CN101406629A - Buccal tablets for treating painful swelling of gingiva and preparation method thereof - Google Patents
Buccal tablets for treating painful swelling of gingiva and preparation method thereof Download PDFInfo
- Publication number
- CN101406629A CN101406629A CNA2008102277066A CN200810227706A CN101406629A CN 101406629 A CN101406629 A CN 101406629A CN A2008102277066 A CNA2008102277066 A CN A2008102277066A CN 200810227706 A CN200810227706 A CN 200810227706A CN 101406629 A CN101406629 A CN 101406629A
- Authority
- CN
- China
- Prior art keywords
- parts
- buccal tablet
- radix
- pain
- clear paste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a buccal tablet for treating gum swelling and pain and a preparation method thereof, which belong to the technical field of traditional Chinese medicine. The buccal tablet is prepared by the following compositions in certain weight portion: china root, figwort, dendrobe, radix zanthoxyli, radix scutellariae, folium eriobotryae, wild chrysanthemum flower, honeysuckle and peppermint. The preparation method comprises the following steps: extracting volatile oil from the peppermint; decocting other medicines with water; taking and cconcentrating supernatant fluid into clear paste with certain density after concentrated solution is deposited in alcohol; mixing the clear paste with sucrose powder evenly to prepare particles; drying and cooling the particles; injecting the volatile oil of the peppermint into the particles to seal the particles; adding talcum powder and magnesium stearate into the particles to mix evenly; and tabletting the mixture to obtain the buccal tablet. The invention acheives the efficacies of clearing away heat and toxic material, and relieving swelling and pain through the preferred formulation, has significant effect in treating gum swelling and pain with quick healing effect and convenient taking, and can achieve curing aim only by keeping the buccal tablet in mouth.
Description
Technical field
The present invention is specifically related to a kind of buccal tablet that is used for the treatment of gingival swelling and pain and preparation method thereof, belongs to the Chinese medicine technical field.
Background technology
Gingival swelling and pain mostly is the early metaphase symptom of gingival abscess, tooth fork carbuncle, for steaming syndrome on the stomach-fire.And modern medicine mostly is periodontal diseases such as recurrent aphtha, gingivitis.Chinese medicine is thought and is had a liking for food greasy and surfeit flavour or drink and have a liking for suffering, hot injuring one's stomach, excessiveness of stomach-fire, follow through stifling gingiva, and cause red swelling of gingiva, dazzle pain, very then moving blood and cause bleeding from the gum, as＜the collection of experiences of famous physicians in the Ming Dynasty " institute says: " good wine, savoury, fat meat and fine grain; the thing of sweet cunning, to attack on the excess-heat, then dental bed unclear and for swell, for pain, for hemorrhage "." treatise on blood trouble " said again: " dental bed particularly stomach through venation institute around, so all swelling of the gum, epistaxis all is a flaming up of stomach-fire ", so control with eliminating stomach-fire.
The gingival swelling and pain symptom is clinical sees more, clinically sees that generally disease adopts western medicine more, by clinical observation, adopts buccal tablet therapeutic effect of the present invention good.The invention discloses a kind of buccal tablet that is used for the treatment of gingival swelling and pain, it is to be prepared from by certain weight portion proportioning by Rhizoma Smilacis Glabrae, Radix Scrophulariae, Herba Dendrobii, Radix Zanthoxyli, Radix Scutellariae, Folium Eriobotryae, Flos Chrysanthemi Indici, Flos Lonicerae, Herba Menthae, through optimization formula, each medicine share the effect of playing heat-clearing and toxic substances removing, reducing swelling and alleviating pain altogether, therapeutic effect to gingival swelling and pain is remarkable, and curative effect is rapid, and taking convenience, as long as it is contained in the mouth, just can reach the healing purpose.
Summary of the invention
The object of the invention is to provide a kind of buccal tablet that is used for the treatment of gingival swelling and pain, satisfying vast gum disease patient medication, and improves patient's medication environment, and the preparation method of this buccal tablet is provided, to satisfy the demand that realizes large-scale production.
The present invention is achieved by the following technical solutions:
A kind of buccal tablet that is used for the treatment of gingival swelling and pain, it is that raw material is made by following parts by weight of Chinese traditional medicine material:
20～80 parts of 15～65 parts of Herba Dendrobiis of 55～125 portions of Radix Scrophulariaes of Rhizoma Smilacis Glabrae
30～120 parts of 20～60 parts of Folium Eriobotryaes of 40～100 parts of Radix Scutellariaes of Radix Zanthoxyli
80～150 parts of 40～100 portions of Herba Menthaes of 20～80 portions of Flos Loniceraes of Flos Chrysanthemi Indici
And the weight portion proportioning of described each raw material is:
60 parts of 45 parts of Herba Dendrobiis of 95 portions of Radix Scrophulariaes of Rhizoma Smilacis Glabrae
80 parts of 45 parts of Folium Eriobotryaes of 80 parts of Radix Scutellariaes of Radix Zanthoxyli
120 parts of 70 portions of Herba Menthaes of 60 portions of Flos Loniceraes of Flos Chrysanthemi Indici
The preparation method of this buccal tablet is:
(1) get Herba Menthae, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, decoct with water secondary, each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.20～1.26 (60～70 ℃), cools, and slowly adds ethanol, make and contain alcohol amount and reach 50～70%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.25～1.30 (50～60 ℃), and is standby;
(3) get above-mentioned standby clear paste, add cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add Pulvis Talci and magnesium stearate, mixing, tabletting, promptly.
For beneficial effect of the present invention better is described, we have carried out following pharmacodynamics test and clinical experimental study:
Principal agent side: Rhizoma Smilacis Glabrae 95g, Radix Scrophulariae 45g, Herba Dendrobii 60g, Radix Zanthoxyli 80g, Radix Scutellariae 45g, Folium Eriobotryae 80g, Flos Chrysanthemi Indici 60g, Flos Lonicerae 70g, Herba Menthae 120g makes buccal tablet according to preparation method of the present invention.
One, pharmacodynamics test research
1, test material
(1) medicine and reagent: 1. this buccal tablet; 2. normal saline; 3. rotundine; 4. prednisone sheet; 5. dimethylbenzene.
(2) animal: regular grade NIH mice, male and female half and half.
2, test method and result
(1) bacteriostatic test (tube dilution method) is done continuous 10 the gradient drug level of 10 pipes, is respectively: stock solution, 1: 1,1: 2,1: 4,1: 8,1: 16,1: 32,1: 64,1: 128,1: 256.1. bacterial concentration: Ministry of Public Health reference culture and economize visiting center reference bacterial strain, staphylococcus aureus, colon bacillus, Pseudomonas aeruginosa, staphylococcus epidermidis, Klebsiella pneumonia, Candida albicans.More than each strain be inoculated in meat soup respectively and increase bacterium and reached 900,000,000/ml in 6 hours, dilute 1: 100 times standby, every pipe adds 0.1ml.2. incubation time: every pipe is cultivated and was changeed the blood plate in 18～24 hours and cultivated 18～24 hours again.
Result of the test: this buccal tablet has bacteriostasis to staphylococcus aureus, Pseudomonas aeruginosa, staphylococcus epidermidis, Klebsiella pneumonia stock solution; The minimum antibacterial beach of Candida albicans degree is 1: 2, and streptococcus, colon bacillus drug resistance.
(2) analgesic test (mouse writhing method) gets 40 of healthy mices, body weight 20 ± 2g, male and female half and half are divided into 4 groups (every group each 10) at random, are respectively to be dosage group (6.5g/kg) in blank group, rotundine group and this buccal tablet and high dose group (13.0g/kg).Each group is all irritated stomach 7d with relative medicine except that the blank group, and 1 time/d, behind the last administration 60min, animal is by every mice 0.2ml lumbar injection 0.6% acetic acid, and that observes mice in the 15min turns round the body number of times, and calculates and turn round the body suppression ratio.The result shows: the mouse writhing due to this buccal tablet Dichlorodiphenyl Acetate has obvious suppression effect (P＜0.05), shows that it has significant analgesic activity, and result of the test sees Table 1.
This buccal tablet of table 1 to the result of the test of mice analgesic activity (x ± s, n=10)
Compare with matched group: * P＜0.05, * * P＜0.01.
(3) 48 mices are got in anti-inflammation detumescence test (mice auricular concha swelling method), body weight 20 ± 2g, male and female half and half are divided into 4 groups (every group each 12) at random, are respectively dosage group (6.5g/kg) and high dose group (13.0g/kg) in blank group, prednisone group and this buccal tablet.Every Mus auris dextra shell melted paraxylene 0.02ml, behind the 30min, the auris dextra shell is embrocated relative medicine 1 time.1.5h after applying medicinal lotion or ointment cuts auricular concha, makes normal control with left auricular concha, gets auricle with the 8mm card punch, weigh, and be auricular concha swelling degree with left and right sides auricle weight difference.Result and blank group are carried out statistics relatively, and the result shows: the mice auricular concha swelling due to this buccal tablet xylol has obvious suppression effect (P＜0.05), shows that it has the resist inflammation on repercussive function of highly significant, the results are shown in Table 2.
This buccal tablet of table 2 to the inhibiting result of the test of mice ear (x ± s, n=12)
Annotate: compare * P＜0.05, * * P＜0.01 with the blank group
3, sum up
To sum up the test of pesticide effectiveness is described, has confirmed that this buccal tablet has certain inhibitory action to pathogenic bacterias such as staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans; Mouse writhing due to the Dichlorodiphenyl Acetate and the mice auricular concha swelling due to the xylol all have the obvious suppression effect, have shown that this buccal tablet has the effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, also provide pharmacological basis for clinical research simultaneously.
Two, preliminary clinical research data
1, the physical data object of observation is the out-patient, and all cases are simple gingival swelling and pain, at random 60 routine patients is divided into two groups, each 30 example of this buccal tablet treatment group and matched group, male 12 examples are organized in treatment, women 18 examples, 18～75 years old age, average 45 years old, the course of disease 5 days～2 months; Matched group man 14 examples, women 16 examples, 15～72 years old age, average 42 years old, the course of disease 2 days～1 month.
2, Therapeutic Method treatment group adopts and sucks this buccal tablet, 1 time 2 (about 0.6g), 2 times on the 1st; Matched group adopts the each 0.4g of acetylspiramycin tablet, and 3 times on the 1st, it is each 0.2 to add Metronidazole Tablet, every day 3 times; Two groups of observations were 1 course of treatment with 3～7 days all.
3, in the treatment group as a result 3～5 days, red swelling of gingiva disappears, and pain is ended, and tooth non-loosening, gingiva face shaping recover normal, no gingival hemorrhage and purulence thing, and body temperature and leukocyte are all normal.Matched group was cured in general 5～7 days, and treatment time is long, and not as the thorough treatment of treatment group.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1:
Adopt following prescription:
Rhizoma Smilacis Glabrae 55g Radix Scrophulariae 15g Herba Dendrobii 20g
Radix Zanthoxyli 40g Radix Scutellariae 20g Folium Eriobotryae 30g
Flos Chrysanthemi Indici 20g Flos Lonicerae 40g Herba Menthae 80g
Its preparation method is:
(1) get Herba Menthae 80g, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, and decoct with water secondary, and each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.26 (60 ℃), cools, and slowly adds ethanol, make to contain alcohol amount and reach 50%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.28 (50 ℃), and is standby;
(3) get above-mentioned standby clear paste, add the about 68g of cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add about 10g of Pulvis Talci and the about 8g of magnesium stearate, mixing, tabletting, promptly.
Embodiment 2:
Adopt following prescription:
Rhizoma Smilacis Glabrae 140g Radix Scrophulariae 68g Herba Dendrobii 90g
Radix Zanthoxyli 120g Radix Scutellariae 68g Folium Eriobotryae 120g
Flos Chrysanthemi Indici 90g Flos Lonicerae 105g Herba Menthae 180g
Its preparation method is:
(1) get Herba Menthae 180g, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, and decoct with water secondary, and each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.22 (70 ℃), cools, and slowly adds ethanol, make to contain alcohol amount and reach 60%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.30 (60 ℃), and is standby;
(3) get above-mentioned standby clear paste, add the about 195g of cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add about 38g of Pulvis Talci and the about 22g of magnesium stearate, mixing, tabletting, promptly.
Embodiment 3:
Adopt following prescription:
Rhizoma Smilacis Glabrae 95g Radix Scrophulariae 45g Herba Dendrobii 60g
Radix Zanthoxyli 80g Radix Scutellariae 45g Folium Eriobotryae 80g
Flos Chrysanthemi Indici 60g Flos Lonicerae 70g Herba Menthae 120g
Its preparation method is:
(1) get Herba Menthae 120g, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, and decoct with water secondary, and each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.24 (65 ℃), cools, and slowly adds ethanol, make to contain alcohol amount and reach 55%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.27 (60 ℃), and is standby;
(3) get above-mentioned standby clear paste, add the about 85g of cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add about 21g of Pulvis Talci and the about 11g of magnesium stearate, mixing, tabletting, promptly.
Embodiment 4:
Adopt following prescription:
Rhizoma Smilacis Glabrae 250g Radix Scrophulariae 130g Herba Dendrobii 160g
Radix Zanthoxyli 200g Radix Scutellariae 120g Folium Eriobotryae 240g
Flos Chrysanthemi Indici 160g Flos Lonicerae 200g Herba Menthae 300g
Its preparation method is:
(1) get Herba Menthae 300g, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, and decoct with water secondary, and each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.20 (70 ℃), cools, and slowly adds ethanol, make to contain alcohol amount and reach 70%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.25 (60 ℃), and is standby;
(3) get above-mentioned standby clear paste, add the about 220g of cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add about 64g of Pulvis Talci and the about 36g of magnesium stearate, mixing, tabletting, promptly.
Embodiment 5:
Adopt following prescription:
Rhizoma Smilacis Glabrae 125g Radix Scrophulariae 65g Herba Dendrobii 80g
Radix Zanthoxyli 100g Radix Scutellariae 60g Folium Eriobotryae 120g
Flos Chrysanthemi Indici 80g Flos Lonicerae 100g Herba Menthae 150g
Its preparation method is:
(1) get Herba Menthae 150g, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, and decoct with water secondary, and each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.25 (65 ℃), cools, and slowly adds ethanol, make to contain alcohol amount and reach 65%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.26 (50 ℃), and is standby;
(3) get above-mentioned standby clear paste, add the about 180g of cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add about 24g of Pulvis Talci and the about 16g of magnesium stearate, mixing, tabletting, promptly.
Claims (3)
1, a kind of buccal tablet that is used for the treatment of gingival swelling and pain is characterized in that it is that Chinese crude drug by following weight portion proportioning is that raw material is made:
20～80 parts of 15～65 parts of Herba Dendrobiis of 55～125 portions of Radix Scrophulariaes of Rhizoma Smilacis Glabrae
30～120 parts of 20～60 parts of Folium Eriobotryaes of 40～100 parts of Radix Scutellariaes of Radix Zanthoxyli
80～150 parts of 40～100 portions of Herba Menthaes of 20～80 portions of Flos Loniceraes of Flos Chrysanthemi Indici.
2, a kind of buccal tablet that is used for the treatment of gingival swelling and pain according to claim 1, wherein the weight portion proportioning of each raw material is:
60 parts of 45 parts of Herba Dendrobiis of 95 portions of Radix Scrophulariaes of Rhizoma Smilacis Glabrae
80 parts of 45 parts of Folium Eriobotryaes of 80 parts of Radix Scutellariaes of Radix Zanthoxyli
120 parts of 70 portions of Herba Menthaes of 60 portions of Flos Loniceraes of Flos Chrysanthemi Indici.
3, according to each described a kind of buccal tablet that is used for the treatment of gingival swelling and pain of claim 1-2, its preparation method is:
(1) get Herba Menthae, extract volatile oil, standby;
(2) eight flavors such as all the other Rhizoma Smilacis Glabraes, Radix Scrophulariae mix, decoct with water secondary, each 2 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.20～1.26 (60～70 ℃), cools, and slowly adds ethanol, make and contain alcohol amount and reach 50～70%, fully stir, left standstill the leaching supernatant 12 hours.Residue adds the alcoholic solution washing of corresponding concentration, leaves standstill, and gets supernatant and preceding supernatant and merges, and filters, and decompression filtrate recycling ethanol does not extremely have the alcohol flavor, and is concentrated into the clear paste that relative density is 1.25～1.30 (50～60 ℃), and is standby;
(3) get above-mentioned standby clear paste, add cane sugar powder, mixing is made granule, and drying is put coldly, sprays into Herba Menthae Haplocalycis volatile oil, and airtight 2 hours, add Pulvis Talci and magnesium stearate, mixing, tabletting, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102277066A CN101406629A (en) | 2008-11-28 | 2008-11-28 | Buccal tablets for treating painful swelling of gingiva and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102277066A CN101406629A (en) | 2008-11-28 | 2008-11-28 | Buccal tablets for treating painful swelling of gingiva and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101406629A true CN101406629A (en) | 2009-04-15 |
Family
ID=40569974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008102277066A Pending CN101406629A (en) | 2008-11-28 | 2008-11-28 | Buccal tablets for treating painful swelling of gingiva and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101406629A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836277A (en) * | 2012-09-18 | 2012-12-26 | 成都中医药大学附属医院 | Medicine composition for treating periodontal diseases as well as preparation method and application thereof |
| CN103520549A (en) * | 2013-10-22 | 2014-01-22 | 青岛市市立医院 | Traditional Chinese medical lozenges for treating periodontitis and preparation method thereof |
| CN103520332A (en) * | 2013-10-24 | 2014-01-22 | 吴心怡 | Buccal tablet capable of clearing heat from pharynx and throat and performing anti-inflammation and throat protection and preparation method thereof |
| CN106924629A (en) * | 2017-04-14 | 2017-07-07 | 佛山市海科知识产权交易有限公司 | A kind of Chinese patent medicine tablet for toothache and preparation method thereof |
| CN107115490A (en) * | 2017-06-25 | 2017-09-01 | 长沙善道新材料科技有限公司 | A kind of Chinese patent medicine tablet for being directed to toothache and preparation method thereof |
-
2008
- 2008-11-28 CN CNA2008102277066A patent/CN101406629A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836277A (en) * | 2012-09-18 | 2012-12-26 | 成都中医药大学附属医院 | Medicine composition for treating periodontal diseases as well as preparation method and application thereof |
| CN102836277B (en) * | 2012-09-18 | 2014-01-15 | 成都中医药大学附属医院 | Medicine composition for treating periodontal diseases as well as preparation method and application thereof |
| CN103520549A (en) * | 2013-10-22 | 2014-01-22 | 青岛市市立医院 | Traditional Chinese medical lozenges for treating periodontitis and preparation method thereof |
| CN103520549B (en) * | 2013-10-22 | 2015-11-11 | 青岛市市立医院 | A kind of Traditional Chinese medicine lozenge for the treatment of periodontitis and preparation method thereof |
| CN103520332A (en) * | 2013-10-24 | 2014-01-22 | 吴心怡 | Buccal tablet capable of clearing heat from pharynx and throat and performing anti-inflammation and throat protection and preparation method thereof |
| CN106924629A (en) * | 2017-04-14 | 2017-07-07 | 佛山市海科知识产权交易有限公司 | A kind of Chinese patent medicine tablet for toothache and preparation method thereof |
| CN107115490A (en) * | 2017-06-25 | 2017-09-01 | 长沙善道新材料科技有限公司 | A kind of Chinese patent medicine tablet for being directed to toothache and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102204971B (en) | Traditional Chinese medicine preparation for preventing and treating stomatopathy and throat diseases | |
| CN104547826B (en) | Galangal rhizome extract treats the medical usage of dysmenorrhoea | |
| CN101411782B (en) | Pharmaceutical composition for treating acute pharyngitis and preparation method thereof | |
| CN104435379A (en) | Plant extract compound capable of inhibiting bacteria, resisting inflammation, stopping bleeding and relieving pain and application of plant extract compound | |
| CN108853287B (en) | Pharmaceutical composition for resisting human papilloma virus and gynecological inflammation, gel preparation and application | |
| CN101406629A (en) | Buccal tablets for treating painful swelling of gingiva and preparation method thereof | |
| WO2011035734A1 (en) | Relinqing extract, preparative method and use thereof | |
| CN102485253A (en) | Traditional Chinese medicine composition with characteristics of clearing heat and detoxifying, cooling blood and freeing strangury as well as its preparation method | |
| CN102178753B (en) | Medicinal preparation with effects of clearing heat, purging intense heat, detoxifying, eliminating blood stasis, cooling blood and stopping bleeding | |
| CN102552769A (en) | Medicine for treating vaginitis and preparation method thereof | |
| CN109908194B (en) | Medicine for treating acute and chronic pharyngitis and preparation method thereof | |
| CN104013846A (en) | Traditional Chinese medicine composition for treating dental ulcer and application thereof | |
| CN100356944C (en) | Medicine for relieving-cough and asthma | |
| CN102485254B (en) | Traditional Chinese medicine composition with characteristics of clearing heat and detoxifying, cooling blood and freeing strangury as well as its preparation method | |
| CN100430047C (en) | Chinese medicine composition for peridentitis and preparing method thereof | |
| CN102416066B (en) | Chinese medicinal preparation for treating pharynx and larynx oral disease and preparation method thereof | |
| CN103446564B (en) | Chinese medicine composition of a kind of anti-inflammation and preparation method thereof | |
| CN102397458A (en) | Medicinal composition for treating senile pneumonia and preparation method thereof | |
| CN101310735B (en) | Traditional Chinese drug pelletized granule for reducing fever, detoxifying, diminishing inflammation and preparation method thereof | |
| CN100469378C (en) | Pharmaceutical composition for treating pharyngitis | |
| CN103156988A (en) | Dispersible tablet for clearing heat, relieving sore-throat, detoxifying and relieving pain, and preparation method for same | |
| CN101032558B (en) | Antimicrobial and antipyretic Chinese medicine composition | |
| CN101797263B (en) | Traditional Chinese medicine composite for antibiosis and antiphlogosis | |
| CN101862392B (en) | New pharmaceutical application of cordate houttuynia in thrombus prevention | |
| CN102485241B (en) | Traditional Chinese medicine composition having functions of dispelling wind, clearing heat, removing toxins and benefiting throat and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090415 |