CN111760006A

CN111760006A - Medicine formula for treating liver cirrhosis

Info

Publication number: CN111760006A
Application number: CN202010811919.4A
Authority: CN
Inventors: 苏春芝
Original assignee: Hebei Provincial Hospital Of Traditional Chinese Medicine
Current assignee: Hebei Provincial Hospital Of Traditional Chinese Medicine
Priority date: 2020-08-13
Filing date: 2020-08-13
Publication date: 2020-10-13

Abstract

The invention discloses a pharmaceutical formula for treating liver cirrhosis, which comprises, by weight, 9-10g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9-12g of radix scutellariae, 9-12g of rhizoma coptidis, 12g of codonopsis pilosula, 10-12g of angelica sinensis, 10-12g of radix paeoniae alba, 10-12g of roasted turtle shell, 6-9g of mangnolia officinalis, 8-10g of fructus psoraleae, 10-12g of rhizoma atractylodis macrocephalae, 10-12g of poria cocos, 9g of radix glycyrrhizae preparata, 6g of ginger, 6g of Chinese date and 8-10g of radix ophiopogonis. The invention is suitable for treating liver cirrhosis, solves the problem of great side effect of the existing medicament for treating liver cirrhosis, and obviously improves the symptoms of patients with liver cirrhosis and the life quality through years of clinical application.

Description

Medicine formula for treating liver cirrhosis

Technical Field

The invention belongs to the technical field of formulas, and particularly relates to a medicine formula for treating liver cirrhosis.

Background

Liver cirrhosis (liver cirrhosis LC) refers to chronic progressive, diffuse and fibrotic lesions of the liver caused by various reasons, is one of the clinically common chronic digestive system diseases, and seriously harms the health and life safety of patients. The disease has slow onset and long course of disease, and the incidence rate of men is higher than that of women, and the disease is often seen in middle-aged and old men. If the treatment is not performed in time, complications such as upper gastrointestinal hemorrhage, hepatic encephalopathy, hepatorenal syndrome and the like can occur. The cirrhosis can be divided into a compensatory phase and a non-compensatory phase, the compensatory phase generally has evidence of hepatocyte synthesis dysfunction or portal hypertension (such as splenic hyperfunction and esophageal and gastric fundus varices) by imaging, biochemical or hematology examination, or the histology accords with the diagnosis of the cirrhosis, but has no serious complications such as esophageal and gastric fundus varices rupture bleeding, ascites or hepatic encephalopathy. The patients in the non-compensatory stage have serious complications such as esophageal and gastric variceal bleeding, hepatic encephalopathy, ascites and the like. Active treatment during the compensatory phase of cirrhosis, slowing down the progression to the decompensated phase or completely reversing it is currently an urgent task. The treatment measures for the liver cirrhosis in the clinical practice of western medicine are mainly the treatment of the cause and the symptom, and the basic treatment such as rest, diet and the like is emphasized. The drug treatment mainly comprises the functions of protecting liver cells, resisting fibrosis, resisting virus and the like. However, most of the treatment measures are to neglect the condition of the human body due to exogenous pathogenic factors, western medicines for protecting the liver and resisting viruses are applied reluctantly, although the condition is controlled sometimes, the liver is easily loaded, and the condition is caused to repeat and aggravate.

Disclosure of Invention

The invention aims to provide a medicine formula for treating liver cirrhosis,

in order to achieve the purpose, the technical scheme adopted by the invention is as follows:

the invention comprises 9-10g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9-12g of radix scutellariae, 9-12g of coptis chinensis, 12g of codonopsis pilosula, 10-12g of angelica sinensis, 10-12g of radix paeoniae alba, 10-12g of carapax amydae preparata, 6-9g of mangnolia officinalis, 8-10g of fructus psoraleae, 10-12g of rhizoma atractylodis macrocephalae, 10-12g of poria cocos, 9g of radix glycyrrhizae preparata, 6g of ginger, 6g of Chinese date and 8-10g of radix ophiopogonis.

The invention has the following advantages:

the invention is suitable for treating liver cirrhosis, solves the problem of great side effect of the existing medicament for treating liver cirrhosis, and obviously improves the symptoms of patients with liver cirrhosis and the life quality through years of clinical application.

Detailed Description

The present invention is further illustrated by the following examples, which are intended to be in a manner including, but not limited to, the following examples.

Example 1

The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. It should also be understood that various changes or modifications may be made by those skilled in the art after reading the above disclosure, and such equivalents may fall within the scope of the invention as defined by the appended claims.

Bupleurum root, radix bupleuri, a commonly used exterior-releasing drug, is bitter in flavor and slightly cold in nature, and enters liver and gallbladder meridians. Has the functions of harmonizing exterior and interior, soothing liver and invigorating yang. The radix bupleuri has the effects of relieving and allaying fever, soothing liver and relieving depression and lifting yang qi, can be used for treating cold injury pathogenic factors in shaoyang, mainly manifested by alternating chills and fever, fullness in chest and hypochondrium, bitter taste in mouth and dry throat, dizziness and the like, and can also be used for treating chest and hypochondrium distending pain, headache, irregular menstruation and dysmenorrheal caused by stagnation of liver qi, and the radix bupleuri can also regulate and regulate liver qi, sooth liver and relieve depression, is often used together with radix paeoniae alba and angelica sinensis and is used for treating liver depression and qi stagnation.

Rhizoma Pinelliae Preparata is prepared from rhizoma Pinelliae (processed with Alumen (aqueous potassium aluminum sulfate) by soaking in solution, and has effects of reducing toxicity and irritation, enhancing the effects of rhizoma Pinelliae in eliminating dampness and phlegm, lowering adverse qi, relieving vomit, relieving distension and relieving masses. It is indicated for cold drink of damp-phlegm manifested as vomiting, regurgitation, cough, dyspnea, profuse phlegm, fullness and distention in chest and diaphragm, phlegm syncope, headache, dizziness, insomnia, and external abscess and swelling.

Scutellaria baicalensis Georgi belongs to Labiatae, is bitter and cold in nature, and enters lung, gallbladder, spleen, large intestine and small intestine meridians. Has the effects of clearing heat, eliminating dampness, purging pathogenic fire, removing toxic substances, stopping bleeding, and preventing miscarriage. Can be used for treating damp-warm and summer-damp, chest distress, emesis, damp-heat distention and fullness, dysentery, and jaundice; cough due to lung heat, high fever and polydipsia; abscess, swelling and sore, etc. Unprocessed is indicated for clearing heat, purging and removing toxicity, stir-baked mostly for preventing abortion, stir-baked with wine for clearing heat from upper energizer, and stir-baked to charcoal for stopping bleeding.

Coptis root, rhizoma Coptidis clears heat and dampness, purges fire and detoxifies. Can be used for treating damp-heat distention, fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, coma, excessive heart-fire, vexation, insomnia, hematemesis, hemorrhage, conjunctival congestion, toothache, diabetes, carbuncle, furuncle, etc.; it is used externally to treat eczema, eczema and purulent ear canal. Huang Lian (Chinese goldthread) processed with wine is good at clearing heat in upper energizer. It can be used for treating conjunctival congestion and aphtha. Jiang Huang Lian can clear stomach, harmonize stomach and stop vomiting. Can be used for treating cold and heat accumulation, damp-heat obstruction, fullness and emesis. Yu Huang Lian soothes liver, harmonizes stomach and stops vomiting. Can be used for treating liver and stomach disharmony, emesis, and acid regurgitation.

Dang Gui is sweet, pungent and warm in nature, and enters liver, heart and spleen meridians. Therefore, the Chinese angelica powder is the first medicine for enriching blood, is suitable for symptoms of pale or sallow complexion, lassitude and hypodynamia, pale and lusterless lips and nails, light headedness, palpitation and insomnia and the like caused by heart-liver blood deficiency, has obvious stimulation effect on a mononuclear-macrophage system by Chinese angelica and extract sodium ferulate and Chinese angelica polysaccharide, and also has immune regulation and recovery effect on an organism with low immune function. Dang Gui is also known as an essential blood medicine for promoting the transformation of lymphocytes of healthy people.

Vinegar carapax Trionycis is the back of turtle of Trionychidae, and is usually made by scalding fresh carapax Trionycis with sand and quenching with vinegar. Salty in property and slightly cold in nature. It enters liver and kidney meridians. Has effects in nourishing yin, suppressing yang hyperactivity, relieving fever, removing dampness, softening and resolving hard mass. It is commonly indicated for fever due to yin deficiency, bone-steaming, fatigue-heat, hyperactivity of yang due to yin deficiency, dizziness, vertigo, amenorrhea, chronic malaria and malaria with malaria. According to modern pharmacological research, turtle shells can enhance immune function, enhance natural killer cell activity and enhance macrophage phagocytic function; can prevent cell mutation, and has anti-tumor effect.

Magnolia officinalis is a Magnoliaceae plant, pungent, bitter and warm in nature. It enters spleen, stomach, lung and large intestine meridians. Has the effects of eliminating dampness and phlegm, and descending qi and relieving fullness. It is commonly used for excess and stagnation in the middle energizer, gastric and spleen vomiting and diarrhea; food retention, qi stagnation, abdominal distension and constipation; phlegm-fluid retention cough and asthma. Modern pharmacological research believes that the magnolia bark decoction has an inhibiting effect on pneumococcus, diphtheria bacillus, hemolytic streptococcus, hay bacillus, staphylococcus aureus and the like, and can reduce blood pressure, and reflex causes respiratory excitation and heart rate acceleration during blood pressure reduction.

The fructus Psoraleae is dry mature fruit of Psoralea corylifolia of Leguminosae, pungent, bitter and warm in nature, and enters kidney and spleen meridians. Has the effects of warming kidney, supporting yang, absorbing qi, relieving asthma, warming spleen and checking diarrhea, and is used for dispelling pathogenic wind and removing ecchymoses for external use. It is commonly used for kidney yang deficiency, impotence, infertility, cold pain of waist and knees; seminal emission and spermatorrhea due to kidney deficiency, enuresis and frequent urination; spleen-kidney yang deficiency, morning diarrhea, etc. Modern pharmacological research shows that the fructus psoraleae has an estrogen-like effect, can strengthen vaginal keratosis and enhance uterine weight. Can expand coronary artery, excite heart, and increase heart power.

Atractylodis rhizoma is dry rhizome of Atractylodes macrocephala Koidz of Compositae, and is sweet, bitter and warm in nature, and enters spleen and stomach meridians. Has effects in invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, arresting sweating, and preventing miscarriage. It is commonly used for spleen deficiency with poor appetite, abdominal distention, loose stool, phlegm and fluid retention with dizziness, palpitation, edema, and leukorrhagia; spontaneous sweating due to qi deficiency; spleen deficiency and threatened abortion, etc. Modern pharmacological research shows that the decoction of white atractylodes rhizome can promote gastric emptying and small intestine propulsion of mice, prevent and treat experimental gastric ulcer and resist senility.

Poria is sweet, bland and neutral in nature, and enters heart, lung, spleen and kidney meridians. Has effects in promoting diuresis, eliminating dampness, invigorating spleen, and calming heart. It is commonly indicated for edema, oliguria, phlegm-fluid retention, dizziness, palpitation, spleen deficiency, poor appetite, loose stool, diarrhea, restlessness, palpitation, and insomnia. Modern pharmacological research considers that tuckahoe decoction, syrup and alcohol extract have the functions of diuresis, sedation, anti-tumor and increasing myocardial contraction respectively.

Radix Codonopsis is neutral in nature and sweet in taste, has effects of invigorating spleen and replenishing qi, invigorating spleen and benefiting lung, resisting cancer, lowering blood pressure, resisting anoxia, resisting aging, enhancing immunity, improving activity of superoxide dismutase, enhancing ability of eliminating free radicals, regulating gastrointestinal motility, resisting ulcer, inhibiting gastric acid secretion, and reducing pepsin activity. It is suitable for treating spleen and lung deficiency, short breath, palpitation, anorexia, loose stool, ulcer, anemia, asthma, cough, internal heat, and diabetes. The effective components of radix Codonopsis have exciting effect on nervous system, and can enhance organism resistance and increase erythrocyte and hemoglobin; the zinc contained in the product can promote growth and development and improve sexual function.

Prepared licorice root, radix Glycyrrhizae Praeparata has the effects of nourishing yin and blood, tonifying qi and activating yang, and recovering pulse and stopping palpitation. Mainly treats the syndrome of deficiency of both heart yin and yang, and later doctors expand the syndrome on the basis of the clinical application of Zhang Zhongjing to treat consumptive disease, consumptive lung disease, lung dryness and yin deficiency and other symptoms. Modern physicians are used for treating cardiovascular diseases and other systemic diseases, and are best in coordination with the properties of hundreds of drugs, so the term "old" is inherent.

Ginger, rhizoma Zingiberis recens, pungent in property and slightly warm in property, enters lung, spleen and stomach meridians. Has the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, relieving vomit, eliminating phlegm, relieving cough, and relieving fish and crab toxicity. It is commonly used for common cold due to wind-cold, spleen and stomach cold, stomach cold with vomiting, cold phlegm with cough. Modern pharmacological research believes that ginger can promote secretion of digestive juice and protect gastric mucosa, and has the effects of resisting ulcer, protecting liver, benefiting gallbladder, relieving fever, resisting bacteria, relieving pain and stopping vomiting. The alcohol extract can excite motor center, respiratory center and heart. Has different degrees of inhibiting and killing effects on various fungi.

The Chinese dates are sweet and warm in nature and enter spleen, stomach and heart meridians. Has the effects of invigorating spleen and replenishing qi, nourishing blood and tranquilizing mind. It is commonly indicated for poor appetite, asthenia, loose stool, irritability of women and insomnia. Modern pharmacological research shows that the date water decoction and the date polysaccharide can enhance muscle strength, increase weight, enhance endurance and resist fatigue; can promote bone marrow hematopoiesis, enhance immunity, improve energy metabolism of rats with qi and blood deficiency, promote calcium absorption, effectively reduce intestinal tract peristalsis time, and improve intestinal tract environment.

The radix Ophiopogonis is dry tuber of Ophiopogon japonicus of Liliaceae, is sweet and slightly bitter, and has effects of nourishing yin, moistening lung, benefiting stomach, promoting fluid production, clearing heart fire, and relieving restlessness. It is commonly indicated for dry cough due to lung dryness, cough due to yin deficiency, stomach yin deficiency, thirst due to body fluid consumption, constipation due to intestinal dryness, etc. Modern pharmacological studies show that radix ophiopogonis can enhance the phagocytic capacity of the reticuloendothelial system and increase peripheral white blood cells; the ophiopogonpolysaccharide can promote humoral immunity and cellular immunity, induce various cytokines, and play a role in resisting cancer by enhancing the immunity function.

Example one

The medicine for treating the liver cirrhosis is composed of the following medicines in parts by weight:

10g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9g of radix scutellariae, 9g of coptis chinensis, 12g of codonopsis pilosula, 12g of angelica sinensis, 12g of radix paeoniae alba, 12g of roasted turtle shell, 9g of mangnolia officinalis, 9g of fructus psoraleae, 10g of rhizoma atractylodis macrocephalae, 10g of poria cocos, 9g of honey-fried licorice root, 6g of ginger, 6g of Chinese date and 10g of radix ophiopogonis.

The same method as in the first embodiment

The medicines are prepared into formula granules, and the formula granules are taken with boiled water 2 boxes a day, 1 box is taken 1 hour after breakfast and supper every day, 30 days is one taking course, and 6 taking courses are taken.

50 patients with liver cirrhosis, manifested as hypochondriac pain, irritability, dry mouth, bitter taste, foreign body in pharynx, anorexia, abdominal distention, belch, breast pain or agglomeration, pale red tongue, thin and white tongue coating, and wiry pulse. The composition and the method are adopted, the clinical curative effect is evaluated in 3 months and 6 months after the medicine is taken according to the clinical symptom improvement rate of the patient and the imaging abdominal B-ultrasonic result, and the adverse reaction of the patient is observed. The results show that 50 patients with liver cirrhosis have no obvious curative effect in 7 patients, and the results of the abdominal B ultrasonography in the imaging department of the other patients after treatment have earlier reduced liver cirrhosis degree compared with the results of the abdominal B ultrasonography before treatment, the clinical effective rate is 86%, and the patients have obvious improvement in the aspects of pain, life quality and the like.

Example two

9g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9g of radix scutellariae, 9g of coptis chinensis, 12g of radix codonopsis, 10g of angelica sinensis, 10g of radix paeoniae alba, 12g of roasted turtle shell, 9g of mangnolia officinalis, 9g of fructus psoraleae, 12g of rhizoma atractylodis macrocephalae, 12g of poria cocos, 9g of honey-fried licorice root, 6g of ginger, 6g of Chinese date and 10g of radix ophiopogonis.

The same method as in the first embodiment

In 46 cases, the patients with liver cirrhosis had abdominal distension and fullness, or abdominal distension and fullness in the hypochondrium, abdominal distension and pain, abdominal distension and anorexia, nausea and vomiting, scanty urine, edema of lower limbs, loose and thin stools, white and greasy tongue coating, and thready and weak pulse. The composition and the method are adopted, the clinical curative effect is evaluated in 3 months and 6 months after the medicine is taken according to the clinical symptom improvement rate of the patient and the imaging abdominal B-ultrasonic result, and the adverse reaction of the patient is observed. The results show that 46 patients with liver cirrhosis have no obvious curative effect in 5 patients, and the results of the abdominal B ultrasonography in the imaging department of the other patients after treatment have earlier reduced liver cirrhosis degree compared with the results of the abdominal B ultrasonography before treatment, the clinical effective rate is 89.1%, and the life quality of the patients is obviously improved.

EXAMPLE III

9g of radix bupleuri, 9g of rhizoma pinelliae preparata, 12g of radix scutellariae, 12g of coptis chinensis, 12g of radix codonopsis, 12g of angelica sinensis, 12g of radix paeoniae alba, 12g of carapax trionycis preparata, 9g of mangnolia officinalis, 9g of fructus psoraleae, 10g of rhizoma atractylodis macrocephalae, 10g of poria cocos, 9g of radix glycyrrhizae preparata, 6g of ginger, 6g of Chinese date and 10g of radix ophiopogonis.

The same method as in the first embodiment

In 35 cases of patients with liver cirrhosis, yellow and stained eyes and skin, clear color, nausea or vomiting, dry mouth or halitosis, gastric cavity stuffiness, anorexia, abdominal distention, yellow and red urine, constipation, hypochondriac pain, yellow and greasy tongue coating, wiry and rapid pulse or slippery and rapid pulse. The prescription is taken according to the composition and the method, the clinical curative effect is evaluated in 3 months and 6 months after the patient takes the medicine according to the curative effect of the abdominal B-ultrasonic in the imaging and the clinical satisfaction degree, and the adverse reaction of the patient is observed. The results show that the curative effect is not obvious in 4 cases of 35 patients with the liver cirrhosis, the result of the abdominal B ultrasonography in the imaging department of other patients after treatment is earlier reduced than that of the abdominal B ultrasonography before treatment, and the clinical satisfaction rate is 88.6%.

Example four

9g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9g of radix scutellariae, 9g of coptis chinensis, 12g of codonopsis pilosula, 10g of angelica sinensis, 10g of radix paeoniae alba, 12g of roasted turtle shell, 9g of mangnolia officinalis, 10g of fructus psoraleae, 12g of rhizoma atractylodis macrocephalae, 12g of poria cocos, 9g of honey-fried licorice root, 6g of ginger, 6g of Chinese date and 8g of radix ophiopogonis.

The same method as in the first embodiment

In 48 cases of patients with liver cirrhosis, lumbago, soreness of the waist and knees, hypochondriac pain, fatigue, dry eyes, dysphoria with feverish sensation in chest, palms and soles or low fever, tinnitus, deafness, dizziness, blurred vision, constipation, scanty and brownish urine, red tongue with little coating, and thready or rapid pulse. The composition and the method are adopted, the clinical curative effect is evaluated in 3 months and 6 months after the patient takes the medicine according to the result of the abdominal B-ultrasonography, and the adverse reaction of the patient is observed. The results show that the results of the abdominal B ultrasonography in the imaging department of the other patients are reduced compared with the results of the abdominal B ultrasonography in the imaging department before the treatment except 6 patients with the type of cirrhosis patients with no obvious curative effect; the clinical effective rate is 84.2 percent, which shows that the curative effect of the recipe on treating the liver cirrhosis is obvious.

EXAMPLE five

9g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9g of radix scutellariae, 9g of coptis chinensis, 12g of radix codonopsis, 12g of angelica sinensis, 12g of radix paeoniae alba, 10g of roasted turtle shell, 9g of mangnolia officinalis, 10g of fructus psoraleae, 10g of rhizoma atractylodis macrocephalae, 10g of poria cocos, 9g of honey-fried licorice root, 6g of ginger, 6g of Chinese date and 10g of radix ophiopogonis.

The same method as in the first embodiment

36 patients with liver cirrhosis had abdominal distention, severe night-twitch, thin stool, sexual impotence, premature ejaculation, mental fatigue, cold, edema of lower limbs, clear and profuse urine, gastric distention, anorexia, sallow complexion, pale and swollen tongue with moist coating, deep, thready or slow pulse. The composition and the method of the medicine are adopted, the clinical curative effect is evaluated in 3 months and 6 months after the medicine is taken according to the curative effect of the abdominal B-ultrasonic in the imaging of the patient, and the adverse reaction of the patient is observed. The results show that 36 patients with liver cirrhosis have no obvious curative effect in 3 patients, and the results of the abdominal B ultrasonography in the imaging department of the other patients after treatment are all reduced in liver cirrhosis degree compared with the results of the abdominal B ultrasonography before treatment; the clinical effective rate is 91.7 percent, which shows that the curative effect of the recipe for treating the liver cirrhosis diseases is determined and the safety is high.

EXAMPLE six

9g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9g of radix scutellariae, 9g of coptis chinensis, 12g of codonopsis pilosula, 12g of angelica sinensis, 12g of radix paeoniae alba, 12g of roasted turtle shell, 6g of mangnolia officinalis, 10g of fructus psoraleae, 12g of rhizoma atractylodis macrocephalae, 12g of poria cocos, 9g of honey-fried licorice root, 6g of ginger, 6g of Chinese date and 8g of radix ophiopogonis.

The same method as in the first embodiment

42 patients with liver cirrhosis have hypochondriac pain such as stabbing, pain not moving, large, firm and full abdomen, no depression and hardness, exposed celiac tendon, mass under the hypochondrium, purple and dark lip color, red spots and red streaks on the abdominal wall, dark stool color, sublingual varicosity, purple and dark tongue, thready pulse or hollow pulse. The composition and the method are adopted, the clinical curative effect is evaluated in 3 months and 6 months after the patient takes the medicine according to the result of the abdominal B-ultrasonography, and the adverse reaction of the patient is observed. The results show that in 42 patients with liver cirrhosis, except 6 patients without obvious curative effect, the result of the abdominal B ultrasonography in the imaging department of the other patients after treatment is earlier reduced in the liver cirrhosis degree compared with the result of the abdominal B ultrasonography before treatment; the clinical effective rate is 85.7 percent, which shows that the curative effect of the recipe on the treatment of the liver cirrhosis is obvious.

The liver cirrhosis includes compensated liver cirrhosis and decompensated liver cirrhosis, the disease is named as 'accumulation' in the compensated liver cirrhosis, and the disease is named as 'tympanites' in the decompensated liver cirrhosis with ascites. Accumulation is caused by deficiency of healthy qi, dysfunction of the zang-fu organs, stagnation of qi, blood stasis, and phlegm accumulation in the abdomen, manifested as agglomeration, pain or distension in the hypochondrium. The swelling is caused by accumulation, which may cause further aggravation of the disease, swelling like bulging of the abdomen, moving and turbid sound, accompanied by abdominal mass, gingival and epistaxis, or red nevus and blood streak on the neck, chest and upper limbs, or lassitude, weakness, poor appetite, loose stool, or symptoms such as high fever, dysphoria, coma, delirium, and skin ecchymosis. In the formula, radix bupleuri soothes liver and benefits gallbladder, radix scutellariae and rhizoma coptidis clear away heat and toxic materials and dry dampness, angelica sinensis enriches blood and activates blood, radix paeoniae alba softens liver and relieves pain, poria cocos and rhizoma atractylodis macrocephalae invigorate spleen and eliminate dampness, codonopsis pilosula invigorates qi, benefits blood and promotes production of body fluid, fructus psoraleae invigorates spleen and kidney, radix ophiopogonis invigorates qi, nourishes yin, carapax amydae softens hardness and dissipates stagnation, immature bitter orange and mangnolia officinalis break qi and dissipate stagnation, honey-.

The above-mentioned embodiment is only one of the preferred embodiments of the present invention, and should not be used to limit the scope of the present invention, but all the insubstantial modifications or changes made within the spirit and scope of the main design of the present invention, which still solve the technical problems consistent with the present invention, should be included in the scope of the present invention.

Claims

1. A pharmaceutical formulation for treating liver cirrhosis is characterized in that: according to the weight ratio, the traditional Chinese medicine composition comprises 9-10g of radix bupleuri, 9g of rhizoma pinelliae preparata, 9-12g of radix scutellariae, 9-12g of coptis chinensis, 12g of codonopsis pilosula, 10-12g of angelica sinensis, 10-12g of radix paeoniae alba, 10-12g of roasted turtle shell, 6-9g of mangnolia officinalis, 8-10g of fructus psoraleae, 10-12g of rhizoma atractylodis macrocephalae, 10-12g of poria cocos, 9g of roasted liquorice, 6g of ginger, 6g of Chinese date and 8-10g of radix ophiopogon.