CN111035686A - Plant source compound Chinese medicine smelling agent and preparation method thereof - Google Patents

Abstract

The invention relates to a plant source compound Chinese medicine smelling agent and a preparation method thereof, which is characterized in that: is prepared from high-quality herbivore, evodia fruit, rhubarb, dahurian angelica root, scutellaria root, Chuan-xiong rhizome and gleditsia sinensis through baking, pulverizing to 200 meshes, mixing with borneol, sterilizing, metering and loading. The invention is effective to migraine, coma, rhinitis, common cold, hypertension, heart disease, cerebral apoplexy, periodontitis, decayed tooth, gastrospasm, hiccup, prostatitis, periodontitis, decayed tooth and the like.

Description

Plant source compound Chinese medicine smelling agent and preparation method thereof

The invention belongs to the technical field of plant-derived traditional Chinese medicines, and particularly relates to a plant-derived compound traditional Chinese medicine smelling agent and a preparation method thereof.

With the improvement of economic conditions, people have higher and higher intake of food and medicines, especially traditional Chinese medicine preparations, most of the medicines are bitter, and the people do not like to take the medicines by the current young people.

In ancient Chinese medicine, there are theory and medicine of 'restoring consciousness and inducing resuscitation', the medicine powder is inhaled into nostrils through nasal cavity, enters lung, then enters blood through alveolus, participates in the whole body circulation, and plays roles of harmonizing yin and yang, dredging channels and collaterals, strengthening body resistance and eliminating evil, etc.

Modern medical research shows that: the mucous membrane of the nasal cavity and the covered micro cilia provide more absorption sites, and the thin and porous mucous membrane is rich in blood vessels and blood flow and the medicine is quickly absorbed and directly enters the systemic blood circulation. The olfactory region mucous membrane venous blood flows back into the superior sagittal sinus, and the absorbed medicine directly enters the internal jugular vein and does not pass through the liver circulation, thereby avoiding the first pass effect of oral administration. Because the nasal cavity mucous membrane hydrolase is less and the activity is lower than that of the gastrointestinal tract, the medicine which is easily degraded and destroyed by the digestive enzyme of the gastrointestinal tract is better to be administrated through the nasal cavity. In addition, some medicines with large polarity and difficult absorption by gastrointestinal tract, protein polypeptide with large molecular weight and easy degradation by digestive enzyme, etc. can be absorbed better on nasal mucosa by the absorption enhancer in the dosage form.

Therefore, the drug is used in the nasal cavity, and the drug which is absorbed through the nasal mucosa to exert the systemic therapeutic effect plays a unique role in preventing and treating diseases.

The invention relates to a plant source compound Chinese medicine smelling agent and a preparation method thereof, which is characterized in that: is prepared from high-quality herbivore, evodia fruit, rhubarb, dahurian angelica root, scutellaria root, Chuan-xiong rhizome and gleditsia sinensis through baking, pulverizing to 200 meshes, mixing with borneol, sterilizing, metering and loading.

The plant source compound Chinese medicine smelling agent adopts the following Chinese medicines:

1. all-grass of common Meadowrue

The leaf-eating grass is a novel excellent variety obtained by somatic hybridization through a variety selection test for years by a special subject group of professor of Bai Lu mountain, namely Beijing Jun Xin quan Sheng environmental science and technology research institute, and finally selecting a Rumex K-1 plant as a mother line and wild Rumex japonicus leaf of Mishan of Heilongjiang as a father line.

The leaf eating grass is rich in nutrition, the protein content is more than 23 percent, the content of 18 amino acids is more than 27 percent, the vitamin content, the beneficial mineral content, the selenium content, the SOD content, the potassium content, the isoflavone content, the β carotene content and the VC content are high, particularly the potassium content reaches 2805mg/100g, the total ascorbic acid VC content is 608mg/100g, the calcium content is 683mg/100g, and the total flavone content is 24.7mg/100g, which is the highest content value of the hybrid plants so far.

The EYECAO contains high contents of protein, selenium, molybdenum, SOD, β -carotene, emodin, isoflavone and other antioxidant substances, has unique effects on inhibiting and treating cancers, and particularly has obvious effects on gastric cancer, intestinal cancer, breast cancer, esophageal cancer and lung cancer.

2. Evodia rutaecarpa

Is immature fruit of Rutaceae plants including fructus evodiae, herba Boeae and fructus evodiae, and has pungent, bitter and hot taste; has little toxicity. It enters liver, spleen, stomach and kidney meridians.

The main treatment is as follows: headache due to syncope, vomiting and diarrhea due to chills, abdominal pain during menstruation, diarrhea before dawn, hypertension, tinea pedis, hernia, aphtha, ulcer, toothache, eczema, and impetigo.

3. Radix et rhizoma Rhei

Nature and taste: bitter and cold. It enters spleen, stomach, large intestine, liver and pericardium meridians.

Accumulation attacking and stagnation removing: the flavor is bitter, the qi is cold, the nature is deep and descending, the force is strong and good, the medicine can directly go to the lower jiao, and the medicine is longer than the lower jiao. Entering yangming, it can wash out excess heat accumulation in stomach and intestine. Cold-heat, warm disease and heat accumulation in the middle. Cooling blood and removing toxicity: the bitter taste and the cold-qi enter the qi system and also divide the qi system, which has the effect of purging heat and cooling blood, so the recording of Zhongzhao Zhongzhuoxi recorded in medicine is recorded as follows: da Huang is the essential herb for treating eye pain because it enters blood system and tends to descend and clear heat in the upper part. It is also good at relieving sore and ulcer heat-toxicity, especially for treating toxicity. It can lower stomach heat and induce stomach qi to go downward, so it is good at stopping hematemesis and epistaxis. Blood circulation promoting and stasis removing book of materia medica easy to read says: rhubarb, radix et rhizoma Rhei, bitter in taste and cold in nature, enters Taiyin spleen and Jueyin liver meridian. Purging heat and removing blood stasis, resolving the congestion and opening obstruction. Unblock meridians and collaterals to break the crux. Drastic action, old herb can cause new herb, remove blood stasis and generate new blood.

4. Root of Dahurian Angelica

Nature and taste: warm in nature, pungent, fragrant in smell and slightly bitter.

The functional indications are as follows: expelling wind-damp, promoting blood circulation, expelling pus, promoting granulation, and relieving pain. Can be used for treating headache, toothache, nasosinusitis, hemorrhoid, leucorrhea with red and white discharge, carbuncle, cellulitis, pyocutaneous disease, and skin pruritus.

5. Radix Scutellariae

Bitter taste, mild smell, cold nature, ascending and descending, and no toxicity. Enter lung meridian and large intestine.

This is said: all the heat jaundice, intestine diarrhea and dysentery, diuresis, bleeding retention, sore and deep-rooted carbuncle, fire ulcer.

Respectively recording the records: treating phlegm-heat in stomach, lower abdominal colic, food stagnation, small intestine, female blood stasis, stranguria, and infantile abdominal pain.

The right is given as: treating heat-toxin bone steaming, alternating cold and heat, gastrointestinal disorder, qi stagnation, five stranguria, smooth, joint vexation, fever and thirst.

6. Rhizoma Ligustici Chuanxiong

Nature and taste: warm and pungent in flavor, it enters liver, gallbladder and pericardium meridians.

The functions are as follows: promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain. Can be used for treating thoracic obstruction, cardialgia, pricking pain in chest and hypochondrium, traumatic swelling and pain, headache, and rheumatalgia.

7. Pig tooth soap

Nature and taste: pungent, salty, warm and small toxicity enter lung and large intestine meridians.

The main treatment is as follows: eliminating phlegm for resuscitation, resolving hard mass and relieving swelling, and can be used for treating apoplexy, trismus, coma, epilepsy, excessive phlegm, obstruction of orifices, pharyngitis, phlegm stagnation, intractable phlegm cough, asthma, difficulty in expectoration, constipation, and carbuncle and swelling.

8. Borneol (borneol)

Borneol is slightly cold in nature and pungent and bitter in taste, and has the effects of inducing resuscitation, refreshing mind, clearing heat and relieving pain.

The invention relates to a plant source compound Chinese medicine smelling agent and a preparation method thereof, which is characterized in that: is prepared from high-quality herbivore, evodia fruit, rhubarb, dahurian angelica root, scutellaria root, Chuan-xiong rhizome and gleditsia sinensis through baking, pulverizing to 200 meshes, mixing with borneol, sterilizing, metering and loading.

The invention is effective to migraine, coma, rhinitis, common cold, hypertension, heart disease, cerebral apoplexy, periodontitis, decayed tooth, gastrospasm, hiccup, prostatitis, periodontitis, decayed tooth and the like.

The invention relates to a plant source compound Chinese medicine smelling agent and a preparation method thereof, which are characterized in that the plant source compound Chinese medicine smelling agent can be produced by two different processes.

The first method comprises the following steps: low temperature freeze drying process is adopted.

20-30% of high-quality, measured and fresh leaf-eating grass, 30-20% of fructus evodiae, 15-10% of rheum officinale, 5-10% of radix angelicae, 10-15% of scutellaria baicalensis, 15-10% of ligusticum wallichii and 1-4% of fructus gleditsiae, and the selected traditional Chinese medicines are cut into threads and put into a vacuum environment at the temperature of-40 ℃ for dehydration for 16-24 hours, wherein the dehydration rate reaches 92%. Then crushing, sterilizing, metering, packaging and crushing to 200 meshes, uniformly mixing with 4-1% of borneol, sterilizing, metering and filling to obtain the borneol powder.

And the second method comprises the following steps: the conventional process is adopted.

And (3) preparing a high-quality dry product: 20-30% of common leafflower herb, 30-20% of fructus evodiae, 15-10% of rheum officinale, 5-10% of radix angelicae, 10-15% of scutellaria baicalensis, 15-10% of ligusticum wallichii and 1-4% of fructus gleditsiae, respectively drying at the temperature of 45 ℃, crushing to 200 meshes, uniformly mixing with 4-1% of borneol, sterilizing, metering and filling to obtain the traditional Chinese medicine.

The invention relates to a plant source compound Chinese medicine smelling agent and a preparation method thereof, which is characterized in that: raw materials of the leaf-eating grass need to adopt professor Bai Green mountain of Beijing Junxin spring flourishing environmental science and technology research institute, lead special subject groups undergo seed selection tests for several years, and finally, a Rumex K-1 plant is selected as a mother line, wild Rumex japonicus Houtt of Mishan of Heilongjiang is selected as a father line, and a novel excellent variety is obtained through somatic cell hybridization.

The present technology is further illustrated by the following examples.

Embodiment 1, a plant source compound Chinese medicine smelling agent and preparation thereof

Group (c): 20 g of common leafflower herb, 30 g of fructus evodiae, 15 g of rhubarb, 5 g of angelica dahurica, 10 g of radix scutellariae, 15 g of rhizoma ligustici wallichii, 1 g of fructus gleditsiae and 4 g of borneol.

Preparation: high-quality dried products, namely, 20 g of common leafflower herb, 30 g of evodia, 15 g of rhubarb, 5 g of angelica dahurica, 10 g of baical skullcap root, 15 g of Szechuan lovage rhizome and 1 g of fructus gleditsiae, are crushed into 200 meshes, are uniformly mixed with 4 g of borneol, and are subjected to sterilization, metering and filling to obtain the traditional Chinese medicine.

Zhang XX, female, 45 years old, Beijing, migraine two years old, many people seek medical ineffectiveness, use smelling agent, twice a day, fully recover after one month.

Embodiment 2, a plant source compound Chinese medicine smelling agent and preparation thereof

Group (c): 30 g of common leafflower herb, 20 g of fructus evodiae, 10 g of rhubarb, 10 g of angelica dahurica, 15 g of radix scutellariae, 10 g of rhizoma ligustici wallichii, 4 g of fructus gleditsiae and 1 g of borneol.

Preparation: drying high-quality dried products of 30 g of common leafflower herb, 20 g of evodia rutaecarpa, 10 g of rhubarb, 10 g of angelica dahurica, 15 g of scutellaria baicalensis, 10 g of ligusticum wallichii and 4 g of fructus gleditsiae at the temperature of 45 ℃, respectively crushing into 200 meshes, uniformly mixing with 1 g of borneol, sterilizing, metering and filling to obtain the traditional Chinese medicine.

Miao XX, male, 19 years old and taiyuan people, rhinitis affects the school for many years and seriously, and the rhinitis is cured three times a day and two months later by using the inhalant.

Embodiment 3, a plant-derived compound Chinese medicinal inhalant and preparation thereof

Group (c): 25 g of common leafflower herb, 25 g of fructus evodiae, 12 g of rhubarb, 8 g of angelica dahurica, 12 g of radix scutellariae, 13 g of rhizoma ligustici wallichii, 3 g of fructus gleditsiae and 2 g of borneol.

Preparation: the preparation method comprises the steps of cutting 25 g of high-quality, measured and fresh leaf-eating grass, 25 g of fructus evodiae, 12 g of rheum officinale, 8 g of radix angelicae, 12 g of scutellaria baicalensis, 13 g of ligusticum wallichii and 3 g of fructus gleditsiae into threads, and placing the threads in a vacuum environment at the temperature of-40 ℃ for dehydration for 16-24 hours, wherein the dehydration rate reaches 92%. Then crushing, sterilizing, metering, packaging and crushing to 200 meshes, mixing with 2 g of borneol uniformly, sterilizing, metering and filling to obtain the borneol powder.

The beam XX, women, 50 years old and people in Taiyuan city, usually have heart region pain and blood pressure higher by 95-145 mmHg, and the blood pressure tends to be normal twice a day and half a year later by using the inhalant.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (5)

1. A plant source compound Chinese medicine smelling agent and a preparation method thereof are characterized in that: is prepared from high-quality herbivore, evodia fruit, rhubarb, dahurian angelica root, scutellaria root, Chuan-xiong rhizome and gleditsia sinensis through baking, pulverizing to 200 meshes, mixing with borneol, sterilizing, metering and loading.

2. The plant-derived compound Chinese medicinal smelling agent and the preparation thereof according to claim 1, is characterized by comprising the following components in parts by weight:

3. the plant-derived compound Chinese medicinal smelling agent and the preparation thereof according to claim 1, characterized in that the plant-derived compound Chinese medicinal smelling agent can be produced by two different processes.

The first method comprises the following steps: low temperature freeze drying process is adopted.

20-30% of high-quality, measured and fresh leaf-eating grass, 30-20% of fructus evodiae, 15-10% of rheum officinale, 5-10% of radix angelicae, 10-15% of scutellaria baicalensis, 15-10% of ligusticum wallichii and 1-4% of fructus gleditsiae, and the selected traditional Chinese medicines are cut into threads and put into a vacuum environment at the temperature of-40 ℃ for dehydration for 16-24 hours, wherein the dehydration rate reaches 92%. Then crushing, sterilizing, metering, packaging and crushing to 200 meshes, uniformly mixing with 4-1% of borneol, sterilizing, metering and filling to obtain the borneol powder.

And the second method comprises the following steps: the conventional process is adopted.

And (3) preparing a high-quality dry product: 20-30% of common leafflower herb, 30-20% of fructus evodiae, 15-10% of rheum officinale, 5-10% of radix angelicae, 10-15% of scutellaria baicalensis, 15-10% of ligusticum wallichii and 1-4% of fructus gleditsiae, respectively drying at the temperature of 45 ℃, crushing to 200 meshes, uniformly mixing with 4-1% of borneol, sterilizing, metering and filling to obtain the traditional Chinese medicine.

4. The plant-derived compound Chinese medicinal smelling agent and the preparation thereof according to claim 1, characterized in that: raw materials of the leaf-eating grass need to adopt professor Bai Green mountain of Beijing Junxin spring flourishing environmental science and technology research institute, lead special subject groups undergo seed selection tests for several years, and finally, a Rumex K-1 plant is selected as a mother line, wild Rumex japonicus Houtt of Mishan of Heilongjiang is selected as a father line, and a novel excellent variety is obtained through somatic cell hybridization.

5. The product of the invention does not contain any preservative.