BR112020008282A2 - preparação externa para tratar trichophytosis unguium - Google Patents
preparação externa para tratar trichophytosis unguium Download PDFInfo
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- BR112020008282A2 BR112020008282A2 BR112020008282-1A BR112020008282A BR112020008282A2 BR 112020008282 A2 BR112020008282 A2 BR 112020008282A2 BR 112020008282 A BR112020008282 A BR 112020008282A BR 112020008282 A2 BR112020008282 A2 BR 112020008282A2
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- Prior art keywords
- preparation
- topical
- topical preparation
- ethyl lactate
- antifungal
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- 238000002360 preparation method Methods 0.000 title claims abstract description 201
- 208000002474 Tinea Diseases 0.000 title abstract description 5
- 206010067409 Trichophytosis Diseases 0.000 title abstract description 5
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- 230000001717 pathogenic effect Effects 0.000 description 1
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- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229940069328 povidone Drugs 0.000 description 1
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- 229960001860 salicylate Drugs 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
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- 230000004936 stimulating effect Effects 0.000 description 1
- 229940086735 succinate Drugs 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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- 150000003460 sulfonic acids Chemical class 0.000 description 1
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- 235000002906 tartaric acid Nutrition 0.000 description 1
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- 229940095064 tartrate Drugs 0.000 description 1
- 229940100613 topical solution Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
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- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017209136 | 2017-10-30 | ||
| JP2017-209136 | 2017-10-30 | ||
| PCT/JP2018/040047 WO2019088005A1 (ja) | 2017-10-30 | 2018-10-29 | 爪白癬治療用の外用製剤 |
Publications (1)
| Publication Number | Publication Date |
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| BR112020008282A2 true BR112020008282A2 (pt) | 2020-10-20 |
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| BR112020008282-1A BR112020008282A2 (pt) | 2017-10-30 | 2018-10-29 | preparação externa para tratar trichophytosis unguium |
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| Country | Link |
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| US (1) | US20210213002A1 (enExample) |
| EP (1) | EP3705136A4 (enExample) |
| JP (2) | JP6582158B1 (enExample) |
| KR (1) | KR20200081432A (enExample) |
| CN (1) | CN111295202B (enExample) |
| AU (1) | AU2018358372A1 (enExample) |
| BR (1) | BR112020008282A2 (enExample) |
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| TW (1) | TWI789448B (enExample) |
| WO (1) | WO2019088005A1 (enExample) |
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| JP7709386B2 (ja) * | 2019-12-24 | 2025-07-16 | 科研製薬株式会社 | エフィナコナゾールを含有する医薬 |
| WO2022035031A1 (ko) * | 2020-08-14 | 2022-02-17 | 비엘엔에이치 주식회사 | 백선의 예방 또는 치료용 약학적 조성물 |
| KR102217617B1 (ko) * | 2020-08-14 | 2021-02-19 | 비엘엔에이치 주식회사 | 백선의 예방 또는 치료용 약학적 조성물 |
| CN116887866A (zh) | 2020-12-03 | 2023-10-13 | 巴特尔纪念研究院 | 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法 |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| AU2023271525A1 (en) | 2022-05-16 | 2024-12-05 | Maruho Co., Ltd. | Composition for treating ringworm |
| TW202519215A (zh) * | 2023-08-02 | 2025-05-16 | 日商石原產業股份有限公司 | 甲癬用外用劑 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
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| US4514385A (en) * | 1981-10-05 | 1985-04-30 | Alcon Laboratories, Inc. | Anti-acne compositions |
| JPS58162514A (ja) * | 1982-03-19 | 1983-09-27 | Sumitomo Chem Co Ltd | 外用ゲル製剤 |
| AU618517B2 (en) * | 1986-12-23 | 1992-01-02 | Eugene J. Van Scott | Additives enhancing topical actions of therapeutic agents |
| KR960704579A (ko) * | 1993-09-29 | 1996-10-09 | 에드워드 엘. 만델 | 옥시부티닌용 모노글리세리드/락테이트 에스테르 투과 촉진제(Monoglyceride/lactate Ester Permeation Enhancer for Oxybutynin) |
| JP5170486B2 (ja) * | 1998-09-10 | 2013-03-27 | バイオイコール ア−ゲー | 局所適用性産物 |
| US7384650B2 (en) * | 1999-11-24 | 2008-06-10 | Agile Therapeutics, Inc. | Skin permeation enhancement composition for transdermal hormone delivery system |
| US8048919B2 (en) * | 2004-06-28 | 2011-11-01 | Archer Daniels Midland Company | Use of ethyl lactate as an excipient for pharmaceutical compositions |
| JP5061519B2 (ja) | 2006-07-12 | 2012-10-31 | 大正製薬株式会社 | 抗真菌剤含有ｏ／ｗエマルション組成物 |
| ES2588188T3 (es) | 2007-08-27 | 2016-10-31 | Nihon Nohyaku Co., Ltd. | Agente para la dermatitis fúngica |
| NL2003711C2 (en) * | 2009-10-27 | 2011-04-28 | Shield Mark B V | Aqueous composition for topical application, method of preparation, uses and device. |
| NL2003786C2 (en) * | 2009-11-11 | 2010-07-30 | Medner B V | COMPOSITION FOR TOPICAL APPLICATION, USES THEREOF, APPLICATOR DEVICE AND KIT OF PARTS. |
| CA2825889C (en) * | 2011-01-30 | 2015-06-02 | Meiji Seika Pharma Co., Ltd. | Topical antifungal agent |
| EA026664B1 (ru) * | 2011-11-04 | 2017-05-31 | Эджайл Терапьютикс, Инк. | Композиция и устройство для трансдермальной доставки прогестина |
| JP5686874B2 (ja) * | 2012-09-14 | 2015-03-18 | 株式会社ポーラファルマ | 医薬組成物 |
| EP2941128B1 (en) * | 2012-12-20 | 2023-06-28 | Rajiv Bhushan | Antimicrobial compositions |
| JP6308137B2 (ja) * | 2012-12-28 | 2018-04-11 | 大正製薬株式会社 | 皮膚適用製剤 |
| CN103142458B (zh) * | 2013-01-22 | 2015-09-09 | 莱普德制药有限公司 | 无成瘾性镇痛缓释递药系统的组方与制备方法 |
| CA2931144C (en) * | 2013-11-22 | 2020-02-04 | Dow Pharmaceutical Sciences, Inc. | Anti-infective methods, compositions, and devices |
| JP5623671B1 (ja) * | 2014-07-23 | 2014-11-12 | 株式会社ポーラファルマ | ルリコナゾールを含有する製剤の評価方法及び指標物質 |
| KR20180052635A (ko) | 2015-09-18 | 2018-05-18 | 가켄 세이야쿠 가부시키가이샤 | 바이아릴 유도체 및 이를 포함하는 약제 |
| JP2017209136A (ja) | 2016-05-23 | 2017-11-30 | 澁谷工業株式会社 | 電子線殺菌装置 |
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- 2018-10-29 WO PCT/JP2018/040047 patent/WO2019088005A1/ja not_active Ceased
- 2018-10-29 SG SG11202003820VA patent/SG11202003820VA/en unknown
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- 2018-10-29 CA CA3081163A patent/CA3081163A1/en active Pending
- 2018-10-29 AU AU2018358372A patent/AU2018358372A1/en not_active Abandoned
- 2018-10-29 EP EP18872316.7A patent/EP3705136A4/en not_active Withdrawn
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- 2018-10-29 CN CN201880071260.4A patent/CN111295202B/zh not_active Expired - Fee Related
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2019
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2020
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Also Published As
| Publication number | Publication date |
|---|---|
| JP6582158B1 (ja) | 2019-09-25 |
| JP2020011967A (ja) | 2020-01-23 |
| SG11202003820VA (en) | 2020-05-28 |
| CA3081163A1 (en) | 2019-05-09 |
| WO2019088005A1 (ja) | 2019-05-09 |
| IL274100B2 (en) | 2023-06-01 |
| EP3705136A1 (en) | 2020-09-09 |
| US20210213002A1 (en) | 2021-07-15 |
| EP3705136A4 (en) | 2021-08-18 |
| MX2020004491A (es) | 2020-08-13 |
| AU2018358372A1 (en) | 2020-05-28 |
| RU2020117569A (ru) | 2021-12-01 |
| JPWO2019088005A1 (ja) | 2019-11-14 |
| CN111295202B (zh) | 2022-07-08 |
| CN111295202A (zh) | 2020-06-16 |
| RU2020117569A3 (enExample) | 2021-12-01 |
| IL274100A (en) | 2020-06-30 |
| TW201922247A (zh) | 2019-06-16 |
| KR20200081432A (ko) | 2020-07-07 |
| TWI789448B (zh) | 2023-01-11 |
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