CN110946936A - 一种治疗效果好的消炎止痛药膏及其制备方法 - Google Patents
一种治疗效果好的消炎止痛药膏及其制备方法 Download PDFInfo
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- CN110946936A CN110946936A CN201811118246.3A CN201811118246A CN110946936A CN 110946936 A CN110946936 A CN 110946936A CN 201811118246 A CN201811118246 A CN 201811118246A CN 110946936 A CN110946936 A CN 110946936A
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- ointment
- temperature
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- pain
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Abstract
本发明涉及医疗领域，具体涉及种治疗效果好的消炎止痛药膏及其制备方法；其成分：元胡，大黄，蒲黄，丹参，川芎，当归，羌活，白蔹，乌药，穿山甲，土木鳖，象皮，赤芍，甘草，龙骨，乳香，没药，麝香，血竭，全竭和樟脑，本发明所制备的消炎止痛药膏具有治疗周期短、治疗效果好的优点；本发明制备的消炎止痛药膏适合治疗阑尾炎引起的各种并发症，减轻患者的痛苦,本发明制备的消炎止痛药膏同样适合治疗一些外科炎症。
Description
技术领域
本发明涉及医疗领域，具体涉及一种治疗效果好的消炎止痛药膏及其制备方法。
背景技术
阑尾炎是因多种因素而形成的炎性改变，为外科常见病，以青年最为多见，男性多于女性。临床上急性阑尾炎较为常见，各年龄段及妊娠期妇女均可发病。慢性阑尾炎较为少见。现在阑尾炎发病地方经常会出现局部腹膜炎、肿块、热痛等并发症。
现在医院对上述现象，大部分的医生都会采用抗生素进行治疗，极少一部分的医生会使用中药药膏进行处理。
抗生素使用较多时，容易导致肝肾功能损害、菌群失调、抗生素相关性腹泻，以及细菌的耐药性增加、二重感染，甚至是延误病情导致死亡等严重不良反应的发生。
中药药膏治疗上述现象具有一定的效果，但是现有的药膏存在见效慢、治疗周期长、治疗效果不理想现象。
基于此，本发明设计了具体为一种治疗效果好的消炎止痛药膏及其制备方法，以解决上述问题。
发明内容
针对现有技术的不足，本发明提供了一种治疗效果好的消炎止痛药膏，不仅具有见效慢、治疗周期长、治疗效果，还具有能治疗多种并发症等优点。
为实现以上目的，本发明通过以下技术方案予以实现：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡6-24g，大黄6-25g，蒲黄10-30g，丹参10-25g，川芎15-30g，当归10-30g，羌活12-24g，白蔹10-20g，乌药6-20g，穿山甲6-18g，土木鳖20-30g，象皮10-20g，赤芍5-25g，甘草5-15g，龙骨5-30g，乳香3-25g，没药3-25g，麝香2-7g，血竭4-15g，全竭3-12g和樟脑6-24g。
优选的，一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的9.5-12.5倍的纯净水，浸泡，将煎药锅升温至85-95℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.05-0.07MPa，浓缩至温度为75-95℃时相对密度为1.03；继续加热，温度升至95-110℃，相对密度为1.15-1.25，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
优选的，所述步骤b浸泡时间为1.5-2.5h。
优选的，所述步骤b文火煎煮时间为120-140min。
优选的，所述步骤c中的真空浓缩装置处于恒温状态，温度保持在26-35℃。
优选的，所述步骤e中的高温灭菌的温度控制在95 -115℃，蒸汽压力为0.78 -0.85MPa。
有益效果：
本发明以元胡，大黄，蒲黄，丹参，川芎，当归，羌活，白蔹，乌药，穿山甲，土木鳖，象皮，赤芍，甘草，龙骨，乳香，没药，麝香，血竭，全竭和樟脑作为制备消炎止痛药膏的原料，所制备的消炎止痛药膏具有治疗周期短、治疗效果好的优点。本发明制备的消炎止痛药膏适合治疗阑尾炎引起的各种并发症，减轻患者的痛苦。本发明制备的消炎止痛药膏同样适合治疗一些外科炎症。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚，下面将结合本发明实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
实施例1：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡6g，大黄25g，蒲黄10g，丹参25g，川芎15g，当归10g，羌活12g，白蔹20g，乌药6g，穿山甲18g，土木鳖20g，象皮19g，赤芍5g，甘草13g，龙骨5g，乳香25g，没药3g，麝香6g，血竭4g，全竭12g和樟脑20g。
一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的9.5倍的纯净水，浸泡，将煎药锅升温至95℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.05MPa，浓缩至温度为75℃时相对密度为1.03；继续加热，温度升至110℃，相对密度为1.15，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
步骤b浸泡时间为2.5h。
步骤b文火煎煮时间为120min。
步骤c中的真空浓缩装置处于恒温状态，温度保持在35℃。
步骤e中的高温灭菌的温度控制在95 ℃，蒸汽压力为0.78 MPa。
实施例2：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡10g，大黄6g，蒲黄16g，丹参10g，川芎19g，当归30g，羌活15g，白蔹10g，乌药9g，穿山甲15g，土木鳖22g，象皮10g，赤芍10g，甘草11g，龙骨10g，乳香3g，没药9g，麝香5g，血竭7g，全竭3g和樟脑24g。
一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的10.2倍的纯净水，浸泡，将煎药锅升温至85℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至0.07MPa，浓缩至温度为80℃时相对密度为1.03；继续加热，温度升至95℃，相对密度为1.18，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
步骤b浸泡时间为2.2h。
步骤b文火煎煮时间为125min。
步骤c中的真空浓缩装置处于恒温状态，温度保持在26℃。
步骤e中的高温灭菌的温度控制在100℃，蒸汽压力为0.8MPa。
实施例3：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡14g，大黄12g，蒲黄22g，丹参21g，川芎23g，当归15g，羌活18g，白蔹13g，乌药12g，穿山甲6g，土木鳖24g，象皮20g，赤芍15g，甘草9g，龙骨15g，乳香9g，没药15g，麝香5g，血竭10g，全竭10g和樟脑6g。
一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的10.8倍的纯净水，浸泡，将煎药锅升温至88℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.06MPa，浓缩至温度为85℃时相对密度为1.03；继续加热，温度升至100℃，相对密度为1.21，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
步骤b浸泡时间为1.5h。
步骤b文火煎煮时间为130min。
步骤c中的真空浓缩装置处于恒温状态，温度保持在28℃。
步骤e中的高温灭菌的温度控制在105℃，蒸汽压力为0.82MPa。
实施例4：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡18g，大黄16g，蒲黄25g，丹参16g，川芎27g，当归20g，羌活21g，白蔹16g，乌药15g，穿山甲9g，土木鳖27g，象皮13g，赤芍20g，甘草5g，龙骨25g，乳香9g，没药15g，麝香7g，血竭12g，全竭6g和樟脑14g。
一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的11.6倍的纯净水，浸泡，将煎药锅升温至91℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.05MPa，浓缩至温度为90℃时相对密度为1.03；继续加热，温度升至105℃，相对密度为1.21，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
步骤b浸泡时间为1.8h。
步骤b文火煎煮时间为135min。
步骤c中的真空浓缩装置处于恒温状态，温度保持在31℃。
步骤e中的高温灭菌的温度控制在110℃，蒸汽压力为0.84MPa。
实施例5：
一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡24g，大黄20g，蒲黄30g，丹参13g，川芎30g，当归25g，羌活24g，白蔹18g，乌药20g，穿山甲12g，土木鳖30g，象皮16g，赤芍25g，甘草15g，龙骨30g，乳香22g，没药25g，麝香3g，血竭15g，全竭7g和樟脑18g。
一种治疗效果好的消炎止痛药膏，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的12.5倍的纯净水，浸泡，将煎药锅升温至93℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.07MPa，浓缩至温度为95℃时相对密度为1.03；继续加热，温度升至108℃，相对密度为1.25，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
步骤b浸泡时间为2h。
步骤b文火煎煮时间为140min。
步骤c中的真空浓缩装置处于恒温状态，温度保持在33℃。
步骤e中的高温灭菌的温度控制在115℃，蒸汽压力为0.85MPa。
具体治疗案例：
病例1
刘某男 48岁转移性右下腹压痛皮跳痛明显、局部性腹膜炎，血细胞计数1200，经外科诊断为急性阑尾炎并局部性覆膜炎，建议住院进行阑尾切除手术，患者拒绝手术要求保守治疗，后采用本发明实施例1制备的消炎止痛药膏，24h后疼痛减轻，贴3天后又更换继续用至一周后痊愈，至今未复发。
病例2
孙某女 75岁以阑尾周围脓肿包块收住阜阳市人民医院外壳，阑尾点压痛、手可触及阑尾包块的10CM左右，血象高，有全身感染中毒症状，入院前就此症状已在乡镇医院输送抗菌治疗20多天，未好，特转入阜阳市医院继续抗菌素应用消炎治疗10余天，后建议使用本发明实施例2的制备的消炎止痛药膏，使用24h后，包块明显缩小2CM，贴3天更换一次，后续治疗半月后，包块完全消退，痊愈，至今未复发。
病例3
卞某 8岁发热38℃全力纳差右耳垂肿大热痛，诊断为腮腺炎，小孩惧怕打针吃药，后建议使用本发明实施例3的制备的消炎止痛药膏，贴3天更换一次，3天后红肿消退，随之全身发热不适症状好转，继续使用3天痊愈。
病例4
张某 69岁下肢丹毒反复发作，长期使用抗菌素输液治疗，效果不佳，后建议使用本发明实施例4的制备的消炎止痛药膏，3天更换一次，半月后，红肿斑块消退，全身感染症状也随之好转，治愈后至今未复发。
病例5
张某 70岁双膝关节红肿热痛明显，X光片显示双膝关节腔内有积液，并伴有全身症状发热纳差，疼痛不能眠，行走困难，抗菌治疗效果不佳，经我院检查，使用本发明实施例5的制备的消炎止痛药膏，每天更换一次，3个疗程15天，双膝红肿消退，疼痛减轻，能行走，全身症状消失，继续治疗2个疗程10天痊愈，至今未复发。
需要说明的是，在本文中，诸如第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来，而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、物品或者设备所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括所述要素的过程、方法、物品或者设备中还存在另外的相同要素。
以上实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。
Claims (6)
1.一种治疗效果好的消炎止痛药膏，其特征在于，其成分按重量份计：元胡6-24g，大黄6-25g，蒲黄10-30g，丹参10-25g，川芎15-30g，当归10-30g，羌活12-24g，白蔹10-20g，乌药6-20g，穿山甲6-18g，土木鳖20-30g，象皮10-20g，赤芍5-25g，甘草5-15g，龙骨5-30g，乳香3-25g，没药3-25g，麝香2-7g，血竭4-15g，全竭3-12g和樟脑6-24g。
2.根据权利要求1所述的一种治疗效果好的消炎止痛药膏，其特征在于，其制备方法包括以下步骤：
a、分别将各组分置于中药粉碎机中进行粉碎，然后经过研磨机研磨，过100目筛，所得各组分粉末分开保存，备用；
b、将步骤a中元胡、大黄、蒲黄、丹参、川芎、当归、羌活、白蔹、乌药、穿山甲、土木鳖、象皮、赤芍和甘草粉末置于煎药锅中，向煎药锅中加入各粉末总重量的9.5-12.5倍的纯净水，浸泡，将煎药锅升温至85-95℃，文火煎煮，滤去滤渣，得到汤剂；
c、将步骤b中的汤剂置于带有搅拌功能的真空浓缩装置里，减压至 0.05-0.07MPa，浓缩至温度为75-95℃时相对密度为1.03；继续加热，温度升至95-110℃，相对密度为1.15-1.25，浓缩调制得贴膏剂，常温冷却，按照标准剂量涂敷无纺布上；
d、将龙骨，乳香，没药，麝香，血竭，全竭和樟脑置于搅拌釜中进行混合搅拌，得到混合粉末；
e、将步骤d的混合粉末均匀喷洒在药膏表面，然后进行高温灭菌，杀菌结束后装袋，即得成品。
3.据权利要求2所述的一种治疗效果好的消炎止痛药膏的制备方法，其特征在于：所述步骤b中浸泡时间为1.5-2.5h。
4.据权利要求2所述的一种治疗效果好的消炎止痛药膏的制备方法，其特征在于：所述步骤b中文火煎煮时间为120-140min。
5.据权利要求2所述的一种治疗效果好的消炎止痛药膏的制备方法，其特征在于：所述步骤c中的真空浓缩装置处于恒温状态，温度保持在26-35℃。
6.据权利要求2所述的一种治疗效果好的消炎止痛药膏的制备方法，其特征在于：所述步骤e中的高温灭菌的温度控制在95 -115℃，蒸汽压力为0.78 -0.85MPa。
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| CN1810286A (zh) * | 2005-01-26 | 2006-08-02 | 孙炳阳 | 一种外敷膏药 |
| CN102247518A (zh) * | 2011-07-02 | 2011-11-23 | 郑州新悦医药科技有限公司 | 一种中药贴剂 |
| CN104056018A (zh) * | 2014-06-25 | 2014-09-24 | 姬光勤 | 通络消炎止痛膏 |
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| CN1810286A (zh) * | 2005-01-26 | 2006-08-02 | 孙炳阳 | 一种外敷膏药 |
| CN102247518A (zh) * | 2011-07-02 | 2011-11-23 | 郑州新悦医药科技有限公司 | 一种中药贴剂 |
| CN104056018A (zh) * | 2014-06-25 | 2014-09-24 | 姬光勤 | 通络消炎止痛膏 |
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