CN110799644A - Cblb核酸内切酶变体、组合物及使用方法 - Google Patents

Cblb核酸内切酶变体、组合物及使用方法 Download PDF

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Publication number
CN110799644A
CN110799644A CN201880042211.8A CN201880042211A CN110799644A CN 110799644 A CN110799644 A CN 110799644A CN 201880042211 A CN201880042211 A CN 201880042211A CN 110799644 A CN110799644 A CN 110799644A
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polypeptide
cell
seq
amino acid
biologically active
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Chinese (zh)
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乔丹·贾儒尔
凯尔·哈文斯
安妮-瑞秋·克罗斯塔格
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Regeneron Pharmaceuticals Inc
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Bluebird Bio Inc
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CN201880042211.8A 2017-05-25 2018-05-25 Cblb核酸内切酶变体、组合物及使用方法 Pending CN110799644A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762511194P 2017-05-25 2017-05-25
US62/511,194 2017-05-25
US201762567417P 2017-10-03 2017-10-03
US62/567,417 2017-10-03
PCT/US2018/034726 WO2018218194A1 (en) 2017-05-25 2018-05-25 Cblb endonuclease variants, compositions, and methods of use

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CN110799644A true CN110799644A (zh) 2020-02-14

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US (4) US12227740B2 (enExample)
EP (1) EP3630962A4 (enExample)
JP (4) JP7191042B2 (enExample)
KR (2) KR102590466B1 (enExample)
CN (1) CN110799644A (enExample)
AU (2) AU2018273979B2 (enExample)
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IL (2) IL270776B2 (enExample)
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IL270776B2 (en) 2017-05-25 2024-11-01 Bluebird Bio Inc Cblb endonuclease variants, compositions, and methods of use
CN112368021B (zh) 2018-06-14 2025-02-21 2赛文缇生物公司 Cd79a嵌合抗原受体
WO2020072059A1 (en) 2018-10-04 2020-04-09 Bluebird Bio, Inc. Cblb endonuclease variants, compositions, and methods of use
JP2022513750A (ja) * 2018-12-10 2022-02-09 ２セブンティ バイオ インコーポレイテッド ホーミングエンドヌクレアーゼバリアント
CA3122094A1 (en) 2018-12-10 2020-06-18 Bluebird Bio, Inc. Pdcd-1 homing endonuclease variants
WO2020123933A1 (en) * 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
MX2021015495A (es) * 2019-06-14 2022-04-18 2Seventy Bio Inc Composiciones y métodos para tratar cáncer.
EP4635972A3 (en) 2020-07-20 2025-12-24 Enanta Pharmaceuticals, Inc. Functionalized peptides as antiviral agents
WO2022109360A1 (en) 2020-11-23 2022-05-27 Enanta Pharmaceuticals, Inc. Novel spiropyrrolidine derived antiviral agents
US11352363B1 (en) 2020-11-23 2022-06-07 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
US11384090B2 (en) 2020-11-23 2022-07-12 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
US12540141B2 (en) 2020-11-23 2026-02-03 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
WO2022140150A1 (en) * 2020-12-21 2022-06-30 2Seventy Bio, Inc. Compositions and methods for site-directed mutagenesis
US11319325B1 (en) 2021-05-11 2022-05-03 Enanta Pharmaceuticals, Inc. Macrocyclic spiropyrrolidine derived antiviral agents
US11325916B1 (en) 2021-07-29 2022-05-10 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
US11339170B1 (en) 2021-07-23 2022-05-24 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents

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