CN110799217A - 季铵化烟酰胺腺嘌呤二核苷酸补救途径抑制剂缀合物 - Google Patents

季铵化烟酰胺腺嘌呤二核苷酸补救途径抑制剂缀合物 Download PDF

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CN110799217A
CN110799217A CN201880042426.XA CN201880042426A CN110799217A CN 110799217 A CN110799217 A CN 110799217A CN 201880042426 A CN201880042426 A CN 201880042426A CN 110799217 A CN110799217 A CN 110799217A
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C·S·诺伊曼
K·奥利瓦
R·里昂
K·P·王
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Seagen Inc
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Seattle Genetics Inc
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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CN201880042426.XA 2017-04-27 2018-04-27 季铵化烟酰胺腺嘌呤二核苷酸补救途径抑制剂缀合物 Pending CN110799217A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762490733P 2017-04-27 2017-04-27
US62/490,733 2017-04-27
US201762573987P 2017-10-18 2017-10-18
US62/573,987 2017-10-18
PCT/US2018/030018 WO2018201087A1 (en) 2017-04-27 2018-04-27 Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates

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CN110799217A true CN110799217A (zh) 2020-02-14

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CN201880042426.XA Pending CN110799217A (zh) 2017-04-27 2018-04-27 季铵化烟酰胺腺嘌呤二核苷酸补救途径抑制剂缀合物

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US (2) US11931414B2 (enExample)
EP (1) EP3615081A1 (enExample)
JP (2) JP7425606B2 (enExample)
KR (1) KR20190141181A (enExample)
CN (1) CN110799217A (enExample)
AU (2) AU2018258687C1 (enExample)
BR (1) BR112019022445A2 (enExample)
CA (1) CA3060206A1 (enExample)
IL (1) IL269794A (enExample)
MA (1) MA51189A (enExample)
MX (2) MX2019012194A (enExample)
SG (1) SG11201909563VA (enExample)
TW (1) TW201904613A (enExample)
WO (1) WO2018201087A1 (enExample)

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CN111454327A (zh) * 2020-04-02 2020-07-28 中国人民解放军第二军医大学 一种nampt蛋白降解靶向嵌合体及其制备方法和应用
CN116092586A (zh) * 2023-03-10 2023-05-09 西北工业大学 一种基于生物电子等排体搜索平台的数据处理方法
CN119219604A (zh) * 2024-09-25 2024-12-31 大连理工大学 一种吡啶季铵盐类fk866前药、其制备方法及应用
WO2025162305A1 (zh) * 2024-02-01 2025-08-07 浙江养生堂天然药物研究所有限公司 含季铵盐的抗体偶联药物及其医药用途

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TWI851531B (zh) 2016-08-09 2024-08-11 美商思進公司 具有改善之生理化學性質之具自我穩定連接子之藥物結合物
CA3039589A1 (en) 2016-10-18 2018-04-26 Seattle Genetics, Inc. Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors
CA3060206A1 (en) 2017-04-27 2018-11-01 Seattle Genetics, Inc. Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates
CN110339181A (zh) * 2019-07-02 2019-10-18 中国药科大学 一种基于点击反应的pH响应型纳米制剂及其制法和应用
AU2021251875A1 (en) * 2020-04-10 2022-11-03 Seagen Inc. Charge variant linkers
WO2024052685A1 (en) 2022-09-09 2024-03-14 MyricX Pharma Limited Cytotoxic imidazo[1,2-a]pyridine compounds and their use in therapy

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