CN111000773A - Preparation method of pholiota nameko mucilage and skin care product and beauty food prepared from pholiota nameko mucilage - Google Patents

Preparation method of pholiota nameko mucilage and skin care product and beauty food prepared from pholiota nameko mucilage Download PDF

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CN111000773A
CN111000773A CN201911419464.5A CN201911419464A CN111000773A CN 111000773 A CN111000773 A CN 111000773A CN 201911419464 A CN201911419464 A CN 201911419464A CN 111000773 A CN111000773 A CN 111000773A
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parts
extract
mucilage
pholiota nameko
skin care
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周伦辉
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
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    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61Q19/08Anti-ageing preparations
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
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    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92Oral administration

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Abstract

The invention discloses a preparation method of pholiota nameko mucilage, and a skin care product and a beauty food prepared from the pholiota nameko mucilage, and the preparation method of the pholiota nameko mucilage comprises the steps of cleaning raw pholiota nameko, processing at the temperature of 105-121 ℃ for 25-40 minutes under the pressure of 0.15-0.35MPa, and filtering to obtain the pholiota nameko mucilage; a skin care product prepared by using nameko mushroom mucilage specifically comprises the application of preparing essence, a facial mask, toner, cream, eye cream and the like; a skin caring food prepared from Pholiota nameko mucilage specifically comprises application in preparing oral liquid. The pholiota nameko mucilage prepared by the method can be directly added into cosmetics and food, and preservatives can also be added to be used as raw materials for storage and standby application, so that the safety and the reliability are realized, and the raw materials of the pholiota nameko are fully utilized.

Description

Preparation method of pholiota nameko mucilage and skin care product and beauty food prepared from pholiota nameko mucilage
Technical Field
The invention relates to the field of medicine preparation and application, in particular to a preparation method of pholiota nameko mucilage and a skin care product and a beauty food prepared from the pholiota nameko mucilage.
Background
Pholiota nameko (Pholiota nameko) also known as pearl mushroom, Pholiota nameko and Pholiota nameko is named because of the abundant mucus on the surface. The pholiota nameko mucilage contains nucleic acid, protein, 17 amino acids, pholiota nameko polysaccharide and other components, and the pholiota nameko polysaccharide and the nucleic acid are main active ingredients of the pholiota nameko mucilage. Wherein the polysaccharide has biological activities of resisting oxidation, clearing free radicals and the like, and the pholiota nameko polysaccharide has the capacity of eliminating DPPH free radicals which is close to Vc and reaches 41.28 percent at high-quality concentration (800 mu g/mL); pholiota nameko polysaccharide pair Fe2+The induced lipid peroxidation has a certain inhibition effect, and the inhibition effect is gradually enhanced along with the increase of the concentration. The natural nucleic acid has certain stimulation effect on frontal keratinized cells of human body, can regenerate and renew cells, absorb ultraviolet rays, prevent long spots, has the characteristics of ultraviolet resistance, aging resistance, moisture retention and the like, and has better sticky feeling and lubricating feeling.
The pholiota nameko raw material adopted in the current market is dehydrated dry pholiota nameko, and the pholiota nameko raw material is prepared by extraction and processing, so that a large amount of nutrient components are lost, the application effect is limited, and pholiota nameko mucilage is directly discarded, so that the resource waste is caused.
With the continuous development of daily chemical technology, natural cosmetics are favored due to the characteristics of high efficiency, safety, no stimulation and the like, and the market demand is increasing day by day. The natural nucleic acid contained in the pholiota nameko mucilage has the characteristics of ultraviolet resistance, aging resistance, moisture retention and the like, has better sticky feeling and lubricating feeling, and can reduce or replace a thickening agent, a lubricating agent and a moisturizing agent when being added into cosmetics. Cosmetic thickeners on the market such as xanthan gum, carbomer, silicified polymer, high molecular hyaluronic acid, acrylic acid (ester) and the like, cosmetic lubricants such as silicone oil, glycerin, silicide polymer and the like, cosmetic moisturizing agents such as alcohols, low molecular hyaluronic acid, silanes and the like, and the raw materials often have allergic reaction after being used by people; the pholiota nameko mucilage is natural in components, chemical treatment is not needed in the preparation process, so that the pholiota nameko mucilage is higher in safety, and the pholiota nameko mucilage is more remarkable in beautifying effect after being compounded with other biological raw materials.
The pholiota nameko oral liquid produced by utilizing pholiota nameko mucilage is not available in the market, food-grade thickening agents are added into most of other existing beautifying oral liquids, and the pholiota nameko mucilage has viscosity, so that the thickening agents do not need to be additionally added. In addition, aiming at people who are easy to get inflamed and allergic, the invention avoids using collagen, thickening agent, spice, sugar, thermal Chinese herbal medicine and plant components which are easy to get inflamed, and all adopts natural raw materials which are not easy to get inflamed and are not allergic.
Therefore, the need exists for a safe and efficient pholiota nameko mucilage, and further development of application of the pholiota nameko mucilage is needed. In order to solve the problems, the functional components of the pholiota nameko mucilage need to be further defined, the safety and the effectiveness of the pholiota nameko mucilage are verified, and the application field of the pholiota nameko mucilage is widened.
Disclosure of Invention
Aiming at the problems, the invention researches and designs a preparation method of pholiota nameko mucilage and a skin care product and a beauty food prepared from the pholiota nameko mucilage so as to solve the problems of resource waste caused by large loss of nutrient components and insufficient application of the pholiota nameko mucilage in the traditional pholiota nameko raw material extraction process. The technical means adopted by the invention are as follows:
a preparation method of pholiota nameko mucilage comprises the following steps: cleaning raw pholiota nameko, treating at the temperature of 105-.
Preferably, the treatment temperature is 121 ℃, the treatment time is 30 minutes, and the treatment pressure is 0.35 MPa.
A skin care product prepared from the pholiota nameko mucilage comprises the following components in parts by weight: 50-100 parts of distilled water, 3-10 parts of pholiota nameko mucilage, 0.25-0.5 part of soybean oligopeptide, 2-6 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.5 part of polyhydric alcohol, 0.5-2 parts of tree peony bark extract, 3-10 parts of tremella polysaccharide extract, 1-3 parts of cherry extract, 2-3 parts of centella extract, 1-2 parts of plant compound anti-allergic factor, 0.15-0.8 part of sclerotium rolfsii gum, 2-10 parts of hydrogenated starch hydrolysate and 0.5-1 part of PE 9010.
Preferably, the skin care product is essence and comprises the following components in parts by weight: 60-70 parts of distilled water, 3-8 parts of nameko mushroom mucus, 0.25-0.35 part of soybean oligopeptide, 3-5 parts of polypeptide compound source liquid, 3-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 5-8 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella asiatica extract, 5-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.5-0.7 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylate/C10-30 alkanol acrylate cross-linked polymer, 5-8 parts of yeast lysate 908 parts, 2-5 parts of hydrogenated starch hydrolysate, 2-3 parts of pomegranate extract, 0.02-0.04 part of 4-hydroxyethyl piperazine ethanesulfonic acid and 0.5-0.8 part of PE 10.
Preferably, the skin care product is a mask which comprises the following components in parts by weight: 70-80 parts of distilled water, 3-8 parts of nameko mushroom mucus, 0.25-0.35 part of soybean oligopeptide, 2-3 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 5-8 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella asiatica extract, 10-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.3-0.5 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylate/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of yeast lysate 909010 parts, 2-4 parts of hydrogenated starch hydrolysate, 1-2 parts of pomegranate extract, 0.01-0.02 part of 4-hydroxyethyl piperazine ethanesulfonic acid and 0.5-0.8 part of PE 10.
Preferably, the skin care product is toner which comprises the following components in parts by weight: 80-90 parts of distilled water, 3-5 parts of pholiota nameko mucilage, 0.3-0.5 part of soybean oligopeptide, 2-3 parts of polypeptide compound source liquid, 2-3 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella extract, 10-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.15-0.25 part of sclerotium rolfsii gum, 2-3 parts of hydrogenated starch hydrolysate and 0.5-0.8 part of PE 9010.
Preferably, the skin care product is a face cream which comprises the following components in parts by weight: 60-70 parts of distilled water, 3-5 parts of nameko mushroom mucus, 0.25-0.3 part of soybean oligopeptide, 3-4 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella extract, 1-2 parts of plant compound anti-allergic factor, 0.6-0.7 part of sclerotium rolfsii gum, 0.05-0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of hydrogenated starch hydrolysate, 1-3 parts of pomegranate extract, 0.05-0.1 part of pearl powder, 3-5 parts of emulsifier, 10-15 parts of vegetable oil, 2-5 parts of organosilicon 9010 and 0.5-0.8 part of PE 9010.
Preferably, the skin care product is eye cream which comprises the following components in parts by weight: 50-60 parts of distilled water, 3-5 parts of nameko mushroom mucus, 0.25-0.3 part of soybean oligopeptide, 3-4 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of tree peony bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of asiatic centella extract, 1-2 parts of plant composite anti-allergic factor, 0.6-0.7 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of hydrogenated starch hydrolysate, 1-2 parts of pomegranate extract, 3-5 parts of emulsifier, 5-10 parts of vegetable oil, 990510-15 parts of organic silicon, 1-3 parts of safflower extract and 2-5 parts of millet extract, 2-4 parts of elderberry extract and 0.5-0.8 part of PE 9010.
A beauty food prepared by applying the pholiota nameko mucilage comprises the following components in parts by weight: 50-70 parts of purified water, 5-10 parts of pholiota nameko mucilage, 5-10 parts of soybean oligopeptide, 5-10 parts of sea buckthorn stock solution, 5-10 parts of honey and 5-10 parts of blueberry concentrated solution.
Preferably, the beauty food is oral liquid which comprises the following components in parts by weight: 50-70 parts of purified water, 5-10 parts of pholiota nameko mucilage, 5-10 parts of soybean oligopeptide, 5-10 parts of sea buckthorn stock solution, 5-10 parts of honey and 5-10 parts of blueberry concentrated solution.
Compared with the prior art, the preparation method of the pholiota nameko mucilage and the skin care product and the beauty food prepared from the pholiota nameko mucilage have the following beneficial effects:
1. the pholiota nameko mucilage prepared by the method can be directly added into cosmetics and food, and preservatives can also be added to be used as raw materials for storage and standby application, so that the safety and the reliability are realized, and the raw materials of the pholiota nameko are fully utilized.
2. The pholiota nameko mucilage prepared by the method is used as an ideal thickening agent, lubricant or humectant, so that the viscosity and the softness of the product can be effectively improved; it has no toxicity to melanocyte, epidermal cell and dermal cell; non-sensitizing, carcinogenic, teratogenic; the stability is good.
3. The pholiota nameko mucilage is applied to beauty care products, such as essence, emulsion, toner, mask, cream and the like, and can resist oxidation, whiten skin, remove color spots, remove wrinkles, repair, preserve moisture, enhance skin smoothness and improve skin sensitivity; compared with the existing beauty products, the pholiota nameko mucilage disclosed by the invention has a better effect and higher safety.
4. The pholiota nameko mucilage is prepared into beauty and health care food in the forms of oral liquid, beverage and the like, and can improve the immunity and the oxidation resistance of a human body, promote metabolism, clear free radicals in the body and prevent diseases.
Detailed Description
Example 1:
a preparation method of pholiota nameko mucilage comprises the following steps: cleaning fresh pholiota nameko cultured in a dust-free room, removing attachments on the surface layer, putting into a sealed tank made of a high-temperature resistant material, sealing, sending into an autoclave, setting the pressure to be 0.35MPa, the temperature to be 121 ℃, sterilizing for 30 minutes, fusing the water in the pholiota nameko subjected to high-pressure high-temperature sterilization with surface-layer nucleic acid polysaccharide amino acid to generate mucus, and filtering the obtained pholiota nameko raw material to obtain the pholiota nameko mucus. The pholiota nameko mucilage subjected to high-temperature and high-pressure treatment can be filtered to obtain 450ml per 1kg on average.
Example 2:
when the pholiota nameko mucilage is used as a softening agent, a moisturizing agent or a thickening agent to prepare a skin care product, the effects of inhibiting the generation of melanin, removing skin pigment deposition and pigmented spots, repairing acne, promoting the renewal of aged skin, enhancing the smoothness of the skin, improving the skin sensitivity, increasing the moisture content of the skin, enhancing the skin elasticity, resisting wrinkles and resisting aging are achieved.
Comparative example 1:
the effect of the pholiota nameko mucilage and a common thickener are evaluated and compared.
When the pholiota nameko mucilage is used as a skin care product thickener in an amount of 10-30%, no anaphylactic reaction occurs in 30 sensitive people; conventional thickeners such as sodium hyaluronate, sodium alginate, hydroxycellulose, xanthan gum, locust bean gum, and carbomer are added according to the minimum recommended addition level, and all people have allergy.
Therefore, the pholiota nameko mucilage is superior to other thickening agents in the aspect of safety as a skin care product thickening lubricant.
Comparative example 2:
and evaluating and comparing the action effects of the pholiota nameko mucilage and the common emollient.
The sclerotium rolfsii and the pholiota nameko mucilage are safe plant-derived emollients, humectants and thickeners, and cannot cause allergy even if the addition amount is large. When the essence and the facial mask are prepared, the skin feel is sticky when the addition amount of the sclerotium rolfsii powder reaches more than 0.7 percent; if the addition amount is less than 0.5%, the liquid fluidity is too large, and the lubrication degree is not enough; after 5% -15% of pholiota nameko mucilage is added, the skin feel of the product is the same as that of the product added with 1% -2% of silicone oil, but the silicone oil belongs to chemicals, is not easy to absorb and is easy to cause acne.
Comparative example 3:
and evaluating and comparing the action effect of the pholiota nameko mucilage and a common humectant.
The comparison of pholiota nameko mucilage and humectants such as butanediol, sodium hyaluronate, etc. was evaluated.
5-15% of pholiota nameko mucilage is added to prepare a mask, after the mask is applied to the face for 20 minutes, no anaphylactic reaction occurs in the test of 10 sensitive people, and the dry skin is obviously improved; after other moisturizers such as butanediol or sodium hyaluronate are added into the facial mask according to the minimum standard of the recommended addition amount, people have different degrees of allergy within 10 minutes to 24 hours.
Therefore, the pholiota nameko mucilage is superior to other moisturizing agents in the aspect of safety as a skin care product moisturizing agent.
According to comparative examples 2 and 3, the pholiota nameko mucilage can increase the lubrication degree, is safer than silicone oil, can reduce the addition amount of sclerotium rolfsii gum, and is a very safe plant-derived emollient, humectant or thickener as the sclerotium rolfsii gum. Therefore, a part of the pholiota nameko mucilage and the sclerotium rolfsii gum can be selected to be compounded into an emollient, a humectant or a thickening agent to be added into the skin care product for use.
Example 3:
a skin care product prepared by using pholiota nameko mucilage comprises the following components in parts by weight: 50-100 parts of distilled water, 3-10 parts of nameko mushroom mucus, 0.25-0.5 part of soybean oligopeptide, 2-6 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.5 part of polyhydric alcohol, 0.5-2 parts of tree peony bark extract, 3-10 parts of tremella polysaccharide extract, 1-3 parts of cherry extract, 2-3 parts of asiatic centella extract, 5-15 parts of rose extract, 1-3 parts of safflower extract, 2-5 parts of common euphorbia herb extract, 2-4 parts of elderberry extract, 1-2 parts of plant compound anti-allergic factor, 0.15-0.8 part of sclerotium rolfsii gum, 0.05-0.3 part of acrylic acid (ester)/C10-30 acrylate alkanol cross-linked polymer, 2-8 parts of schizosaccharomyces cerevisiae lysate fermentation product, 2-10 parts of hydrogenated starch hydrolysate, 1-5 parts of pomegranate extract, 0.5-5 parts of emulsifier, 0.01-0.04 part of 4-hydroxyethyl piperazine ethanesulfonic acid, 5-15 parts of vegetable oil, 0.05-0.1 part of pearl powder, 2-15 parts of organic silicon 9905 and 0.5-1 part of PE 9010.
The amount of the above components can be selected by those skilled in the art according to the needs, so as to prepare different specific application forms of toner, essence, emulsion, facial mask, cream, shampoo, hair conditioner and the like. It will be appreciated that, in addition to the ingredients particularly mentioned above, the formulations of the invention may include excipients or carriers conventional in the art having regard to the type of formulation in question. In addition to the preservatives described above, other preservatives or non-preservative substitutes may also be used.
Among the raw materials, the soybean oligopeptide is a non-transgenic soybean zymolyte with the average molecular weight of 500-1500, has small molecular weight, is easy to be absorbed by skin, and has the functions of replenishing water, resisting oxidation and enhancing skin immunity.
The polypeptide compound source liquid is water solution prepared from seven amino acids with different sequences, specifically 0.001% nonapeptide-1, 0.001% tripeptide-1 (GHK), 0.001% palmitoyl tripeptide-5, 0.0002% oligopeptide, 0.0002% snake venom peptide, 2% blue copper peptide and 0.002% hexapeptide, and the seven amino acids respectively have the effects of resisting wrinkles, whitening skin, promoting the growth of subcutaneous collagen and repairing skin injury.
The natural amino acid humectant is proline, and is effective component extracted from fructus Lycii and herba Zosterae Marinae.
The polyalcohol is a compound of caprylyl hydroximic acid, butanediol and 1, 2 hexanediol, and has antibacterial and antiseptic effects.
The moutan bark extract, the tremella polysaccharide extract, the cherry extract, the centella asiatica extract, the rose extract, the safflower extract, the eyebright extract and the elderberry extract are all effective substances obtained by water extraction. Wherein, the moutan bark extract has the functions of antibiosis and antisepsis; the tremella polysaccharide is rich in natural plant colloid, can moisten skin in cosmetic application, and has the effects of removing chloasma and freckle on the face; the vitamin C in the cherry extract can promote skin collagen proliferation, the skin can keep moisture and elasticity by being supplemented with moisturizing ingredients such as amino acid proline, sclerotium rolfsii gum and the like, and the cherry contains a tartaric acid ingredient, so that dead skin can be removed, pores can be effectively compacted, the surface of the skin is smooth, and the texture of the skin is more delicate; the herba Centellae extractive solution has effects of diminishing inflammation and calming, stimulating deep skin cell replacement, tightening the connection part of epidermis and dermis, promoting collagen formation in dermis, regenerating fibrin, and promoting the healing of damaged tissue; the rose extract has the functions of supplementing water, moisturizing and promoting capillary vasoconstriction; the safflower extract, the eyebright extract and the elderberry extract can improve eye blood circulation and relieve dark circles.
The plant composite anti-allergic factor is a 30% aqueous solution obtained by extracting centella asiatica, giant knotweed rhizome, baical skullcap root, tea extract, glabrous licorice root, chamomile and rosemary with water, and has the effects of relieving allergy, diminishing inflammation, resisting oxidation, resisting aging, preserving moisture and whitening as a multi-herb anti-allergic agent.
Sclerotium rolfsii gum is a water-soluble biopolymer produced by fermentation using mushroom as a substrate. The sclerotium rolfsii gum is a low-risk component which is considered to be safe by a cosmetic database at 99%, has good applicability in a wide pH value range, has great tolerance to various electrolytes in a solution, has high pseudoplasticity, and has little change of the viscosity of the solution along with the rise and fall of the temperature. Meanwhile, the skin care product has the effects of diminishing inflammation, preserving moisture, repairing and removing free radicals and has the natural effect of relieving the skin. Sclerotinia sclerotiorum gum can help to stabilize the emulsion and control viscosity according to the cosmetic database [2 ]. It can be used in cosmetics for preventing pigment separation, and has effects of softening, moistening, thickening, and scavenging free radicals by compounding with mucor of nameko with biological activities of resisting oxidation, resisting tumor, resisting aging, and enhancing immunity.
The lysate of the yeast fermentation product of the bifidus is a complex of metabolite, cytoplasmic fragments, cell wall components and polysaccharide obtained after the culture, inactivation and decomposition of bifidobacterium. The lysate of the yeast fermentation product of the bifidus can help epidermal cells and dermal cells to resist the harmful effect of UVB rays, promote DNA repair, generate small molecules such as vitamin B groups, minerals and amino acids which are beneficial to skin care, strengthen the metabolism of cuticle, capture free radicals, inhibit the peroxidation of lipid and have the functions of whitening and resisting aging.
The hydrogenated starch hydrolysate is formed by fermenting plants, is a mixture with viscous, colorless and cool feeling, mainly contains maltooligosaccharide glucoside/hydrogenated starch hydrolysate, has no stimulation to skin, protects the skin from external damage, has long moisturizing time, promotes cell growth, prevents cell drying, protects cells, avoids ultraviolet ray from damaging the cells, has an anti-inflammatory effect, improves the rough skin effect, inhibits the generation of anaerobic bacteria (acne bacteria), and can improve the fineness of foam of the product in a washing product to ensure that the foam lasts longer. And can improve hair dryness and wet combing property, repair damaged hair, and protect hair.
The pomegranate extract is a newly discovered skin-beautifying sanctus, contains anthocyanin and polyphenol, has quite excellent antioxidant effect, wherein anthocyanidin (ellagic acid) has the effect of resisting inflammation, and is a whitening component published by health agencies, so that the pomegranate extract stock solution can be used for skin care, can strengthen skin cells to resist free radicals, and can be used for caring skin even for allergic skin.
4-hydroxyethyl piperazine ethanesulfonic acid can very mildly promote the old keratinocyte peeling of the skin epidermal layer. Can smooth and soften skin, brighten skin color and achieve the effect of whitening.
The vegetable oil is refined pure Shea butter from Africa, and has effects of no allergy, moistening and keeping moisture.
According to different types of skin care products prepared from the raw materials, 20 volunteers aged 30-45 years are tested, and no anaphylactic reaction occurs after feedback. After 2 months of use, the canthus wrinkles are obviously improved by the feedback of a 32-year-old user. Through feedback of a 37-year-old acne patient, the inflammation is improved by 30% after 1 day of use, the acne starts to scab and fall off after 2-3 days of use, and the acne mark disappears by 40% after 1 week of use. After one allergy patient tests feedback, after the skin care product is used for 2 days, the allergy symptoms are obviously improved, new skin grows out, and the damaged skin gradually falls off.
Example 4:
the skin care product prepared by using the pholiota nameko mucilage as an active ingredient of the present invention may further contain adjuvants commonly used in beauty care and skin care, such as hydrophilic or lipophilic gelling agents, hydrophilic or lipophilic active agents, preservatives, antioxidants, solvents, perfumes, sunscreens, pigments, fragrance absorbents and colorants. The amount of each adjuvant can be selected by one skilled in the art as desired.
Active agents that may be used in conjunction with the pholiota nameko mucilage of the present invention include, but are not limited to, ellagic acid and derivatives thereof, hydroquinone, arbutin, resorcinol and derivatives thereof, vitamin C and derivatives thereof, pantothenic acid sulfonate and derivatives thereof, kojic acid, placental extract, molecules that directly or indirectly interfere with α -melanotropin (α -MSH) or its receptors or adrenocorticotropic hormone (ACTH), polyols such as glycerol, ethylene glycol or propylene glycol, vitamins, keratolytic or desquamating agents such as salicylic acid and derivatives thereof, α -hydroxyacids such as lactic acid or malic acid, ascorbic acid and derivatives thereof, retinoic acid, retinal, retinol and derivatives thereof, anti-inflammatory agents, emollients and mixtures thereof, chemical or physical sun screening agents such as zinc oxide micronized, titanium oxide, butyl methoxydibenzoylmethane and methoxyoctyl cinnamate, and deoxyribonucleic acid and nucleic acids.
An emulsion prepared by using the pholiota nameko mucilage comprises common raw material substances in the field, such as pholiota nameko mucilage, oil, an emulsifier, a co-emulsifier and the like, wherein the weight percentage of a lipid phase can be 5-80%, and is preferably 5-50%; the proportion by weight of emulsifier and co-emulsifier may be from 0.3 to 30%, preferably from 0.5 to 10%.
Of the above materials, oils include mineral oils, oils of vegetable origin (such as jojoba oil, shea butter), oils of animal origin (such as lanolin) or synthetic oils (such as perhydrosqualene), and in addition, fatty alcohols, fatty acids and waxes can be used as the fatty substance.
Emulsifiers and co-emulsifiers include glycoside emulsifiers of vegetable origin (e.g., stearyl alcohol and coco glucoside), fatty alcohol polyethers (e.g., laureth-7), sodium polyacrylates (e.g., sodium polyacrylate c 18-21-alkyltrideceth-6), and fatty acid esters of glycerol (e.g., glyceryl stearate).
Example 5:
a beauty food prepared by using pholiota nameko mucilage comprises but is not limited to oral liquid, syrup, dairy products and beverage forms, and the beauty food comprises the following components in parts by weight: 50-70 parts of purified water, 5-10 parts of nameko mushroom mucus, 5-10 parts of soybean oligopeptide, 5-10 parts of sea-buckthorn stock solution, 5-10 parts of honey, 5-10 parts of blueberry concentrated solution and potassium sorbate (according to the national standard).
Furthermore, as the pholiota nameko mucilage is prepared by specially selecting the pholiota nameko fresh mushrooms as the raw material, the obtained mucilage can be directly taken, the dose is 30ML-60ML per day, and the bioavailability of the extract can be improved.
Further, the soybean oligopeptide is a non-transgenic soybean zymolyte with the average molecular weight of 500-1500; the sea-buckthorn stock solution is pure sea-buckthorn juice without additives; the blueberry concentrated solution is organic wild blueberry without additives, and is prepared by 5-8 times of concentration and fermentation.
The preparation method of the oral liquid can select conventional antiseptic in the field, and can also use high temperature and high pressure sealed package without antiseptic.
In the raw materials, the pholiota nameko mucilage has the effects of promoting immunity, resisting aging and the like, and the pholiota nameko polysaccharide has biological activities of resisting oxidation, resisting tumors, resisting aging, enhancing immunity and the like.
The soybean oligopeptide has certain antioxidant capacity and can help human body resist free radicals, because histidine and tyrosine in the residue can eliminate the free radicals or chelate metal ions. Can inhibit the activity of angiotensin converting enzyme, thereby preventing peripheral vasoconstriction, and lowering blood pressure, without lowering blood pressure for normal blood pressure. The soybean oligopeptide can prolong exercise time, increase the content of muscle glycogen and liver glycogen, and reduce the content of lactic acid in blood, thereby relieving fatigue. The soybean oligopeptide can promote bile acidification, effectively discharge cholesterol, and prevent excessive absorption of cholesterol, thereby reducing blood lipid and blood cholesterol concentration. The soybean oligopeptide can reduce the content of cholesterol and triglyceride in vivo, stimulate the secretion of CCK (cholecystokinin), regulate the food intake of organism, and increase satiety. In addition, the soybean peptide also has the effects of regulating immunity, reducing blood sugar and the like. The molecular weight of soybean polypeptide is below 1000 on average, and the oligomerization reaches the level of being directly absorbed by human intestinal tract.
The fructus Hippophae stock solution has effects of promoting blood circulation and removing blood stasis. The total flavone contained in fructus Hippophae has effects of improving myocardial microcirculation, reducing oxygen consumption of myocardium, and can be used for treating angina pectoris, improving myocardial blood supply state, and enhancing heart function. The sea-buckthorn has the effects of promoting digestion, resolving stagnation, strengthening spleen and nourishing stomach, and the nutritional elements contained in the sea-buckthorn can effectively protect gastric mucosa and inhibit the secretion of gastric acid, so that the damage degree of the gastric mucosa is reduced, and the sea-buckthorn has good effects on dyspepsia, gastritis, chronic constipation and the like. The sea buckthorn contains abundant vitamins, wherein vitamin C, vitamin A, vitamin E and carotenoid are main skin care components, and VC has the effects of oxidation resistance, whitening and spot fading. The superoxide dismutase contained in fructus Hippophae has the functions of regulating immune system, regulating immune cells, improving disease resistance, and delaying aging. The sea-buckthorn is called the king of vitamin C, and a large amount of vitamin C can improve the oxygen content of brain cells of people and is beneficial to relieving fatigue. The sea-buckthorn contains rich amino acids, so that the sleep of people can be effectively improved, the memory can be improved, and the normal activity of the nervous system can be maintained. Sea buckthorn has the function of blocking and preventing the horrible carcinogen N-dimethyl nitrosamine. The flavone component contained in fructus Hippophae has anticancer effect.
The blueberry concentrated solution can enhance the resistance of human bodies to infectious diseases. Blueberry berries contain abundant high fiber and can be used as a good source of fiber in daily diet. Blueberry also contains abundant potassium, and can help to maintain the balance of body fluid, normal blood pressure and heart function. Anthocyanidin in blueberry fruit is a very strong antioxidant, and can help prevent the formation of intra-arterial plaque and various cancers and reduce the possibility of cancer. Research of USDA shows that the blueberry has the strongest antioxidant capacity in more than 40 fruits and vegetables which are frequently eaten by people, which means that more antioxidants capacity against aging, cancer and heart diseases can be realized by eating the blueberry. The blueberry is rich in vitamin C, has the effects of enhancing cardiac function, preventing cancer and heart disease, preventing cranial nerve aging and improving mental power, and also has certain improvement effect on common cold, throat pain and diarrhea. Researches show that the anthocyanin pigment has good health-care effect on eyes, can relieve eye fatigue and improve night vision, and the anthocyanin pigment rich in the blueberry fruit is particularly suitable for people with long-term work of eyes.
The skin caring health food prepared from the above materials has natural fruit taste, and does not need essence and sweetener harmful to human body. According to the condition that physiological functions of a human body after the age of 30 years are gradually declined, the immunity and the oxidation resistance of the human body are improved, metabolism is promoted, free radicals in the human body are cleared, and diseases are prevented, the raw materials are prepared into a beauty and health food containing pholiota nameko mucus, and 10 volunteers between the age of 30 and the age of 65 are tested.
The test result is fed back by 1 user of 37 years old, and the gastric acid regurgitation condition is improved after 1 month of use; after the feedback of a 60-year-old user, the sleep quality is improved after the use for 1 month; after the feedback of a 37-year-old user, the mental condition is improved after the use for 2 months; the feedback of 7 testers shows that the body resistance is improved after 1 month of use; there were 6 subjects who had feedback and improved the rough skin pigmentation after 2 months of use; none of the above subjects had symptoms of allergy and excessive internal heat.
The above-mentioned embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements of the technical solution of the present invention by those skilled in the art should fall within the protection scope defined by the claims of the present invention without departing from the spirit of the present invention.

Claims (10)

1. A preparation method of pholiota nameko mucilage is characterized by comprising the following steps: the method comprises the following steps: cleaning raw pholiota nameko, treating at the temperature of 105-.
2. The preparation method of pholiota nameko mucilage according to claim 1, wherein the preparation method comprises the following steps: the treatment temperature was 121 ℃, the treatment time was 30 minutes, and the treatment pressure was 0.35 MPa.
3. A skin care product prepared by applying the pholiota nameko mucilage of claim 1, wherein the skin care product comprises the following components in parts by weight: the paint comprises the following components in parts by weight: 50-100 parts of distilled water, 3-10 parts of pholiota nameko mucilage, 0.25-0.5 part of soybean oligopeptide, 2-6 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.5 part of polyhydric alcohol, 0.5-2 parts of tree peony bark extract, 3-10 parts of tremella polysaccharide extract, 1-3 parts of cherry extract, 2-3 parts of centella extract, 1-2 parts of plant compound anti-allergic factor, 0.15-0.8 part of sclerotium rolfsii gum, 2-10 parts of hydrogenated starch hydrolysate and 0.5-1 part of PE 9010.
4. The skin care product prepared by using the pholiota nameko mucilage of claim 1 according to claim 3, wherein the skin care product comprises: the skin care product is essence and comprises the following components in parts by weight: 60-70 parts of distilled water, 3-8 parts of nameko mushroom mucus, 0.25-0.35 part of soybean oligopeptide, 3-5 parts of polypeptide compound source liquid, 3-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 5-8 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella asiatica extract, 5-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.5-0.7 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylate/C10-30 alkanol acrylate cross-linked polymer, 5-8 parts of yeast lysate 908 parts, 2-5 parts of hydrogenated starch hydrolysate, 2-3 parts of pomegranate extract, 0.02-0.04 part of 4-hydroxyethyl piperazine ethanesulfonic acid and 0.5-0.8 part of PE 10.
5. The skin care product prepared by using the pholiota nameko mucilage of claim 1 according to claim 3, wherein the skin care product comprises: the skin care product is a facial mask which comprises the following components in parts by weight: 70-80 parts of distilled water, 3-8 parts of nameko mushroom mucus, 0.25-0.35 part of soybean oligopeptide, 2-3 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 5-8 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella asiatica extract, 10-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.3-0.5 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylate/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of yeast lysate 909010 parts, 2-4 parts of hydrogenated starch hydrolysate, 1-2 parts of pomegranate extract, 0.01-0.02 part of 4-hydroxyethyl piperazine ethanesulfonic acid and 0.5-0.8 part of PE 10.
6. The skin care product prepared by using the pholiota nameko mucilage of claim 1 according to claim 3, wherein the skin care product comprises: the skin care product is toner which comprises the following components in parts by weight: 80-90 parts of distilled water, 3-5 parts of pholiota nameko mucilage, 0.3-0.5 part of soybean oligopeptide, 2-3 parts of polypeptide compound source liquid, 2-3 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella extract, 10-15 parts of rose extract, 1-2 parts of plant compound anti-allergic factor, 0.15-0.25 part of sclerotium rolfsii gum, 2-3 parts of hydrogenated starch hydrolysate and 0.5-0.8 part of PE 9010.
7. The skin care product prepared by using the pholiota nameko mucilage of claim 1 according to claim 3, wherein the skin care product comprises: the skin care product is a face cream which comprises the following components in parts by weight: 60-70 parts of distilled water, 3-5 parts of nameko mushroom mucus, 0.25-0.3 part of soybean oligopeptide, 3-4 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of moutan bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of centella extract, 1-2 parts of plant compound anti-allergic factor, 0.6-0.7 part of sclerotium rolfsii gum, 0.05-0.15 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of hydrogenated starch hydrolysate, 1-3 parts of pomegranate extract, 0.05-0.1 part of pearl powder, 3-5 parts of emulsifier, 10-15 parts of vegetable oil, 2-5 parts of organosilicon 9010 and 0.5-0.8 part of PE 9010.
8. The skin care product prepared by using the pholiota nameko mucilage of claim 1 according to claim 3, wherein the skin care product comprises: the skin care product is eye cream which comprises the following components in parts by weight: 50-60 parts of distilled water, 3-5 parts of nameko mushroom mucus, 0.25-0.3 part of soybean oligopeptide, 3-4 parts of polypeptide compound source liquid, 2-4 parts of natural amino acid humectant, 0.3-0.4 part of polyhydric alcohol, 0.5-1 part of tree peony bark extract, 3-5 parts of tremella polysaccharide extract, 1-2 parts of cherry extract, 2-3 parts of asiatic centella extract, 1-2 parts of plant composite anti-allergic factor, 0.6-0.7 part of sclerotium rolfsii gum, 0.05-0.1 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 2-5 parts of hydrogenated starch hydrolysate, 1-2 parts of pomegranate extract, 3-5 parts of emulsifier, 5-10 parts of vegetable oil, 990510-15 parts of organic silicon, 1-3 parts of safflower extract and 2-5 parts of millet extract, 2-4 parts of elderberry extract and 0.5-0.8 part of PE 9010.
9. A beauty food prepared by using the pholiota nameko mucilage of claim 1, wherein the beauty food comprises the following components: the paint comprises the following components in parts by weight: 50-70 parts of purified water, 5-10 parts of pholiota nameko mucilage, 5-10 parts of soybean oligopeptide, 5-10 parts of sea buckthorn stock solution, 5-10 parts of honey and 5-10 parts of blueberry concentrated solution.
10. The beauty food prepared by using the pholiota nameko mucilage of claim 1, according to claim 9, is characterized in that: the beauty food is oral liquid, which comprises the following components in parts by weight: 50-70 parts of purified water, 5-10 parts of pholiota nameko mucilage, 5-10 parts of soybean oligopeptide, 5-10 parts of sea buckthorn stock solution, 5-10 parts of honey and 5-10 parts of blueberry concentrated solution.
CN201911419464.5A 2019-12-31 2019-12-31 Preparation method of pholiota nameko mucilage and skin care product and beauty food prepared from pholiota nameko mucilage Pending CN111000773A (en)

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