CN111373031A - 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途 - Google Patents

基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途 Download PDF

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CN111373031A
CN111373031A CN201880074245.5A CN201880074245A CN111373031A CN 111373031 A CN111373031 A CN 111373031A CN 201880074245 A CN201880074245 A CN 201880074245A CN 111373031 A CN111373031 A CN 111373031A
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J·诺维尔
E·伍德
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Jura Biology
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CN201880074245.5A 2017-11-10 2018-11-10 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途 Pending CN111373031A (zh)

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CN202410673792.2A Pending CN118530373A (zh) 2017-11-10 2018-11-10 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途

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CN110257376A (zh) * 2019-06-03 2019-09-20 上海长海医院 一种CRISPR/Cas9基因编辑方法敲除角质形成细胞中PD-L1基因的方法
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CN110872577B (zh) * 2020-01-20 2020-05-08 中国科学院动物研究所 修饰的免疫细胞及其应用
US20210268023A1 (en) * 2020-03-01 2021-09-02 The Trustees Of Columbia University In The City Of New York Enhanced CAR Tregs and Bi-Specific Antibodies for Induction of Immune Tolerance, Treating Autoimmune Diseases and Preventing Transplantation Rejection
WO2022165419A1 (en) * 2021-02-01 2022-08-04 Kyverna Therapeutics, Inc. Methods for increasing t-cell function
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US12577290B2 (en) 2021-03-04 2026-03-17 Allogene Therapeutics, Inc. FasL expression and FasR gene knockout to protect therapeutic cells from allogeneic rejection and activation-induced cell death
CN117715929A (zh) * 2021-07-29 2024-03-15 南特细胞公司 用于预防和治疗病毒感染和癌症的经修饰的t细胞受体
US20240360198A1 (en) * 2021-09-01 2024-10-31 National University Corporation Kanazawa University Immunoregulatory method, nucleic acid composition for immunoregulation, and use thereof
EP4453021A4 (en) * 2021-12-22 2025-12-31 Memorial Sloan Kettering Cancer Center CELLS EXPRESSING FAS LIGAND POLYPEPTIDES AND FAS INACTIVATION AND THEIR USES
US20250304913A1 (en) * 2022-04-06 2025-10-02 The Regents Of The University Of Colorado, A Body Corporate Chimeric antigen receptor t cells and methods of use thereof
WO2023235856A1 (en) * 2022-06-03 2023-12-07 Jura Bio, Inc Apoptosis resistant immune cells with major histocompatibility complex chimeric antigen receptor
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