CN1046441A - The mosquito-repellent that contains crude vegetal - Google Patents

The mosquito-repellent that contains crude vegetal Download PDF

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Publication number
CN1046441A
CN1046441A CN90104414A CN90104414A CN1046441A CN 1046441 A CN1046441 A CN 1046441A CN 90104414 A CN90104414 A CN 90104414A CN 90104414 A CN90104414 A CN 90104414A CN 1046441 A CN1046441 A CN 1046441A
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CN
China
Prior art keywords
oil
mosquito
repellent
kapur
glycerine
Prior art date
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Pending
Application number
CN90104414A
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Chinese (zh)
Inventor
夏开元
郑金水
朗富和
黄明达
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INST OF BEIJING DONGFENG PHARMACEUTICAL FACTORY
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INST OF BEIJING DONGFENG PHARMACEUTICAL FACTORY
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Priority to CN90104414A priority Critical patent/CN1046441A/en
Publication of CN1046441A publication Critical patent/CN1046441A/en
Pending legal-status Critical Current

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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A kind of mosquito that contains crude vegetal drives agent, it is characterized in that this repellant contains: Litsea cubeba oil 20-100 part, eucalyptus oil 10-50 part, Blumea oil 10-50 part, peppermint oil 10-50 part, essence 10-50 part, medical ethanol 600-800 part, glycerine 50-100 part, said here umber is volume parts except that kapur is parts by weight.

Description

The mosquito-repellent that contains crude vegetal
The present invention relates to a kind of mosquito-repellent that contains crude vegetal, particularly relate to a kind of mosquito-repellent that contains cubeb litsen tree wet goods vegetable oil.
The mosquito-repellent of current domestic and international employing generally all contains chemical synthetic drug, and various countries are synthetic to have reached tens thousand of kinds with proof mosquito repellent compound.When but these compounds reach finite concentration in air, will produce some bad harm to human body, especially long-term the use can the toxigenicity cumulative effect.After entering the eighties,, in the chemical repellant of development, carried out the excavation of natural plants repellant along with the influence that the whole world " goes back to nature ".The chrysanthemum ester class repellant that in these years is widely used at home and abroad is though also natural component scope that belongs to finds that at present its long-term use also has certain harmful effect to human body more.And along with mosquito to its chemical sproof continuous enhancing, mosquito persister quantity also increases rapidly.
The object of the present invention is to provide a kind of mosquito-repellent that contains crude vegetal, to overcome the bad harm that the mankind is produced with the synthetic mosquito-repellent of chemical method.
The used natural material of mosquito-repellent of the present invention mainly contains eucalyptus oil, Litsea cubeba oil, Blumea oil, peppermint oil, kapur.These several natural materials all have commercially available, and its raw material sources are very abundant at home.Not seeing from ancient times to the present has it to be applied to the report of mosquito-repellent aspect.
Mosquito-repellent of the present invention is made up of eucalyptus oil, 20-100 part Litsea cubeba oil, 10-50 part Blumea oil, 10-50 part peppermint oil, 5-10 part kapur, 10-50 part essence, 600-800 part medical ethanol, 5-100 part glycerine and the deionized water of 10-50 part, and said here " umber " all refers to volume parts except that kapur is parts by weight.
In mosquito-repellent of the present invention, Litsea cubeba oil, property, Xin Wen, its 5% aqueous solution can kill culex pipiens pallens larvae, and finish or tincture glycerine are embrocated in skin and can be kept away mosquito altogether.Allocate 20-100ml in every 1000ml culicifuge of the present invention, be preferably 50ml; Kapur, is applied to local very gently to sensorineural stimulation at property suffering, hardship, cold, and some pain relieving and gentle antisepsis are arranged.At external higher concentration bacteriostasis is arranged, can be used for neuralgia or anti-inflammatory.Allocate the 3-10g kapur in every 1000ml culicifuge of the present invention, be preferably 5g; Peppermint oil, property suffering, cold, topical application can be controlled headache, neuralgia, itch etc.Allocate 10-50ml in every 1000ml culicifuge of the present invention, be preferably 30ml; When containing ethanol 70-75% in the disinfectant, the most favourable for the infiltration of the cell membrane of bacterium, ethanol infiltrates cell, makes the protein in its protoplasm and the cell nucleus become irreversible curdled appearance, to reach the purpose of kill bacteria.Allocate medical ethanol (concentration is 70~75%) in every 1000ml culicifuge of the present invention into, 600-800ml is preferably 730ml.Eucalyptus oil, property suffering, hardship, cold have inhibitory action to Gram-positive bacteria, are commonly used for deodorant and neuralgia patient's antalgesic, and the effect that eliminating the phlegm is arranged, relieving asthma.Investigation according to area, Sichuan anophelifuge among the people smears the back of the hand last 2 hour of no bite by mosquitos with eucalyptus oil.Blumea oil, property suffering, hardship, temperature can be used for indoor sterilization, and various pathomycetes are all had antibacterial and killing action, and mosquitos and flies is had repellent action.Go into 10-50ml in every 1000ml culicifuge of the present invention, be preferably 30ml.
The preparation method of mosquito-repellent of the present invention is:
1. 3-10 part kapur is dissolved in 600-800 part medical ethanol, under stirring respectively with 10-50 part eucalyptus oil, 20-100 part Litsea cubeba oil, 10-50 part Blumea oil, 10-50 part peppermint oil, 10-50 part essence, 50-100 part glycerine adds, fully add deionized water to 1000 part behind the mixing, stir.Here said umber is except that kapur is parts by weight, and all the other are volume parts.
2. above-mentioned finished product is put into refrigerator cold-storage (± 5 ℃) and stored 1~2 month, make it ripe.
3. the product of maturation is filtered, remove insoluble matter and impurity, make it to carry out packing after limpid and be finished product.
With horn method mosquito-repellent of the present invention is done toxicological test, test method is to be the mouse (Kunming mouse of female, male two kinds of sexes of 18-22 gram with body weight, provide by Nat'l Pharmaceutical ﹠ Biological Products Control Institute) each 20, respectively be divided into four dosage groups at random, every group 5, tried the agent amount and be 44,10.0,21.5, the 46.4g/kg body weight.Stopped eating 16 hours before irritating stomach, observe poisoning symptom and the death condition of mouse behind the filling stomach, and observed 14 days.
The result:
Poisoning symptom: irritated behind the stomach about 30 minutes, animal occurs walking haltingly, throws oneself on the ground, has difficulty in breathing, goes into a coma, until death.
Male mice per os LD50 is 19,6g/kgBW, 95% fiducial limit, 11.8~32.6g/kg.
Female mice per os LD50>20g/kgBW.
Press the acute toxicity grading criteria of Deichman and Gerarde and judge that mosquito-repellent of the present invention belongs to basic non-toxic type material.Making the Culex pipiens pallens repellent through the city health and epidemic prevention station personnel selection method that lures detects, the result shows: smear behind the medicine and bite by mosquitos (control group is bitten 9 person-times in 20 minutes) do not occur in 4 hours, the relevant requirements that meets sanitary standard, its repelling effect significantly are better than like product (it is particularly outstanding that chrysanthemum ester constituents is produced its effect of chemical sproof mosquito).And the 4th hospital clinical checking through Beijing, culicifuge of the present invention is after indoor spraying, it prevents that the bite by mosquitos total effective rate from being 100%, and culicifuge of the present invention also have concurrently antipruritic, the effect of anti-inflammatory, it is efficient to be 100%.
The following examples are to further specify of the present invention, rather than limitation of the invention.
Embodiment 1
The 3g kapur is dissolved in the 600ml medical ethanol, under stirring, respectively 10ml eucalyptus oil, 100ml Litsea cubeba oil, 50ml Blumea oil, 50ml peppermint oil, 10ml essence, 100ml glycerine are added, fully add deionized water 80ml behind the mixing, stir, then this mixture is put into refrigerator and cooled and hidden (± 5 ℃), store 1 month, make it ripe.The product of maturation is filtered, remove insoluble matter and impurity, make it to carry out packing after limpid.
Embodiment 2
The preparation method is with example 1, and used component and consumption are as follows:
10g kapur, 800ml medical ethanol, 50ml eucalyptus oil, 20ml Litsea cubeba oil, 10ml Blumea oil, 10ml peppermint oil, 50ml essence, 50ml glycerine, 10ml deionized water.
Embodiment 3
The preparation method is with example 1, and used component and consumption are as follows:
4g kapur, 700ml medical ethanol, 20ml eucalyptus oil, 40ml Litsea cubeba oil, 30ml Blumea oil, 20ml peppermint oil, 40ml essence, 70ml glycerine, 80ml deionized water.

Claims (3)

1, a kind of mosquito-repellent that contains crude vegetal, it is characterized in that this repellant contains: Litsea cubeba oil 20-100 part, eucalyptus oil 10-50 part, Blumea oil 10-50 part, peppermint oil 10-50 part, essence 10-50 part, medical ethanol 600-800 part, glycerine 50-100 part, deionized water 0-290 part, kapur 5-10 part, it is that weight is volume parts especially that said here umber removes kapur.
2,, it is characterized in that the medical ethanol determining alcohol is 70-75% according to the said mosquito-repellent of claim 1.
3, the preparation method of the described mosquito-repellent of claim 1 is characterized in that:
3-10 part kapur is dissolved in 600-800 part medical ethanol, under stirring, respectively 10-50 part eucalyptus oil, 20-100 part Litsea cubeba oil, 10-50 part Blumea oil, 10-50 part peppermint oil, 10-50 part essence, 50-100 part glycerine are added, fully add deionized water to 1000 part behind the mixing, (said here umber is except that kapur is parts by weight, all the other components are volume parts), stir; Above-mentioned finished product is put into refrigerator and cooled hide (± 5 ℃) storage 1~2 month, make it ripe; The product of maturation is filtered, remove insoluble matter and impurity, make it to carry out packing after limpid.
CN90104414A 1990-06-16 1990-06-16 The mosquito-repellent that contains crude vegetal Pending CN1046441A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN90104414A CN1046441A (en) 1990-06-16 1990-06-16 The mosquito-repellent that contains crude vegetal

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Application Number Priority Date Filing Date Title
CN90104414A CN1046441A (en) 1990-06-16 1990-06-16 The mosquito-repellent that contains crude vegetal

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CN1046441A true CN1046441A (en) 1990-10-31

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432051A (en) * 2013-06-29 2013-12-11 安徽榄菊日用制品有限公司 Mosquito repelling and itching relieving toilet water and preparation method thereof
CN103621481A (en) * 2013-12-05 2014-03-12 广东省昆虫研究所 Indoor evaluating method for repellant effects of pest repellents
CN104054754A (en) * 2014-07-01 2014-09-24 广州中医药大学 Mikania micrantha mosquito repellent
CN105230685A (en) * 2015-11-06 2016-01-13 西南大学 Herbaceous plant essential oil composition with mosquito repelling effect
CN106265168A (en) * 2016-10-11 2017-01-04 济南大学 A kind of preparation method of natural composite plant mosquito-driving liquid antibacterial, antipruritic
CN106265352A (en) * 2016-09-22 2017-01-04 佛山慧创正元新材料科技有限公司 A kind of natural mosquito repellent for infant spraying
CN107897217A (en) * 2017-12-20 2018-04-13 五邑大学 A kind of natural volatile mosquito driving and killing agent of plant source property and preparation method thereof
CN109157564A (en) * 2018-09-20 2019-01-08 翟顺才 A kind of health-care paste of bacterio static itching-relieving
CN109864074A (en) * 2019-03-28 2019-06-11 姚志民 A kind of mosquito dispersing composition and its preparation method and application

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432051A (en) * 2013-06-29 2013-12-11 安徽榄菊日用制品有限公司 Mosquito repelling and itching relieving toilet water and preparation method thereof
CN103621481A (en) * 2013-12-05 2014-03-12 广东省昆虫研究所 Indoor evaluating method for repellant effects of pest repellents
CN103621481B (en) * 2013-12-05 2015-07-01 广东省昆虫研究所 Indoor evaluating method for repellant effects of pest repellents
CN104054754A (en) * 2014-07-01 2014-09-24 广州中医药大学 Mikania micrantha mosquito repellent
CN105230685A (en) * 2015-11-06 2016-01-13 西南大学 Herbaceous plant essential oil composition with mosquito repelling effect
CN105230685B (en) * 2015-11-06 2018-04-03 西南大学 Herbaceous plant essential oil composition with repelling effect
CN106265352A (en) * 2016-09-22 2017-01-04 佛山慧创正元新材料科技有限公司 A kind of natural mosquito repellent for infant spraying
CN106265168A (en) * 2016-10-11 2017-01-04 济南大学 A kind of preparation method of natural composite plant mosquito-driving liquid antibacterial, antipruritic
CN107897217A (en) * 2017-12-20 2018-04-13 五邑大学 A kind of natural volatile mosquito driving and killing agent of plant source property and preparation method thereof
CN109157564A (en) * 2018-09-20 2019-01-08 翟顺才 A kind of health-care paste of bacterio static itching-relieving
CN109864074A (en) * 2019-03-28 2019-06-11 姚志民 A kind of mosquito dispersing composition and its preparation method and application

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