CN111249310A - 一种紫梢花提取及制备骨针的方法 - Google Patents
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Abstract
本发明公开了一种紫梢花提取及制备骨针的方法，包括以下步骤：取紫梢花原料后加水煎煮，收集煎液，浓缩，喷雾干燥，80‑200目过筛后得到紫梢花提取物，收集药渣后将药渣用稀酸在搪瓷罐中保温，20‑180目过滤，精制，干燥，80‑200目过筛后制成骨针成品。本发明不仅获取了紫梢花提取物，成分跟常规的有一定差别，还利用药渣制备出了海绵骨针，此方法会涉及到废水污染，本发明前期水提后再对剩下的药渣进行处理，对剩下的药渣再加工所用到的稀酸的量都大大的减少，这样极大地减少了废水的产生，也充分利用了天然资源的中药材。
Description
技术领域
本发明涉及海绵骨针领域，具体涉及一种紫梢花提取及制备骨针的方法。
背景技术
海绵动物属于多孔动物门，俗称海绵，是最简单的多细胞动物，它们没有明确的器官结构，但中胶层发达，其中的细胞具有全能性。海绵中与其它后生动物相比，海绵细胞呈现出高度的独立性。海绵主要营固着生活，体内有一套特有的水沟系统，是其摄食、呼吸、排泄、生殖等生命活动的主要通道。由于成体海绵营固着或附着生活，不具备运动能力。骨针(spiculers)是由海绵动物体内一种具有富集并有条理地沉淀硅或钙能力的造骨细胞(sclerocytes)分泌产生，它们是一种特殊中胶层细胞，分布于中胶层中。
目前市面上有很多生产紫梢花(海绵动物)提取物和少许海绵骨针纯化的，他们都是只做了提取物或者只做了海绵骨针纯化的其中某一部分，没有把这个原料充分、有效的完全利用起来，由于该原料目前尚属于天然不能人工种植的，资源有限所以存在资源浪费。
目前市面上紫梢花提取物成分：含海绵硬蛋白、海绵异硬蛋白、磷酸盐、碳酸盐等。作用：益阳涩精、治阳痿、遗精、白浊、带下、小便不禁、阴囊湿疹，最终成品紫梢花提取物在药品、保健品和保健食品中都可以广泛运用。
不论是CN105858669B，还是CN108163861A生产的海绵骨针由于没有经过处理水提，而加入酸或者其它溶剂所产生的废水是需要再处理-增加污水处理成本，同时在一定程度上对骨针的提纯有一定干扰，在提纯骨针的过程中设备/能耗投入更大，产生的废水更多。
发明内容
为解决现有技术中存在的问题，本发明提供了一种紫梢花提取及制备骨针的方法，解决了上述背景技术中提到的问题。
为实现上述目的，本发明提供如下技术方案：一种紫梢花提取及制备骨针的方法，包括以下步骤：取紫梢花原料后加水煎煮，收集煎液，浓缩，喷雾干燥，80-200目过筛后得到紫梢花提取物，收集药渣后将药渣用稀酸在搪瓷罐中保温，20-180目过滤，精制，干燥，80-200目过筛后制成骨针成品。
优选的，所述的加水煎煮是加水煎煮2次，第一次是加8倍量的水浸渍60-90分钟后煎煮，第二次是加6倍量的水后煎煮。
优选的，所述的煎煮的温度是80-85℃，煎煮的时间是40-60min。
优选的，所述的收集煎液是收集2次的煎液后合并煎液。
优选的，所述的浓缩是浓缩到比重1.1000-1.1008g/cm3。
优选的，所述的喷雾干燥温度为90-93℃。
优选的，所述的药渣稀酸保温中的稀酸浓度为10-15％，保温时间为3-4h，所述稀酸是稀盐酸或稀硫酸
优选的，所述的精制是加入生产用水、NaoH中的至少一种来稀释中和稀酸，保证产品PH值在6-9之间。
优选的，所述的干燥温度为60-80℃。
优选的，所述的紫梢花提取物由如下质量百分含量的组分组成：碳水化合物75-80％、淫羊藿苷10-15％、蛋白质8-10％。
本发明的有益效果是：本发明不仅获取了紫梢花提取物，成分跟常规的有一定差别，还利用药渣制备出了海绵骨针，此方法会涉及到废水污染，本发明前期水提后再对剩下的药渣进行处理，对剩下的药渣再加工所用到的稀酸的量减少40-60％，废水的量减少50％以上，也充分利用了天然资源的中药材。
附图说明
图1为本发明的制备流程图
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
请参阅图1，本发明提供一种技术方案：一种紫梢花提取及制备骨针的方法，包括以下步骤：取紫梢花原料后加水煎煮，收集煎液，浓缩，喷雾干燥，80-200目过筛后得到紫梢花提取物，收集药渣后将药渣用稀酸在搪瓷罐中保温，20-180目过滤，精制，干燥，80-200目过筛后制成骨针成品。
进一步的，所述的加水煎煮是加水煎煮2次，第一次是加8倍量的水浸渍60-90分钟后煎煮，第二次是加6倍量的水后煎煮。
进一步的，所述的煎煮的温度是80-85℃，煎煮的时间是40-60min。
进一步的，所述的收集煎液是收集2次的煎液后合并煎液。
进一步的，所述的浓缩是浓缩到比重1.1000-1.1008g/cm3。
进一步的，所述的喷雾干燥温度为90-93℃。
进一步的，所述的药渣稀酸保温中的稀酸浓度为10-15％，保温时间为3-4h，所述稀酸是稀盐酸或稀硫酸。
进一步的，所述的精制是加入生产用水、NaoH中的至少一种来稀释中和稀酸，保证产品PH值在6-9之间。
进一步的，所述的干燥温度为60-80℃。
进一步的，所述的紫梢花提取物由如下质量百分含量的组分组成：碳水化合物75-80％、淫羊藿苷10-15％、蛋白质8-10％。
碳水化合物是生命细胞结构的主要成分及主要供能物质，有调节细胞活动的重要功能，参与细胞的组成，还有节约蛋白质、抗生酮、解毒和增强肠道功能的作用；淫羊藿苷具有补肾壮阳、抗衰老等功能；蛋白质是组成人体一切细胞、组织的重要成分约占人体全部质量的18％。
尽管参照前述实施例对本发明进行了详细的说明，对于本领域的技术人员来说，其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换,凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (10)
1.一种紫梢花提取及制备骨针的方法，其特征在于，包括以下步骤：取紫梢花原料后加水煎煮，收集煎液，浓缩，喷雾干燥，80-200目过筛后得到紫梢花提取物，收集药渣后将药渣用稀酸在搪瓷罐中保温，20-180目过滤，精制，干燥，80-200目过筛后制成骨针成品。
2.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的加水煎煮是加水煎煮2次，第一次是加8倍量的水浸渍60-90分钟后煎煮，第二次是加6倍量的水后煎煮。
3.根据权利要求2所述的紫梢花提取及制备骨针的方法，其特征在于：所述的煎煮的温度是80-85℃，煎煮的时间是40-60min。
4.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的收集煎液是收集2次的煎液后合并煎液。
5.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的浓缩是浓缩到比重1.1000-1.1008g/cm3。
6.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的喷雾干燥温度为90-93℃。
7.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的药渣稀酸保温中的稀酸浓度为10-15％，保温时间为3-4h，所述稀酸是稀盐酸或稀硫酸。
8.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的精制是加入生产用水、NaoH中的至少一种来稀释中和稀酸，保证产品PH值在6-9之间。
9.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的干燥温度为60-80℃。
10.根据权利要求1所述的紫梢花提取及制备骨针的方法，其特征在于：所述的紫梢花提取物由如下质量百分含量的组分组成：碳水化合物75-80％、淫羊藿苷10-15％、蛋白质8-10％。
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| US20130309315A1 (en) * | 2002-07-01 | 2013-11-21 | Maria Villani | Porifera-based therapeutic compositions for treating and preventing skin diseases |
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