CN110839641A - 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途 - Google Patents

异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途 Download PDF

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Publication number
CN110839641A
CN110839641A CN201911241170.8A CN201911241170A CN110839641A CN 110839641 A CN110839641 A CN 110839641A CN 201911241170 A CN201911241170 A CN 201911241170A CN 110839641 A CN110839641 A CN 110839641A
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CN
China
Prior art keywords
group
isoxazoline compound
poultry
parasitic
infestation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911241170.8A
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English (en)
Chinese (zh)
Inventor
A.R.赫克罗斯
H.佐勒
A.弗洛奇莱-斯戈格瑙特
B.胡格赫
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Intervet International BV
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Intervet International BV
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Filing date
Publication date
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Publication of CN110839641A publication Critical patent/CN110839641A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CN201911241170.8A 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途 Pending CN110839641A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13199007 2013-12-20
EP13199007.9 2013-12-20
CN201480068597.1A CN105979944A (zh) 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480068597.1A Division CN105979944A (zh) 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途

Publications (1)

Publication Number Publication Date
CN110839641A true CN110839641A (zh) 2020-02-28

Family

ID=49911279

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480068597.1A Pending CN105979944A (zh) 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途
CN201911241170.8A Pending CN110839641A (zh) 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201480068597.1A Pending CN105979944A (zh) 2013-12-20 2014-12-19 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途

Country Status (12)

Country Link
US (4) US10272071B2 (enExample)
EP (2) EP3082806B1 (enExample)
JP (1) JP6506763B2 (enExample)
CN (2) CN105979944A (enExample)
BR (1) BR112016014216B1 (enExample)
ES (2) ES2950885T3 (enExample)
HU (2) HUE055444T2 (enExample)
MX (2) MX376210B (enExample)
PL (2) PL3082806T3 (enExample)
PT (1) PT3082806T (enExample)
RU (1) RU2688167C1 (enExample)
WO (1) WO2015091900A1 (enExample)

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ES2950885T3 (es) 2013-12-20 2023-10-16 Intervet Int Bv Uso de compuestos de isoxazolina en aves de corral
JP6933983B2 (ja) * 2015-06-23 2021-09-08 インターベット インターナショナル ベー． フェー． 衛生化飲料水と共に使用するためのビタミンｅを含有するイソオキサゾリン溶液
WO2018039508A1 (en) * 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
TWI834690B (zh) * 2018-07-18 2024-03-11 美商富曼西公司 用於防治無脊椎動物害蟲之異噁唑啉化合物
TW202012399A (zh) * 2018-09-12 2020-04-01 美商富曼西公司 用於防制無脊椎動物害蟲之異口咢唑啉化合物
WO2020201440A1 (en) * 2019-04-03 2020-10-08 Virbac Low dose fluralaner compositions for protection against parasitic invertebrate pest
BR112022011046A2 (pt) * 2019-12-16 2022-08-23 Intervet Int Bv Composição para controle de piolhos em avinos
MX2022007455A (es) 2019-12-18 2022-08-15 Elanco Tiergesundheit Ag Derivados de isoxazolina como plaguicidas.
KR20230043904A (ko) 2020-07-24 2023-03-31 엘랑코 유에스 인코포레이티드 이속사졸린 화합물 및 이의 중간체의 제조 공정
EP4430947A1 (en) 2023-03-17 2024-09-18 Przedsiebiorstwo Wielobranzowe "Vet-Agro" Sp. Z O.O. Therapeutic use of isoxazoline compounds, composition of isoxazoline compounds and kit for therapeutic use
US11903962B1 (en) * 2023-05-07 2024-02-20 Michael Farber Isoxazoline complexes and compositions thereof

Citations (4)

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CN101778566A (zh) * 2007-08-17 2010-07-14 英特威国际有限公司 异噁唑啉组合物及其作为抗寄生虫药的用途
CN102149695A (zh) * 2008-07-09 2011-08-10 日产化学工业株式会社 异*唑啉取代的苯甲酰胺化合物的制造方法
CN103260620A (zh) * 2010-12-27 2013-08-21 英特维特国际股份有限公司 包含三缩四乙二醇的外用局部异噁唑啉制剂
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

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JP4883296B2 (ja) 2004-03-05 2012-02-22 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778566A (zh) * 2007-08-17 2010-07-14 英特威国际有限公司 异噁唑啉组合物及其作为抗寄生虫药的用途
CN102149695A (zh) * 2008-07-09 2011-08-10 日产化学工业株式会社 异*唑啉取代的苯甲酰胺化合物的制造方法
CN103260620A (zh) * 2010-12-27 2013-08-21 英特维特国际股份有限公司 包含三缩四乙二醇的外用局部异噁唑啉制剂
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

Also Published As

Publication number Publication date
ES2874054T3 (es) 2021-11-04
MX2020010997A (es) 2020-11-09
US20160317502A1 (en) 2016-11-03
EP3082806A1 (en) 2016-10-26
EP3878281A1 (en) 2021-09-15
US10272071B2 (en) 2019-04-30
JP6506763B2 (ja) 2019-04-24
PL3878281T3 (pl) 2023-07-31
PT3082806T (pt) 2021-06-04
JP2016540028A (ja) 2016-12-22
CN105979944A (zh) 2016-09-28
HUE063842T2 (hu) 2024-02-28
PL3082806T3 (pl) 2021-09-13
MX376210B (es) 2025-03-07
HUE055444T2 (hu) 2021-11-29
RU2688167C1 (ru) 2019-05-20
MX2016008119A (es) 2016-09-16
EP3878281B1 (en) 2023-05-24
WO2015091900A1 (en) 2015-06-25
US11304934B2 (en) 2022-04-19
US20220193040A1 (en) 2022-06-23
RU2019114185A (ru) 2019-06-27
BR112016014216B1 (pt) 2022-08-30
US10653675B2 (en) 2020-05-19
RU2016129272A (ru) 2018-01-25
ES2950885T3 (es) 2023-10-16
US12128032B2 (en) 2024-10-29
US20190192486A1 (en) 2019-06-27
BR112016014216A2 (enExample) 2017-08-08
US20200237727A1 (en) 2020-07-30
EP3082806B1 (en) 2021-05-12

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