CN111295202B - 治疗甲癣的外用制剂 - Google Patents

治疗甲癣的外用制剂 Download PDF

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Publication number
CN111295202B
CN111295202B CN201880071260.4A CN201880071260A CN111295202B CN 111295202 B CN111295202 B CN 111295202B CN 201880071260 A CN201880071260 A CN 201880071260A CN 111295202 B CN111295202 B CN 111295202B
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CN
China
Prior art keywords
external preparation
preparation according
active substance
fatty acid
chain fatty
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Expired - Fee Related
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CN201880071260.4A
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English (en)
Chinese (zh)
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CN111295202A (zh
Inventor
名取伸行
▲高▼部浩行
石丸卓嗣
伊関弘
唐澤圭一
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Kaken Pharmaceutical Co Ltd
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Kaken Pharmaceutical Co Ltd
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Publication of CN111295202A publication Critical patent/CN111295202A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
CN201880071260.4A 2017-10-30 2018-10-29 治疗甲癣的外用制剂 Expired - Fee Related CN111295202B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017-209136 2017-10-30
JP2017209136 2017-10-30
PCT/JP2018/040047 WO2019088005A1 (ja) 2017-10-30 2018-10-29 爪白癬治療用の外用製剤

Publications (2)

Publication Number Publication Date
CN111295202A CN111295202A (zh) 2020-06-16
CN111295202B true CN111295202B (zh) 2022-07-08

Family

ID=66333195

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CN201880071260.4A Expired - Fee Related CN111295202B (zh) 2017-10-30 2018-10-29 治疗甲癣的外用制剂

Country Status (14)

Country Link
US (1) US20210213002A1 (enExample)
EP (1) EP3705136A4 (enExample)
JP (2) JP6582158B1 (enExample)
KR (1) KR20200081432A (enExample)
CN (1) CN111295202B (enExample)
AU (1) AU2018358372A1 (enExample)
BR (1) BR112020008282A2 (enExample)
CA (1) CA3081163A1 (enExample)
IL (1) IL274100B2 (enExample)
MX (1) MX2020004491A (enExample)
RU (1) RU2020117569A (enExample)
SG (1) SG11202003820VA (enExample)
TW (1) TWI789448B (enExample)
WO (1) WO2019088005A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220119363A (ko) 2019-12-24 2022-08-29 가껭세이야꾸가부시기가이샤 에피나코나졸을 함유하는 의약
KR102217617B1 (ko) * 2020-08-14 2021-02-19 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
EP3981402A4 (en) * 2020-08-14 2022-08-10 BL&H Co., Ltd. PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF RINGWORM
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
WO2023223993A1 (ja) 2022-05-16 2023-11-23 マルホ株式会社 白癬治療用組成物
WO2025028651A1 (ja) * 2023-08-02 2025-02-06 石原産業株式会社 爪白癬用外用剤
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Citations (4)

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JP2002524495A (ja) * 1998-09-10 2002-08-06 アイ ピー アール インスティチューツ フォー ファーマクーティカル リサーチ リーエン エージー 局所適用性産物
CN101897683A (zh) * 2003-07-17 2010-12-01 敏捷治疗公司 激素透皮递送系统:组合物和方法
CN103957899A (zh) * 2011-11-04 2014-07-30 敏捷治疗公司 皮肤递送组合物和方法
CN104619320A (zh) * 2012-09-14 2015-05-13 宝丽制药股份有限公司 含有卢立康唑的药物组合物

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JPS58162514A (ja) * 1982-03-19 1983-09-27 Sumitomo Chem Co Ltd 外用ゲル製剤
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
ATE183926T1 (de) * 1993-09-29 1999-09-15 Alza Corp Hautpermeabilitaetserhöher bestehend aus monoglycerid/laktat estern
US8048919B2 (en) * 2004-06-28 2011-11-01 Archer Daniels Midland Company Use of ethyl lactate as an excipient for pharmaceutical compositions
JP5061519B2 (ja) 2006-07-12 2012-10-31 大正製薬株式会社 抗真菌剤含有ｏ／ｗエマルション組成物
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NL2003711C2 (en) * 2009-10-27 2011-04-28 Shield Mark B V Aqueous composition for topical application, method of preparation, uses and device.
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WO2012102404A1 (ja) 2011-01-30 2012-08-02 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 外用抗真菌剤
RU2694758C2 (ru) * 2012-12-20 2019-07-16 Раджив Бхушан Антимикробные композиции
JP6308137B2 (ja) * 2012-12-28 2018-04-11 大正製薬株式会社 皮膚適用製剤
CN103142458B (zh) * 2013-01-22 2015-09-09 莱普德制药有限公司 无成瘾性镇痛缓释递药系统的组方与制备方法
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KR20180052635A (ko) 2015-09-18 2018-05-18 가켄 세이야쿠 가부시키가이샤 바이아릴 유도체 및 이를 포함하는 약제
JP2017209136A (ja) 2016-05-23 2017-11-30 澁谷工業株式会社 電子線殺菌装置

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Publication number Priority date Publication date Assignee Title
JP2002524495A (ja) * 1998-09-10 2002-08-06 アイ ピー アール インスティチューツ フォー ファーマクーティカル リサーチ リーエン エージー 局所適用性産物
CN101897683A (zh) * 2003-07-17 2010-12-01 敏捷治疗公司 激素透皮递送系统:组合物和方法
JP2012092130A (ja) * 2003-07-17 2012-05-17 Agile Therapeutics Inc 経皮ホルモン送達システム：組成物および方法
CN103957899A (zh) * 2011-11-04 2014-07-30 敏捷治疗公司 皮肤递送组合物和方法
CN104619320A (zh) * 2012-09-14 2015-05-13 宝丽制药股份有限公司 含有卢立康唑的药物组合物

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Publication number Publication date
RU2020117569A3 (enExample) 2021-12-01
CN111295202A (zh) 2020-06-16
MX2020004491A (es) 2020-08-13
WO2019088005A1 (ja) 2019-05-09
AU2018358372A1 (en) 2020-05-28
RU2020117569A (ru) 2021-12-01
US20210213002A1 (en) 2021-07-15
CA3081163A1 (en) 2019-05-09
EP3705136A4 (en) 2021-08-18
TWI789448B (zh) 2023-01-11
JPWO2019088005A1 (ja) 2019-11-14
BR112020008282A2 (pt) 2020-10-20
JP6582158B1 (ja) 2019-09-25
EP3705136A1 (en) 2020-09-09
SG11202003820VA (en) 2020-05-28
JP2020011967A (ja) 2020-01-23
TW201922247A (zh) 2019-06-16
KR20200081432A (ko) 2020-07-07
IL274100B2 (en) 2023-06-01
IL274100A (en) 2020-06-30

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