CN110812434A - Antibacterial cream for reducing irritation and preparation method thereof - Google Patents

Antibacterial cream for reducing irritation and preparation method thereof Download PDF

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CN110812434A
CN110812434A CN201911210381.5A CN201911210381A CN110812434A CN 110812434 A CN110812434 A CN 110812434A CN 201911210381 A CN201911210381 A CN 201911210381A CN 110812434 A CN110812434 A CN 110812434A
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parts
essential oil
extract
cream
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程小平
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Fujian Tongantang Biotechnology Co Ltd
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Abstract

The invention discloses an antibacterial cream for reducing irritation, which comprises the following raw materials in parts by weight: 10-12 parts of aloe extract, 9-11 parts of mint essential oil, 12-14 parts of tea tree essential oil, 5-7 parts of houttuynia cordata extract, 6-10 parts of traditional Chinese medicine extract, 2-6 parts of white vaseline, 0.6-0.8 part of thickening agent, 0.7-0.9 part of defoaming agent and 40-60 parts of deionized water, wherein the defoaming agent is polydimethylsiloxane. According to the antibacterial cream for reducing irritation and the preparation method thereof, the houttuynia cordata extract and the traditional Chinese medicine extracting solution are added, the Chinese herbal medicine property is utilized for sterilization, the aloe extract, the mint essential oil and the tea tree essential oil are added in a matching manner, the pure natural plant essential oil and the natural antibacterial agent are adopted, various skin harmful bacteria are effectively inhibited, discomfort caused by the skin is eliminated, various plant extraction essences are contained, the antibacterial cream is mild and non-irritant, meanwhile, white vaseline is added, the antibacterial cream has a greasy feeling when being in contact with the skin, and the comfort level is higher.

Description

Antibacterial cream for reducing irritation and preparation method thereof
Technical Field
The invention relates to the technical field of antibacterial paste, in particular to antibacterial paste for reducing irritation and a preparation method thereof.
Background
Bacteriostasis, which is commonly used in methods for inhibiting the growth and reproduction of bacteria and fungi, is some antibiotics which can reversibly inhibit the reproduction of bacteria but do not directly kill the bacteria. With the emergence of probiotics, the new mode of inhibiting harmful bacteria by using beneficial thalli, balancing the microecological balance of a host and maintaining health is also referred to. The hazards of antibiotic abuse are manifold and can be resistant to bacteria, i.e., excessive use of antibiotics can make bacteria resistant to them, thereby diminishing or eliminating the antibiotic effect of the antibiotic. Is prepared from the above materials and appropriate amount of excipient (such as vaseline). The different medicinal ointments, such as wintergreen ointment, kudzu ointment, Hualunghugu ointment, have different efficacies and are different from one medicine to another,
the existing antibacterial cream mostly adopts Chinese herbal medicines as raw materials, inhibits bacteria by utilizing the property of the medicine, but the irritation to skin is larger while the property of the medicine of the Chinese herbal medicines inhibits the bacteria, so that skin itch and even erythema are easily caused, and the application of the antibacterial cream is limited to a certain extent.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides the antibacterial cream for reducing irritation and the preparation method thereof, and solves the problems that the traditional antibacterial cream has the drug property of Chinese herbal medicines, inhibits bacteria, has high irritation to skin, and is easy to cause skin itch and even cause erythema.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: a bacteriostatic cream for reducing irritation comprises the following raw materials in parts by weight: 10-12 parts of aloe extract, 9-11 parts of mint essential oil, 12-14 parts of tea tree essential oil, 5-7 parts of houttuynia cordata extract, 6-10 parts of traditional Chinese medicine extract, 2-6 parts of white vaseline, 0.6-0.8 part of thickening agent, 0.7-0.9 part of defoaming agent and 40-60 parts of deionized water.
Preferably, the raw materials comprise the following components in parts by weight: 10 parts of aloe extract, 9 parts of mint essential oil, 12 parts of tea tree essential oil, 5 parts of houttuynia cordata extract, 6 parts of traditional Chinese medicine extract, 2 parts of white vaseline, 0.6 part of thickening agent, 0.7 part of defoaming agent and 40 parts of deionized water.
Preferably, the raw materials comprise the following components in parts by weight: 11 parts of aloe extract, 10 parts of mint essential oil, 13 parts of tea tree essential oil, 6 parts of houttuynia cordata extract, 8 parts of traditional Chinese medicine extract, 4 parts of white vaseline, 0.7 part of thickening agent, 0.8 part of defoaming agent and 50 parts of deionized water.
Preferably, the raw materials comprise the following components in parts by weight: 12 parts of aloe extract, 11 parts of mint essential oil, 14 parts of tea tree essential oil, 7 parts of houttuynia cordata extract, 10 parts of traditional Chinese medicine extract, 6 parts of white vaseline, 0.8 part of thickening agent, 0.9 part of defoaming agent and 60 parts of deionized water.
Preferably, the Chinese medicinal extract comprises one or more of alkannin, liquorice, rhubarb, phellodendron and radix sophorae flavescentis extract.
Preferably, the thickening agent is prepared by one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose and carbomer resin.
Preferably, the defoamer is polydimethylsiloxane.
The invention also discloses a preparation method of the antibacterial paste for reducing stimulation, which comprises the following steps:
s1, weighing the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use;
s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 3-5 min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extracting solution and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 300-500 r/min, wherein the stirring time is 10-20 min;
s3, viscosity adjustment: finally, sequentially adding a thickening agent and a defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 500-700 rpm, stirring for 5-10 min, and adjusting the viscosity of the mixed solution to 40-140 mPa.s;
s4, preparing an ointment: and (4) heating and concentrating the thick mixed solution obtained in the step (S3), controlling the heating temperature at 60-80 ℃, then filtering, collecting filtrate, and further concentrating the filtrate under reduced pressure to obtain the antibacterial cream.
(III) advantageous effects
The invention provides a bacteriostatic cream for reducing irritation and a preparation method thereof. Compared with the prior art, the method has the following beneficial effects: the antibacterial cream for reducing stimulation and the preparation method thereof are characterized in that the antibacterial cream comprises the following raw materials in parts by weight: 10-12 parts of aloe extract, 9-11 parts of mint essential oil, 12-14 parts of tea tree essential oil, 5-7 parts of houttuynia cordata extract, 6-10 parts of traditional Chinese medicine extract, 2-6 parts of white vaseline, 0.6-0.8 part of thickening agent, 0.7-0.9 part of defoaming agent and 40-60 parts of deionized water, and S1 is weighed according to the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use; s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 3-5 min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extracting solution and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 300-500 r/min, wherein the stirring time is 10-20 min; s3, viscosity adjustment: finally, sequentially adding a thickening agent and a defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 500-700 rpm, stirring for 5-10 min, and adjusting the viscosity of the mixed solution to 40-140 mPa.s; s4, preparing an ointment: heating and concentrating the thick mixed liquid obtained in the step S3, controlling the heating temperature at 60-80 ℃, then filtering, collecting filtrate, further concentrating the filtrate under reduced pressure to obtain the antibacterial cream, adding the houttuynia cordata extract and the traditional Chinese medicine extract, sterilizing by utilizing the property of Chinese herbal medicines, adding the aloe extract, the mint essential oil and the tea tree essential oil in a matching manner, adopting pure natural plant essential oil which is also a natural antibacterial agent, effectively inhibiting various skin harmful bacteria, eliminating discomfort caused by the bacteria to the skin, containing various plant extract essences, being mild and non-irritant, and simultaneously adding white vaseline to ensure that the antibacterial cream has a greasy feeling when contacting the skin and has higher comfort level.
Drawings
FIG. 1 is a comparison chart of the antibacterial cream in the market;
FIG. 2 is a comparison chart of the antibacterial cream of the embodiment of the invention;
fig. 3 is a process flow chart of the preparation of the antibacterial cream.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, an embodiment of the present invention provides a technical solution: a bacteriostatic cream for reducing irritation and a preparation method thereof specifically comprise the following embodiments:
example 1
The raw materials comprise by weight: 10 parts of aloe extract, 9 parts of mint essential oil, 12 parts of tea tree essential oil, 5 parts of houttuynia cordata extract, 6 parts of traditional Chinese medicine extract, 2 parts of white vaseline, 0.6 part of thickening agent, 0.7 part of defoaming agent and 40 parts of deionized water.
The invention also discloses a preparation method of the antibacterial paste for reducing stimulation, which comprises the following steps:
s1, weighing the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use;
s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 3min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extract and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 300 revolutions per minute, wherein the stirring time is 10 min;
s3, viscosity adjustment: finally, sequentially adding the thickening agent and the defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 500 revolutions per minute, stirring for 5 minutes, and adjusting the viscosity of the mixed solution to 40 mPa.s;
s4, preparing an ointment: and (4) heating and concentrating the thick mixed solution obtained in the step (S3), controlling the heating temperature at 60 ℃, then filtering, collecting filtrate, and further concentrating the filtrate under reduced pressure to obtain the antibacterial cream.
Example 2
The raw materials comprise by weight: 11 parts of aloe extract, 10 parts of mint essential oil, 13 parts of tea tree essential oil, 6 parts of houttuynia cordata extract, 8 parts of traditional Chinese medicine extract, 4 parts of white vaseline, 0.7 part of thickening agent, 0.8 part of defoaming agent and 50 parts of deionized water.
The invention also discloses a preparation method of the antibacterial paste for reducing stimulation, which comprises the following steps:
s1, weighing the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use;
s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 4min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extract and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 400 revolutions per minute, wherein the stirring time is 15 min;
s3, viscosity adjustment: finally, sequentially adding a thickening agent and a defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 600 revolutions per minute, stirring for 7 minutes, and adjusting the viscosity of the mixed solution to 80 mPa.s;
s4, preparing an ointment: and (4) heating and concentrating the thick mixed solution obtained in the step (S3), controlling the heating temperature at 70 ℃, then filtering, collecting filtrate, and further concentrating the filtrate under reduced pressure to obtain the antibacterial cream.
Example 3
The raw materials comprise by weight: 12 parts of aloe extract, 11 parts of mint essential oil, 14 parts of tea tree essential oil, 7 parts of houttuynia cordata extract, 10 parts of traditional Chinese medicine extract, 6 parts of white vaseline, 0.8 part of thickening agent, 0.9 part of defoaming agent and 60 parts of deionized water.
The invention also discloses a preparation method of the antibacterial paste for reducing stimulation, which comprises the following steps:
s1, weighing the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use;
s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 5min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extract and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 500 revolutions per minute, wherein the stirring time is 20 min;
s3, viscosity adjustment: finally, sequentially adding a thickening agent and a defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 700 revolutions per minute, stirring for 10 minutes, and adjusting the viscosity of the mixed solution to 140 mPa.s;
s4, preparing an ointment: and (4) heating and concentrating the thick mixed solution obtained in the step (S3), controlling the heating temperature at 80 ℃, then filtering, collecting filtrate, and further concentrating the filtrate under reduced pressure to obtain the antibacterial cream.
Comparative experiment
A manufacturer of a certain antibacterial cream respectively selects the antibacterial cream prepared in the examples 1-3 and a market antibacterial cream to carry out a comparison experiment, as can be seen from fig. 1, the antibacterial rate of the antibacterial cream prepared in the examples 1-3 is 99.2%, the irritation is small, and the antibacterial rate of the antibacterial cream in the market is 62.3%, the irritation is large, the effect of the antibacterial cream prepared by the invention is far higher than that of the market antibacterial cream, as can be seen from fig. 2, the antibacterial cream prepared in the example 2 has the best effect, and is a preferred scheme; the other two are acceptable.
In conclusion, the houttuynia cordata thunb extract and the traditional Chinese medicine extracting solution are added, the Chinese herbal medicine property is utilized for sterilization, the aloe extracting solution, the mint essential oil and the tea tree essential oil are added, the pure natural plant essential oil and the natural antibacterial agent are adopted, various harmful strains of skin are effectively inhibited, discomfort caused by the harmful strains to the skin is eliminated, various plant extracting essences are contained, the effects of mildness and no irritation are realized, and meanwhile, white vaseline is added, so that the antibacterial cream has a greasy feeling when being in contact with the skin, and the comfort level is higher.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. A bacteriostatic cream for reducing irritation, comprising: the raw materials comprise by weight: 10-12 parts of aloe extract, 9-11 parts of mint essential oil, 12-14 parts of tea tree essential oil, 5-7 parts of houttuynia cordata extract, 6-10 parts of traditional Chinese medicine extract, 2-6 parts of white vaseline, 0.6-0.8 part of thickening agent, 0.7-0.9 part of defoaming agent and 40-60 parts of deionized water.
2. Bacteriostatic cream for reducing irritation according to claim 1, characterized in that: the raw materials comprise by weight: 10 parts of aloe extract, 9 parts of mint essential oil, 12 parts of tea tree essential oil, 5 parts of houttuynia cordata extract, 6 parts of traditional Chinese medicine extract, 2 parts of white vaseline, 0.6 part of thickening agent, 0.7 part of defoaming agent and 40 parts of deionized water.
3. Bacteriostatic cream for reducing irritation according to claim 1, characterized in that: the raw materials comprise by weight: 11 parts of aloe extract, 10 parts of mint essential oil, 13 parts of tea tree essential oil, 6 parts of houttuynia cordata extract, 8 parts of traditional Chinese medicine extract, 4 parts of white vaseline, 0.7 part of thickening agent, 0.8 part of defoaming agent and 50 parts of deionized water.
4. Bacteriostatic cream for reducing irritation according to claim 1, characterized in that: the raw materials comprise by weight: 12 parts of aloe extract, 11 parts of mint essential oil, 14 parts of tea tree essential oil, 7 parts of houttuynia cordata extract, 10 parts of traditional Chinese medicine extract, 6 parts of white vaseline, 0.8 part of thickening agent, 0.9 part of defoaming agent and 60 parts of deionized water.
5. A bacteriostatic cream for reducing irritation according to claims 1-4, characterized in that: the Chinese medicinal extractive solution comprises one or more of alkannin, Glycyrrhrizae radix, radix et rhizoma Rhei, cortex Phellodendri, and radix Sophorae Flavescentis extractive solution.
6. A bacteriostatic cream for reducing irritation according to claims 1-4, characterized in that: the thickening agent is prepared from one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose and carbomer resin.
7. A bacteriostatic cream for reducing irritation according to claims 1-4, characterized in that: the defoaming agent is polydimethylsiloxane.
8. A preparation method of antibacterial cream for reducing irritation is characterized by comprising the following steps: the method specifically comprises the following steps:
s1, weighing the following raw materials: weighing aloe extract, mint essential oil, tea tree essential oil, houttuynia cordata extract, traditional Chinese medicine extract, white vaseline, a thickening agent, a defoaming agent and deionized water according to the weight components, and selecting for later use;
s2, mixing the raw materials: pouring the aloe extract, the mint essential oil and the tea tree essential oil into a stirring kettle, adding deionized water, stirring for 3-5 min, then sequentially adding the houttuynia cordata extract, the traditional Chinese medicine extracting solution and white vaseline into the mixed solution, and adjusting the rotation speed of the stirring kettle to 300-500 r/min, wherein the stirring time is 10-20 min;
s3, viscosity adjustment: finally, sequentially adding a thickening agent and a defoaming agent into the mixed solution in the S2, adjusting the rotating speed of the stirring kettle to 500-700 rpm, stirring for 5-10 min, and adjusting the viscosity of the mixed solution to 40-140 mPa.s;
s4, preparing an ointment: and (4) heating and concentrating the thick mixed solution obtained in the step (S3), controlling the heating temperature at 60-80 ℃, then filtering, collecting filtrate, and further concentrating the filtrate under reduced pressure to obtain the antibacterial cream.
CN201911210381.5A 2019-11-30 2019-11-30 Antibacterial cream for reducing irritation and preparation method thereof Pending CN110812434A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109999128A (en) * 2019-05-20 2019-07-12 中联和康(厦门)生物科技有限公司 The hundred antibacterial cream of grass of one kind
CN110179877A (en) * 2019-04-09 2019-08-30 长沙康威日用品有限公司 The antibacterial emulsifiable paste of draft

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110179877A (en) * 2019-04-09 2019-08-30 长沙康威日用品有限公司 The antibacterial emulsifiable paste of draft
CN109999128A (en) * 2019-05-20 2019-07-12 中联和康(厦门)生物科技有限公司 The hundred antibacterial cream of grass of one kind

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Application publication date: 20200221