CN110913892A - 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 - Google Patents

包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 Download PDF

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Publication number
CN110913892A
CN110913892A CN201880029699.0A CN201880029699A CN110913892A CN 110913892 A CN110913892 A CN 110913892A CN 201880029699 A CN201880029699 A CN 201880029699A CN 110913892 A CN110913892 A CN 110913892A
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lamp
cells
antigen
protein
cell
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CN201880029699.0A
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Chinese (zh)
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特瑞·海兰
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Immunomic Therapeutics Inc
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Immunomic Therapeutics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
CN201880029699.0A 2017-05-02 2018-05-02 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 Pending CN110913892A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762500053P 2017-05-02 2017-05-02
US62/500,053 2017-05-02
US201762561760P 2017-09-22 2017-09-22
US62/561,760 2017-09-22
PCT/US2018/030725 WO2018204534A1 (en) 2017-05-02 2018-05-02 Lamp (lysosomal associated membrane protein) constructs comprising cancer antigens

Publications (1)

Publication Number Publication Date
CN110913892A true CN110913892A (zh) 2020-03-24

Family

ID=62528827

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CN201880029699.0A Pending CN110913892A (zh) 2017-05-02 2018-05-02 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物

Country Status (10)

Country Link
US (2) US12358962B2 (enExample)
EP (1) EP3618854A1 (enExample)
JP (3) JP7222915B2 (enExample)
KR (2) KR20200016224A (enExample)
CN (1) CN110913892A (enExample)
AU (1) AU2018263923B9 (enExample)
BR (1) BR112019023014A2 (enExample)
CA (1) CA3061950A1 (enExample)
IL (2) IL270271B2 (enExample)
WO (1) WO2018204534A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019222281A1 (en) 2018-05-15 2019-11-21 Immunomic Therapeutics, Inc Improved lamp constructs comprising allergens
EP4045528A1 (en) * 2019-10-18 2022-08-24 Immunomic Therapeutics, Inc. Improved lamp constructs comprising cancer antigens
EP4082560B1 (en) * 2021-04-27 2025-02-26 Academia Sinica Prap1 polypeptide for use in treating hypertriglyceridemia
US20250352639A1 (en) 2022-04-10 2025-11-20 Immunomic Therapeutics, Inc. Bicistronic LAMP Constructs Comprising Immune Response Enhancing Genes and Methods of Use Thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040157307A1 (en) * 2001-04-05 2004-08-12 Harris Christopher John Chimeric vaccines
US20090093050A1 (en) * 2007-03-07 2009-04-09 Tzyy-Choou Wu DNA Vaccine Enhancement with MHC Class II Activators
CN101415827A (zh) * 2005-12-09 2009-04-22 阿哥斯医疗公司 产生抗原特异性效应t细胞的方法
CN103596974A (zh) * 2011-04-15 2014-02-19 卡姆普根有限公司 多肽和多核苷酸及其用于治疗免疫相关失调和癌症的用途

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Patent Citations (5)

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US20040157307A1 (en) * 2001-04-05 2004-08-12 Harris Christopher John Chimeric vaccines
US20170065712A1 (en) * 2001-04-05 2017-03-09 The Johns Hopkins University Chimeric vaccines
CN101415827A (zh) * 2005-12-09 2009-04-22 阿哥斯医疗公司 产生抗原特异性效应t细胞的方法
US20090093050A1 (en) * 2007-03-07 2009-04-09 Tzyy-Choou Wu DNA Vaccine Enhancement with MHC Class II Activators
CN103596974A (zh) * 2011-04-15 2014-02-19 卡姆普根有限公司 多肽和多核苷酸及其用于治疗免疫相关失调和癌症的用途

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IL270271B (en) 2022-11-01
JP2023036863A (ja) 2023-03-14
JP2020518613A (ja) 2020-06-25
US12358962B2 (en) 2025-07-15
JP7222915B2 (ja) 2023-02-15
IL297073B2 (en) 2023-12-01
US20250333458A1 (en) 2025-10-30
IL270271B2 (en) 2023-03-01
EP3618854A1 (en) 2020-03-11
JP7657282B2 (ja) 2025-04-04
US20200087365A1 (en) 2020-03-19
KR20200016224A (ko) 2020-02-14
IL297073A (en) 2022-12-01
BR112019023014A2 (pt) 2020-05-19
AU2018263923B2 (en) 2024-08-22
IL270271A (enExample) 2019-12-31
AU2018263923B9 (en) 2024-09-19
WO2018204534A1 (en) 2018-11-08
IL297073B1 (en) 2023-08-01
JP7407902B2 (ja) 2024-01-04
AU2018263923A1 (en) 2019-10-31
KR20240027895A (ko) 2024-03-04
CA3061950A1 (en) 2018-11-08
JP2024037951A (ja) 2024-03-19

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