;
(2) heating, drying and sterilizing the raw materials in the step (1) and cooling to room temperature;
(3) crushing the powder obtained in the step (2) and sieving the powder;
(4) and (4) filling the sieved medicinal powder in the step (3) into capsules.
Preferably, the heating and drying temperature in the step (2) is within the range of 100 ℃ to 150 ℃.
Preferably, the mesh number of the sieve used in the step (3) is 200 meshes.
The method comprises the following steps: cortex et radix Polygalae is pungent and warm, enters heart, lung and kidney meridians, has effects of coordinating heart and kidney, tranquilizing mind, replenishing vital essence and nourishing brain, and is used as a monarch agent for enhancing memory; rhizoma Acori Calami is pungent and warm, and has effects of inducing resuscitation, improving hearing and eyesight, tranquilizing mind and improving intelligence; os Draconis has effects of tranquilizing mind and astringing vital essence; the dragon bone and the calamus are used together, so that the dragon bone, the calamus and the dragon bone are scattered and collected one by one, are mutually coordinated, promote mental traffic and are used as ministerial drugs together; poria cocos, Poria cocos.
The four medicines are combined to play the roles of nourishing the heart, soothing the nerves, strengthening the essence and promoting the intelligence together, thereby achieving the effect of improving the memory.
The invention has the beneficial effects that:
the medicine for enhancing the memory provided by the invention has the advantages of simple and convenient processing and no need of decoction;
the traditional Chinese medicine is compatible with pure traditional Chinese medicines, has no toxic or side effect, and is suitable for children and adults to take;
has the advantages of quick response, obvious effect and 3-5 days of effect after continuous administration.
Detailed Description
The effect of the present invention will be further illustrated by the following examples and clinical application statistics.
Example 1: capsule preparation
Washing 15g of calamus, 18g of keel, 12g of poria cocos and 15g of polygala tenuifolia with clear water, drying in the air, drying and sterilizing by a drying device, wherein the drying temperature is 120-140 ℃, cooling to room temperature, crushing into powder by a crushing device, sieving by a 200-mesh sieve, and encapsulating the sieved powder with about 0.45g of medicinal powder per granule.
Clinical observation of the drug of the invention
General conditions and test methods
The invention of the formula of the medicine is invented from 2003, and long-term verification and final prescription modification are carried out, so that in order to prove the clinical curative effect of the medicine, the inventor carries out the following tests from 4 months in 2014 to 6 months in 2018, and divides the medicine into an immature group and an adult group, wherein the immature group is 8 to 16 years old, and the immature group has poor memory; the adult group is 25-58 years old, has poor memory, and symptoms such as giddiness, deafness and tinnitus caused by cerebral blood supply insufficiency, and has total number of 60, 35 of the underage group and 25 of the adult group.
The capsules of the medicine in the example 1 are taken by children 2 to 3 g each time, 3 times a day; 4-5 g for adult, 3 times daily.
Second, clinical observation criteria
The curative effect standard is as follows: the four main symptoms of dizziness, deafness, tinnitus and poor memory are all disappeared to show effect; vertigo, deafness, tinnitus and hypomnesis symptoms disappear at least one or the above main symptoms are obviously relieved; the four main symptoms before and after treatment were unchanged as no effect.
Third, analysis of therapeutic effects
43 cases of significant effect, 15 cases of effective effect, 2 cases of ineffective effect and 71.7 percent of significant effect rate.
It is emphasized that no side effect is found in the treatment group, and the effect standard can be achieved by continuously taking the medicine.
The embodiments selected for the purpose of disclosing the invention are presently considered to be suitable, however, it should be understood that the invention is intended to cover all variations and modifications of the embodiments falling within the spirit and scope of the present inventive concept.
Claims (4)
1. The medicine for enhancing the memory is characterized by being prepared from the following raw material medicines in parts by weight:
10-15 parts of calamus, 15-18 parts of keel, 9-14 parts of poria cocos and 12-15 parts of polygala tenuifolia.
2. A process for preparing a memory-enhancing pharmaceutical according to claim 1, which comprises the steps of:
(1) weighing raw materials in proportion, cleaning with clear water, and air drying for use;
(2) heating, drying and sterilizing the raw materials in the step (1) and cooling to room temperature;
(3) crushing the powder obtained in the step (2) and sieving the powder;
(4) and (4) filling the sieved medicinal powder in the step (3) into capsules.
3. The method for preparing a memory-enhancing medicament according to claim 2, wherein the method comprises the following steps: the heating and drying temperature in the step (2) is within the range of 100-150 ℃.
4. The method for preparing a memory-enhancing medicine according to claim 2, wherein the mesh number of the sieve used in the step (3) is 200 meshes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010342326.8A CN111388579A (en) | 2020-04-27 | 2020-04-27 | Medicine for enhancing memory |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010342326.8A CN111388579A (en) | 2020-04-27 | 2020-04-27 | Medicine for enhancing memory |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111388579A true CN111388579A (en) | 2020-07-10 |
Family
ID=71412508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010342326.8A Pending CN111388579A (en) | 2020-04-27 | 2020-04-27 | Medicine for enhancing memory |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111388579A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135350A (en) * | 1996-03-25 | 1996-11-13 | 魏国新 | Method for preparation of medicine good for memory |
| CN105535302A (en) * | 2014-10-30 | 2016-05-04 | 香港科技大学 | Pharmaceutical composition and preparation method thereof |
| CN105687564A (en) * | 2016-02-23 | 2016-06-22 | 广西梧州制药（集团）股份有限公司 | Traditional Chinese medicine composition for improving sleep and memory and preparation method of traditional Chinese medicine composition for improving sleep and memory |
-
2020
- 2020-04-27 CN CN202010342326.8A patent/CN111388579A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135350A (en) * | 1996-03-25 | 1996-11-13 | 魏国新 | Method for preparation of medicine good for memory |
| CN105535302A (en) * | 2014-10-30 | 2016-05-04 | 香港科技大学 | Pharmaceutical composition and preparation method thereof |
| CN105687564A (en) * | 2016-02-23 | 2016-06-22 | 广西梧州制药（集团）股份有限公司 | Traditional Chinese medicine composition for improving sleep and memory and preparation method of traditional Chinese medicine composition for improving sleep and memory |
Non-Patent Citations (4)
| Title |
|---|
| 吴国志: "《外婆的茶包小偏方》", 31 July 2015, 安微科学技术出版社 * |
| 周高超，等: "开心散对D-半乳糖致衰老小鼠非酶糖基化和自由基的抑制作用研究", 《时珍国医国药》 * |
| 蒲昭和: "远志菖蒲散防治早期老年性痴呆", 《老年人》 * |
| 赖晓明，等: "益脑胶囊治疗神经衰弱的临床研究 ", 《中药新药与临床药理》 * |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200710 |