CN105561010A - Chinese herbal preparation for treating asthma and preparing method thereof - Google Patents
Chinese herbal preparation for treating asthma and preparing method thereof Download PDFInfo
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- CN105561010A CN105561010A CN201610093592.5A CN201610093592A CN105561010A CN 105561010 A CN105561010 A CN 105561010A CN 201610093592 A CN201610093592 A CN 201610093592A CN 105561010 A CN105561010 A CN 105561010A
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Abstract
The invention relates to a Chinese herbal preparation for treating asthma and a preparing method thereof and belongs to the technical field of medicine. The Chinese herbal preparation is prepared from, by weight, 9-15 parts of herb of black medick, 10-15 parts of rock cotoneaster twig and leaf or root, 15-20 parts of amur foxtail, 6-9 parts of Texas sage herb, 6-12 parts of fructus canarii, 15-20 parts of paulownia fruit, 6-15 parts of axle algae, 2-8 parts of herba ephedra, 15-20 parts of cymbidium root, 5-10 parts of perilla stem, 9-15 parts of argyreia acuta lour, 5-10 parts of cordyceps sinensis, 3-9 parts of common perilla fruit, 15-20 parts of philippine flemingia root, 18-24 parts of luffa stem and 2-7 parts of agilawood. The Chinese herbal preparation can clear heat and promote diuresis, moisten lung and relieve sore-throat, eliminate phlegm and stop cough, calm the adverse-rising energy and relieve asthma, dispel wind and remove dampness, tonify spleen and kidney and the like, and when the Chinese herbal preparation is used for treating asthma, the treatment effect is remarkable, relapse does not occur easily after healing, no toxic or side effect is caused, and safety performance is high.
Description
[technical field]
The present invention relates to medical art, especially a kind of Chinese medicine preparation for the treatment of asthma and preparation method thereof.
[technical background]
Asthma is a kind of commonly encountered diseases, frequently-occurring disease, by the various kinds of cell particularly chronic airway inflammation that participates in of mastocyte, eosinophilic granulocyte and T lymphocyte, in susceptible person, this kind of inflammation can cause panting of recurrent exerbation, the symptoms such as tachypnea, uncomfortable in chest and (or) cough, small number of patients may take also chest pain as main manifestations.In the recent decade, the national asthma prevalence such as the U.S., Britain, Australia, New Zealand and mortality rate on the rise, about there are 100,000,000 asthmatic patients in the whole world, has become a kind of major chronic illnesses of serious threat public health.
The pathogenesis of asthma comprises: allergy, chronic airway inflammation, airway hyperreactivity, air flue neuroregulation are not normal, genetic mechanism, respiratory virus infection, neuronal signals transduction machine-processed and airway remodeling and interaction etc. thereof.Acute attack stage, chronic sustained phase and clinical relieving period can be divided into according to clinical manifestation asthma.Asthma in acute attack refer to pant, tachypnea, cough, the symptom such as uncomfortable in chest occur suddenly, or original symptom sharp deterioration, often have dyspnea, be reduced to its feature with expiratory gas flow, often because contact allergen, stimulus object or respiratory tract infection are brought out; The chronic sustained phase refers to weekly equal different frequency and (or) occurs symptom (pant, out of breath, uncomfortable in chest, cough etc.) to some extent; Clinical relieving period means and to disappear through treatment or untreated symptom, sign, and pulmonary function returns to level before acute attack, and maintains more than 3 months.If asthmatic patient occurs that serious acute shows effect, may be fatal when giving treatment to not in time.Control not good asthmatic patient all can make a difference to routine work and daily life, can cause delaying work, learn by mistake, cause activity, limitation of movement, quality of life is declined, and bring burden economically and the life generation negative effect to household.And asthma recurrent exerbation also may cause the complication such as chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, respiratory failure.
At present, the treatment of asthma adopts Chinese and Western combination more, its medicine many employings aminophylline, ephedrine, diphenhydramine and antibiotics etc., though these medicines can play mitigation for the moment, but great majority all can not be treated for the pathogenic factor of asthma, cure the symptoms, not the disease, easily recur after drug withdrawal, and some medicine has larger side effect, can not long-term taking; Conventional Chinese patent medicine capsule of antipyretics for lung, Bulbus Fritillariae Cirrhosae sheet etc., side effect is little, but slow curative effect, the course for the treatment of is long, and actual therapeutic effect is not fairly obvious.Therefore treat in the urgent need to a kind of the medicine that the asthma time limit is short, curative effect is high, rate is low repeatedly at present.
[summary of the invention]
For problem set forth above, the invention provides a kind of Chinese medicine preparation for the treatment of asthma, this Chinese medicine preparation is used for the treatment of asthma Be very effective, short treating period, and curative effect is high, not easily recurs after healing, and has no side effect, and takes safety.
In order to realize above-mentioned object, the technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 9-15 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 10-15 part, amur foxtail 15-20 part, Zhu's lip 6-9 part, Fructus Canarii 6-12 part, Fructus Paulowniae 15-20 part, Chara fragilis Desv. 6-15 part, Herba Ephedrae 2-8 part, orchid root 15-20 part, Caulis Perillae 5-10 part, Cortex Hibisci 9-15 part, Cordyceps 5-10 part, Fructus Perillae Frutescentis 3-9 part, Radix Flemingiae Philippinensis 15-20 part, Ramulus Luffae 18-24 part, Lignum Aquilariae Resinatum 2-7 part.
Further, described Chinese medicine preparation comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 12-14 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12-14 part, amur foxtail 17-19 part, Zhu's lip 7-8 part, Fructus Canarii 8-10 part, Fructus Paulowniae 17-19 part, Chara fragilis Desv. 8-14 part, Herba Ephedrae 4-6 part, orchid root 16-18 part, Caulis Perillae 7-9 part, Cortex Hibisci 10-14 part, Cordyceps 7-9 part, Fructus Perillae Frutescentis 5-7 part, Radix Flemingiae Philippinensis 16-18 part, Ramulus Luffae 20-22 part, Lignum Aquilariae Resinatum 4-6 part.
Further, described Chinese medicine preparation comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 13 parts, amur foxtail 18 parts, 7 parts, Zhu's lip, Fructus Canarii 9 parts, Fructus Paulowniae 18 parts, Chara fragilis Desv. 12 parts, 5 parts, Herba Ephedrae, orchid root 17 parts, Caulis Perillae 8 parts, Cortex Hibisci 12 parts, Cordyceps 8 parts, Fructus Perillae Frutescentis 6 parts, Radix Flemingiae Philippinensis 17 parts, Ramulus Luffae 21 parts, Lignum Aquilariae Resinatum 5 parts.
Further, described Chinese medicine preparation is decoction, granule, capsule, tablet or pill.
Further, the preparation method of described Chinese medicine preparation comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add raw material gross weight 6-8 water doubly, soak 2-3h, after intense fire boils, turn slow fire boiling 40-60min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add material medicine gross weight 3-5 water doubly, turn slow fire boiling 20-40min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, obtain residing Chinese medicine decoction; Or gained Chinese medicine decoction is carried out concentrating again, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make granule, capsule, tablet or pill.
Instructions of taking: each serving being the Chinese medicine preparation of 1-2g with effective dose, daily 3 times, early, middle and late half an hour after meal decoction being taken warmly, within 10 days, be a course for the treatment of, period in a medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.
Chinese medicine details of the present invention is as follows:
Herba Medicaginis Lupulinae: be the herb of leguminous plant shamrock.Summer excavates herb, and using fresh herb or chopping are dried.It is sweet puckery, and property is put down.Return lung, liver, gallbladder, kidney channel.There is effect of clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral, relieving cough and asthma, removing pathogenic heat from blood and toxic substance from the body.Main jaundice due to damp-heat, pyretic stranguria, jaundice due to damp-heat, pyretic stranguria, stranguria caused by urinary stone, rheumatic arthralgia, cough with asthma, hemorrhoidal bleeding, finger furuncle, venom.
Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis): be branch and leaf or the root of rosaceous plant Cotoneaster horizontalis.Sour in the mouth, puckery, cool in nature.Return lung, Liver Channel.There is effect of clearing away heat-damp and promoting diuresis, preventing phlegm from forming and stopping coughing, hemostasis and pain-relieving.Main dysentery, has loose bowels, stomachache, and cough is spitted blood, dysmenorrhea, leucorrhea.
Amur foxtail: be the herb of grass amur foxtail.Lightly seasoned, cool in nature.There is effect of clearing away heat-damp and promoting diuresis, antidiarrheal, removing toxic substances.Main edema, chickenpox, icterohepatitis, venom, infantile diarrhea is controlled in external, dyspepsia.
Zhu's lip: be the herb of labiate Zhu lip.Acrid in the mouth, micro-hardship, puckery, cool in nature.Return liver, spleen channel.There is effect of cooling blood for hemostasis, clearing away heat-damp and promoting diuresis.Main metrorrhagia, high heat, stomachache is uncomfortable.
Fructus Canarii: be the fruit of olive subject plant Fructus Canarii albi.Sweet in the mouth, acid, property is put down.Attach to the lung and stomach meridians.There is lung heat clearing, sore-throat relieving, promote the production of body fluid, effect of removing toxic substances.Control laryngopharynx swelling and pain, excessive thirst, cough is spitted blood, bacillary dysentery, epilepsy, separates tetrodotoxin, TTX and alcoholism." detailed outline ": control throat pain, chews pharynx juice, can separate all fish Trionyx sinensis Wiegmann poison." the southern regions of the Yunnan Province book on Chinese herbal medicine ": control on all larynx fire scorching, epidemic infection with swollen head disease.Can damp and hot, spring-warm syndrome be separated, promoting the production of body fluid to quench thirst, sharp expectorant, separate ichthyotoxin, wine, stagnate." book on Chinese herbal medicine is new again ": suppressing the hyperactive liver whets the appetite, and lung moistening YIN nourishing, expectorant is regulated the flow of vital energy, and cough-relieving is coughed, and controls haematemesis.
Fructus Paulowniae: be the fruit of goatweed Paulownia or royal paulownia.Bitter in the mouth, cold nature.Have reduce phlegm, cough-relieving, the effect of relievining asthma.Main chronic bronchitis, cough is coughed up phlegm.
Chara fragilis Desv.: be the frond of the crisp charophyta of Characeae plant.Salty in the mouth, pungent, property is put down.Return lung meridian.Have eliminate the phlegm, cough-relieving, the effect of relievining asthma.Main cough, abundant expectoration, uncomfortable in chest.
Herba Ephedrae: be the herb stem of Ephedraceae plant plait Herba Ephedrae, ephedra equisetina or epheday intermedia.Acrid in the mouth, micro-hardship, warm in nature.Return lung, urinary bladder channel.There is diaphoresis, relieving asthma, effect of diuretic.The cold table that cures the wound is real, and fever with chills is lossless, headache nasal obstruction, arthralgia, cough and asthma, edema due to wind pathogen edema, dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella pruritus." the southern regions of the Yunnan Province book on Chinese herbal medicine ": control that stuffy nose is obstructed, good and foul smells not to be heard, lung cold cough." medicinal herbs among the people of science ": control asthma, hay fever, pertussis, tracheal branches is scorching.
Orchid root: be the root of orchid sword-leaved cymbidium, orchid, Cymbidium Kanran Mak. or platform orchid.Acrid in the mouth, property is put down.There is nourishing the lung to arrest cough, clearing away heat-damp and promoting diuresis, regulate the flow of vital energy, effect of promoting blood circulation and hemostasis, removing toxic substances parasite killing.Main hemoptysis of pulmonary tuberculosis, pertussis, acute gastroenteritis, pyretic stranguria, leukorrhagia, nebulousurine, menoxenia, metrorrhagia, has blood in stool, traumatic injury, furuncle toxic swelling, hemorrhoid, and ascarid is suffered from abdominal pain, lyssodexis.
Caulis Perillae: be the stem of labiate wrinkle Folium Perillae, sharp Folium Perillae etc.Acrid-sweet flavor, slightly warm in nature.Enter spleen, stomach, lung meridian.Have regulate the flow of vital energy, Shu Yu, pain relieving, antiabortive effect.Control the stagnation of QI, dyspepsia, chest and diaphragm painful abdominal mass is vexed, epigastric pain, and nausea is got along well." must join book on Chinese herbal medicine ": soothing the liver, sharp lung, regulates the flow of vital energy, and blood, resolving depression, and pain relieving is coughed surely, antiabortive.
Cortex Hibisci: be the stem and leaf of convolvulaceous plant Caulis et Folium Argyreia eacutae.Bitter in the mouth is pungent, cool in nature.There is effect of preventing phlegm from forming and stopping coughing, regulating blood circulation to dispel wind pathogen.Control heat syndrome cough, phlegm dyspnea, spit blood, metrorrhagia, leucorrhea, traumatic injury, rheumatalgia, sore." register planted by Guangxi medicine ": expectorant, lung moistening, cough-relieving, hemostasis.Control pulmonary tuberculosis, acute mastitis, burn due to hot liquid or fire." mountain of papers Chinese herbal medicine ": relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness, relieving cough and resolving phlegm, regulating menstruation, hemostasis.Control traumatic injury, rheumatalgia, acute/chronic bronchitis.
Cordyceps: be the complex of the larva body (sclerotium) of the Stroma and host's Hepialidae insecticide Hepialus etc. thereof of section ergot fungus cordyceps sinensis bacterium.Sweet in the mouth, warm in nature.Return lung, kidney channel.There is effect of tonifying deficiency, invigorating the lung and the kidney, relieving cough and resolving phlegm.Control phlegm retention to breathe heavily and cough, dyspnea due to deficiency, consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, and prolonged deficiency is multiple after being ill." Bencao Congxin ": protect lung kidney tonifying, hemostasis and phlegm, chronic cough." modern Practical Chinese medicinal ": be applicable to the chronic cough asthma that pulmonary tuberculosis, old man are weak, haematemesis, night sweat, spontaneous perspiration; Weak for anemia again, impotence and seminal emission, old man's fear of cold, the cards such as the many lacrimations of tears." Yunnan Chinese herbal medicine ": tonifying the lung, invigorating kidney-YANG.Control expectorant to breath with cough.
Fructus Perillae Frutescentis: be the fruit of dicotyledon medicine labiate common perilla.Acrid in the mouth, property is put down.Return lung, stomach, large intestine channel.There is effect of expectorant, the therapeutic method to keep the adverse QI flowing downwards, lung moistening, wide intestinal.For cough with dyspnea, phlegm dyspnea, stagnation of QI constipation.
Radix Flemingiae Philippinensis: be the dry root of leguminous plant Flemingia philippinensis.Wei Gan ﹑ puckery, property is put down.Return lung, kidney, urinary bladder channel.There is effect of expelling wind and removing dampness, relaxing muscles and tendons bone strengthening, moistening and cleaning throat of astringing the lung.For lumbar muscle strain, hemiplegia flaccidity syndrome and arthralgia syndrome, rheumatalgia, traumatic injury, chronic cough of deficiency lung, laryngopharynx swelling and pain.
Ramulus Luffae: be the stem of cucurbitaceous plant Fructus Luffae or Guangdong Fructus Luffae.Bitter in the mouth, acid, cold nature.Enter the heart, spleen, kidney three warp.Relaxing muscles and tendons to promote blood circulation, spleen invigorating, parasite killing, relieving cough and resolving phlegm.Control waist knee joint numb limbs and tense tendons, menoxenia, edema; Tooth reveals, nasal sinusitis, gingival atrophy.
Lignum Aquilariae Resinatum: be the timber containing resin of Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum or Lignum Aquilariae Resinatum.Acrid in the mouth is bitter, warm in nature.Enter kidney, spleen, stomach warp.There is effect of promoting the circulation of QI to relieve pain, warming spleen and stomach for dispelling cold, lowering the adverse QI to relieve asthma.For the breast abdomen stagnation of QI, feeling of distension and oppression is had a pain, the limbs with coldness, umbilical part pain, vomiting singultus, QI rising in reverse order phlegm dyspnea." detailed outline ": control heat in the upper and cold in the lower, QI rising in reverse order is panted, and asthenia of the large intestine closes, urine qi stranguria, man's cold sperm." medical center bun is wanted ": hard kidney, mend the gate of vitality, warming middle-JIAO, dry spleen are wet, and removing pathogen in the heart, lowering the adverse flow of QI, all uncomfortable gas all can adjust it.And control keep silent mouthful fulminant dysentery and evil cold wind arthralgia due to cold." book on Chinese herbal medicine is new again ": treating the liver is strongly fragrant, falls irritability, and taste, disappear dampness, and diuretic is had one's ideas straightened out.
The invention provides a kind of Chinese medicine preparation for the treatment of asthma and preparation method thereof, compared with prior art, there is following beneficial effect:
The Chinese medicine preparation for the treatment of asthma provided by the present invention makes up a prescription according to the curative mechanism of asthma, with Herba Medicaginis Lupulinae, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis), amur foxtail, Zhu's lip, Fructus Canarii, Fructus Paulowniae, Chara fragilis Desv., Herba Ephedrae, orchid root, Caulis Perillae, Cortex Hibisci, Cordyceps, Fructus Perillae Frutescentis, Radix Flemingiae Philippinensis, Ramulus Luffae, Lignum Aquilariae Resinatum for primary raw material, wherein Herba Medicaginis Lupulinae, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis), amur foxtail, Zhu's lip can clearing away heat-damp and promoting diuresis, removing toxic substances, relieving cough and asthma; Fructus Canarii has lung heat clearing, sore-throat relieving, the effect of promoting the production of body fluid, detoxifying; Fructus Paulowniae, Chara fragilis Desv., Herba Ephedrae can reduce phlegm, cough-relieving, relieving asthma; Orchid root, Caulis Perillae are regulated the flow of vital energy Shu Yu; Cortex Hibisci, Cordyceps, Fructus Perillae Frutescentis lung moistening expectorant; Radix Flemingiae Philippinensis expelling wind and removing dampness, moistening and cleaning throat of astringing the lung; Ramulus Luffae, Lignum Aquilariae Resinatum can kidney and spleen invigorating, warming spleen and stomach for dispelling cold, lowering the adverse QI to relieve asthmas.All medicine compatibilities above, bring out the best in each other, play the effects such as clearing away heat-damp and promoting diuresis, moistening lung and nourishing throat, preventing phlegm from forming and stopping coughing, lowering the adverse QI to relieve asthma, expelling wind and removing dampness, strengthening spleen, tonifying kidney altogether, physical function can be regulated on the whole, fundamentally treat asthma, evident in efficacy, short treating period, curative effect is high, cure after not easily recur, and the property of medicine is gentle, have no side effect, safe and reliable.
[detailed description of the invention]
The following examples can help those skilled in the art more fully to understand the present invention, but cannot limit the present invention by any way.
Embodiment 1
Treat a Chinese medicine decoction for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 9 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 10 parts, amur foxtail 15 parts, 6 parts, Zhu's lip, Fructus Canarii 6 parts, Fructus Paulowniae 15 parts, Chara fragilis Desv. 6 parts, 2 parts, Herba Ephedrae, orchid root 15 parts, Caulis Perillae 5 parts, Cortex Hibisci 9 parts, Cordyceps 5 parts, Fructus Perillae Frutescentis 3 parts, Radix Flemingiae Philippinensis 15 parts, Ramulus Luffae 18 parts, Lignum Aquilariae Resinatum 2 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add the water of raw material gross weight 6 times, soak 2h, after intense fire boils, turn slow fire boiling 40min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add the water of material medicine gross weight 3 times, turn slow fire boiling 20min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, get product Chinese medicine decoction;
Embodiment 2
Treat a Chinese medicine granules for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 12 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12 parts, amur foxtail 17 parts, 7 parts, Zhu's lip, Fructus Canarii 8 parts, Fructus Paulowniae 17 parts, Chara fragilis Desv. 8 parts, 4 parts, Herba Ephedrae, orchid root 16 parts, Caulis Perillae 7 parts, Cortex Hibisci 10 parts, Cordyceps 7 parts, Fructus Perillae Frutescentis 5 parts, Radix Flemingiae Philippinensis 16 parts, Ramulus Luffae 20 parts, Lignum Aquilariae Resinatum 4 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add the water of raw material gross weight 6 times, soak 2h, after intense fire boils, turn slow fire boiling 50min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add the water of material medicine gross weight 3 times, turn slow fire boiling 30min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, fully mix, obtain admixing medical solutions; Again admixing medical solutions is carried out concentrating, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make Chinese medicine granules according to the manufacture method making conventional granulates agent.
Embodiment 3
Treat a Chinese medicine capsules for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 13 parts, amur foxtail 18 parts, 7 parts, Zhu's lip, Fructus Canarii 9 parts, Fructus Paulowniae 18 parts, Chara fragilis Desv. 12 parts, 5 parts, Herba Ephedrae, orchid root 17 parts, Caulis Perillae 8 parts, Cortex Hibisci 12 parts, Cordyceps 8 parts, Fructus Perillae Frutescentis 6 parts, Radix Flemingiae Philippinensis 17 parts, Ramulus Luffae 21 parts, Lignum Aquilariae Resinatum 5 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add the water of raw material gross weight 7 times, soak 2.5h, after intense fire boils, turn slow fire boiling 50min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add the water of material medicine gross weight 4 times, turn slow fire boiling 30min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, fully mix, obtain admixing medical solutions; Again admixing medical solutions is carried out concentrating, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make Chinese medicine capsules according to the manufacture method making conventional capsule.
Embodiment 4
Treat a Chinese medicinal tablet for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 14 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 14 parts, amur foxtail 19 parts, 8 parts, Zhu's lip, Fructus Canarii 10 parts, Fructus Paulowniae 19 parts, Chara fragilis Desv. 14 parts, 6 parts, Herba Ephedrae, orchid root 18 parts, Caulis Perillae 9 parts, Cortex Hibisci 14 parts, Cordyceps 9 parts, Fructus Perillae Frutescentis 7 parts, Radix Flemingiae Philippinensis 18 parts, Ramulus Luffae 22 parts, Lignum Aquilariae Resinatum 6 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add the water of weight 8 times in raw material, soak 3h, after intense fire boils, turn slow fire boiling 60min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add the water of material medicine gross weight 5 times, turn slow fire boiling 40min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, fully mix, obtain admixing medical solutions; Again admixing medical solutions is carried out concentrating, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make Chinese medicinal tablet according to the manufacture method making conventional tablet.
Embodiment 5
Treat a medicine pill for asthma, it comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 15 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 15 parts, amur foxtail 20 parts, 9 parts, Zhu's lip, Fructus Canarii 12 parts, Fructus Paulowniae 20 parts, Chara fragilis Desv. 15 parts, 8 parts, Herba Ephedrae, orchid root 20 parts, Caulis Perillae 10 parts, Cortex Hibisci 15 parts, Cordyceps 10 parts, Fructus Perillae Frutescentis 9 parts, Radix Flemingiae Philippinensis 20 parts, Ramulus Luffae 24 parts, Lignum Aquilariae Resinatum 7 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add the water of raw material gross weight 7 times, soak 3h, after intense fire boils, turn slow fire boiling 40min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add the water of material medicine gross weight 4 times, turn slow fire boiling 20min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, fully mix, obtain admixing medical solutions; Again admixing medical solutions is carried out concentrating, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make medicine pill according to the manufacture method making conventional pill.
Clinical observation statistics
1, the object of observation:
Select asthmatic patient 200 example made a definite diagnosis to carry out clinical observation, cardinal symptom: during seizure of disease with cough, expectoration, pant, breathe the symptoms such as suffering, uncomfortable in chest and chest pain.Be divided into treatment group and matched group at random, treatment group 100 example, wherein male 58 example, women 42 example, age 18-60 year, the shortest person of the course of disease 6 months, most elder 15 years; Matched group 100 example, wherein, male 53 example, women 47 example, age 20-65 year, the course of disease the shortest person half a year, most elder 15 years.The sex for the treatment of group and matched group two groups of cases, age, the state of an illness are basically identical, without significant difference, have comparability.
2, Therapeutic Method
Treatment group: Chinese medicine preparation of the present invention for oral administration, every day 3 times, each serving being the Chinese medicine preparation of 1-2g with effective dose, early, middle and late half an hour after meal decoction being taken warmly, it within 10 days, is a course for the treatment of, observe after taking 2-4 the course for the treatment of, period in a medicine withdraws other drug, and avoid eating anything raw or cold, pungent, stimulate food.
Matched group: the oral treatment asthmatic medicament (Singulair or terbutaline sulphate sheet etc.) bought on the market, take according to taking explanation, carry out Synchronous with treatment group, period in a medicine withdraws other drug, and avoid eating anything raw or cold, pungent, stimulate food.
4, standard is treated
Cure: symptoms of asthma, sign disappear, and follow up a case by regular visits to half a year without recidivist; Effective: symptoms of asthma obviously alleviates, and attack times reduces to some extent; Invalid: after medication, the symptoms of asthma of patient has no improvement.
5, therapeutic outcome
Treatment group and matched group clinical treatment outcome as shown in table 1:
Table 1 treatment group and matched group clinical treatment outcome
| n | Recovery from illness | Effectively | Invalid | Total effective rate (%) | |
| Treatment group | 100 | 52 | 37 | 11 | 89 |
| Matched group | 100 | 26 | 41 | 33 | 67 |
Clinical treatment outcome as can be seen from upper table 1 treatment group and matched group: treatment group 100 example, take after the present invention treats Chinese medicine preparation 2-4 course for the treatment of of asthma, cure 52 examples (accounting for sum 52%), effective 37 examples (accounting for sum 37%), invalid 11 examples, total effective rate is 89%; Matched group 100 example, takes treatment asthmatic medicament commercially available at present, synchronously carries out observing with treatment group, cures 26 examples (accounting for sum 26%), effective 41 examples (accounting for sum 41%), invalid 33 examples, and total effective rate is 67%; Visible, it is effective that Chinese medicine preparation of the present invention is used for the treatment of asthma, and cure rate is high.
Model case:
Case 1: Korea Spro so-and-so, female, 29 years old, suffer from asthma within 3 years, have a surplus, recent anemofrigid cold recurrence, rapid breathing, lies awake all night, gurgling with sputum, sound, as dragsaw, is very felt bad, and recommends to take medicine of the present invention, after the course for the treatment of through people, breathe mild, rale sound alleviates, and continues to take two courses for the treatment of, above-mentioned disease disappears, and physical recovery is normal, is consolidate curative effect, continue again a course for the treatment of of taking medicine, pay a return visit after 1 year, period has no recurrence.
Case 2: permitted so-and-so, male, 45 years old, suffer from asthma for many years, cardinal symptom: cough with asthma is out of breath, wheezing in larynx, expectoration thickness, abdominal distention, constipation, misery unbearably.Used multiple Drug therapy once, but poor effect, recurrent exerbation; Use Chinese medicine preparation of the present invention afterwards instead, take medicine 2 courses for the treatment of, patients symptomatic obviously alleviates, and continues to take 4 courses for the treatment of, and patients symptomatic disappears, and follow up a case by regular visits to 2 years, period has no recurrence.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (5)
1. treat the Chinese medicine preparation of asthma for one kind, it is characterized in that, described Chinese medicine preparation comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 9-15 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 10-15 part, amur foxtail 15-20 part, Zhu's lip 6-9 part, Fructus Canarii 6-12 part, Fructus Paulowniae 15-20 part, Chara fragilis Desv. 6-15 part, Herba Ephedrae 2-8 part, orchid root 15-20 part, Caulis Perillae 5-10 part, Cortex Hibisci 9-15 part, Cordyceps 5-10 part, Fructus Perillae Frutescentis 3-9 part, Radix Flemingiae Philippinensis 15-20 part, Ramulus Luffae 18-24 part, Lignum Aquilariae Resinatum 2-7 part.
2. the Chinese medicine preparation for the treatment of asthma as claimed in claim 1, it is characterized in that, described Chinese medicine preparation comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 12-14 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12-14 part, amur foxtail 17-19 part, Zhu's lip 7-8 part, Fructus Canarii 8-10 part, Fructus Paulowniae 17-19 part, Chara fragilis Desv. 8-14 part, Herba Ephedrae 4-6 part, orchid root 16-18 part, Caulis Perillae 7-9 part, Cortex Hibisci 10-14 part, Cordyceps 7-9 part, Fructus Perillae Frutescentis 5-7 part, Radix Flemingiae Philippinensis 16-18 part, Ramulus Luffae 20-22 part, Lignum Aquilariae Resinatum 4-6 part.
3. the Chinese medicine preparation for the treatment of asthma as claimed in claim 2, it is characterized in that, described Chinese medicine preparation comprises the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 13 parts, amur foxtail 18 parts, 7 parts, Zhu's lip, Fructus Canarii 9 parts, Fructus Paulowniae 18 parts, Chara fragilis Desv. 12 parts, 5 parts, Herba Ephedrae, orchid root 17 parts, Caulis Perillae 8 parts, Cortex Hibisci 12 parts, Cordyceps 8 parts, Fructus Perillae Frutescentis 6 parts, Radix Flemingiae Philippinensis 17 parts, Ramulus Luffae 21 parts, Lignum Aquilariae Resinatum 5 parts.
4. the Chinese medicine preparation of the treatment asthma as described in as arbitrary in claim 1-3, is characterized in that: described Chinese medicine preparation is decoction, granule, capsule, tablet or pill.
5. the preparation method of the Chinese medicine preparation for the treatment of asthma as claimed in claim 4, is characterized in that described preparation method is:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) after the raw material got cleans and dries, disconnected be broken to length and be less than 1cm, be mixed and put into pot, add raw material gross weight 6-8 water doubly, soak 2-3h, after intense fire boils, turn slow fire boiling 40-60min, filter to obtain medicinal residues I and medicinal liquid I, and in backward medicinal residues I, add material medicine gross weight 3-5 water doubly, turn slow fire boiling 20-40min after intense fire boils, filter to obtain medicinal liquid II;
3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, obtain residing Chinese medicine decoction; Or gained Chinese medicine decoction is carried out concentrating again, dry, pulverize, and then add pharmaceutically acceptable adjuvant, make granule, capsule, tablet or pill.
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| CN102133319A (en) * | 2011-03-18 | 2011-07-27 | 邴超 | Medicament for relieving asthma and cough and preparation method thereof |
| CN104491318A (en) * | 2015-01-22 | 2015-04-08 | 崔合芳 | Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation |
| CN104645003A (en) * | 2015-01-29 | 2015-05-27 | 崔银方 | Traditional Chinese medicine preparation for treating asthma and preparation method of traditional Chinese medicine preparation |
| CN105250968A (en) * | 2015-11-12 | 2016-01-20 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine preparation for treating asthma |
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| CN102133319A (en) * | 2011-03-18 | 2011-07-27 | 邴超 | Medicament for relieving asthma and cough and preparation method thereof |
| CN104491318A (en) * | 2015-01-22 | 2015-04-08 | 崔合芳 | Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation |
| CN104645003A (en) * | 2015-01-29 | 2015-05-27 | 崔银方 | Traditional Chinese medicine preparation for treating asthma and preparation method of traditional Chinese medicine preparation |
| CN105250968A (en) * | 2015-11-12 | 2016-01-20 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine preparation for treating asthma |
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