CN1080784C - Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology - Google Patents
Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology Download PDFInfo
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- CN1080784C CN1080784C CN 96121462 CN96121462A CN1080784C CN 1080784 C CN1080784 C CN 1080784C CN 96121462 CN96121462 CN 96121462 CN 96121462 A CN96121462 A CN 96121462A CN 1080784 C CN1080784 C CN 1080784C
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- zinc
- calcium alginate
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- nonwoven fabric
- wound dressing
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Abstract
The present invention relates to a new medical product namely an absorptive medical wound dressing with the functions of stopping blood, resisting infection and diminishing inflammation, and a manufacturing technology of the wound dressing. An alginic acid zinc-calcium fiber non-woven fabric is composed of sodium alginate, zinc chloride and calcium chloride. The active wound dressing manufactured by the alginic acid zinc-calcium fiber non-woven fabric has the structure that artificial cotton is arranged on an air permeable rubberized fabric; the alginic acid zinc-calcium fiber non-woven fabric is arranged on the artificial cotton. The present invention has the advantages that the wound dressing has the functions of resisting infection, diminishing inflammation and promoting wounds to heal besides the absorptive hemostatic function of similar products; the wound dressing makes up the defect that the existing similar products have the hemostatic function but have no the functions of resisting infection and diminishing inflammation. The product is capable of satisfying clinical requirements, and has simple manufacturing technology and low cost.
Description
The present invention relates to medical new product absorption styptic anti-infective anti-inflammatory medical wound dressing and manufacture craft thereof.
Background technology of the present invention: Britain Weir BRIT.CAIR company was in 86 years development operation Calcium Alginate fabric nonwoven cloth Wound dressings and throw in city's field boundary, and this product is English by name: existing product of the same race on the calcium.alginatewound.dressing. commodity domestic city of the KALTOSAT. by name field boundary: sea God's absorbable hemostasia series of products.This product is developed by Textile Research Inst., Ministry of Textile Industry, and its hemostatic mechanism mainly is to pass through the sodium calcium ion-exchanged by the alginic acid calcium salt when contacting with body fluid or blood, discharge calcium ion, thereby the accelerate blood process of setting is brought into play rapid anastalsis.Do not have anti-infective antiinflammation owing to the said goods only has anastalsis, stick and be subjected to certain limitation and numerous medical workers are accepted so be used for wound clinically.
Design of the present invention: with the Sodium Alginate is raw material, material viscosity requires below 70cps (as 68,66,60cps), it is made into viscosity is 1200～1500cps spinning solution, this spinning solution filters by three road flannelettes, (aperture is 0.06～0.1mm) directly to clamp-on and consist of the mixing in the aqueous solution of 5%～12% zinc chloride and 5%～12% calcium chloride (this aqueous solution claims solidification liquid) and make and be shaped to the zinc-calcium alginate wet fiber to filtrate by spinning head by measuring pump, the flush away solidification liquid, drawing-off, alcohol are handled, oven dry.Dried fiber is cut into the staple fibre of 5cm, by combing, cross lapping, acupuncture is bonded into certain thickness bulk zinc-calcium alginate fiber nonwoven fabric, is cut into certain specification according to clinical application, sealing, packing, with behind the γShe Xianmiejun for clinical use, thereby reach purpose of the present invention.
Purpose of design of the present invention: the weak point of avoiding background technology to exist, in the Calcium Alginate molecule, introduce zinc again, make into zinc-calcium alginate double salt.Because the existence of zinc after zinc-calcium alginate fiber nonwoven fabric sticks wound, by exchanging with sodium ion, not only also discharges zinc ion when discharging calcium ion.Zinc ion is except that having the prevention infection effect, can also keep epithelial normal physiological function, control epithelial hyperkeratosis, keep the normal reparation of energy epithelial tissue, fibroblastic hyperplasia, epithelium formation, collagen are synthesized the very important effect of all playing.Zinc can also promote the healing of leg ulcer and other damage.Be applicable to canker sore, the healing of post-surgical trauma.So zinc-calcium alginate fiber nonwoven fabric of the present invention had both had anastalsis, anti-infective anti-inflammatory is arranged again and promote the Wound healing effect.
The present invention compares with background technology, and the one, except absorbable hemostasia effect, also have anti-infective anti-inflammatory, promote the Wound healing effect with like product; The 2nd, filled up that existing like product has anastalsis and the shortcoming of not having anti-infective antiinflammation product more can be met clinical needs, and manufacture craft is simple, cost is low.
Embodiment 1: take by weighing 22.5Kg, viscosity is the Sodium Alginate of 70cps, gradation adds in a certain amount of (about 400Kg) pure water, make its abundant swelling, add water to 500Kg, stir evenly, through plate and frame filter press three road press filtrations, the spinning head that is pressed through the 0.08mm aperture by measuring pump directly enters in the solidification liquid of being made up of 10% zinc chloride and 10% calcium chloride, solidifying the molten degree of depth is 35cm, batch wet fiber, the flush away solidification liquid carries out drawing-off, draw ratio is 1: 12, use 95% Ethanol Treatment again, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the staple fibre of 5cm, by the carding machine combing, cross lapping machine is paved into desired thickness, and hand-manipulating of needle thorn is bonded into the bulk zinc-calcium alginate fiber nonwoven fabric again, is cut into certain specification according to clinical application, sealing, γShe Xianmiejun is used in the packing back, and promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Embodiment 2: take by weighing 22.5Kg, viscosity is the Sodium Alginate of 66cps, gradation adds in a certain amount of (about 400Kg) pure water, make its abundant swelling, add water to 500Kg, stir evenly, through plate and frame filter press three road press filtrations, the spinning head that is pressed through the 0.06mm aperture by measuring pump directly enters in the solidification liquid of being made up of 5% zinc chloride and 5% calcium chloride, solidifying the molten degree of depth is 38cm, batch wet fiber, the flush away solidification liquid carries out drawing-off, draw ratio is 1: 1.3, use 95% Ethanol Treatment again, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the staple fibre of 5cm, by the carding machine combing, cross lapping machine is paved into desired thickness, and hand-manipulating of needle thorn is bonded into the bulk zinc-calcium alginate fiber nonwoven fabric again, is cut into certain specification according to clinical application, sealing, γShe Xianmiejun is used in the packing back, and promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Embodiment 3: take by weighing 22.5Kg, viscosity is the Sodium Alginate of 60cps, gradation adds in a certain amount of (about 400Kg) pure water, make its abundant swelling, add water to 500Kg, stir evenly, through plate and frame filter press three road press filtrations, the spinning head that is pressed through the 0.1mm aperture by measuring pump directly enters in the solidification liquid of being made up of 12% zinc chloride and 12% calcium chloride, solidifying the molten degree of depth is 40cm, batch wet fiber, the flush away solidification liquid carries out drawing-off, draw ratio is 1: 1.5, use 95% Ethanol Treatment again, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the staple fibre of 5cm, by the carding machine combing, cross lapping machine is paved into desired thickness, and hand-manipulating of needle thorn is bonded into the bulk zinc-calcium alginate fiber nonwoven fabric again, is cut into certain specification according to clinical application, sealing, γShe Xianmiejun is used in the packing back, and promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Claims (3)
1, a kind of zinc-calcium alginate fiber nonwoven fabric manufacture craft, it is characterized in that: with algae extract Sodium Alginate is raw material, with the pure water is solvent, being made into viscosity is the thickness spinning solution of 120～1500cps, this spinning solution filters by three road flannelettes, filtrate is extruded by measuring pump, and the spinning solution of extruding is that the spinneret of 0.06～0.1mm directly enters the solidification liquid that contains zinc calcium by the aperture, and the coagulating bath degree of depth is 35～40cm, the zinc-calcium alginate fiber that goes out through wet spinning, the flush away solidification liquid carries out drawing-off, and draw ratio is 1: 1.2～1.5, fiber after the drawing-off is with 95% Ethanol Treatment, the centrifugal ethanol that discards is dried, and gets the zinc-calcium alginate fiber of bright and clean softness, above-mentioned dried fibres is cut into the staple fibre of five centimeter length, through combing, cross lapping, acupuncture is bonded into certain thickness bulk nonwoven fabric, be cut into certain specification then, sealing, packing is with supplying clinical practice behind the ray sterilizing.
2, zinc-calcium alginate fiber nonwoven fabric manufacture craft according to claim 1 is characterized in that: the be mixed into homogeneous aqueous solution of solidification liquid for being made up of 5%～12% zinc chloride and 5%～12% calcium chloride.
3, zinc-calcium alginate fiber nonwoven fabric manufacture craft according to claim 1 and 2, it is characterized in that: the viscosity of Calcium Alginate is between 60cps～70cps.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96121462 CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96121462 CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1170564A CN1170564A (en) | 1998-01-21 |
| CN1080784C true CN1080784C (en) | 2002-03-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96121462 Expired - Fee Related CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1080784C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1332081C (en) * | 2005-04-27 | 2007-08-15 | 武汉大学 | Blended fiber of sodium alginate/water soluble chitin, preparation method and application thereof |
| CN100336562C (en) * | 2005-05-13 | 2007-09-12 | 褚省吾 | Ultra strong absorption calcium alginate henatischesis dressing and its preparation method |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8100872B2 (en) | 2002-10-23 | 2012-01-24 | Tyco Healthcare Group Lp | Medical dressing containing antimicrobial agent |
| ES2394111T3 (en) | 2006-04-11 | 2013-01-21 | Tyco Healthcare Group Lp | Wound dressings with antimicrobial and zinc-containing agents |
| CN100457990C (en) * | 2007-04-16 | 2009-02-04 | 青岛大学 | Producing method and use for common and functional calcium alginate fiber |
| CN102172417A (en) * | 2011-02-18 | 2011-09-07 | 褚加冕 | Method for preparing medical calcium alginate filler strips |
| CN102704326B (en) * | 2012-05-25 | 2014-07-02 | 绍兴蓝海纤维科技有限公司 | Preparation method of alginic acid system nonwoven |
| CN106139228A (en) * | 2016-07-29 | 2016-11-23 | 杭州英健生物科技有限公司 | Medical alginic acid zinc functional dressings and preparation method thereof |
| CN108853574B (en) * | 2017-05-10 | 2021-08-03 | 上海交通大学 | Magnesium alloy and zinc alloy wire mixed-woven composite patch and application thereof |
-
1996
- 1996-12-29 CN CN 96121462 patent/CN1080784C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1332081C (en) * | 2005-04-27 | 2007-08-15 | 武汉大学 | Blended fiber of sodium alginate/water soluble chitin, preparation method and application thereof |
| CN100336562C (en) * | 2005-05-13 | 2007-09-12 | 褚省吾 | Ultra strong absorption calcium alginate henatischesis dressing and its preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1170564A (en) | 1998-01-21 |
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