CN110917384A - Medical dressing with antibacterial and high absorption functions and preparation method thereof - Google Patents
Medical dressing with antibacterial and high absorption functions and preparation method thereof Download PDFInfo
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- CN110917384A CN110917384A CN201911287150.4A CN201911287150A CN110917384A CN 110917384 A CN110917384 A CN 110917384A CN 201911287150 A CN201911287150 A CN 201911287150A CN 110917384 A CN110917384 A CN 110917384A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Abstract
The invention discloses a medical dressing with antibacterial high absorption, which comprises natural gauze, wherein the bottom end of the natural gauze is provided with antibacterial warp strips and antibacterial weft strips, the antibacterial warp strips and the antibacterial weft strips are mutually crossed and woven, fiber layers are bonded below the antibacterial warp strips and the antibacterial weft strips, the bottom of the fiber layer is provided with the collagen layer, the invention has scientific and reasonable structure and safe and convenient use, the natural gauze can be used for conveniently and rapidly absorbing wound exudate, and the toughness of the dressing can be conveniently improved by mutually spinning the antibacterial warp strips and the antibacterial weft strips, and the antibacterial warp strips and the antibacterial weft strips can also ensure the further antibacterial property of the medical dressing, and the fiber layer adopts the mutual matching of the sodium carboxymethyl cellulose fiber and the collagen layer, can promote skin tissue anabolism and cell regeneration, increase skin local temperature and humidity, and accelerate blood circulation and metabolism of local skin cells.
Description
Technical Field
The invention relates to the technical field of medical dressings, in particular to a medical dressing with antibacterial and high absorption and a preparation method thereof.
Background
The medical dressing comprises natural gauze, synthetic fiber dressing, polymeric film dressing, foaming polymeric dressing, hydrocolloid dressing and alginate dressing and is used for covering medical materials of sores, wounds or other damages, with the deep research on the pathophysiology of the wound healing process, people understand the wound healing process more and more deeply, so that the continuous improvement and development of the medical wound dressing are caused, today, compared with the early stage, the novel dressing for wound nursing has revolutionary changes, and the medical dressings with different performances can be selected by clinical nursing personnel;
however, the medical dressing in the current market still has great defects in the aspects of antibiosis and high absorption, and cannot facilitate normal skin attachment and later-period healing of human body and reduce the infection rate of wounds.
Disclosure of Invention
The invention provides a medical dressing with antibacterial and high absorption and a preparation method thereof, which can effectively solve the problems that the medical dressing in the current market still has great defects in the aspects of antibacterial and high absorption, the normal attachment and the later recovery of the skin of a human body cannot be facilitated, and the infection rate of a wound is reduced in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a medical dressing with antibiotic high absorption, includes natural gauze, the natural gauze bottom is provided with antibiotic warp strip and antibiotic weft, antibiotic warp strip and antibiotic weft intercrossing weaving, antibiotic warp strip and antibiotic weft below bond and have the fibrous layer, the fibrous layer bottom is provided with the collagen layer, be provided with the triangle of falling between fibrous layer and the collagen layer, collagen layer bottom is provided with compound dressing, the embedding has antibiotic absorbed layer in the middle of the compound dressing.
According to the technical scheme, the table proportion of the antibacterial warp strips and the antibacterial weft strips is-in.
According to the technical scheme, the antibacterial absorption layer is square, and a chamfer is arranged at the edge of the top end of the antibacterial absorption layer.
According to the technical scheme, the antibacterial warp strips and the antibacterial weft strips are silver-containing dressings.
A preparation method of a medical dressing with antibacterial and high absorption comprises the following steps:
s1, connecting the fiber layer and the collagen layer, and placing the antibacterial warp strips and the antibacterial weft strips at the top ends;
s2, reversely buckling the fiber layer and the collagen layer on the top of the natural gauze;
s3, buckling the collagen layer on the top of the collagen layer;
s4, pasting a composite dressing in the center of the medical dressing;
and S5, applying an antibacterial absorption layer at the center of the front surface of the medical dressing.
According to the technical scheme, the fiber layer is sodium carboxymethyl cellulose fiber, and the preparation method of the sodium carboxymethyl cellulose fiber comprises the following steps:
a1, conveying the pulverized cotton pulp into a vertical alkalizer filled with isopropanol, and adding a sodium hydroxide solution for alkalization while stirring;
a2, alkalizing, conveying the materials to a vertical etherification machine by a pump, and adding an isopropanol solution of chloroacetic acid;
and A3, carrying out etherification reaction among alkali cellulose molecules after etherification to obtain the carboxymethyl.
According to the technical scheme, the concentration of the sodium hydroxide solution in the step A1 is 40% -50%, and the alkalization temperature is 15-25 ℃.
According to the technical scheme, the composite dressing comprises a material which is formed by combining various forms of alginic acid fibers, water-soluble polymers, non-woven textile materials, polyurethane foam and films and has hygroscopicity and protective performance.
According to the technical scheme, the antibacterial absorption layer is formed by matching sodium carboxymethyl cellulose and alginate;
the alginate preparation steps are as follows:
b1, putting the sodium alginate and the potassium alginate into a reaction kettle, and starting blending;
b2, then accelerating the stirring speed and continuing blending;
b3, draining the mixed material, and removing bubbles;
in the step B1, the stirring speed is 10-15r/min, and the stirring time is 10-15 s;
and B2, stirring at the speed of 60-120r/min for 50-70 s.
According to the technical scheme, the ratio of the sodium alginate to the potassium alginate is 1: (0.9-1.3).
Compared with the prior art, the invention has the beneficial effects that: the alginate dressing has the advantages of scientific and reasonable structure, safe and convenient use, convenient and rapid absorption of wound exudate through natural gauze, convenient and further improvement of the toughness of the dressing through the mutual spinning of the antibacterial warp strips and the antibacterial weft strips, and guarantee of the further antibacterial property of the medical dressing through the mutual spinning of the antibacterial warp strips and the antibacterial weft strips, and the mutual matching of the carboxymethyl cellulose sodium fibers and the collagen layers adopted by the fiber layers can facilitate the promotion of skin tissue anabolism and cell regeneration, improve the local temperature and humidity of skin, accelerate the blood circulation and metabolism of local skin cells, and facilitate the regeneration of skin cells, so that the tissue regeneration and repair are accelerated.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
In the drawings:
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of an installation structure of an antibacterial warp strip and an antibacterial weft strip of the present invention;
FIG. 3 is a schematic cross-sectional structural view of the present invention;
FIG. 4 is a schematic flow diagram illustrating the preparation of a medical dressing according to the present invention;
FIG. 5 is a schematic view of the flow structure of the preparation method of sodium carboxymethyl cellulose fiber of the present invention;
FIG. 6 is a schematic view of the process for preparing the antibacterial absorbent layer of the present invention;
reference numbers in the figures: 1. natural gauze; 2. antibacterial warp strips; 3. antibacterial weft; 4. a fibrous layer; 5. a collagen layer; 6. a reverse triangle; 7. a composite dressing; 8. an antibacterial absorbing layer.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
Example 1: as shown in figures 1-3, the invention provides a technical scheme, the medical dressing with antibacterial and high absorption comprises a natural gauze 1, an antibacterial warp strip 2 and an antibacterial weft strip 3 are arranged at the bottom end of the natural gauze 1, the antibacterial warp strip 2 and the antibacterial weft strip 3 are silver-containing dressings, the antibacterial warp strip 2 and the antibacterial weft strip 3 are woven in a mutually crossed mode, the case ratio of the antibacterial warp strip 2 to the antibacterial weft strip 3 is 4:7, a fiber layer 4 is bonded below the antibacterial warp strip 2 and the antibacterial weft strip 3, a collagen layer 5 is arranged at the bottom end of the fiber layer 4, an inverted triangle 6 is arranged between the fiber layer 4 and the collagen layer 5, a composite dressing 7 is arranged at the bottom end of the collagen layer 5, an antibacterial absorption layer 8 is embedded in the middle of the composite dressing 7, the antibacterial absorption layer 8 is square, and a chamfer is arranged at the edge of the top end.
The working principle and the using process of the invention are as follows: in use, the natural gauze 1 can be convenient for absorb wound exudate rapidly, the antibacterial warp strips 2 and the antibacterial weft strips 3 are woven mutually, the toughness of the dressing can be improved more conveniently, the antibacterial warp strips 2 and the antibacterial weft strips 3 can also ensure the further antibacterial property of the medical dressing, the fiber layer 4 adopts sodium carboxymethylcellulose fiber and the collagen layer 5 to be matched with each other, the anabolism and cell regeneration of skin tissues can be facilitated, the local temperature and humidity of the skin are improved, the blood circulation and metabolism of local skin cells are accelerated, the regeneration of the skin cells is facilitated, the tissue regeneration and repair are accelerated, the main raw materials of the alginate dressing are sodium methylcarbide cellulose and calcium alginate, and the dressing is mainly characterized by having high hygroscopicity, gelling and hemostatic properties, and is convenient for normal skin healing.
Example 2: as shown in figures 1-3, the invention provides a technical scheme, the medical dressing with antibacterial and high absorption comprises a natural gauze 1, an antibacterial warp strip 2 and an antibacterial weft strip 3 are arranged at the bottom end of the natural gauze 1, the antibacterial warp strip 2 and the antibacterial weft strip 3 are silver-containing dressings, the antibacterial warp strip 2 and the antibacterial weft strip 3 are woven in a mutually crossed mode, the case ratio of the antibacterial warp strip 2 to the antibacterial weft strip 3 is 4:5, a fiber layer 4 is bonded below the antibacterial warp strip 2 and the antibacterial weft strip 3, a collagen layer 5 is arranged at the bottom end of the fiber layer 4, an inverted triangle 6 is arranged between the fiber layer 4 and the collagen layer 5, a composite dressing 7 is arranged at the bottom end of the collagen layer 5, an antibacterial absorption layer 8 is embedded in the middle of the composite dressing 7, the antibacterial absorption layer 8 is square, and a chamfer is arranged at the edge of the top end.
The working principle and the using process of the invention are as follows: in use, the natural gauze 1 can be convenient for absorb wound exudate rapidly, the antibacterial warp strips 2 and the antibacterial weft strips 3 are woven mutually, the toughness of the dressing can be improved more conveniently, the antibacterial warp strips 2 and the antibacterial weft strips 3 can also ensure the further antibacterial property of the medical dressing, the fiber layer 4 adopts sodium carboxymethylcellulose fiber and the collagen layer 5 to be matched with each other, the anabolism and cell regeneration of skin tissues can be facilitated, the local temperature and humidity of the skin are improved, the blood circulation and metabolism of local skin cells are accelerated, the regeneration of the skin cells is facilitated, the tissue regeneration and repair are accelerated, the main raw materials of the alginate dressing are sodium methylcarbide cellulose and calcium alginate, and the dressing is mainly characterized by having high hygroscopicity, gelling and hemostatic properties, and is convenient for normal skin healing.
Example 3: as shown in figures 1-3, the invention provides a technical scheme, the medical dressing with antibacterial and high absorption comprises a natural gauze 1, an antibacterial warp strip 2 and an antibacterial weft strip 3 are arranged at the bottom end of the natural gauze 1, the antibacterial warp strip 2 and the antibacterial weft strip 3 are silver-containing dressings, the antibacterial warp strip 2 and the antibacterial weft strip 3 are woven in a mutually crossed mode, the case ratio of the antibacterial warp strip 2 to the antibacterial weft strip 3 is 4:6, a fiber layer 4 is bonded below the antibacterial warp strip 2 and the antibacterial weft strip 3, a collagen layer 5 is arranged at the bottom end of the fiber layer 4, an inverted triangle 6 is arranged between the fiber layer 4 and the collagen layer 5, a composite dressing 7 is arranged at the bottom end of the collagen layer 5, an antibacterial absorption layer 8 is embedded in the middle of the composite dressing 7, the antibacterial absorption layer 8 is square, and a chamfer is arranged at the edge of the top end.
The working principle and the using process of the invention are as follows: in use, the natural gauze 1 can be convenient for absorb wound exudate rapidly, the antibacterial warp strips 2 and the antibacterial weft strips 3 are woven mutually, the toughness of the dressing can be improved more conveniently, the antibacterial warp strips 2 and the antibacterial weft strips 3 can also ensure the further antibacterial property of the medical dressing, the fiber layer 4 adopts sodium carboxymethylcellulose fiber and the collagen layer 5 to be matched with each other, the anabolism and cell regeneration of skin tissues can be facilitated, the local temperature and humidity of the skin are improved, the blood circulation and metabolism of local skin cells are accelerated, the regeneration of the skin cells is facilitated, the tissue regeneration and repair are accelerated, the main raw materials of the alginate dressing are sodium methylcarbide cellulose and calcium alginate, and the dressing is mainly characterized by having high hygroscopicity, gelling and hemostatic properties, and is convenient for normal skin healing.
Example 4: as shown in fig. 4-6, the present invention provides a technical solution, a method for preparing a medical dressing with antibacterial and high absorption, comprising the following steps:
s1, connecting the fiber layer and the collagen layer, and placing the antibacterial warp strips and the antibacterial weft strips at the top ends;
s2, reversely buckling the fiber layer and the collagen layer on the top of the natural gauze;
s3, buckling the collagen layer on the top of the collagen layer;
s4, pasting a composite dressing in the center of the medical dressing;
and S5, applying an antibacterial absorption layer at the center of the front surface of the medical dressing.
According to the technical scheme, the fiber layer is sodium carboxymethyl cellulose fiber, and the preparation method of the sodium carboxymethyl cellulose fiber comprises the following steps:
a1, conveying the pulverized cotton pulp into a vertical alkalizer filled with isopropanol, and adding a sodium hydroxide solution for alkalization while stirring;
a2, alkalizing, conveying the materials to a vertical etherification machine by a pump, and adding an isopropanol solution of chloroacetic acid;
and A3, carrying out etherification reaction among alkali cellulose molecules after etherification to obtain the carboxymethyl.
According to the technical scheme, the concentration of the sodium hydroxide solution in the step A1 is 50%, and the alkalization temperature is 18 ℃.
According to the technical scheme, the composite dressing comprises a material which is formed by combining various forms of alginic acid fibers, water-soluble polymers, non-woven textile materials, polyurethane foam and films and has hygroscopicity and protective performance.
According to the technical scheme, the antibacterial absorption layer is formed by matching sodium carboxymethyl cellulose and alginate;
the alginate preparation steps are as follows:
b1, putting the sodium alginate and the potassium alginate into a reaction kettle, and starting blending;
b2, then accelerating the stirring speed and continuing blending;
b3, draining the mixed material, and removing bubbles;
in the step B1, the stirring speed is 15r/min, and the stirring time is 10 s;
the step B2 is carried out at a stirring speed of 100r/min and a stirring time of 60 s.
According to the technical scheme, the ratio of the sodium alginate to the potassium alginate is 1: 1.
example 5: as shown in fig. 4-6, the present invention provides a technical solution, a method for preparing a medical dressing with antibacterial and high absorption, comprising the following steps:
s1, connecting the fiber layer and the collagen layer, and placing the antibacterial warp strips and the antibacterial weft strips at the top ends;
s2, reversely buckling the fiber layer and the collagen layer on the top of the natural gauze;
s3, buckling the collagen layer on the top of the collagen layer;
s4, pasting a composite dressing in the center of the medical dressing;
and S5, applying an antibacterial absorption layer at the center of the front surface of the medical dressing.
According to the technical scheme, the fiber layer is sodium carboxymethyl cellulose fiber, and the preparation method of the sodium carboxymethyl cellulose fiber comprises the following steps:
a1, conveying the pulverized cotton pulp into a vertical alkalizer filled with isopropanol, and adding a sodium hydroxide solution for alkalization while stirring;
a2, alkalizing, conveying the materials to a vertical etherification machine by a pump, and adding an isopropanol solution of chloroacetic acid;
and A3, carrying out etherification reaction among alkali cellulose molecules after etherification to obtain the carboxymethyl.
According to the technical scheme, the concentration of the sodium hydroxide solution in the step A1 is 45%, and the alkalization temperature is 19 ℃.
According to the technical scheme, the composite dressing comprises a material which is formed by combining various forms of alginic acid fibers, water-soluble polymers, non-woven textile materials, polyurethane foam and films and has hygroscopicity and protective performance.
According to the technical scheme, the antibacterial absorption layer is formed by matching sodium carboxymethyl cellulose and alginate;
the alginate preparation steps are as follows:
b1, putting the sodium alginate and the potassium alginate into a reaction kettle, and starting blending;
b2, then accelerating the stirring speed and continuing blending;
b3, draining the mixed material, and removing bubbles;
in the step B1, the stirring speed is 12r/min, and the stirring time is 13 s;
the step B2 was carried out at a stirring speed of 7r/min and a stirring time of 70 s.
According to the technical scheme, the ratio of the sodium alginate to the potassium alginate is 1: 0.9.
example 6: as shown in fig. 4-6, the present invention provides a technical solution, a method for preparing a medical dressing with antibacterial and high absorption, comprising the following steps:
s1, connecting the fiber layer and the collagen layer, and placing the antibacterial warp strips and the antibacterial weft strips at the top ends;
s2, reversely buckling the fiber layer and the collagen layer on the top of the natural gauze;
s3, buckling the collagen layer on the top of the collagen layer;
s4, pasting a composite dressing in the center of the medical dressing;
and S5, applying an antibacterial absorption layer at the center of the front surface of the medical dressing.
According to the technical scheme, the fiber layer is sodium carboxymethyl cellulose fiber, and the preparation method of the sodium carboxymethyl cellulose fiber comprises the following steps:
a1, conveying the pulverized cotton pulp into a vertical alkalizer filled with isopropanol, and adding a sodium hydroxide solution for alkalization while stirring;
a2, alkalizing, conveying the materials to a vertical etherification machine by a pump, and adding an isopropanol solution of chloroacetic acid;
and A3, carrying out etherification reaction among alkali cellulose molecules after etherification to obtain the carboxymethyl.
According to the technical scheme, the concentration of the sodium hydroxide solution in the step A1 is 40%, and the alkalization temperature is 23 ℃.
According to the technical scheme, the composite dressing comprises a material which is formed by combining various forms of alginic acid fibers, water-soluble polymers, non-woven textile materials, polyurethane foam and films and has hygroscopicity and protective performance.
According to the technical scheme, the antibacterial absorption layer is formed by matching sodium carboxymethyl cellulose and alginate;
the alginate preparation steps are as follows:
b1, putting the sodium alginate and the potassium alginate into a reaction kettle, and starting blending;
b2, then accelerating the stirring speed and continuing blending;
b3, draining the mixed material, and removing bubbles;
in the step B1, the stirring speed is 14r/min, and the stirring time is 12 s;
the step B2 was carried out at a stirring speed of 115r/min and a stirring time of 55 s.
According to the technical scheme, the ratio of the sodium alginate to the potassium alginate is 1: 1.2.
medical dressings made by examples 4-6 were compared and tabulated as follows:
| example 4 | Example 5 | Example 6 | |
| Antibacterial ratio (%) | 85.6 | 84.9 | 84.6 |
| Absorption rate (%) | 81.3 | 80.3 | 80.2 |
By contrast, the medical dressings prepared in examples 1 to 4 have both the antibacterial rate and the absorption rate, but the medical dressing prepared in example 1 has more efficient antibacterial rate and absorption rate, and is more suitable for popularization in production.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A medical dressing with antibacterial high absorption is characterized in that: including natural gauze (1), natural gauze (1) bottom is provided with antibiotic warp strip (2) and antibiotic weft strip (3), antibiotic warp strip (2) and antibiotic weft strip (3) intercrossing weaving, antibiotic warp strip (2) and antibiotic weft strip (3) below bond there are fibrous layer (4), fibrous layer (4) bottom is provided with collagen layer (5), be provided with between fibrous layer (4) and collagen layer (5) down triangle (6), collagen layer (5) bottom is provided with compound dressing (7), the embedding has antibiotic absorbed layer (8) in the middle of compound dressing (7).
2. The medical dressing with antibacterial and high absorption functions as claimed in claim 1, wherein the table ratio of the antibacterial warp strips (2) to the antibacterial weft strips (3) is 4: 4-7.
3. The medical dressing with antibacterial and high absorption functions as claimed in claim 1, wherein the antibacterial absorption layer (8) is square, and a chamfer is arranged at the edge of the top end.
4. The medical dressing with antibacterial and high absorption functions and the preparation method thereof according to claim 1, wherein the antibacterial warp strips (2) and the antibacterial weft strips (3) are silver-containing dressings.
5. The preparation method of the medical dressing with antibacterial and high absorptivity, according to the claims 1 to 4, is characterized by comprising the following steps:
s1, connecting the fiber layer and the collagen layer, and placing the antibacterial warp strips and the antibacterial weft strips at the top ends;
s2, reversely buckling the fiber layer and the collagen layer on the top of the natural gauze;
s3, buckling the collagen layer on the top of the collagen layer;
s4, pasting a composite dressing in the center of the medical dressing;
and S5, applying an antibacterial absorption layer at the center of the front surface of the medical dressing.
6. The preparation method of the medical dressing with antibacterial and high absorption functions as claimed in claim 5, wherein the fiber layer is sodium carboxymethyl cellulose fiber, and the preparation method of the sodium carboxymethyl cellulose fiber is as follows:
a1, conveying the pulverized cotton pulp into a vertical alkalizer filled with isopropanol, and adding a sodium hydroxide solution for alkalization while stirring;
a2, alkalizing, conveying the materials to a vertical etherification machine by a pump, and adding an isopropanol solution of chloroacetic acid;
and A3, carrying out etherification reaction among alkali cellulose molecules after etherification to obtain the carboxymethyl.
7. The method for preparing the medical dressing with antibacterial and high absorption properties according to claim 6, wherein the concentration of the sodium hydroxide solution in the step A1 is 40% -50%, and the alkalization temperature is 15-25 ℃.
8. The method for preparing the medical dressing with antibacterial and high absorptivity according to claim 5, wherein the composite dressing comprises alginic acid fibers, water-soluble polymers, non-woven textile materials, polyurethane foams and films, which are combined to form a material with both hygroscopicity and protective performance.
9. The method for preparing the medical dressing with antibacterial and high absorption functions as claimed in claim 5, wherein the antibacterial absorption layer is formed by compounding sodium carboxymethylcellulose fibers and alginate;
the alginate preparation steps are as follows:
b1, putting the sodium alginate and the potassium alginate into a reaction kettle, and starting blending;
b2, then accelerating the stirring speed and continuing blending;
b3, draining the mixed material, and removing bubbles;
in the step B1, the stirring speed is 10-15r/min, and the stirring time is 10-15 s;
and B2, stirring at the speed of 60-120r/min for 50-70 s.
10. The method for preparing a medical dressing with antibacterial and high absorption functions according to claim 9, wherein the ratio of sodium alginate to potassium alginate is 1: (0.9-1.3).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911287150.4A CN110917384A (en) | 2019-12-14 | 2019-12-14 | Medical dressing with antibacterial and high absorption functions and preparation method thereof |
| PCT/CN2020/116843 WO2021114811A1 (en) | 2019-12-14 | 2020-09-22 | Antibacterial highly absorbent medical dressing and preparation method therefor |
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| CN201911287150.4A CN110917384A (en) | 2019-12-14 | 2019-12-14 | Medical dressing with antibacterial and high absorption functions and preparation method thereof |
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| CN110917384A true CN110917384A (en) | 2020-03-27 |
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| WO (1) | WO2021114811A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021114811A1 (en) * | 2019-12-14 | 2021-06-17 | 浙江惠龙医疗科技股份有限公司 | Antibacterial highly absorbent medical dressing and preparation method therefor |
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| WO2021114811A1 (en) * | 2019-12-14 | 2021-06-17 | 浙江惠龙医疗科技股份有限公司 | Antibacterial highly absorbent medical dressing and preparation method therefor |
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| WO2021114811A1 (en) | 2021-06-17 |
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