CN104491318A - Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation - Google Patents
Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation Download PDFInfo
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Abstract
The invention discloses a traditional Chinese preparation used for treating asthma and a preparation method of the traditional Chinese preparation, and relates to the technical field of traditional Chinese medicine. The traditional Chinese preparation is composed of 19 types of traditional Chinese medicine including Chinese ephedra, asarum, evolvulus alsinoides, Elaeagnus conferta Roxb, pinellia ternate, tangerine peel, marsdenia tenacissima, toad skin, poria cocos, Chinese yam, Meconopsis racemosa Maxim, astragalus membranaceus, jujubes, tussilago farfara, negundo chastetree fruit, caesalpinia, siberian elm leaves, polygala tenuifolia and honey-fried licorice roots. The traditional Chinese preparation has a quite obvious curative effect on asthma, the preparation process is easy and convenient, and the preparation is high in stability, convenient to carry and take and easy to apply and popularize.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of asthma and preparation method thereof.
Technical background
Bronchial asthma (bronchial asthma, asthma) be by the various kinds of cell particularly chronic airway inflammation that participates in of mastocyte, eosinophilic granulocyte and T lymphocyte, in susceptible person, this kind of inflammation can cause the symptoms such as the panting of recurrent exerbation, tachypnea, uncomfortable in chest and (or) cough, how to occur at night and (or) morning, but symptom can be alleviated voluntarily or through treatment.About there are 100,000,000 asthmatic patients in the whole world, and asthma has become a kind of major chronic illnesses of serious threat public health, and the prevalence of China's asthma is about 1%, child Ke Da 3%, about has more than 1,000 ten thousand asthmatic patients according to the measuring and calculating whole nation.
The cause of disease of primary disease is more complicated, mostly thinks a kind of disease of multifactorial inheritance, by the double influence of inherited genetic factors and environmental factors.Research shows, its heritability of asthma is about 70% ~ 80%; Its environment motivating factor has: inhalation (inhalatio), infection, food, climate change, Nervous and Mental Factors and motion etc.
At present, the Western medicine for the treatment of asthma has: atropine, scopolamine, 654-2 and ipratropium bromide and diltiazem grass, verapamil, nifedipine etc., but it is mostly only for one or more symptoms of asthma, and the toxic and side effects of long-term taking is comparatively large, can not reach the object for the treatment of both the principal and secondary aspects of a disease.
The traditional Chinese medical science is thought, asthma is because impairment of dispersing and descending function of the lung, disorder of QI movement, for a long time Yu Huahuo, burning hot Tianjin of burning are expectorant, cause the resistance of mechanism of qi numbness, stagnantly then become the stasis of blood for a long time.In recent years, more emphasize that endo synergism makes asthma recurrent exerbation.Endogenous cause of ill is lung, spleen, the dirty virtual loss of kidney three, instability of surface, the turbid interior life of expectorant; Outer be admittedly six climate exopathogens, seven emotions, improper diet and overtiredness and with the inconsistent Cucumber of patient etc.The present invention is just according to dialectical above, and take into account multiple syndrome, meticulous compatibility forms.
Summary of the invention
The object of the invention is to provide a kind of steady quality, curative effect to treat the Chinese medicine preparation of asthma reliably, the present invention also aims to the preparation technology that this Chinese medicine preparation is provided, this technique is simple and feasible, meet oral drugs body absorption process, make final obtained Chinese medicine preparation good stability, curative effect is reliable.
The present inventor according to the traditional Chinese medical science to the dialectical understanding of asthma and self clinical practice of Chinese medicine for many years, on the basis of summing up traditional proved recipe, again compatibility medical material, and repeatedly grope adjustment in clinical practice, finally obtain one has remarkable therapeutic effect Chinese prescription to asthma; Inventor, according to the advantage of the absorption characteristics of oral formulations and Modern preparations technique, has invented simple process, has taken into account the Modern preparations technique of stability and curative effect.Chinese prescription in technical solution of the present invention is (with parts by weight): Herba Ephedrae 10-14 part, Herba Asari 8-12 part, Herba Evolvuli Alsinoides 10-14 part, elaeagnus conferta fruits 10-14 part, Rhizoma Pinelliae 8-12 part, Pericarpium Citri Reticulatae 15-18 part, Caulis Marsdeniae Tenacissimae 8-12 part, Cutis Bufonis 4-8 part, Poria 8-12 part, Rhizoma Dioscoreae 10-14 part, snow ginseng 8-12 part, Radix Astragali 15-18 part, Fructus Jujubae 8-12 part, Flos Farfarae 8-12 part, Fructus Viticis Cannabifoliae 10-14 part, Herba Bulbophylli reptantis 8-12 part, Folium ulmi pumilae 15-20 part, Radix Polygalae 8-12 part, Radix Glycyrrhizae Preparata 20-25 part.
Have 2 proportioning therapeutic effect the most remarkable in clinical practice, these 2 proportionings are respectively (with parts by weight):
1,12 parts, Herba Ephedrae, Herba Asari 10 parts, 12 parts, Herba Evolvuli Alsinoides, elaeagnus conferta fruits 12 parts, the Rhizoma Pinelliae 11 parts, Pericarpium Citri Reticulatae 16 parts, Caulis Marsdeniae Tenacissimae 10 parts, Cutis Bufonis 7 parts, 10 parts, Poria, Rhizoma Dioscoreae 12 parts, snow ginseng 10 parts, the Radix Astragali 16 parts, 10 parts, Fructus Jujubae, Flos Farfarae 10 parts, Fructus Viticis Cannabifoliae 12 parts, Herba Bulbophylli reptantis 10 parts, Folium ulmi pumilae 17 parts, Radix Polygalae 10 parts, Radix Glycyrrhizae Preparata 23 parts;
2,13 parts, Herba Ephedrae, Herba Asari 11 parts, 11 parts, Herba Evolvuli Alsinoides, elaeagnus conferta fruits 12 parts, the Rhizoma Pinelliae 10 parts, Pericarpium Citri Reticulatae 17 parts, Caulis Marsdeniae Tenacissimae 9 parts, Cutis Bufonis 6 parts, 10 parts, Poria, Rhizoma Dioscoreae 13 parts, snow ginseng 11 parts, the Radix Astragali 17 parts, 10 parts, Fructus Jujubae, Flos Farfarae 11 parts, Fructus Viticis Cannabifoliae 12 parts, Herba Bulbophylli reptantis 10 parts, Folium ulmi pumilae 18 parts, Radix Polygalae 11 parts, Radix Glycyrrhizae Preparata 24 parts.
The preparation technology of Chinese medicine preparation of the present invention is following steps:
The medical materials such as Herba Ephedrae, Herba Asari, Herba Evolvuli Alsinoides, elaeagnus conferta fruits, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Marsdeniae Tenacissimae, Cutis Bufonis, Poria, Rhizoma Dioscoreae, snow ginseng, the Radix Astragali, Fructus Jujubae, Flos Farfarae, Fructus Viticis Cannabifoliae, Herba Bulbophylli reptantis, Folium ulmi pumilae, Radix Polygalae, Radix Glycyrrhizae Preparata are taken by Chinese prescription of the present invention, pulverize respectively, mixing, add the purified water of 6-10 times of weight, backflow decocts 1-3 hour, filters; Filtering residue adds the purified water of 4-8 times of initial medical material weight, backflow decocts 1-2 hour, filter, by twice filtrate mixing, 1/4 of simmer down to original volume, obtains extracting solution, this extracting solution being concentrated into density is 1.20-1.36(70-80 DEG C of survey), be Chinese medical concrete, then, Chinese medical concrete added adjuvant and make finished product Chinese medicine preparation.
The preparation that Chinese medicine of the present invention is made, its dosage form can be: tablet, capsule, granule, powder, oral liquid, suck agent, electuary.
The character of the present invention's Chinese crude drug used and effect:
Herba Ephedrae: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.Select the dry herb stem of Ephedraceae plant plait Herba Ephedrae, epheday intermedia or ephedra equisetina.
Herba Asari: dispel the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Select the dry rhizome of aristolochiaceae plant Herba Asari.
Herba Evolvuli Alsinoides: relieving cough and asthma, clearing away heat-damp and promoting diuresis, scattered silt pain relieving.For bronchial asthma, cough, jaundice, stomachache, dyspepsia, acute enteritis, dysentery, urinary system infection, leucorrhea, traumatic injury, lumbago and skelalgia.Select Convolvulaceae Herba Evolvuli Alsinoides platymiscium Herba Evolvuli Alsinoides all herbal medicine.
Elaeagnus conferta fruits: relieving cough and asthma, astringing to arrest diarrhea.Cure mainly asthma, void is coughed, chronic bronchitis, enteritis, diarrhoea, treating swelling and pain by traumatic injury, rheumatalgia, jaundice.Also haematemesis can be controlled, spitting of blood, laryngopharynx swelling and pain, flu, infantile convulsion, the diseases such as skin ulcer tinea.Select Elaeangnaceae elaeagnus conferta fruits, with root, really, leaf is used as medicine.
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.Select the dry tuber of the aroid Rhizoma Pinelliae.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select the dry mature skin of rutaceae orange and variety thereof.
Caulis Marsdeniae Tenacissimae: relieving cough and asthma, lactogenesis diuresis, anticancer.For upper respiratory tract infection, bronchitis, bronchial asthma, galactostasis, dysuria, cancerous protuberance; Carbuncle furuncle infections is controlled in leaf external.Asclepiadaceae Marsdenia plant Caulis Marsdeniae Tenacissimae is selected to be used as medicine with rattan.
Cutis Bufonis: heat-clearing and toxic substances removing; Inducing diuresis to remove edema.Main carbuncle; Toxic swelling; Scrofula; Swollen scrofula; Infantile malnutrition abdominal distention; Chronic tracheitis.Select the dry body of Bufonidae animal Bufo siccus or Bufo melanostictus removing internal organs.
Poria is the dry sclerotia of On Polyporaceae Poria, is used as medicine and has the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Rhizoma Dioscoreae: spleen invigorating, tonifying the lung, reinforces the kidney, benefit essence.Control diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quench one's thirst, seminal emission, leukorrhagia, frequent micturition.Select the tuber of Dioscoreaceae plant Rhizoma Dioscoreae.
Snow ginseng: QI invigorating; Kidney tonifying.Main chronic diarrhea; Proctoptosis; Inappetence; Have blood in stool; Edema; Chronic cough; Asthma; Dizzy and nyctalopia.Select the root of the total shape Herba meconopsis integrifoliae of bloodroot.
The Radix Astragali: there is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.Select the dry root of leguminous plant Radix Astagali or Radix Astragali.
Fructus Jujubae: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.Select the dry mature fruit of Rhamnaceae jujube Fructus Jujubae.
Flos Farfarae: nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.Cough for new chronic cough, dyspnea and cough with excessive sputum, chronic cough hemoptysis.Select the dry flower of feverfew coltsfoot.
Fructus Viticis Cannabifoliae: Cleering damp and dissolving phlegm; Relieving cough and asthma; Regulating QI to relieve pain.Main cough and asthma; Stomachache; Have loose bowels; Dysentery; Colicky; Beriberi swelling; Leucorrhea; Nebulousurine.Select the fruit of Verbenaceae Herba Viticis Cannabifoliae.
Herba Bulbophylli reptantis: nourishing the lung to arrest cough; Nourishing the stomach to promote the production of body fluid; Reunion of fractured tendons and bones.Main cough spitting of blood; Chronic pharyngalgia; Chronic gastritis; Traumatic injury; Fracture.Orchid is selected to lie prostrate the herb of raw Bulbophyllum.
Folium ulmi pumilae: clearing away heat and promoting diuresis; Calm the nerves; Expelling phlegm for arresting cough.Main edema; Dysuria; Stranguria caused by urinary stone; Turbid urine; Insomnia; Summer-heat is stranded vexed; Abundant expectoration is coughed; Wine (looking into skin) nose.Select the leaf of Ulmaceae elm.
Radix Polygalae: bitter in the mouth, pungent, warm in nature; GUIXIN, kidney, lung meridian; To calm the nerves Fructus Alpiniae Oxyphyllae, eliminate the phlegm, detumescence.This product is the dry root of milk wort Radix Polygalae or ovum leaf Radix Polygalae.
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.Selecting the Preparation process product of Radix Glycyrrhizae, is similar round or oval section, and the brown or taupe brown of surface red, micro-glossy, tangent plane is yellow to buff, and cambium ring is obvious, ray irradiation shape.Matter is slightly glutinous.Tool burnt odor gas, taste is sweet.
Chinese medicine of the present invention is with relieving cough and asthma on medical material is selected, and drying dampness to eliminate phlegm is main, has invigorating the spleen and replenishing QI concurrently, and effect of nourishing blood to tranquillize the mind promotes drug effect after ladies and gentlemen's drug matching, reaches the object for the treatment of asthma; Compared with prior art, Chinese medicine preparation of the present invention have therapeutic effect good, have no side effect, the significantly technical advantage such as good, the premunition enhancing of patient body conditioning, clinical trial result in concrete visible embodiment.
Detailed description of the invention
Embodiment 1,
By Chinese prescription actual production Chinese medicine capsules of the present invention, capsule numbering A, B are 2 preferred version proportioning preparations, and capsule numbering C, D are that prescription is minimum, maximum magnitude proportioning preparation, and often kind of capsule proportioning raw materials is as shown in table 1.
Table 1 capsule proportioning raw materials table (unit: kg)
The medical materials such as Herba Ephedrae, Herba Asari, Herba Evolvuli Alsinoides, elaeagnus conferta fruits, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Marsdeniae Tenacissimae, Cutis Bufonis, Poria, Rhizoma Dioscoreae, snow ginseng, the Radix Astragali, Fructus Jujubae, Flos Farfarae, Fructus Viticis Cannabifoliae, Herba Bulbophylli reptantis, Folium ulmi pumilae, Radix Polygalae, Radix Glycyrrhizae Preparata are taken by table 1 Chinese prescription, pulverize respectively, mixing, add the purified water of 8 times of weight, backflow decoction 2 hours, filters; Filtering residue adds the purified water of 6 times of initial medical material weight, backflow decoction 1.5 hours, filters, by twice filtrate mixing, 1/4 of simmer down to original volume, obtain extracting solution, this extracting solution being concentrated into density is 1.20-1.36(75 DEG C of survey), be Chinese medical concrete, Chinese medical concrete is dried and pulverizes, add adjuvant and make capsule, specification is 0.2g/ grain, amounts to crude drug content and is about 1g/ grain.
The animal toxicity test of embodiment 2, Chinese medicine capsules of the present invention
(1) test drug: Chinese medicine capsules obtained by the embodiment of the present invention 1, abolishes capsule shells, medicated powder is added purified water and is modulated into scattered paste shape, for subsequent use.
Test animal used: regular grade NIH mice, body weight 21g ± 6g, male and female half and half, female mice is all without pregnant; SD rat, original body mass 218 ± 9g, male and female half and half, female rats is all without pregnant.
(2) acute toxicity test
Application mice carries out acute toxicity testing and shows: mouse stomach Chinese medicine magma of the present invention, under 714.6g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none dead mouse, and overall health of patients, diet, take the photograph water, urine and body weight increase all normal.Experimental result shows: the maximum dosage-feeding of mouse stomach Chinese medicine oral liquid of the present invention is 714.6g crude drug/kg/d(LD
50> 714.6g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.20g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 3573 times of clinical patient.Point out this medicine acute toxicity extremely low, clinical drug safety.
(3) long term toxicity test
Select SD rat, give the Chinese medicine oral liquid of the present invention of Three doses: 36.0g crude drug/kg, 12.0g crude drug/kg, 4.0g crude drug/kg(per weight dosage is by 20 times of calculating of clinical application amount, and clinical application amount is according to Pharmacopoeia of the People's Republic of China version in 2010).Every day gavage once, continuous 90 days, after last administration 24 hours respectively group live and kill 1/2 animal (male and female half and half), all the other 1/2 animals continue that observations are alive after 2 weeks kills.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal; Within after administration 90 days, within 2 weeks, carry out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.
Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test: Chinese medicine preparation of the present invention has no significant effect rat in high, medium and low three dosage (36.0g crude drug/kg, 12.0g crude drug/kg, 4.0g crude drug/kg) administration in continuous 90 days, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention very high.
The clinical effectiveness test of embodiment 3 Chinese medicinal capsule of the present invention
1, the source of experimenter and grouping
All experimenters all from certain the People's Hospital of city, in the asthmatic patient that year October in May, 2011 to 2013 accepts for medical treatment, therefrom filter out be applicable to test patient 165 example, wherein, man 100 example, age 49-76 year, female 65 example, age 53-75 year.All experimenters are divided into 5 groups, are numbered matched group, A group, B group, C group, D group respectively.
2, test drug
(1) compound methoxyphenamine capsules, the accurate word H20033669 of traditional Chinese medicines, the one or three is total to pharmaceutical Co. Ltd;
(2) capsule obtained by the embodiment of the present invention 1, is numbered A, B, C, D.
3, test method
Matched group takes compound methoxyphenamine capsules, every day 3 times, each 2.A-D group takes the capsule of the made numbering A-D of embodiment 1 respectively, every day 3 times, each 4 (amount to crude drug and be about 4g).Within 4 weeks, be a course for the treatment of, continuously 3 courses for the treatment of of treatment, in therapeutic process, conscientious record patient take medicine after sensation, health.
4, judgment criteria
Cure: the symptoms of asthma such as the panting of recurrent exerbation, tachypnea, uncomfortable in chest and (or) cough disappear completely, and patient recovers normal completely;
Effective: symptoms of asthma is even generation for the panting of recurrent exerbation, tachypnea, uncomfortable in chest and (or) cough etc., but be improved significantly, patient needs continual cure;
Invalid: the symptoms of asthma such as the panting of recurrent exerbation, tachypnea, uncomfortable in chest and (or) cough does not obtain any improvement, even more serious.
5, therapeutic outcome statistical analysis
After test all terminates, result of the test statistical analysis is in table 2.
Table 2 result of the test statistical analysis table
6, conclusion (of pressure testing)
As can be seen from above result of the test, the therapeutic effect of Chinese medicinal capsule of the present invention is obviously better than contrasting medicine, and average cure rate (23.5%) is 2.5 times of matched group, and average total effective rate (93.2%) is higher than matched group by 30%, and patient has no adverse reaction after taking.Therefore, Chinese medicine of the present invention particularly embodiment A group and B group prescription, relative to prior art, has significant technical advantage, has shown good technique effect.
Claims (5)
1. treat a Chinese medicine preparation for asthma, it is characterized in that being prepared from by the raw material of following weight portion: Herba Ephedrae 10-14 part, Herba Asari 8-12 part, Herba Evolvuli Alsinoides 10-14 part, elaeagnus conferta fruits 10-14 part, Rhizoma Pinelliae 8-12 part, Pericarpium Citri Reticulatae 15-18 part, Caulis Marsdeniae Tenacissimae 8-12 part, Cutis Bufonis 4-8 part, Poria 8-12 part, Rhizoma Dioscoreae 10-14 part, snow ginseng 8-12 part, Radix Astragali 15-18 part, Fructus Jujubae 8-12 part, Flos Farfarae 8-12 part, Fructus Viticis Cannabifoliae 10-14 part, Herba Bulbophylli reptantis 8-12 part, Folium ulmi pumilae 15-20 part, Radix Polygalae 8-12 part, Radix Glycyrrhizae Preparata 20-25 part.
2. treat the Chinese medicine preparation of asthma as claimed in claim 1, it is characterized in that being prepared from by the raw material of following weight portion: 12 parts, Herba Ephedrae, Herba Asari 10 parts, 12 parts, Herba Evolvuli Alsinoides, elaeagnus conferta fruits 12 parts, the Rhizoma Pinelliae 11 parts, Pericarpium Citri Reticulatae 16 parts, Caulis Marsdeniae Tenacissimae 10 parts, Cutis Bufonis 7 parts, 10 parts, Poria, Rhizoma Dioscoreae 12 parts, snow ginseng 10 parts, the Radix Astragali 16 parts, 10 parts, Fructus Jujubae, Flos Farfarae 10 parts, Fructus Viticis Cannabifoliae 12 parts, Herba Bulbophylli reptantis 10 parts, Folium ulmi pumilae 17 parts, Radix Polygalae 10 parts, Radix Glycyrrhizae Preparata 23 parts.
3. treat the Chinese medicine preparation of asthma as claimed in claim 1, it is characterized in that being prepared from by the raw material of following weight portion: 13 parts, Herba Ephedrae, Herba Asari 11 parts, 11 parts, Herba Evolvuli Alsinoides, elaeagnus conferta fruits 12 parts, the Rhizoma Pinelliae 10 parts, Pericarpium Citri Reticulatae 17 parts, Caulis Marsdeniae Tenacissimae 9 parts, Cutis Bufonis 6 parts, 10 parts, Poria, Rhizoma Dioscoreae 13 parts, snow ginseng 11 parts, the Radix Astragali 17 parts, 10 parts, Fructus Jujubae, Flos Farfarae 11 parts, Fructus Viticis Cannabifoliae 12 parts, Herba Bulbophylli reptantis 10 parts, Folium ulmi pumilae 18 parts, Radix Polygalae 11 parts, Radix Glycyrrhizae Preparata 24 parts.
4. one kind prepare as arbitrary in claim 1-3 as described in the method for Chinese medicine preparation for the treatment of asthma, it is characterized in that comprising following processing step: take Herba Ephedrae, Herba Asari, Herba Evolvuli Alsinoides, elaeagnus conferta fruits, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Marsdeniae Tenacissimae, Cutis Bufonis, Poria, Rhizoma Dioscoreae, snow ginseng, the Radix Astragali, Fructus Jujubae, Flos Farfarae, Fructus Viticis Cannabifoliae, Herba Bulbophylli reptantis, Folium ulmi pumilae, Radix Polygalae, Radix Glycyrrhizae Preparata by weight, pulverize respectively, mixing, add the purified water of 6-10 times of weight, backflow decocts 1-3 hour, filters; Filtering residue adds the purified water of 4-8 times of initial medical material weight, backflow decocts 1-2 hour, filter, by twice filtrate mixing, 1/4 of simmer down to original volume, obtains extracting solution, this extracting solution being concentrated into 70-80 DEG C of survey density is 1.20-1.36, be Chinese medical concrete, then, Chinese medical concrete added adjuvant and make finished product Chinese medicine preparation.
5. the Chinese medicine preparation for the treatment of asthma as described in as arbitrary in claim 1-3, is characterized in that: described Chinese medicine preparation is tablet, capsule, granule, powder, oral liquid, suck agent or electuary.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105561010A (en) * | 2016-02-19 | 2016-05-11 | 覃淑兰 | Chinese herbal preparation for treating asthma and preparing method thereof |
| CN108721306A (en) * | 2018-07-10 | 2018-11-02 | 云南中医学院 | Application of the Arenobufagin in preventing/treating asthmatic medicament |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647979A (en) * | 2009-09-14 | 2010-02-17 | 胡慧梅 | Traditional Chinese medicine for treating bronchial asthma |
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2015
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647979A (en) * | 2009-09-14 | 2010-02-17 | 胡慧梅 | Traditional Chinese medicine for treating bronchial asthma |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105561010A (en) * | 2016-02-19 | 2016-05-11 | 覃淑兰 | Chinese herbal preparation for treating asthma and preparing method thereof |
| CN108721306A (en) * | 2018-07-10 | 2018-11-02 | 云南中医学院 | Application of the Arenobufagin in preventing/treating asthmatic medicament |
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Application publication date: 20150408 |