CN111265435A - No-clean bacteriostatic hand sanitizer containing navel orange essential oil and preparation method thereof - Google Patents
No-clean bacteriostatic hand sanitizer containing navel orange essential oil and preparation method thereof Download PDFInfo
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- CN111265435A CN111265435A CN202010210943.2A CN202010210943A CN111265435A CN 111265435 A CN111265435 A CN 111265435A CN 202010210943 A CN202010210943 A CN 202010210943A CN 111265435 A CN111265435 A CN 111265435A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/022—Refining
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/025—Recovery by solvent extraction
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Abstract
The invention discloses a washing-free bacteriostatic hand sanitizer containing navel orange essential oil and a preparation method thereof, wherein the raw materials comprise: ethanol, glycerol, squalane, carbomer, kaempferol, essence, benzalkonium chloride, essential oil and deionized water. The essential oil in the formula is navel orange essential oil prepared by a physical squeezing method, the color is bright yellow and clear, and the smell is sweet orange fragrance. The citrus essential oil has good bacteriostatic action, and the essential oil prepared by a physical method has no chemical harmful components, and is safe and natural. The addition of the essential oil can enhance the bacteriostatic effect of the ethanol, and endow the product with fresh citrus fragrance, so that the bacteriostatic effect can be achieved to a certain extent, and the skin can be prevented from being irritated and damaged. The product does not need to be heated, and can be stirred at a constant speed by a digital display stirrer at room temperature, so that the process is simple and the cost is low.
Description
Technical Field
The invention belongs to the field of daily-use chemistry, relates to a hand sanitizer, and particularly relates to a no-clean bacteriostatic hand sanitizer containing navel orange essential oil and a preparation method thereof.
Background
Nowadays, with the gradual increase of consumption level, people not only have strong decontamination capability but also have good use feeling and safety for daily chemical products. The environmental protection is gradually paid attention to by people, and products containing pure natural components are more favored by consumers. The navel orange essential oil prepared by a physical squeezing method is added in the product, the antibacterial effect is proved by experiments, and the product has sweet fragrance and can bring pleasure to users.
As is well known, navel oranges are citrus varieties with rich yield in China, the navel oranges are used as fruits, the sales volume is high, but the utilization rate of peel is low. If the fresh fruit peel can be collected and oil extracted for daily chemical products, the effect can be promoted and the environment-friendly effect can be achieved. The purpose of the hand sanitizer is to improve the portability of the hand sanitizer for daily use.
Disclosure of Invention
The invention aims to provide a washing-free bacteriostatic hand sanitizer containing navel orange essential oil and a preparation method thereof, wherein the washing-free bacteriostatic hand sanitizer has a remarkable bacteriostatic effect and good fruit fragrance.
In order to achieve the purpose, the invention provides a washing-free antibacterial hand sanitizer containing navel orange essential oil, which is characterized by comprising the following raw materials in percentage by mass:
preferably, the no-clean bacteriostatic hand sanitizer containing navel orange essential oil comprises the following raw materials in percentage by mass:
preferably, the no-clean bacteriostatic hand sanitizer containing navel orange essential oil comprises the following raw materials in percentage by mass:
preferably, the navel orange essential oil is obtained by a physical squeezing method, is natural and safe, and has no harmful chemical components.
The invention also provides a preparation method of the washing-free antibacterial hand sanitizer containing the navel orange essential oil, which is characterized by comprising the following steps:
step 1: putting carbomer and deionized water into a clean container according to the mass percentage, uniformly stirring by using a digital display stirrer, then sequentially adding 47-50% of absolute ethyl alcohol, 8-10.5% of glycerol and 1-1.5% of squalane, and continuously stirring;
step 2: when the system is stirred uniformly, adding 0.1-0.5% of Kathon and 0.1% of benzalkonium chloride by mass percent, and continuously stirring for 10-20 min;
and step 3: adding 0.8-1% of essence and 1-5% of navel orange essential oil into the system by mass percent, and uniformly stirring to obtain the no-clean bacteriostatic hand sanitizer containing the navel orange essential oil.
Preferably, the preparation of the navel orange essential oil comprises the following steps: peeling off peel of fresh navel orange to remove white fiber, and avoiding breaking oil sac; putting the pericarp in a container, adding water, adding calcium bicarbonate, and soaking for 30-40min, wherein the addition amount of calcium bicarbonate is 0.3% of the weight of pericarp, and the addition amount of water is 4 times of the weight of pericarp; washing the soaked peel, washing away calcium hydroxide, squeezing, adding 0.15% sodium chloride into peel slurry, stirring, standing, and precipitating; collecting the oil stains when the oil stains float on the liquid, and centrifuging for 15min at 9000 r/min; and (4) collecting the essential oil after the centrifugation is finished, and adding anhydrous sodium sulfate to remove water to obtain the navel orange essential oil.
The invention has the beneficial effects that:
the invention contains natural plant essential oil, the extraction method of the essential oil is a physical method, the skin cannot be damaged, the product can be endowed with fresh fruit fragrance, and the use feeling is improved to a certain extent. The components in the formula are safe, and the added humectant can prevent chapped skin. The citrus essential oil has good bacteriostatic effect and can play a role in protection.
Drawings
Fig. 1 is a bacteriostatic effect diagram of the no-clean bacteriostatic hand sanitizer containing navel orange essential oil prepared in example 1.
Detailed Description
The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Further, it should be understood that various changes or modifications of the present invention may be made by those skilled in the art after reading the teaching of the present invention, and such equivalents may fall within the scope of the present invention as defined in the appended claims.
The percentages of the components in the embodiments of the invention are mass percentages.
The preparation of the navel orange essential oil in each embodiment of the invention specifically comprises the following steps:
step 1: peeling off peel of fresh navel orange to remove white fiber, avoiding breaking oil sac, and weighing 100g peel;
step 2: putting the pericarp in a container, adding 400mL of water, adding 0.3g of calcium bicarbonate, and soaking for 30-40min, wherein the addition amount of calcium bicarbonate is 0.3% of the weight of pericarp, and the addition amount of water is 4 times of the weight of pericarp;
and step 3: washing the soaked peel to remove calcium hydroxide, squeezing with a Jiuyang juice machine, adding 0.15% sodium chloride into the peel slurry, stirring, standing, and precipitating;
and 4, step 4: after 5min, the oil bloom can be seen to float on the liquid, the oil bloom is collected to a 45mL centrifuge tube, balanced and centrifuged at 9000r/min for 15 min;
and 5: and (4) collecting the essential oil after the centrifugation is finished, and adding anhydrous sodium sulfate to remove water to obtain the navel orange essential oil.
Example 1
The embodiment provides a preparation method of a no-clean bacteriostatic hand sanitizer containing navel orange essential oil, which comprises the following specific steps:
step 1: putting 2% of carbomer and deionized water which are weighed according to a proportion into a clean container, uniformly stirring by using a digital display stirrer, then sequentially adding 50% of absolute ethyl alcohol, 9% of glycerol and 1.5% of squalane, and continuously stirring;
step 2: adding 0.2% of Kathon and 0.1% of benzalkonium chloride when the system is stirred uniformly, and continuing stirring for 15 min;
and step 3: and finally, adding 1% of essence and 3% of navel orange essential oil into the system, and uniformly stirring to obtain the no-clean bacteriostatic hand sanitizer containing the navel orange essential oil.
The formula of the no-clean hand sanitizer in the embodiment 1 has high ethanol content and better sterilization effect, can be quickly evaporated after being applied to hands, and is dry and non-sticky. The hand sanitizer can effectively sterilize and tighten skin.
The bacteriostasis test method of the washing-free bacteriostatic hand sanitizer containing the navel orange essential oil comprises the following steps:
(1) firstly, sterilizing a prepared NA culture medium (the NA culture medium is purchased from an exploration platform, and the product number is HB0109-7) at 121 ℃ under high pressure, cooling to 50 ℃ after 20min, and pouring the mixture into a flat plate for natural solidification;
(2) the staphylococcus aureus bacterial suspension is subjected to gradient dilution (the total number of colonies is about 10)5-106) Respectively sucking 0.1 ml of bacterial liquid on a flat plate by using 0.2 ml of sterile pipettes, and respectively and uniformly coating the bacterial liquid on a culture medium by using a sterile coating rod;
(3) and (3) attaching a filter paper sheet coated with the washing-free bacteriostatic hand sanitizer containing the navel orange essential oil to the flat plate by using sterile tweezers, and observing whether a bacteriostatic circle exists or not, wherein as shown in figure 1, the bacteriostatic circle can be seen from the figure, so that the washing-free bacteriostatic hand sanitizer containing the navel orange essential oil has a bacteriostatic action.
Example 2
The embodiment provides a preparation method of a no-clean bacteriostatic hand sanitizer containing navel orange essential oil, which comprises the following specific steps:
step 1: putting 2.5% of carbomer and deionized water which are weighed according to the proportion into a clean container, uniformly stirring by using a digital display stirrer, then sequentially adding 48% of absolute ethyl alcohol, 10.5% of glycerol and 1.5% of squalane, and continuously stirring;
step 2: adding 0.2% of Kathon and 0.1% of benzalkonium chloride when the system is stirred uniformly, and continuing stirring for 15 min;
and step 3: and finally, adding 1% of essence and 3% of navel orange essential oil into the system, and uniformly stirring to obtain the no-clean bacteriostatic hand sanitizer containing the navel orange essential oil.
The ethanol content of the leave-on hand sanitizer formulation of example 2 was slightly reduced in order to care for skin sensitive users. Even if the alcohol content is reduced, the sterilizing effect is still good. Increasing the humectant content can further moisturize the skin.
Claims (5)
1. A washing-free bacteriostatic hand sanitizer containing navel orange essential oil is characterized by comprising the following raw materials in percentage by mass:
2. the washing-free bacteriostatic hand sanitizer containing navel orange essential oil according to claim 1, which comprises the following raw materials in percentage by mass:
3. the washing-free bacteriostatic hand sanitizer containing navel orange essential oil according to claim 1, which comprises the following raw materials in percentage by mass:
4. the preparation method of the navel orange essential oil-containing no-clean bacteriostatic hand sanitizer according to any one of claims 1 to 3, which is characterized by comprising the following steps:
step 1: putting carbomer and deionized water into a clean container according to the mass percentage, uniformly stirring by using a digital display stirrer, then sequentially adding 47-50% of absolute ethyl alcohol, 8-10.5% of glycerol and 1-1.5% of squalane, and continuously stirring;
step 2: when the system is stirred uniformly, adding 0.1-0.5% of Kathon and 0.1% of benzalkonium chloride by mass percent, and continuously stirring for 10-20 min;
and step 3: adding 0.8-1% of essence and 1-5% of navel orange essential oil into the system by mass percent, and uniformly stirring to obtain the no-clean bacteriostatic hand sanitizer containing the navel orange essential oil.
5. The method for preparing a no-clean bacteriostatic hand sanitizer containing navel orange essential oil according to claim 4, wherein the preparation of the navel orange essential oil comprises the following steps: peeling off peel of fresh navel orange to remove white fiber, and avoiding breaking oil sac; putting the pericarp in a container, adding water, adding calcium bicarbonate, and soaking for 30-40min, wherein the addition amount of calcium bicarbonate is 0.3% of the weight of pericarp, and the addition amount of water is 4 times of the weight of pericarp; washing the soaked peel, washing away calcium hydroxide, squeezing, adding 0.15% sodium chloride into peel slurry, stirring, standing, and precipitating; collecting the oil stains when the oil stains float on the liquid, and centrifuging for 15min at 9000 r/min; and (4) collecting the essential oil after the centrifugation is finished, and adding anhydrous sodium sulfate to remove water to obtain the navel orange essential oil.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010210943.2A CN111265435A (en) | 2020-03-24 | 2020-03-24 | No-clean bacteriostatic hand sanitizer containing navel orange essential oil and preparation method thereof |
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| CN202010210943.2A CN111265435A (en) | 2020-03-24 | 2020-03-24 | No-clean bacteriostatic hand sanitizer containing navel orange essential oil and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113616577A (en) * | 2021-07-23 | 2021-11-09 | 广州市柏菲化妆品有限公司 | Wash-free hand sanitizer |
| CN116286192A (en) * | 2023-03-28 | 2023-06-23 | 广西冰客食品有限公司 | Process for producing Wo orange peel oil |
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| CN102586023A (en) * | 2012-01-19 | 2012-07-18 | 仲恺农业工程学院 | Method for extracting citrus pericarp essential oil |
| CN104173248A (en) * | 2014-09-05 | 2014-12-03 | 中华全国供销合作总社南京野生植物综合利用研究院 | Natural plant essential oil-containing disinfecting liquid soap, as well as preparation method and application thereof |
| CN106318644A (en) * | 2016-11-02 | 2017-01-11 | 赣南师范大学 | Preparation method of navel orange essential oil molecule distillation component |
| CN107937139A (en) * | 2017-12-30 | 2018-04-20 | 农广善 | A kind of method of Peel of Navel Orange extraction essential oil |
-
2020
- 2020-03-24 CN CN202010210943.2A patent/CN111265435A/en active Pending
Patent Citations (4)
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| CN102586023A (en) * | 2012-01-19 | 2012-07-18 | 仲恺农业工程学院 | Method for extracting citrus pericarp essential oil |
| CN104173248A (en) * | 2014-09-05 | 2014-12-03 | 中华全国供销合作总社南京野生植物综合利用研究院 | Natural plant essential oil-containing disinfecting liquid soap, as well as preparation method and application thereof |
| CN106318644A (en) * | 2016-11-02 | 2017-01-11 | 赣南师范大学 | Preparation method of navel orange essential oil molecule distillation component |
| CN107937139A (en) * | 2017-12-30 | 2018-04-20 | 农广善 | A kind of method of Peel of Navel Orange extraction essential oil |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113616577A (en) * | 2021-07-23 | 2021-11-09 | 广州市柏菲化妆品有限公司 | Wash-free hand sanitizer |
| CN116286192A (en) * | 2023-03-28 | 2023-06-23 | 广西冰客食品有限公司 | Process for producing Wo orange peel oil |
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Application publication date: 20200612 |