CN111201017A - 制备富含氘的n-乙酰基半胱氨酸酰胺(d-naca)和(2r,2r′)-3,3′-二硫烷二基双(2-乙酰氨基丙酰胺)(dinaca)及使用d-naca和dinaca治疗涉及氧化应激的疾病的方法 - Google Patents

制备富含氘的n-乙酰基半胱氨酸酰胺(d-naca)和(2r,2r′)-3,3′-二硫烷二基双(2-乙酰氨基丙酰胺)(dinaca)及使用d-naca和dinaca治疗涉及氧化应激的疾病的方法 Download PDF

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CN111201017A
CN111201017A CN201880047207.0A CN201880047207A CN111201017A CN 111201017 A CN111201017 A CN 111201017A CN 201880047207 A CN201880047207 A CN 201880047207A CN 111201017 A CN111201017 A CN 111201017A
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mol
disulfanediylbis
acetamidopropionamide
pharmaceutical composition
dinaca
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Chinese (zh)
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G·M·沃尔
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Brighton Biotech Inc
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Brighton Biotech Inc
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CN201880047207.0A 2017-11-09 2018-11-06 制备富含氘的n-乙酰基半胱氨酸酰胺(d-naca)和(2r,2r′)-3,3′-二硫烷二基双(2-乙酰氨基丙酰胺)(dinaca)及使用d-naca和dinaca治疗涉及氧化应激的疾病的方法 Pending CN111201017A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762583984P 2017-11-09 2017-11-09
US62/583984 2017-11-09
US201762587246P 2017-11-16 2017-11-16
US62/587246 2017-11-16
US16/180984 2018-11-05
US16/180,984 US20190135741A1 (en) 2017-11-09 2018-11-05 Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress
PCT/US2018/059446 WO2019094383A1 (en) 2017-11-09 2018-11-06 Methods of making deuterium-enriched n-acetylcysteine amide (d-naca) and (2r,2r')-3,3' -disulfanediyl bis(2-acetamidopropanamide) (dinaca) and using d-naca and dinaca to treat diseases involving oxidative stress

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CN111201017A true CN111201017A (zh) 2020-05-26

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US (2) US20190135741A1 (https=)
EP (1) EP3534890A4 (https=)
JP (1) JP2021502323A (https=)
KR (2) KR20220016304A (https=)
CN (1) CN111201017A (https=)
AU (3) AU2018365900B2 (https=)
CA (2) CA3046363C (https=)
RU (1) RU2019126848A (https=)
WO (1) WO2019094383A1 (https=)

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Application publication date: 20200526