CN111386128A - 用于免疫调节的联合疗法 - Google Patents

用于免疫调节的联合疗法 Download PDF

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Publication number
CN111386128A
CN111386128A CN201880076269.4A CN201880076269A CN111386128A CN 111386128 A CN111386128 A CN 111386128A CN 201880076269 A CN201880076269 A CN 201880076269A CN 111386128 A CN111386128 A CN 111386128A
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cancer
virus
atoms
represents hydrogen
substituted
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Chinese (zh)
Inventor
波塔伊尔·戈文丹·奈尔·萨斯库马
穆拉利达拉·拉马钱德拉
R·K·拉马钱德拉
A·S·拉佐恰克
T·L·怀恩特
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Aurigene Oncology Ltd
Curis Inc
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Aurigene Discovery Technologies Ltd
Curis Inc
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Publication of CN111386128A publication Critical patent/CN111386128A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201880076269.4A 2017-11-06 2018-10-31 用于免疫调节的联合疗法 Pending CN111386128A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201741039497 2017-11-06
IN201741039497 2017-11-06
PCT/IB2018/058533 WO2019087092A1 (en) 2017-11-06 2018-10-31 Conjoint therapies for immunomodulation

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CN111386128A true CN111386128A (zh) 2020-07-07

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US (2) US11497735B2 (https=)
EP (1) EP3706798A1 (https=)
JP (2) JP7378395B2 (https=)
KR (1) KR20200084333A (https=)
CN (1) CN111386128A (https=)
AU (2) AU2018360389B2 (https=)
CA (1) CA3081675A1 (https=)
EA (1) EA202090749A1 (https=)
WO (1) WO2019087092A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991559A (zh) * 2020-09-03 2020-11-27 中山大学 受体酪氨酸激酶抑制剂在制备预防和/或治疗新型冠状病毒感染药物中的应用
CN115025097A (zh) * 2022-06-30 2022-09-09 四川大学 雷替曲塞在制备靶向chmp3基因的药物中的应用

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CN111386128A (zh) 2017-11-06 2020-07-07 奥瑞基尼探索技术有限公司 用于免疫调节的联合疗法
BR112020019083A2 (pt) 2018-03-21 2020-12-29 Five Prime Therapeutics, Inc. Anticorpos, ácido nucleico, composições, célula e métodos para preparar um anticorpo, para tratar câncer, para tratar uma doença infecciosa, para tratar uma inflamação, para a identificação de um anticorpo, para melhorar a eficácia antitumoral de um anticorpo, para melhorar a farmacocinética de um anticorpo, para selecionar um anticorpo, para melhorar a eficácia de anticorpos, para isolar anticorpos, para detectar vista em uma amostra e para tratar câncer
BR112021000303A2 (pt) 2018-07-11 2021-04-13 Five Prime Therapeutics, Inc. Anticorpos que se ligam a vista em ph ácido
US11213530B2 (en) * 2020-03-05 2022-01-04 Lawrence Richard Bernstein Gallium in the treatment of coronavirus disease

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CN111991559B (zh) * 2020-09-03 2022-03-22 中山大学 受体酪氨酸激酶抑制剂在制备预防和/或治疗新型冠状病毒感染药物中的应用
CN115025097A (zh) * 2022-06-30 2022-09-09 四川大学 雷替曲塞在制备靶向chmp3基因的药物中的应用

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US20230081191A1 (en) 2023-03-16
JP2023182597A (ja) 2023-12-26
US12064418B2 (en) 2024-08-20
JP2021503446A (ja) 2021-02-12
EP3706798A1 (en) 2020-09-16
JP7378395B2 (ja) 2023-11-13
AU2024278442A1 (en) 2025-01-09
WO2019087092A1 (en) 2019-05-09
CA3081675A1 (en) 2019-05-09
EA202090749A1 (ru) 2020-08-19
AU2018360389B2 (en) 2024-09-19
AU2018360389A1 (en) 2020-05-07
US11497735B2 (en) 2022-11-15
US20200289477A1 (en) 2020-09-17
KR20200084333A (ko) 2020-07-10

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Address after: bangalore

Applicant after: Aoruijin Tumor Co.,Ltd.

Applicant after: CURIS Inc.

Address before: bangalore

Applicant before: AURIGENE DISCOVERY TECHNOLOGIES Ltd.

Applicant before: CURIS Inc.