CN111228156A - Body odor spray containing Australian tea tree essential oil and preparation method thereof - Google Patents

Body odor spray containing Australian tea tree essential oil and preparation method thereof Download PDF

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Publication number
CN111228156A
CN111228156A CN202010210911.2A CN202010210911A CN111228156A CN 111228156 A CN111228156 A CN 111228156A CN 202010210911 A CN202010210911 A CN 202010210911A CN 111228156 A CN111228156 A CN 111228156A
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essential oil
essence
tea tree
body odor
tree essential
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杨子雄
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Fujian Hailewei Bio Engineering Co ltd
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Fujian Hailewei Bio Engineering Co ltd
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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Abstract

The invention relates to the technical field of medicines, and particularly relates to a body odor spray containing Australian tea tree essential oil and a preparation method thereof. The preparation raw materials at least comprise the following components in parts by weight: 60-80 parts of water, 0.5-2 parts of essential oil, 2-5 parts of emulsifier, 10-40 parts of ethanol, 0.05-0.3 part of antibacterial agent, 0.05-0.2 part of chelate, 0.05-0.2 part of bactericide and 0.05-0.2 part of essence; the bromhidrosis spray provided by the invention is harmless to human bodies, has no toxic or side effect, is remarkable in effect, simple in preparation method and using method, and has a unique curative effect on bromhidrosis.

Description

Body odor spray containing Australian tea tree essential oil and preparation method thereof
Technical Field
The invention relates to the technical field of medicines, and particularly relates to a body odor spray containing Australian tea tree essential oil and a preparation method thereof.
Background
Bromhidrosis, also known as bromhidrosis and body odor, body gas and axillary qi, is a foul and smelly odor generated by decomposition of skin surface bacteria (such as gram-positive bacteria) from volatile fatty acids generated in apocrine secretion distributed on body surface skin such as axilla, perineum, and upper back.
Bromhidrosis is a skin disease, also called bromhidrosis, stink, body gas and axillary qi, and the pathogenesis is hypersecretion of apocrine glands, which are special glands of mammals. The secretion is in the form of a semi-liquid. The secretion has odor, and in addition, the apocrine sweat gland cells are damaged and shed in different degrees in the secretion process, and then are deteriorated and putrefactive through the action of bacteria, so that a strong odor is given out and becomes the main component of body odor. After a large amount of secretion is accumulated on the surface of the skin, a unique odor can be emitted under the influence of bacterial decomposition, and the work and the study of people around a patient are influenced, and meanwhile, a heavy psychological burden is brought to the patient.
At present, the clinical treatment modes of the bromhidrosis are relatively more, and the bromhidrosis has various advantages and disadvantages, more medicines for treating the bromhidrosis at home and abroad are provided, and western medicines and traditional Chinese medicines are provided, but the bromhidrosis has the defects of high medicine price, unsatisfactory treatment effect and the like.
Disclosure of Invention
In order to solve the technical problems, the invention provides a body odor spray containing Australia tea tree essential oil, which is prepared from the following raw materials in parts by weight: 60-80 parts of water, 0.5-2 parts of essential oil, 2-5 parts of emulsifier, 10-40 parts of ethanol, 0.05-0.3 part of antibacterial agent, 0.05-0.2 part of chelate, 0.05-0.2 part of bactericide and 0.05-0.2 part of essence.
As a preferable technical scheme, the essence is a flower fragrance type essence.
As a preferred technical solution of the present invention, the floral essence is selected from one or more of rose essence, jasmine essence, clove essence, sunflower essence, orange flower essence, gardenia essence and lavender essence.
As a preferable technical scheme of the invention, the emulsifier is a nonionic surfactant.
As a preferable technical scheme of the invention, the nonionic surfactant is selected from one or more of long-chain fatty alcohol-polyoxyethylene ether, castor oil-polyoxyethylene ether, lauryl amine-polyoxyethylene ether and hydrogenated castor oil.
In a preferred embodiment of the present invention, the nonionic surfactant is hydrogenated castor oil.
In a preferred embodiment of the present invention, the antibacterial agent is selected from one or more of zinc isooctanoate, zinc undecylenate, undecylenic acid monoethanolamide, and triclosan.
In a preferred embodiment of the present invention, the chelate is one or more selected from the group consisting of ethylenediaminetetraacetic acid, aminotrimethylenephosphonic acid, citric acid, gluconic acid, iminodiacetic acid, and EDTA-2 Na.
As a preferable technical scheme of the invention, the bactericide is selected from one or more of phenoxyethanol, ethylhexyl glycerol, nano silver powder, cationic polyacrylamide and hydantoin.
The second aspect of the invention provides a preparation method of a body odor spray containing Australia tea tree essential oil, which comprises the following steps:
(1) completely dissolving water and chelate till the solution is transparent to obtain a mixed solution 1;
(2) mixing and stirring the essential oil, the emulsifier, the ethanol and the bactericide until the mixture is transparent to obtain a mixed solution 2;
(3) and adding the mixed solution 2 into the mixed solution 1, stirring until the mixed solution is transparent, finally adding the bactericide, and stirring until the mixed solution is transparent.
Has the advantages that: the invention provides a bromhidrosis spray containing Australian tea tree essential oil and a preparation method thereof, wherein the components in the formula are mutually coordinated through special selection and proportion regulation of essence, emulsifier, antibacterial agent, chelating agent, bactericide and essence, the percutaneous absorption and permeation capability of active ingredients is increased, the medicine effect is generated on an affected part, bromhidrosis bacteria can be killed, the bacteria decomposition is inhibited, the skin is refreshed, and the effects of body cleaning, fragrance generation, deodorization, perspiration suppression, bacteria prevention and sterilization can be achieved. In addition, the bromhidrosis spray provided by the invention is harmless to human bodies, has no toxic or side effect, is remarkable in effect, simple in preparation method and using method, and has a unique curative effect on bromhidrosis.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.
Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
In order to solve the technical problems, the invention provides a body odor spray containing Australia tea tree essential oil, which is prepared from the following raw materials in parts by weight: 60-80 parts of water, 0.5-2 parts of essential oil, 2-5 parts of emulsifier, 10-40 parts of ethanol, 0.05-0.3 part of antibacterial agent, 0.05-0.2 part of chelate, 0.05-0.2 part of bactericide and 0.05-0.2 part of essence.
In a more preferable embodiment, the preparation raw materials at least comprise 67-75 parts of water, 0.8-1.5 parts of essential oil, 2.5-4 parts of emulsifier, 20-30 parts of ethanol, 0.1-0.25 part of antibacterial agent, 0.08-0.13 part of chelate, 0.08-0.13 part of bactericide and 0.08-0.13 part of essence.
In a most preferred embodiment, the preparation raw materials at least comprise 70.5 parts of water, 1 part of essential oil, 3 parts of emulsifier, 25 parts of ethanol, 0.2 part of antibacterial agent, 0.1 part of chelate, 0.1 part of bactericide and 0.1 part of essence.
Essential oil
In a more preferred embodiment, the essential oil of the present invention is tea tree essential oil.
The tea tree essential oil is native to Australia and is an extract of tea trees. Has antibacterial, antiinflammatory, pore astringing, common cold, cough, rhinitis, asthma treating, dysmenorrhea improving, menoxenia and genital infection relieving effects. It is suitable for oily and acne skin, and can be used for treating suppurative wound, burn, sunburn, tinea pedis, and dandruff. The most important chemical components are p-menthene (terpinene), terpineol (pinene), limonene (limone), cineol (cineole), terpineol (terpineol) and anisic acid (cumene).
In a most preferred embodiment, the tea tree essential oil of the present invention is Australian tea tree essential oil, which is commercially available from a manufacturer including, but not limited to, Guangzhou sanderi Biotech limited.
Emulsifier
The emulsifier of the present invention is a compound capable of forming a stable emulsion from a mixture of two or more mutually incompatible components.
In a preferred embodiment, the emulsifier of the present invention is a nonionic surfactant.
In a more preferred embodiment, the nonionic surfactant of the present invention is selected from one or more of long-chain fatty alcohol polyoxyethylene ether, castor oil polyoxyethylene ether, lauryl amine polyoxyethylene ether and hydrogenated castor oil.
In a most preferred embodiment, the nonionic surfactant of the present invention is hydrogenated castor oil.
The hydrogenated castor oil of the present invention is a white to yellowish chemical substance in the form of powder, block or flake.
The hydrogenated castor oil of the present invention is commercially available from a manufacturer including, but not limited to Xiamen, Fine Limited, model number PEG-40.
Antibacterial agent
The antibacterial agent of the present invention is a chemical substance capable of maintaining the growth or reproduction of certain microorganisms (bacteria, fungi, yeasts, algae, viruses, etc.) at a level below a necessary level for a certain period of time. An antimicrobial agent is a substance or product having bacteriostatic and bactericidal properties.
In a preferred embodiment the antibacterial agent according to the invention is selected from one or more of zinc iso-octoate, zinc undecylenate, undecylenate monoethanolamide, triclosan.
In a more preferred embodiment, the antimicrobial agent of the present invention is triclosan.
The triclosan of the present invention is commercially available from a manufacturer including, but not limited to, Xiamen, Inc. at the grade of DP-300 (Yujiehun).
The triclosan has the chemical molecular formula of C12H7Cl3O2Also known as triclosan and triclosan, triclosan is a white or off-white crystalline powder in the normal state with a slight phenolic odor. Is insoluble in water and easily soluble in alkali liquor and organic solvent. It is a high-effective broad-spectrum antibacterial agent, and has killing and inhibiting effects on gram-positive bacteria, gram-negative bacteria, yeast and virus. It decomposes rapidly in nature, and thus has a low chance of developing resistance problems.
Chelate compound
The chelate compound of the present invention is a compound which forms a complex ion with a metal ion.
In a preferred embodiment, the chelate according to the invention is selected from one or more of ethylenediaminetetraacetic acid, aminotrimethylenephosphonic acid, citric acid, gluconic acid, iminodiacetic acid, EDTA-2 Na.
In a most preferred embodiment, the chelate of the present invention is EDTA-2 Na.
EDTA-2Na according to the present invention is commercially available from commercial suppliers including, but not limited to Xiamen, Li Ltd.
The EDTA-2Na is also called as disodium ethylene diamine tetraacetate, is a good compounding agent in chemistry, has six coordination atoms, forms a compounding agent called as chelate, and is white crystal particles or powder which is odorless and tasteless. It is water soluble and very insoluble in ethanol. It is an important chelating agent that chelates metal ions in solution.
Bactericide
The bactericide of the present invention is also called biocide, bactericidal algicide, microbicide, etc., and generally refers to a chemical agent that is effective in controlling or killing microorganisms-bacteria, fungi and algae in an aqueous system.
In a preferred embodiment, the bactericide is selected from one or more of phenoxyethanol, ethylhexyl glycerol, silver nanopowder, cationic polyacrylamide and hydantoin.
In a most preferred embodiment, the biocide of the invention is a hydantoin.
The hydantoins of the present invention are commercially available from manufacturers including, but not limited to Xiamen, Li, Inc. under the trade name Gallandan.
Essence
The essence disclosed by the invention is a flower-fragrance essence.
In a preferred embodiment, the floral essence of the present invention is selected from one or more of rose essence, jasmine essence, clove essence, sunflower essence, orange flower essence, gardenia essence, lavender essence.
In a preferred embodiment, the essence of the present invention is a jasmine essence.
The jasmine essence of the present invention is commercially available from a variety of companies including, but not limited to, Allen (Shanghai) essence and spice, Inc. under the brand name PD-164A.
The inventor finds in experiments that the body odor spray with fragrance, sterilization effect and good body odor removing effect is obtained by taking water and ethanol as solvents, adding Australia tea tree essential oil, an emulsifier, an antibacterial agent, a chelating agent, a bactericide and essence and reasonably selecting the type and the proportion of the substances. The invention adopts PEG-40 hydrogenated castor oil as an emulsifier, which not only can uniformly disperse oily substances such as essence, essential oil and the like in a system and an antibacterial agent into a solvent to form a stable and transparent solution, improve the storage stability of the bromhidrosis spray, but also can effectively dissolve secretion generating the bromhidrosis, is easy to decompose without residue, and can improve the bromhidrosis removing capability of the bromhidrosis spray. Secondly, hydantoin is selected as a bactericide which can react with water to form a chlorine-containing compound, and triclosan is used as an antibacterial agent, so that the hydantoin and the antibacterial agent have synergistic effects, have killing and inhibiting effects on gram-positive bacteria, gram-negative bacteria, yeast and viruses, and can inhibit bacterial decomposition, sweat secretion and toxin metabolism catalysis; the bromhidrosis can kill bacteria and fungi, block the living environment of bacteria, thoroughly eliminate bromhidrosis and further improve the effect of treating bromhidrosis.
The second aspect of the invention provides a preparation method of a body odor spray containing Australia tea tree essential oil, which comprises the following steps:
(1) completely decomposing water and chelate to be transparent to obtain a mixed solution 1;
(2) mixing and stirring the essential oil, the emulsifier, the ethanol and the bactericide until the mixture is transparent to obtain a mixed solution 2;
(3) and adding the mixed solution 2 into the mixed solution 1, stirring until the mixed solution is transparent, finally adding the bactericide, and stirring until the mixed solution is transparent.
It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.
In addition, the raw materials used are commercially available from national chemical reagents, unless otherwise specified.
Examples
In order to better understand the above technical solutions, the following detailed descriptions will be provided with reference to specific embodiments. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention. In addition, the raw materials are commercially available and the extraction methods of the extract are all conventional extraction methods, if not otherwise specified.
Example 1
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 70.5 parts of water, 1 part of essential oil, 3 parts of emulsifier, 25 parts of ethanol, 0.2 part of antibacterial agent, 0.1 part of chelate, 0.1 part of bactericide and 0.1 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australia tea tree essential oil comprises the following steps:
(1) completely dissolving water and chelate till the solution is transparent to obtain a mixed solution 1;
(2) mixing and stirring the essential oil, the emulsifier, the ethanol and the bactericide until the mixture is transparent to obtain a mixed solution 2;
(3) and adding the mixed solution 2 into the mixed solution 1, stirring until the mixed solution is transparent, finally adding the bactericide, and stirring until the mixed solution is transparent.
Example 2
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 60 parts of water, 0.5 part of essential oil, 2 parts of emulsifier, 10 parts of ethanol, 0.05 part of antibacterial agent, 0.05 part of chelate, 0.05 part of bactericide and 0.05 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Example 3
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 80 parts of water, 2 parts of essential oil, 5 parts of emulsifier, 40 parts of ethanol, 0.3 part of antibacterial agent, 0.2 part of chelate, 0.2 part of bactericide and 0.2 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Example 4
Provides a bromhidrosis spray, which comprises the following preparation raw materials in parts by weight: 70.5 parts of water, 3 parts of emulsifier, 25 parts of ethanol, 0.2 part of antibacterial agent, 0.1 part of chelate, 0.1 part of bactericide and 0.1 part of essence.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Example 5
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 70.5 parts of water, 1 part of essential oil, 3 parts of emulsifier, 25 parts of ethanol, 0.1 part of chelate, 0.1 part of bactericide and 0.1 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Example 6
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 70.5 parts of water, 1 part of essential oil, 3 parts of emulsifier, 25 parts of ethanol, 0.2 part of antibacterial agent, 0.1 part of chelate and 0.1 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The emulsifier is a nonionic surfactant.
The nonionic surfactant is hydrogenated castor oil.
The hydrogenated castor oil is commercially available from Xiamen, Li Lai, Inc. under the type PEG-40.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Example 7
The body odor spray containing the Australia tea tree essential oil is provided, and the body odor spray comprises the following preparation raw materials in parts by weight: 70.5 parts of water, 1 part of essential oil, 25 parts of ethanol, 0.2 part of antibacterial agent, 0.1 part of chelate, 0.1 part of bactericide and 0.1 part of essence.
The essential oil is tea tree essential oil.
The tea tree essential oil is Australia tea tree essential oil which can be obtained commercially, and the manufacturer is Guangzhou Cheng Ji ya Biotechnology Co.
The antimicrobial agent was triclosan, commercially available from Xiamen, Li Ltd, model DP-300 (Yujichun).
The chelate is EDTA-2Na, commercially available, and is available from Xiamen, Li Ltd.
The bactericide is hydantoin and is commercially available, and the manufacturer is Xiamen, Li, Inc., and is the trade name Jialan Dan.
The essence is jasmine essence, can be obtained commercially, and is produced by Allen essence and spice Co.Ltd, and the brand is PD-164A.
The preparation method of the body odor spray containing the Australian tea tree essential oil is the same as that of the example 1.
Evaluation of Performance
The body odor spray containing the Australian tea tree essential oil obtained in examples 1 to 7 was subjected to clinical tests, and the results were as follows:
1. subject selection: selecting 140 patients with bromhidrosis;
2. grouping design: all patients were randomly divided into 7 groups, and 20 patients each had no significant difference in age, disease condition, etc. and were comparable.
3. The using method comprises the following steps: the experimental groups 1-7 directly sprayed the medicine to the armpit three times a day, and 30 days in total.
4. Criteria for judging therapeutic effects
And (3) curing: the bromhidrosis symptom of the patient disappears, and the body surface returns to normal;
the method has the following advantages: the symptoms of the bromhidrosis of the patient are gradually relieved or disappear;
and (4) invalidation: the symptoms of bromhidrosis are not improved;
total effective rate is (number of cure cases + number of effective cases)/number of cases.
5. The results are shown in Table 1
TABLE 1 therapeutic results
Figure BDA0002422759720000121
The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims (10)

1. The body odor spray containing Australian tea tree essential oil is characterized by at least comprising the following preparation raw materials in parts by weight: 60-80 parts of water, 0.5-2 parts of essential oil, 2-5 parts of emulsifier, 10-40 parts of ethanol, 0.05-0.3 part of antibacterial agent, 0.05-0.2 part of chelate, 0.05-0.2 part of bactericide and 0.05-0.2 part of essence.
2. The body odor spray containing Australian tea tree essential oil according to claim 1, wherein the essence is a floral essence.
3. The body odor spray containing Australian tea tree essential oil according to claim 2, wherein the floral essence is one or more selected from rose essence, jasmine essence, clove essence, sunflower essence, orange flower essence, gardenia essence and lavender essence.
4. The body odor spray containing Australian tea Tree essential oil according to claim 1, wherein the emulsifier is a nonionic surfactant.
5. The body odor spray containing Australian tea tree essential oil according to claim 4, wherein the nonionic surfactant is selected from one or more of long-chain fatty alcohol-polyoxyethylene ether, castor oil-polyoxyethylene ether, laurylamine-polyoxyethylene ether and hydrogenated castor oil.
6. The body odor spray containing Australian tea Tree essential oil according to claim 4, wherein the nonionic surfactant is hydrogenated castor oil.
7. The body odor spray containing Australian tea Tree essential oil according to claim 1, wherein the antibacterial agent is selected from one or more of zinc isooctanoate, zinc undecylenate, undecylenic acid monoethanolamide, and triclosan.
8. The body odor spray containing Australian tea tree essential oil according to claim 1, wherein the chelate is one or more selected from the group consisting of ethylenediamine tetramethylene phosphate, aminotrimethylene phosphonic acid, citric acid, gluconic acid, iminodiacetic acid, EDTA-2 Na.
9. The body odor spray containing Australian tea tree essential oil as claimed in claim 1, wherein the bactericide is one or more selected from phenoxyethanol, ethylhexyl glycerol, nano silver powder, cationic polyacrylamide and hydantoin.
10. The method for preparing a body odor spray containing Australian tea tree essential oil according to any one of claims 1 to 9, wherein the preparation method comprises the following steps:
(1) completely dissolving water and chelate till the solution is transparent to obtain a mixed solution 1;
(2) mixing and stirring the essential oil, the emulsifier, the ethanol and the bactericide until the mixture is transparent to obtain a mixed solution 2;
(3) and adding the mixed solution 2 into the mixed solution 1, stirring until the mixed solution is transparent, finally adding the bactericide, and stirring until the mixed solution is transparent.
CN202010210911.2A 2020-03-24 2020-03-24 Body odor spray containing Australian tea tree essential oil and preparation method thereof Withdrawn CN111228156A (en)

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Application publication date: 20200605