CN110934784A - Natural herbal special itching-relieving and miliaria-removing water for infants - Google Patents

Natural herbal special itching-relieving and miliaria-removing water for infants Download PDF

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Publication number
CN110934784A
CN110934784A CN201811116554.2A CN201811116554A CN110934784A CN 110934784 A CN110934784 A CN 110934784A CN 201811116554 A CN201811116554 A CN 201811116554A CN 110934784 A CN110934784 A CN 110934784A
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essence
infants
water
itching
miliaria
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CN201811116554.2A
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Chinese (zh)
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权力敏
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Yuansui Biotechnology Shanghai Co Ltd
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Yuansui Biotechnology Shanghai Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to natural herbal itching-relieving prickly heat-removing water special for infants, which mainly comprises calendula essence water, peach leaf essence, chamomile essential oil, aloe essence, honeysuckle flower extract, ginseng stem cell extract and compound lysozyme. The natural herbage is prepared by extracting, screening and matching through experiments and a special process. The invention aims to provide the infant special itching relieving and miliaria removing water extracted from herbaceous plants by 100%, combines the ginseng stem cell extract and the high-tech components of the lysozyme to quickly remove miliaria, can effectively relieve itching and sterilize, protects delicate skin of infants, and has the functions of safety and no toxicity to infants, no pollution to the environment, no damage to articles, natural plant fragrance, peculiar smell removal and the like.

Description

Natural herbal special itching-relieving and miliaria-removing water for infants
The invention relates to natural herbal itching-relieving prickly heat-removing water special for infants, which mainly comprises calendula essence water, peach leaf essence, chamomile essential oil, aloe essence, honeysuckle flower extract, ginseng stem cell extract and compound lysozyme. The natural herbage is prepared by extracting, screening and matching through experiments and a special process. The infant itching-relieving and heat-rash-removing product in the market at present mainly comprises heat rash powder, wherein the main component of the heat rash powder is talcum powder, and the talcum powder contains inseparable lead which cannot be excreted quickly after entering the body of an infant. When the infant powder is accumulated in a human body for a long time, nerves, a hematopoietic system and a digestive system are damaged, and the intelligence and the physical development of the infant are seriously influenced. In addition, prickly heat powder easily causes excessive dust to be inhaled into the lung to cause lead poisoning, which affects intelligence development and causes allergic infantile asthma. At present, "floral water", "prickly heat water" and the like in the market generally contain high alcohol, and have strong stimulation to the skin of children. The invention aims to provide the infant special itching relieving and miliaria removing water extracted from herbaceous plants by 100%, combines the ginseng stem cell extract and the high-tech components of the compound lysozyme to quickly remove miliaria, can effectively relieve itching and sterilize, protects delicate skin of infants, and has the functions of safety and innocuity to infants, no pollution to environment, no damage to articles, natural faint scent of plants, peculiar smell removal and the like.
Background artduring hot and humid seasons, the human body has to discharge a lot of sweat. When sweat cannot be evaporated rapidly, excessive sweat can block sweat pores or sweat gland ducts, and the sweat continuously secreted under the blockage is retained in the skin, so that miliaria is formed. For newborns, heat rash is more likely to occur because their skin appendages are not fully developed, making sweat pores more likely to be blocked. Miliaria usually occurs in the neck, chest, back, elbows, popliteal fossa, etc., and children may occur in the head, forehead, etc. Initially the skin reddens and then needle-sized red papules or papules, densely flaked, with some papules purulent. Itching and pain after miliaria occur, sometimes a large amount of hot and spicy burning pain and the like exist, and the baby is easy to catch and suffer from secondary infection. The products such as cooling oil on the market are generally oily, certain components of the products have the functions of excitation and anesthesia, and the products are oily and not easy to volatilize, so children can easily touch eyes and mouths after the products are used. Aiming at the problems, the calendula essence water is adopted as a solvent, all antibacterial components are derived from natural herbal biological extracts, the calendula essence water is water-soluble and volatile, and can be volatilized immediately after being applied to children.
The key point of the invention is that a plurality of natural herbal essences are used, and the synergistic effect of plant stem cells and compound lysozyme is matched, so that the effect of each effective component is strongest, the delicate skin of the infant cannot be damaged, and the effects of resisting bacteria, disinfecting, removing peculiar smell and the like are achieved while miliaria and itching are removed.
The formula selected by the invention is as follows (components and weight percentage): 2.0-6.0 parts of peach leaf essence; 2.0-6.0 parts of chamomile essential oil; 2.0-6.0 parts of aloe essence; 2.0-6.0 parts of honeysuckle flower extract; 1.0-3.0% of ginseng stem cell extract; 2.0-6.0 of compound lysozyme; calendula essence water is added to 100.
The calendula extract can sterilize, astringe wounds, treat inflammation, pimples, large pores and other problems; can also calm the skin and improve the sensitive skin; meanwhile, the product can also moisten dry lips and promote the metabolism of skin; especially has good moistening effect on dry skin. The main active ingredient of the calendula is a carotenoid compound, the content of the carotenoid compound accounts for about 3 percent of the dry flowers, and the carotenoid compound mainly comprises lutein, zeaxanthin, carotene, a large amount of lutein esters and the like. The herba Sidae Rhombifoliae further contains volatile oil, saponin, flavonol glycoside and terpenoids. The use of calendula extracts has a long history and has been used in the middle of europe for the treatment of varicose veins, bedsores and skin diseases, for a long time in the form of ointments for various emergency treatments. The calendula extract has anti-inflammatory and antibacterial effects, and especially has good effects on staphylococcus and streptococcus; based on the proliferation of epidermal cells and dermal cells by calendula extract, the inhibition of elastase activity, combined with its excellent antioxidant properties, thus enhancing skin activity, and being used in anti-aging and anti-aging cosmetics; calendula officinalis has a certain moisturizing effect; it also has certain promoting effect on fat decomposition, and can be used as weight reducing agent.
The folium Persicae is leaf of Prunus persica of Rosaceae, contains chemical components such as ursolic acid and hesperetin, and has antibacterial, antiviral, antioxidant, anticancer, speckle removing, skin oil balancing, and cutin softening effects. The flos Persicae contains kaempferol and coumarins. The flos persicae contains trifolin. The flower bud contains naringenin. Diuresis; promoting blood circulation and removing blood stasis. Can sterilize and moisturize.
27 triterpene compounds with anti-inflammatory effect can be separated from flos Matricariae Chamomillae essential oil, and can be used for treating dermatitis and inhibiting skin induced allergy; can enhance capillary resistance, inhibit capillary permeability, and has antiinflammatory effect; simultaneously, the composition can eliminate free radicals, has oxidation resistance and has the effect of delaying aging; has certain inhibiting effect on melanocyte, and has certain whitening and speckle removing effects. It contains volatile oil, flavonoid, amino acids, chlorogenic acid, trace elements, etc. The chrysanthemum extract has biological activities of antibiosis, antioxidation, anti-inflammation, relieving, anti-allergy and the like, is widely applied to cosmetics, and has the effects of preventing allergy, preserving moisture, preventing and treating acne, resisting aging and the like.
Aloe vera essence shows various biological activities and is an important additive for cosmetics. The promotion effect on the growth of fibrin, the inhibition on elastin, the synthesis of collagen and the removal effect on free radicals show that the collagen has good skin-activating and anti-aging effects; has effects in promoting cholesterol synthesis, changing sebum composition, reducing gloss, and improving skin softness; it also has antibacterial, antiinflammatory and moisture keeping effects.
The caffeotannic acid contained in the honeysuckle flower extract has strong antibacterial, fat reducing, skin caring and skin aging preventing effects. The luteolin has antibacterial and antiinflammatory effects, has strong skin penetration, can reach deep skin, and can inhibit hyaluronidase activity, prolong the activity of the product, eliminate free radicals, and absorb ultraviolet, so as to inhibit and eliminate skin color spot, especially senile plaque.
The ginseng stem cell extract can inhibit the decomposition of collagen, promote the synthesis of collagen, repair skin cells damaged by ultraviolet rays and regenerate the damaged cells; help to form new keratin cells, make aged stratum corneum shed, activate new skin keratinocyte; proliferating to form fibroblast for maintaining skin elasticity, and making skin elastic; inhibiting the formation of active oxygen, eliminating the active oxygen and delaying the natural aging of skin cells; it has effects in dilating skin capillary, supplementing nutrition, regulating water and oil balance, keeping moisture, resisting wrinkle, inhibiting melanin formation, and whitening and smoothing skin.
The compound lysozyme is a part of an in vivo immune system and can effectively kill gram-positive bacteria. The complex lysozyme binds to the bacterial surface, reducing the negative charge and assisting phagocytosis of the bacteria. The complex lysozyme attacks the peptidoglycan, a component of the bacterial cell wall, hydrolyzing the glycosidic bond linking the fourth carbon atom of N-acetylmuramic acid and N-acetylglucosamine. Complex lysozyme binds to peptidoglycan molecules through the "groove" between its two domains; the substrate then forms a transition state conformation in the enzyme. The complex lysozyme binds to the dextranase according to the Phillips mechanism. The complex lysozyme then twisted the fourth sugar on the dextran hexaose into a half-chair conformation. In this distorted state (higher energy), the glycosidic bond is easily broken. Thereby achieving the sterilization effect.
The preparation method of the product of the invention comprises the following steps:
(1) preparing an oil phase component: respectively preparing chamomile essential oil, peach leaf essence, honeysuckle flower extract and ginseng stem cell extract according to a proportion, and uniformly mixing;
(2) preparing an aqueous phase component: adding aloe essence and compound lysozyme into part of calendula essence water in proportion, dissolving and stirring;
(3) heating the water phase component to 40 ℃, slowly adding the oil phase component, and emulsifying uniformly;
(4) adding calendula essence water to 100;
(5) randomly performing spot inspection, subpackaging, labeling and sealing after the inspection is qualified.
The invention has the following advantages:
1. the compound lysozyme and the natural plant essence have synergistic effect, so that the effect of each effective component is strongest, and the delicate skin of the baby is not damaged;
2. the prickly heat removing and itching relieving effect is good, the antibacterial and disinfection effect is obvious, and the prickly heat removing and itching relieving agent has the effect of killing and inhibiting bacteria, fungi and viruses;
3. the moisture retention effect is remarkable, and through experiments, the moisture content of the skin of the product before and after use can be increased by 30%;
4. no toxicity, no stimulation, no corrosiveness, no damage to skin and no pollution to environment;
5. simple process and low cost.
The present invention will be described in further detail with reference to the following examples:
the configuration was carried out according to the data (in% by weight) listed in the following table and the procedure described therein:
the formula I is as follows:
flos Matricariae Chamomillae essential oil 2.0-6.0
2.0-6.0 parts of peach leaf essence
Aloe essence 2.0-6.0
Flos Lonicerae extract 2.0-6.0
Ginseng stem cell extract 1.0-3.0
2.0-6.0 of compound lysozyme
Calendula essence water is added to 100.
And a second formula:
flos Matricariae Chamomillae essential oil 3.0-6.0
Peach leaf essence 4.0-6.0
Aloe essence 5.0-6.0
Flos Lonicerae extract 3.0-6.0
Ginseng stem cell extract 2.0-3.0
Composite lysozyme 4.0-6.0
Calendula essence water is added to 100.
And the formula III:
flos Matricariae Chamomillae essential oil 2.0-5.0
2.0-4.0 parts of peach leaf essence
Aloe essence 2.0-3.0
Flos Lonicerae extract 2.0-5.0
Ginseng stem cell extract 1.0-2.0
2.0-4.0 of compound lysozyme
Calendula essence water is added to 100.
The applicant states that the present invention is illustrated by the above examples of the process of the present invention, but the present invention is not limited to the above process steps, i.e. it is not meant that the present invention must rely on the above process steps to be carried out. It will be apparent to those skilled in the art that any modification of the present invention, equivalent substitutions of selected materials and additions of auxiliary components, selection of specific modes and the like, which are within the scope and disclosure of the present invention, are contemplated by the present invention.

Claims (2)

1. The natural herbal itching-relieving prickly heat-removing water special for infants is characterized by comprising the following components in percentage by weight: peach leaf essence (2.0-6.0); chamomile essential oil (2.0-6.0); aloe essence (2.0-6.0); honeysuckle flower extract (2.0-6.0); ginseng stem cell extract (1.0-3.0); composite lysozyme (2.0-6.0); calendula essence water is added to 100.
2. A preparation method of the special natural herbal antipruritic and miliaria-removing lotion for infants as claimed in claim 1 is characterized by comprising the following steps:
(1) preparing an oil phase component: respectively preparing chamomile essential oil, peach leaf essence, honeysuckle flower extract and ginseng stem cell extract according to a proportion, and uniformly mixing;
(2) preparing an aqueous phase component: adding aloe essence and compound lysozyme into part of calendula essence water in proportion, dissolving and stirring;
(3) heating the water phase component to 40 ℃, slowly adding the oil phase component, and emulsifying uniformly;
(4) adding calendula essence water to 100;
(5) randomly performing spot inspection, subpackaging, labeling and sealing after the inspection is qualified.
CN201811116554.2A 2018-09-25 2018-09-25 Natural herbal special itching-relieving and miliaria-removing water for infants Pending CN110934784A (en)

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CN201811116554.2A CN110934784A (en) 2018-09-25 2018-09-25 Natural herbal special itching-relieving and miliaria-removing water for infants

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Application Number Priority Date Filing Date Title
CN201811116554.2A CN110934784A (en) 2018-09-25 2018-09-25 Natural herbal special itching-relieving and miliaria-removing water for infants

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CN110934784A true CN110934784A (en) 2020-03-31

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840158A (en) * 2020-07-28 2020-10-30 广州葆妍生物科技有限公司 Compound plant prickly heat-removing and itching-relieving liquid
CN113476364A (en) * 2021-07-07 2021-10-08 科丝美诗(中国)化妆品有限公司 Plant extract composition for improving skin microcirculation and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840158A (en) * 2020-07-28 2020-10-30 广州葆妍生物科技有限公司 Compound plant prickly heat-removing and itching-relieving liquid
CN113476364A (en) * 2021-07-07 2021-10-08 科丝美诗(中国)化妆品有限公司 Plant extract composition for improving skin microcirculation and application thereof

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