CN109009668A - A kind of anti-infection self-degradation medical dressing of nano antibacterial - Google Patents
A kind of anti-infection self-degradation medical dressing of nano antibacterial Download PDFInfo
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- CN109009668A CN109009668A CN201810977478.8A CN201810977478A CN109009668A CN 109009668 A CN109009668 A CN 109009668A CN 201810977478 A CN201810977478 A CN 201810977478A CN 109009668 A CN109009668 A CN 109009668A
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- Prior art keywords
- antibacterial
- layer
- dressing
- gauze
- nano
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 39
- 230000002924 anti-infective effect Effects 0.000 title claims abstract description 15
- 230000007281 self degradation Effects 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 23
- 239000002245 particle Substances 0.000 claims abstract description 15
- 239000000017 hydrogel Substances 0.000 claims abstract description 10
- 108010022355 Fibroins Proteins 0.000 claims abstract description 6
- 239000008187 granular material Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims abstract description 6
- 238000000465 moulding Methods 0.000 claims abstract description 6
- 239000002121 nanofiber Substances 0.000 claims abstract description 6
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 6
- 229920000742 Cotton Polymers 0.000 claims description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims description 9
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 2
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000010410 layer Substances 0.000 abstract description 33
- 229940124597 therapeutic agent Drugs 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 4
- 238000001816 cooling Methods 0.000 abstract description 3
- -1 external protection Substances 0.000 abstract description 3
- 239000012530 fluid Substances 0.000 abstract description 3
- 238000002955 isolation Methods 0.000 abstract description 3
- 239000002346 layers by function Substances 0.000 abstract description 3
- 244000005700 microbiome Species 0.000 abstract description 3
- 230000001225 therapeutic effect Effects 0.000 abstract description 3
- 239000000428 dust Substances 0.000 abstract description 2
- 206010052428 Wound Diseases 0.000 description 15
- 208000027418 Wounds and injury Diseases 0.000 description 15
- 230000000694 effects Effects 0.000 description 3
- 230000002421 anti-septic effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000010148 water-pollination Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0206—Adhesive bandages or dressings with fluid retention members with absorbent fibrous layers, e.g. woven or non-woven absorbent pads or island dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01021—Non-adhesive bandages or dressings characterised by the structure of the dressing
- A61F13/01029—Non-adhesive bandages or dressings characterised by the structure of the dressing made of multiple layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0213—Adhesive bandages or dressings with fluid retention members the fluid retention member being a layer of hydrocolloid, gel forming material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/022—Adhesive bandages or dressings with fluid retention members having more than one layer with different fluid retention characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/62—Compostable, hydrosoluble or hydrodegradable materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
The anti-infection self-degradation medical dressing of a kind of nano antibacterial disclosed by the invention; including dressing main body and pad pasting; dressing main body is combined by multiple functional layers; including external protection, hydrogel layer, hydrophilic antibacterial layer and natural gauze layer; external protection is semi-permeable membrane or multilayer perforated non-woven fabric; dust, bacterium, microorganism etc. can effectively be completely cut off under the premise of guaranteeing ventilated using physical isolation mode;Hydrogel layer realizes the temperature regulation of dressing, realizes wound cooling;Hydrophilic antibacterial layer can adsorb wound diffusate (tissue fluid, pus etc.) by hydrophilic granules, and can be continued by antibacterial particle antibacterial;Natural gauze layer sticks wound, and medicament slow release circle thereon is formed by silk fibroin nano-fiber moulding, can inject therapeutic agent, when medical dressing sticks wound, can slow releasing pharmaceutical, continuingly act on wound, reach therapeutic purposes.
Description
Technical field
The present invention relates to field of medical article technology, especially a kind of anti-infection self-degradation medical dressing of nano antibacterial.
Background technique
Wound healing is an extremely complex physiology course, and the physical fitness of patient is to determine the internal cause of wound healing,
But the effect of medical dressing is more very important.Medical dressing is a kind of critically important medical textile, with advances in technology with
And the various demands of medical field, the novel medical dressing with certain function more and more attention has been paid to.
The medical dressing now used, mostly antiseptic gauze often have the following problems when in use: 1, therapeutic agent
Overbrushing overlays on antiseptic gauze surface, and the duration is short, and slow release effect is poor, cannot persistently treat to wound;2, lack necessary
Temperature control, especially in the case of a high temperature, not can be effectively controlled wound temperature, be unfavorable for wound recovery;3, adsorption effect
Difference, essentially consists in that medical dressing hydrophily is poor, cannot effectively the absorptive tissue liquid of Fast Persistence or concentrated water etc., be easy to cause wound
Mouth festers;4, it is poor to continue bacteriostasis, is easy to cause bacteria breed, is unfavorable for wound recovery.
Summary of the invention
The present invention is in view of the above-mentioned problems, disclose a kind of anti-infection self-degradation medical dressing of nano antibacterial.
Specific technical solution is as follows:
A kind of anti-infection self-degradation medical dressing of nano antibacterial, including dressing main body and the pad pasting for being set to dressing body peripheral edge,
It is characterized in that, the dressing main body by external protection, hydrogel layer, hydrophilic antibacterial layer and natural gauze layer it is successively compound and
At the natural gauze layer is formed by stacking by least 2 layers natural gauze;
The hydrophilic antibacterial layer includes that the first gauze, disinfection cotton and the second gauze are sequentially overlapped, the disinfection cotton position
Between the first gauze and the second gauze, disinfection cotton has been embedded in hydrophilic granules and antibacterial particle;
Medicament slow release circle is attached on the lower end surface of the natural gauze layer, the medicament slow release circle is in circular ring shape, and quantity is more
It is a;
Further, the external protection is semi-permeable membrane or multilayer perforated non-woven fabric;
Further, the hydrophilic granules are sodium carboxymethylcellulose particle;
Further, the antibacterial particle is nano-Ag particles;
Further, the medicament slow release circle is formed by silk fibroin nano-fiber moulding;
It further, is in be arranged concentrically between multiple medicament slow release circles in circular ring shape;
Further, therapeutic agent is adsorbed on the medicament slow release circle.
The invention has the benefit that
The anti-infection self-degradation medical dressing of a kind of nano antibacterial disclosed by the invention, including dressing main body and pad pasting, dressing main body
It is combined by multiple functional layers, including external protection, hydrogel layer, hydrophilic antibacterial layer and natural gauze layer, external protection are
Semi-permeable membrane or multilayer perforated non-woven fabric can effectively completely cut off powder under the premise of guaranteeing ventilated using physical isolation mode
Dirt, bacterium, microorganism etc.;Hydrogel layer realizes the temperature regulation of dressing, realizes wound cooling;Hydrophilic antibacterial layer can be by hydrophilic
Granular absorption wound diffusate (tissue fluid, pus etc.), and can be continued by antibacterial particle antibacterial;Natural gauze layer sticks wound
Mouthful, medicament slow release circle thereon is formed by silk fibroin nano-fiber moulding, therapeutic agent can be injected, when medical dressing sticks wound
Mouthful when, can slow releasing pharmaceutical, continuingly act on wound, reach therapeutic purposes.
Detailed description of the invention
Fig. 1 is schematic diagram of the present invention.
Fig. 2 is a-quadrant sectional view in Fig. 1.
Fig. 3 is bottom view of the present invention.
Specific embodiment
Clear to be more clear technical solution of the present invention, the present invention is described further with reference to the accompanying drawing,
The technical characteristic of any pair of technical solution of the present invention carries out the scheme that equivalencing is obtained with conventional reasoning and each falls within guarantor of the present invention
Protect range.
A kind of anti-infection self-degradation medical dressing of nano antibacterial as shown in the figure, including dressing main body 1 and it is set to dressing
The pad pasting 2 on 1 periphery of main body, which is characterized in that the dressing main body 1 is by external protection 3, hydrogel layer 4, hydrophilic antibacterial 5 and of layer
Natural gauze layer 6 is sequentially compounding, and the natural gauze layer 6 is formed by stacking by least 2 layers natural gauze;
The hydrophilic antibacterial layer 5 includes that the first gauze 51, disinfection cotton 52 and the second gauze 53 are sequentially overlapped, the disinfection
For cotton 52 between the first gauze 51 and the second gauze 53, disinfection cotton 52 has been embedded in hydrophilic granules 54 and antibacterial particle
55;
Medicament slow release circle 7 is attached on the lower end surface of the natural gauze layer 6, the medicament slow release circle 7 is in circular ring shape, and quantity is
It is multiple;
Further, the external protection 3 is semi-permeable membrane or multilayer perforated non-woven fabric;
Further, the hydrophilic granules 54 are sodium carboxymethylcellulose particle;
Further, the antibacterial particle 55 is nano-Ag particles;
Further, the medicament slow release circle 7 is formed by silk fibroin nano-fiber moulding;
It further, is in be arranged concentrically between multiple medicament slow release circles 7 in circular ring shape;
Further, the basis material of the hydrogel layer 4 is polyacrylic, polyethylene glycol, polyvinyl alcohol, alginates
Or polyvinylpyrrolidone;
Further, therapeutic agent is adsorbed on the medicament slow release circle 7.
A kind of anti-infection self-degradation medical dressing of nano antibacterial of the present embodiment, including dressing main body and pad pasting, dressing master
Body is combined by multiple functional layers, including external protection, hydrogel layer, hydrophilic antibacterial layer and natural gauze layer, external protection
For semi-permeable membrane or multilayer perforated non-woven fabric, can effectively be completely cut off under the premise of guaranteeing ventilated using physical isolation mode
Dust, bacterium, microorganism etc.;Hydrogel layer realizes the temperature regulation of dressing, realizes wound cooling;Hydrophilic antibacterial layer can pass through parent
Particle water adsorbs wound diffusate (tissue fluid, pus etc.), and can be continued by antibacterial particle antibacterial;Natural gauze layer sticks wound
Mouthful, medicament slow release circle thereon is formed by silk fibroin nano-fiber moulding, therapeutic agent can be injected, when medical dressing sticks wound
Mouthful when, can slow releasing pharmaceutical, continuingly act on wound, reach therapeutic purposes.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by anyone skilled in the art,
It should be covered by the scope of protection of the present invention.Therefore, protection scope of the present invention should be with the protection scope of claims
Subject to.
Claims (6)
1. a kind of anti-infection self-degradation medical dressing of nano antibacterial, including dressing main body and the patch for being set to dressing body peripheral edge
Film, which is characterized in that the dressing main body is successively compound by external protection, hydrogel layer, hydrophilic antibacterial layer and natural gauze layer
It forms, the natural gauze layer is formed by stacking by least 2 layers natural gauze;
The hydrophilic antibacterial layer includes that the first gauze, disinfection cotton and the second gauze are sequentially overlapped, the disinfection cotton position
Between the first gauze and the second gauze, disinfection cotton has been embedded in hydrophilic granules and antibacterial particle;
Medicament slow release circle is attached on the lower end surface of the natural gauze layer, the medicament slow release circle is in circular ring shape, and quantity is more
It is a.
2. a kind of anti-infection self-degradation medical dressing of nano antibacterial as described in claim 1, which is characterized in that the outer protection
Layer is semi-permeable membrane or multilayer perforated non-woven fabric.
3. a kind of anti-infection self-degradation medical dressing of nano antibacterial as described in claim 1, which is characterized in that described hydrophilic
Grain is sodium carboxymethylcellulose particle.
4. a kind of anti-infection self-degradation medical dressing of nano antibacterial as described in claim 1, which is characterized in that described antibacterial
Grain is nano-Ag particles.
5. a kind of anti-infection self-degradation medical dressing of nano antibacterial as described in claim 1, which is characterized in that the drug is slow
Circle is released to be formed by silk fibroin nano-fiber moulding.
6. a kind of anti-infection self-degradation medical dressing of nano antibacterial as described in claim 1, which is characterized in that multiple is in annulus
It is in be arranged concentrically between the medicament slow release circle of shape.
Priority Applications (1)
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CN201810977478.8A CN109009668A (en) | 2018-08-27 | 2018-08-27 | A kind of anti-infection self-degradation medical dressing of nano antibacterial |
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CN201810977478.8A CN109009668A (en) | 2018-08-27 | 2018-08-27 | A kind of anti-infection self-degradation medical dressing of nano antibacterial |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110917384A (en) * | 2019-12-14 | 2020-03-27 | 浙江惠龙医疗科技股份有限公司 | Medical dressing with antibacterial and high absorption functions and preparation method thereof |
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US20050147656A1 (en) * | 2001-06-14 | 2005-07-07 | Hemcon, Inc. | Tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan |
CN203252803U (en) * | 2013-05-10 | 2013-10-30 | 中国人民解放军空军总医院 | Antiseep device of catheter puncture point leaking liquid |
CN103800940A (en) * | 2012-11-14 | 2014-05-21 | 天津禹王生物医药科技有限公司 | Hemostatic application and preparation method thereof |
CN104906620A (en) * | 2015-05-15 | 2015-09-16 | 南阳市汇博生物技术有限公司 | Hydrogel antibacterial gauze dressing and preparation method therefor |
CN105030415A (en) * | 2015-07-09 | 2015-11-11 | 嘉恒医药(江苏)有限公司 | Non-oleaginous non-sticky antimicrobial dressing |
CN209500066U (en) * | 2018-08-27 | 2019-10-18 | 中鸿纳米纤维技术丹阳有限公司 | A kind of anti-infection self-degradation medical dressing of nano antibacterial |
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2018
- 2018-08-27 CN CN201810977478.8A patent/CN109009668A/en active Pending
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US20050147656A1 (en) * | 2001-06-14 | 2005-07-07 | Hemcon, Inc. | Tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan |
CN103800940A (en) * | 2012-11-14 | 2014-05-21 | 天津禹王生物医药科技有限公司 | Hemostatic application and preparation method thereof |
CN203252803U (en) * | 2013-05-10 | 2013-10-30 | 中国人民解放军空军总医院 | Antiseep device of catheter puncture point leaking liquid |
CN104906620A (en) * | 2015-05-15 | 2015-09-16 | 南阳市汇博生物技术有限公司 | Hydrogel antibacterial gauze dressing and preparation method therefor |
CN105030415A (en) * | 2015-07-09 | 2015-11-11 | 嘉恒医药(江苏)有限公司 | Non-oleaginous non-sticky antimicrobial dressing |
CN209500066U (en) * | 2018-08-27 | 2019-10-18 | 中鸿纳米纤维技术丹阳有限公司 | A kind of anti-infection self-degradation medical dressing of nano antibacterial |
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CN110917384A (en) * | 2019-12-14 | 2020-03-27 | 浙江惠龙医疗科技股份有限公司 | Medical dressing with antibacterial and high absorption functions and preparation method thereof |
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Application publication date: 20181218 |