CN111388400A

CN111388400A - Composition for balancing skin oil secretion and preparation method thereof

Info

Publication number: CN111388400A
Application number: CN201811529165.2A
Authority: CN
Inventors: 祖丹
Original assignee: Guangzhou Wanbi Biotechnology Co ltd
Current assignee: Guangzhou Wanbi Biotechnology Co ltd
Priority date: 2018-12-14
Filing date: 2018-12-14
Publication date: 2020-07-10

Abstract

The invention discloses a composition for balancing skin oil secretion, which comprises the following components in percentage by weight: 0.05-2% of Chinese rose stem cell extract, 3-20% of lotus leaf extract, 3-20% of plum blossom extract, 3-20% of rosemary extract, 0.5-5% of thickening agent, 0.05-0.5% of preservative and the balance of deionized water. The composition takes the four plant components of the Chinese rose stem cell extract, the lotus leaf extract, the plum blossom extract and the rosemary extract as effective active components, and is natural, non-toxic and non-irritant. Tests show that the composition has better oil balancing effect than the current products on the market, and can fundamentally solve the problem of facial skin oil secretion disorder.

Description

Composition for balancing skin oil secretion and preparation method thereof

Technical Field

The invention relates to a skin care product, in particular to a composition for balancing skin grease secretion and a preparation method thereof.

Background

With the increasing age, the social pressure is too great, the problems of environmental pollution, computer radiation and the like become more serious, and more people are interfered by various skin problems. Sebum is oil that is produced by sebaceous gland cells inside the skin and then secreted to the skin surface. Excessive sebum secretion can lead microorganisms to rapidly proliferate in hair follicles, easily cause pore blockage, and cause the generation of acnes and inflammation; when sebum secretion is too small, various problems such as dry skin and roughness may occur. Therefore, effective regulation and repair of the sebaceous gland's lipid secretion function is the first step in establishing the skin barrier function.

Although a few products for controlling facial oil secretion are on the market at present, most of the products are made of chemical raw materials, and some people are particularly sensitive to chemicals and are easy to be allergic after use.

Disclosure of Invention

The present invention aims at overcoming the demerits of available technology, and provides one kind of composition for balancing skin oil secretion and its preparation process. The composition is prepared from active ingredients extracted from plants, is natural and non-toxic, and has a good oil balance effect.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

a composition for balancing skin oil secretion comprises the following components in percentage by weight: 0.05-2% of Chinese rose stem cell extract, 3-20% of lotus leaf extract, 3-20% of plum blossom extract, 3-20% of rosemary extract, 0.5-5% of thickening agent, 0.05-0.5% of preservative and the balance of deionized water.

As a preferable scheme of the invention, the composition comprises the following components in percentage by weight: 0.1-1% of Chinese rose stem cell extract, 10-15% of lotus leaf extract, 10-15% of plum blossom extract, 10-15% of rosemary extract, 2-4% of thickening agent, 0.1-0.3% of preservative and the balance of deionized water.

As a preferable scheme of the invention, the composition comprises the following components in percentage by weight: 0.4-0.6% of Chinese rose stem cell extract, 12-14% of lotus leaf extract, 12-14% of plum blossom extract, 11-13% of rosemary extract, 2.5-3.5% of thickening agent, 0.15-0.25% of preservative and the balance of deionized water.

As the most preferable scheme of the invention, the composition comprises the following components in percentage by weight: 0.5% of Chinese rose stem cell extract, 13% of lotus leaf extract, 13% of plum blossom extract, 12% of rosemary extract, 3% of thickening agent, 0.2% of preservative and the balance of deionized water.

The folium Nelumbinis is leaf of Nelumbo nucifera Gaertn of Nymphaeaceae. The alkaloid substances rich in the lotus leaf extract have good oil balancing function and strong bacteriostatic action on bacteria, yeast and mould.

The plum blossom is the flower bud of plum blossom (Prunus mume Sieb. et Zucc.) belonging to Rosaceae, and the plum blossom extract is rich in chlorogenic acid, rutin, hyperoside, isoquercitrin and other chemical components, has various obvious skin care effects, has obvious inhibition effect on 5 α -reductase, and has effect of reducing skin greasiness.

Rosemary (scientific name: Rosmarinus officinalis) has strong astringent effect, and Rosemary extract is rich in diterpene phenols and rosmarinic acid. Rosemary extract has effects of promoting skin blood circulation, resisting oxidation, increasing skin elasticity and luster, and delaying skin aging.

The rose flower (with the scientific name: Rosa chinensis Jacq.) is rich in phenolic substances and flavonoid substances and has strong anti-inflammatory, bactericidal and bacteriostatic effects, and the active ingredients contained in the rose stem cell extract are several times more than those in the rose flower, so that the efficacy intensity is stronger.

As a further embodiment of the present invention, the method for preparing the chinese rose stem cell extract comprises the steps of:

① obtaining Chinese rose stem cells, namely taking the tips of the new branches of Chinese rose, disinfecting the tips, peeling off xylem, culturing the tissues containing cambium, phloem, cortex and epidermis on a separation culture medium for 30 days, separating the new cambium stem cells from dedifferentiated callus, and transferring the separated cambium stem cells to a growth culture medium for culture to obtain the Chinese rose stem cells;

② freezing the dried cells of Chinese rose obtained in step ①, crushing, filtering, and concentrating the filtrate to obtain the Chinese rose dried cell extract.

As a preferred embodiment of the present invention, the thickener is sodium hyaluronate, xanthan gum or guar gum.

In a preferred embodiment of the present invention, the preservative is ethylparaben, propylparaben, or butylparaben.

The preparation method of the composition comprises the following steps:

① adding deionized water into the pot, heating to 70-80 deg.C, slowly adding thickener under low-speed stirring, and stirring;

② cooling to 50 deg.C, sequentially adding herba Rosmarini officinalis extract, folium Nelumbinis extract, flos Pruni mume extract, and flos Rosae chinensis stem cell extract, and homogenizing;

③ and cooling to 40 deg.C, adding antiseptic, and stirring to obtain the composition.

A facial mask liquid for balancing skin oil secretion is prepared from the components of the composition by the preparation method of the composition.

The invention has the beneficial effects that: the composition takes the four plant components of the Chinese rose stem cell extract, the lotus leaf extract, the plum blossom extract and the rosemary extract as effective active components, and is natural, non-toxic and non-irritant. Tests show that the composition has better oil balancing effect than the current products on the market, and can fundamentally solve the problem of facial skin oil secretion disorder.

Detailed Description

To illustrate the technical solutions of the present invention more clearly, the following embodiments are further described, but the present invention is not limited thereto, and only some embodiments of the present invention are given.

The plant extract purchase information used in the embodiments of the present invention is as follows:

name of commodity	Purchasing manufacturer	Type of goods
			Lotus leaf extract	XI ' AN YUENSUN BIOLOGICAL TECHNOLOGY Co.,Ltd.	Cosmetic grade
Plum blossom extract	Seashen biotechnologyCo., Ltd.	Cosmetic grade
			Rosemary extract	Saanenry biotechnology limited	Cosmetic grade

Example 1

The embodiment 1 provides a mask liquid for balancing skin oil secretion, which comprises the following components in percentage by weight: 0.5% of Chinese rose stem cell extract, 13% of lotus leaf extract, 13% of plum blossom extract, 12% of rosemary extract, 3% of sodium hyaluronate, 0.2% of ethylparaben and the balance of deionized water.

The preparation method of the facial mask liquid comprises the following steps:

① adding deionized water into the pan, heating to 75 deg.C, slowly adding sodium hyaluronate under low-speed stirring, and stirring;

③ and cooling to 40 deg.C, adding ethylparaben, and stirring to obtain facial mask solution.

Example 2

The embodiment 2 provides a mask liquid for balancing skin oil secretion, which comprises the following components in percentage by weight: 0.1% of Chinese rose stem cell extract, 15% of lotus leaf extract, 10% of plum blossom extract, 15% of rosemary extract, 4% of xanthan gum, 0.1% of propyl hydroxybenzoate and the balance of deionized water.

The preparation method of the facial mask liquid comprises the following steps:

① adding deionized water into the pan, heating to 70 deg.C, slowly adding xanthan gum under low-speed stirring, and stirring;

③ and cooling to 40 deg.C, adding propyl hydroxybenzoate, and stirring to obtain facial mask solution.

Example 3

The embodiment 3 provides a mask liquid for balancing skin oil secretion, which comprises the following components in percentage by weight: 1% of Chinese rose stem cell extract, 10% of lotus leaf extract, 15% of plum blossom extract, 10% of rosemary extract, 2% of guar gum, 0.3% of butylparaben and the balance of deionized water.

The preparation method of the facial mask liquid comprises the following steps:

① adding deionized water into the pan, heating to 80 deg.C, slowly adding guar gum under low-speed stirring, and stirring;

③ and cooling to 40 deg.C, adding butyl hydroxybenzoate, and stirring to obtain facial mask solution.

Example 4

The embodiment 4 provides a mask liquid for balancing skin oil secretion, which contains the following components in percentage by weight: 0.05% of Chinese rose stem cell extract, 20% of lotus leaf extract, 3% of plum blossom extract, 20% of rosemary extract, 5% of xanthan gum, 0.5% of butylparaben and the balance of deionized water.

The preparation method of the facial mask liquid comprises the following steps:

① adding deionized water into the pan, heating to 78 deg.C, slowly adding xanthan gum under low-speed stirring, and stirring;

Example 5

This example 5 provides a mask solution for balancing skin oil secretion, which contains the following components in percentage by weight: 2% of Chinese rose stem cell extract, 3% of lotus leaf extract, 20% of plum blossom extract, 3% of rosemary extract, 0.5% of sodium hyaluronate, 0.05% of oxybenzene butyl ester and the balance of deionized water.

The preparation method of the facial mask liquid comprises the following steps:

① adding deionized water into the pan, heating to 72 deg.C, slowly adding sodium hyaluronate under low-speed stirring, and stirring;

Example 6

The method for preparing a rose stem cell extract according to embodiment 1 to 5, comprising the steps of:

② freezing the dried cells of Rosa chinensis (Thunb.) nakai) obtained in step ① at-70 deg.C for 3h, thawing for 40min, breaking the cells with an ultrasonic breaker, filtering with a filter, collecting the filtrate, and concentrating the filtrate with a rotary evaporator to obtain the dried cell extract of Rosa chinensis (Thunb.) nakai).

Comparative example 1: a mask liquid lacking a chinese rose stem cell extract, compared to example 1.

Comparative example 2: a mask liquid lacking rosemary extract compared to example 1.

Comparative example 3: a facial mask solution lacking lotus leaf extract as compared to example 1.

Comparative example 4: a facial mask liquid, lacking plum blossom extract, compared to example 1.

Test of

First, irritation test

1. The test substance: the facial mask solutions of examples 1 to 5 and comparative examples 1 to 4.

2. According to the requirements of technical Specification for safety of cosmetics 2015, 45 volunteers aged 20-50 years are selected as test subjects. The mask liquids of examples 1 to 5 and comparative examples 1 to 4 were tried on 45 subjects on average in 9 groups.

3. The experimental method comprises accurately measuring 0.020m L facial mask liquid, and placing into a spot tester (area 30 mm)²Depth 1 mm), applying the spot tester with facial mask liquid on the curved side of forearm of the subject with hypoallergenic tape, applying the patch tester on the skin by pressing with palm gently, continuously applying for 24h, removing the spot tester for 30min, 24h and 48h, observing skin reaction according to the standard of Table 1, and recording the observation result.

TABLE 1

The final result is observed to be: the skin reaction degree of the subjects who try the facial mask fluids of the examples 1-5 is minus, and the rating is 0, so that the facial mask fluid is mild and has no stimulation. Most subjects who use the facial mask fluids of comparative examples 1-4 are all-skin reaction degree, and the grade is 0; the skin of 3 subjects showed slight erythema, and the rating was 1, which proved that the facial mask solutions of comparative examples 1-4 had little irritation to human skin.

Second, efficacy test for balancing skin oil secretion

1. The test substance: the facial mask solutions of examples 1-5, the facial mask solutions of comparative examples 1-4, and commercially available oil control skin care products.

2. The subject claims: the total number of the skin care products is 50, the skin care products are aged 22-40 years, oily and mixed skin does not have any history of skin diseases and skin allergy, the skin care products voluntarily participate in the test, an informed consent is signed before the test, no cosmetics can be used 2 days before the test, and no cosmetics except for the test sample can be used in the test process. After a subject washes the face with warm water, the cosmetic preparation is uniformly applied to the face once in the morning and once in the evening for 8 weeks.

3. The experimental principle is as follows: the grease test is based on the photometer principle. A special extinction adhesive tape with the thickness of 0.1mm is selected, and grease on human skin can be rapidly absorbed. The extinction adhesive tape is changed into a semitransparent state under the action of the grease, the more the grease is absorbed, the greater the light transmission amount is, the light transmission amount is measured by a photometer, and the content of the skin grease can be measured according to the change of the light transmission amount before and after the extinction adhesive tape.

4. Testing an instrument: sebumeter, a skin moisture tester CM825, manufactured by Courage + Khazaka (CK) of Germany.

5. The experimental method comprises the following steps: 50 subjects were randomized into 10 groups of 5 subjects each. The forehead, the left and right cheekbones of the face, the left and right cheeks at the intersection of the nose tip and the pupil, and the left and right sides at the intersection of the temple and the mouth corner of the subject were selected as the test areas. Group a subjects used the facial mask fluid of example 1; panel B used the facial mask solution of example 2; panel C used the facial mask solution of example 3; panel D used the facial mask solution of example 4; panel E used the facial mask solution of example 5; group F used the facial mask solution of comparative example 1; group G the facial mask solution of comparative example 2 was used; group H used the facial mask solution of comparative example 3; group I used the facial mask solution of comparative example 4; commercial products were used for group J.

The test period was 4 weeks, the subjects were smeared 1 time each morning and evening, the test area was measured 3 times by the technician before the test and 2 weeks, 4 weeks after the start of the test, respectively, using the skin oil probe and the skin moisture test probe, and the average value was taken.

The test results are shown in table 2:

TABLE 2

As can be seen from the results in table 2, the skin oil of group A, B, C, D, E showed a tendency to decrease, and become more effective after the second week of use, while the moisture content of the skin also showed a tendency to increase, indicating that: the facial mask liquid has a good oil control effect, and can adjust the oil-water balance of skin.

F. G, H, I group 1 also had less skin oil and fat, but the change was not obvious, and the increase of skin moisture content was not obvious, which indicates that the facial mask solution of the control group could adjust the oil-water balance of skin, but the effect was not obvious, further explaining: in the aspect of regulating the oil-water balance of skin, the compound of the Chinese rose stem cell extract, the lotus leaf extract, the plum blossom extract and the rosemary extract has a synergistic effect.

The skin oil secretion of the J group is not reduced or increased, and the increase of the skin water content is not obvious, which indicates that: compared with the commercially available oil-control skin care products, the facial mask liquid has better effects on balancing the secretion of skin oil and regulating the oil-water balance of the skin.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the same. Although the present invention has been described in detail with reference to the above embodiments, it should be understood by those of ordinary skill in the art that: modifications and equivalents may be made to the embodiments of the invention without departing from the spirit and scope of the invention, which is to be covered by the claims.

Claims

1. A composition for balancing skin oil secretion is characterized by comprising the following components in percentage by weight: 0.05-2% of Chinese rose stem cell extract, 3-20% of lotus leaf extract, 3-20% of plum blossom extract, 3-20% of rosemary extract, 0.5-5% of thickening agent, 0.05-0.5% of preservative and the balance of deionized water.

2. The composition of claim 1, comprising the following components in weight percent: 0.1-1% of Chinese rose stem cell extract, 10-15% of lotus leaf extract, 10-15% of plum blossom extract, 10-15% of rosemary extract, 2-4% of thickening agent, 0.1-0.3% of preservative and the balance of deionized water.

3. The composition of claim 2, comprising the following components in weight percent: 0.4-0.6% of Chinese rose stem cell extract, 12-14% of lotus leaf extract, 12-14% of plum blossom extract, 11-13% of rosemary extract, 2.5-3.5% of thickening agent, 0.15-0.25% of preservative and the balance of deionized water.

4. The composition of claim 3, comprising the following components in weight percent: 0.5% of Chinese rose stem cell extract, 13% of lotus leaf extract, 13% of plum blossom extract, 12% of rosemary extract, 3% of thickening agent, 0.2% of preservative and the balance of deionized water.

5. The composition according to any one of claims 1 to 4, wherein [ U1], comprises the steps of:

6. The composition according to any one of claims 1 to 4, wherein the thickening agent is sodium hyaluronate, xanthan gum or guar gum.

7. The composition of any one of claims 1 to 4, wherein the preservative is ethylparaben, propylparaben, or butylparaben.

8. A process for the preparation of a composition according to any one of claims 1 to 4, comprising the steps of:

① adding deionized water into the pan, heating to 70-80 deg.C, slowly adding thickener under low-speed stirring, and homogenizing;

9. A facial mask solution for balancing skin oil secretion, which is prepared from the ingredients of any one of claims 1 to 4 by the method of claim 8.